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Searching for up to 100 curated homologs for N515DRAFT_0878 FitnessBrowser__Dyella79:N515DRAFT_0878 (345 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

CH_124303 alcohol dehydrogenase 1 from Magnaporthe grisea 70-15 (see paper)
    43% identity, 98% coverage of query (255 bits)

NOTN_ASPSM / E1ACQ9 Alcohol dehydrogenase notN; Notoamide biosynthesis cluster protein N; EC 1.1.1.1 from Aspergillus sp. (strain MF297-2) (see 3 papers)
    40% identity, 94% coverage of query (228 bits)

P42328 alcohol dehydrogenase (EC 1.1.1.1) from Geobacillus stearothermophilus (see 8 papers)
1rjwA / P42328 Crystal structure of NAD(+)-dependent alcohol dehydrogenase from bacillus stearothermophilus strain lld-r (see paper)
    38% identity, 94% coverage of query (218 bits)

P12311 Alcohol dehydrogenase; ADH-T; EC 1.1.1.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus)
    38% identity, 94% coverage of query (218 bits)

3piiA Crystal structure of mutant of ht- alcohol dehydrogenase with substrate analogue butyramide
    38% identity, 94% coverage of query (217 bits)

Q6RS93 alcohol dehydrogenase (EC 1.1.1.1) from Parageobacillus thermoglucosidasius (see paper)
    37% identity, 95% coverage of query (216 bits)

patD / A0A075TMP0 neopatulin dehydrogenase from Penicillium expansum (see paper)
PATD_PENEN / A0A075TMP0 Alcohol dehydrogenase patD; Patulin biosynthesis cluster protein D; EC 1.1.1.- from Penicillium expansum (Blue mold rot fungus) (see 8 papers)
    39% identity, 97% coverage of query (215 bits)

PATD_ASPCL / A1CFL1 Alcohol dehydrogenase patD; Patulin synthesis protein D; EC 1.1.1.- from Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) (see 3 papers)
    37% identity, 97% coverage of query (214 bits)

6iqdA / P42327 Crystal structure of alcohol dehydrogenase from geobacillus stearothermophilus (see paper)
    38% identity, 94% coverage of query (201 bits)

4z6kA / Q8GIX7 Alcohol dehydrogenase from the antarctic psychrophile moraxella sp. Tae 123
    34% identity, 96% coverage of query (186 bits)

ADH_MORSE / Q8GIX7 Alcohol dehydrogenase; ADH; EC 1.1.1.1 from Moraxella sp. (strain TAE123) (see 3 papers)
Q8GIX7 alcohol dehydrogenase (EC 1.1.1.1) from Moraxella sp. (see paper)
    34% identity, 93% coverage of query (184 bits)

3s2eA / Q46UZ9 Crystal structure of furx nadh complex 1
    35% identity, 94% coverage of query (180 bits)

furX / Q46UZ9 furfuryl alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see paper)
    35% identity, 94% coverage of query (180 bits)

3s2fE Crystal structure of furx nadh:furfural
    35% identity, 94% coverage of query (180 bits)

3s2fA Crystal structure of furx nadh:furfural
    35% identity, 94% coverage of query (180 bits)

3s2eE Crystal structure of furx nadh complex 1
    35% identity, 94% coverage of query (180 bits)

RR42_RS34260 Alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus basilensis FW507-4G11
    36% identity, 94% coverage of query (178 bits)

ADHA_SYNY3 / P74721 Aldehyde reductase AdhA; Alcohol dehydrogenase AdhA; EC 1.1.1.2 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 3 papers)
P74721 alcohol dehydrogenase (EC 1.1.1.1) from Synechocystis sp. PCC 6803 (see paper)
    31% identity, 99% coverage of query (176 bits)

adhA / C0SPA5 S-(hydroxymethyl)bacillithiol dehydrogenase (EC 1.1.1.306) from Bacillus subtilis (strain 168) (see 2 papers)
ADHA_BACSU / C0SPA5 Probable formaldehyde dehydrogenase AdhA; EC 1.1.1.- from Bacillus subtilis (strain 168) (see paper)
    33% identity, 90% coverage of query (174 bits)

6n7lC / A0A077EGR8 Crystal structure of an alcohol dehydrogenase from elizabethkingia anophelis nuhp1
    34% identity, 94% coverage of query (174 bits)

Q8L3C9 alcohol dehydrogenase (EC 1.1.1.1) from Flavobacterium frigidimaris (see paper)
    34% identity, 98% coverage of query (173 bits)

1lluA / Q9HTD9 The ternary complex of pseudomonas aeruginosa alcohol dehydrogenase with its coenzyme and weak substrate (see paper)
    35% identity, 98% coverage of query (172 bits)

A1R6C3 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Paenarthrobacter aurescens (see paper)
    33% identity, 98% coverage of query (172 bits)

3meqA / A0A0H3G9R2 Crystal structure of alcohol dehydrogenase from brucella melitensis
    34% identity, 97% coverage of query (168 bits)

A0A125SUY5 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mycobacterium sp. (see paper)
    31% identity, 89% coverage of query (164 bits)

ADHC1_MYCS2 / P0CH36 NADP-dependent alcohol dehydrogenase C 1; Ms-ADHC 1; EC 1.1.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
ADHC2_MYCS2 / P0CH37 NADP-dependent alcohol dehydrogenase C 2; Ms-ADHC 2; EC 1.1.1.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
    32% identity, 89% coverage of query (163 bits)

GEDH1 / Q2KNL6 geraniol dehydrogenase (EC 1.1.1.183) from Ocimum basilicum (see paper)
GEDH1_OCIBA / Q2KNL6 Geraniol dehydrogenase 1; ObaGEDH1; EC 1.1.1.183 from Ocimum basilicum (Sweet basil) (see paper)
Q2KNL6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Ocimum basilicum (see paper)
    33% identity, 92% coverage of query (161 bits)

V9SCJ1 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    32% identity, 95% coverage of query (161 bits)

A0A023RBJ1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    33% identity, 91% coverage of query (161 bits)

P9WQC5 NADP-dependent alcohol dehydrogenase C; EC 1.1.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    31% identity, 97% coverage of query (161 bits)

A1IIA3 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    31% identity, 95% coverage of query (160 bits)

6z42A / E1V3M3 The low resolution structure of a zinc-dependent alcohol dehydrogenase from halomonas elongata.
    35% identity, 94% coverage of query (157 bits)

Q1HGA8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Linum usitatissimum (see 3 papers)
    31% identity, 89% coverage of query (156 bits)

ADH2 / GB|CAA21988.1 alcohol dehydrogenase 2; EC 1.1.1.1 from Candida albicans (see paper)
    32% identity, 95% coverage of query (156 bits)

5z0cA / J7JYU1 Nerol dehydrogenase from persicaria minor (see paper)
    33% identity, 90% coverage of query (156 bits)

T1WW77 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    32% identity, 94% coverage of query (155 bits)

B6UQD0 alcohol dehydrogenase (EC 1.1.1.1) from Saccharomyces pastorianus (see 2 papers)
    33% identity, 95% coverage of query (155 bits)

G3FFC9 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    32% identity, 95% coverage of query (155 bits)

W6CX26 alcohol dehydrogenase (EC 1.1.1.1); aryl-alcohol dehydrogenase (EC 1.1.1.90); aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Yokenella sp. (see paper)
    34% identity, 93% coverage of query (154 bits)

6c49A / A0A1E3MC83 Crystal structure of alcohol dehydrogenase from acinetobacter baumannii
    33% identity, 91% coverage of query (152 bits)

Ahr / b4269 NADPH-dependent aldehyde reductase Ahr (EC 1.1.1.2) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ahr / P27250 NADPH-dependent aldehyde reductase Ahr (EC 1.1.1.2) from Escherichia coli (strain K12) (see 11 papers)
AHR_ECOLI / P27250 Aldehyde reductase Ahr; Zinc-dependent alcohol dehydrogenase Ahr; EC 1.1.1.2 from Escherichia coli (strain K12) (see 3 papers)
P27250 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Escherichia coli (see paper)
    33% identity, 97% coverage of query (152 bits)

Q9CEN0 alcohol dehydrogenase (EC 1.1.1.1) from Lactococcus lactis subsp. lactis (see paper)
    30% identity, 95% coverage of query (152 bits)

7bu2B / P27250 Structure of alcohol dehydrogenase yjgb from escherichia coli (see paper)
    33% identity, 97% coverage of query (152 bits)

5envA / P00330 Yeast alcohol dehydrogenase with bound coenzyme (see paper)
    32% identity, 95% coverage of query (152 bits)

ADH1 / P00330 alcohol dehydrogenase 1 (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH1_YEAST / P00330 Alcohol dehydrogenase 1; Alcohol dehydrogenase I; ADHI; NADH-dependent methylglyoxal reductase; YADH-1; EC 1.1.1.1; EC 1.1.1.54; EC 1.1.1.78 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 12 papers)
    32% identity, 95% coverage of query (152 bits)

7bu3A Structure of alcohol dehydrogenase yjgb in complex with NADP from escherichia coli
    33% identity, 97% coverage of query (152 bits)

4w6zA Yeast alcohol dehydrogenase i, saccharomyces cerevisiae fermentative enzyme
    32% identity, 95% coverage of query (152 bits)

4eezB / D2BLA0 Crystal structure of lactococcus lactis alcohol dehydrogenase variant re1 (see paper)
    31% identity, 95% coverage of query (151 bits)

T1WWB9 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    32% identity, 91% coverage of query (151 bits)

B5AR58 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Leucaena leucocephala (see paper)
    31% identity, 89% coverage of query (151 bits)

ADH2 / P00331 alcohol dehydrogenase II (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH2_YEAST / P00331 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADHII; YADH-2; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
    33% identity, 95% coverage of query (150 bits)

CADH6_ARATH / O65621 Probable cinnamyl alcohol dehydrogenase 6; AtCAD6; Cinnamyl alcohol dehydrogenase-like protein A; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    31% identity, 90% coverage of query (149 bits)

B5TR18 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Leucaena leucocephala (see paper)
    31% identity, 89% coverage of query (149 bits)

Q9ATW1 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Fragaria x ananassa (see paper)
    32% identity, 95% coverage of query (147 bits)

F6L7F5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Camellia sinensis (see paper)
    30% identity, 95% coverage of query (147 bits)

adhA / Q8NLX9 Zn2+-dependent alcohol dehydrogenase (EC 1.1.1.1; EC 1.1.1.244) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 5 papers)
    31% identity, 92% coverage of query (146 bits)

K9S1J6 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens (see paper)
    30% identity, 92% coverage of query (145 bits)

alrA / BAB12270.1 NADP-dependent alcohol dehydrogenase from Acinetobacter sp. M-1 (see paper)
    33% identity, 89% coverage of query (145 bits)

K9S0X0 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens var. hirtella (see paper)
    30% identity, 92% coverage of query (145 bits)

Build an alignment

Build an alignment for N515DRAFT_0878 and 59 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

D0ITF8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Helicobacter pylori (see paper)
3twoB The crystal structure of cad from helicobacter pylori complexed with NADP(h) (see paper)
    29% identity, 93% coverage of query (144 bits)

CADH3_ARATH / Q9SJ10 Cinnamyl alcohol dehydrogenase 3; AtCAD3; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    30% identity, 100% coverage of query (144 bits)

CAD7 / Q02971 cinnamyl alcohol dehydrogenase 7 (EC 1.1.1.195) from Arabidopsis thaliana (see 2 papers)
CADH7_ARATH / Q02971 Cinnamyl alcohol dehydrogenase 7; AtCAD7; Cinnamyl alcohol dehydrogenase-like protein B; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    30% identity, 96% coverage of query (143 bits)

T1WWR8 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    31% identity, 94% coverage of query (143 bits)

CAD1_MEDTR / A0A072VPZ8 Cinnamyl alcohol dehydrogenase 1; Mt-CAD1; Coniferol dehydrogenase; Coumaroyl alcohol dehydrogenase; Sinapyl alcohol dehydrogenase; EC 1.1.1.195 from Medicago truncatula (Barrel medic) (Medicago tribuloides) (see paper)
    31% identity, 90% coverage of query (143 bits)

ADH3 / P07246 alcohol dehydrogenase III (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH3_YEAST / P07246 Alcohol dehydrogenase 3, mitochondrial; Alcohol dehydrogenase III; ADHIII; YADH-3; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
    30% identity, 95% coverage of query (142 bits)

CADH2_ARATH / Q9SJ25 Cinnamyl alcohol dehydrogenase 2; AtCAD2; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    30% identity, 100% coverage of query (142 bits)

K9RZL7 geraniol dehydrogenase (NADP+) (EC 1.1.1.183) from Perilla frutescens var. hirtella (see paper)
    30% identity, 92% coverage of query (142 bits)

Q7XWU3 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Oryza sativa Japonica Group (see paper)
    30% identity, 90% coverage of query (141 bits)

MTD / Q38707 mannitol dehydrogenase (EC 1.1.1.255) from Apium graveolens (see paper)
Q38707 mannitol dehydrogenase (EC 1.1.1.255) from Apium graveolens (see paper)
    30% identity, 91% coverage of query (141 bits)

CADH9_ARATH / P42734 Probable cinnamyl alcohol dehydrogenase 9; AtCAD9; EC 1.1.1.195 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    30% identity, 92% coverage of query (141 bits)

cad / O25732 cinnamyl-alcohol dehydrogenase (EC 1.1.1.2; EC 1.1.1.95; EC 1.1.1.195) from Helicobacter pylori (strain ATCC 700392 / 26695) (see 3 papers)
    29% identity, 93% coverage of query (140 bits)

ADH5 / P38113 alcohol dehydrogenase V (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
ADH5_YEAST / P38113 Alcohol dehydrogenase 5; Alcohol dehydrogenase V; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    31% identity, 95% coverage of query (140 bits)

E3UTQ9 allyl-alcohol dehydrogenase (EC 1.1.1.54) from Fusarium oxysporum (see paper)
    30% identity, 94% coverage of query (139 bits)

G3DSC5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Liriodendron tulipifera (see paper)
    31% identity, 91% coverage of query (139 bits)

5vktA / C5XC49 Cinnamyl alcohol dehydrogenases (sbcad4) from sorghum bicolor (l.) Moench (see paper)
    31% identity, 94% coverage of query (138 bits)

C5XC49 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Sorghum bicolor (see 2 papers)
    31% identity, 94% coverage of query (138 bits)

A0A1D6BJ11 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Triticum aestivum (see paper)
    30% identity, 90% coverage of query (137 bits)

Q8H0L8 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Solanum tuberosum (see paper)
    33% identity, 94% coverage of query (137 bits)

T1WVG5 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    31% identity, 90% coverage of query (136 bits)

T1WUT6 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    29% identity, 89% coverage of query (136 bits)

7cguA / A0A8A5L0G9 Crystal structure of abhar
    31% identity, 99% coverage of query (136 bits)

A1IIA4 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus (see paper)
    30% identity, 95% coverage of query (135 bits)

T1WUU2 cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) from Populus tomentosa (see paper)
    30% identity, 89% coverage of query (135 bits)

H9ZGN0 alcohol dehydrogenase (EC 1.1.1.1) from Ogataea angusta (see paper)
    29% identity, 95% coverage of query (135 bits)

T3R_CATRO / A0A161CAI1 16-methoxy-2,3-dihydro-3-hydroxytabersonine synthase; 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase; Alcohol dehydrogenase-like protein 1; ADHL1; Tabersonine 3-reductase; EC 1.1.99.41 from Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) (see 2 papers)
A0A161CAI1 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase (EC 1.1.99.41) from Catharanthus roseus (see 2 papers)
    27% identity, 90% coverage of query (134 bits)

SAD / Q94G59 sinapyl alcohol dehydrogenase (EC 1.1.1.195) from Populus tremuloides (see paper)
    30% identity, 89% coverage of query (134 bits)

Q9P6C8 alcohol dehydrogenase (EC 1.1.1.1) from Neurospora crassa (see paper)
    31% identity, 93% coverage of query (134 bits)

5k1sA / Q1D4I2 Crystal structure of aibc (see paper)
    32% identity, 94% coverage of query (134 bits)

1yqdA / Q94G59 Sinapyl alcohol dehydrogenase complexed with NADP+ (see paper)
    30% identity, 90% coverage of query (133 bits)

6k3gB / Q6V4H0 Crystal structure of 10-hydroxygeraniol dehydrogenase from cantharanthus roseus in complex with NADP+ (see paper)
    32% identity, 89% coverage of query (129 bits)

ADH6_YEAST / Q04894 NADP-dependent alcohol dehydrogenase 6; NADP-dependent alcohol dehydrogenase VI; ScADHVI; EC 1.1.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
1piwA / Q04894 Apo and holo structures of an NADP(h)-dependent cinnamyl alcohol dehydrogenase from saccharomyces cerevisiae (see paper)
    31% identity, 91% coverage of query (127 bits)

YddN / b1478 ethanol dehydrogenase / alcohol dehydrogenase (EC 1.1.1.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
adhP / P39451 ethanol dehydrogenase / alcohol dehydrogenase (EC 1.1.1.1) from Escherichia coli (strain K12) (see 5 papers)
4gkvB / P39451 Structure of escherichia coli adhp (ethanol-inducible dehydrogenase) with bound NAD (see paper)
    31% identity, 91% coverage of query (125 bits)

5yatA / C4R0S8 Crystal structure of mitochondrial alcohol dehydrogenase isozyme iii from komagataella phaffii gs115 (see paper)
    30% identity, 95% coverage of query (123 bits)

5h83A / A0A1C7D195 Heteroyohimbine synthase hys from catharanthus roseus - apo form (see paper)
    30% identity, 90% coverage of query (122 bits)

1uufA / P75691 Crystal structure of a zinc-type alcohol dehydrogenase-like protein yahk
    33% identity, 92% coverage of query (122 bits)

8b1vA Dihydroprecondylocarpine acetate synthase 2 from tabernanthe iboga
    28% identity, 92% coverage of query (120 bits)

8b25B / A0A5B8X8Z0 Dihydroprecondylocarpine acetate synthase 2 from tabernanthe iboga - stemmadenine acetate bound structure (see paper)
    28% identity, 92% coverage of query (120 bits)

8a3nB / W8JWW7 Geissoschizine synthase from catharanthus roseus - binary complex with NADP+ (see paper)
    26% identity, 95% coverage of query (120 bits)

7c2oA / M4VRJ6 Crystal structure of the r-specific carbonyl reductase from candida parapsilosis atcc 7330 without dtt
    28% identity, 93% coverage of query (119 bits)

5h81B / A0A1C7D193 Heteroyohimbine synthase thas2 from catharanthus roseus - complex with NADP+ (see paper)
    27% identity, 90% coverage of query (118 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory