Searching for up to 100 curated homologs for N515DRAFT_0576 FitnessBrowser__Dyella79:N515DRAFT_0576 (330 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

Removed hits that are identical to the query, leaving 11

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Echvi_2001 homoserine kinase (EC 2.7.1.39) from Echinicola vietnamensis KMM 6221, DSM 17526
    43% identity, 91% coverage of query (203 bits)

CA265_RS23470 homoserine kinase (EC 2.7.1.39) from Pedobacter sp. GW460-11-11-14-LB5
    38% identity, 89% coverage of query (177 bits)

hsk / Q8L7R2 homoserine kinase (EC 2.7.1.39) from Arabidopsis thaliana (see paper)
KHSE_ARATH / Q8L7R2 Homoserine kinase; Protein DOWNY MILDEW RESISTANT 1; EC 2.7.1.39 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q8L7R2 homoserine kinase (EC 2.7.1.39) from Arabidopsis thaliana (see 4 papers)
    38% identity, 92% coverage of query (146 bits)

thrB / CAA43213.1 homoserine kinase from Serratia marcescens (see paper)
    33% identity, 87% coverage of query (135 bits)

ThrB / b0003 homoserine kinase (EC 2.7.1.39) from Escherichia coli K-12 substr. MG1655 (see paper)
thrB / P00547 homoserine kinase (EC 2.7.1.39) from Escherichia coli (strain K12) (see 9 papers)
KHSE_ECOLI / P00547 Homoserine kinase; HK; HSK; EC 2.7.1.39 from Escherichia coli (strain K12) (see paper)
thrB / GB|BAB96580.2 homoserine kinase; EC 2.7.1.39 from Escherichia coli (see 2 papers)
    31% identity, 85% coverage of query (126 bits)

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Build an alignment for N515DRAFT_0576 and 5 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

thrB / Q58504 homoserine kinase monomer (EC 2.7.1.39) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
1fwkA / Q58504 Crystal structure of homoserine kinase complexed with adp (see paper)
    28% identity, 80% coverage of query (119 bits)

1h74B Crystal structure of homoserine kinase complexed with ile
    28% identity, 80% coverage of query (119 bits)

1h74A Crystal structure of homoserine kinase complexed with ile
    28% identity, 80% coverage of query (119 bits)

1h73A Crystal structure of homoserine kinase complexed with threonine
    28% identity, 80% coverage of query (119 bits)

1h72C Crystal structure of homoserine kinase complexed with hse
    28% identity, 80% coverage of query (119 bits)

KHSE_METMP / Q6M0H5 Homoserine kinase; HK; HSK; EC 2.7.1.39 from Methanococcus maripaludis (strain S2 / LL) (see paper)
    30% identity, 79% coverage of query (91.3 bits)

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