Searching for up to 100 curated homologs for N515DRAFT_1217 FitnessBrowser__Dyella79:N515DRAFT_1217 (468 a.a.)
Found high-coverage hits (≥70%) to 66 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DVU0030 / VIMSS8508254 DVU0030 regulator of Amino acid transport from Desulfovibrio salexigens DSM 2638
38% identity, 99% coverage of query (355 bits)
DVU0030 / VIMSS8501445 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris str. Miyazaki F
41% identity, 99% coverage of query (343 bits)
DVU0030 / VIMSS7454265 DVU0030 regulator of Amino acid transport from Desulfohalobium retbaense DSM 5692
39% identity, 98% coverage of query (331 bits)
DVU0030 / VIMSS7650531 DVU0030 regulator of Amino acid transport from Desulfovibrio magneticus RS-1
42% identity, 96% coverage of query (329 bits)
DVU0030 / VIMSS408289 DVU0030 regulator of Amino acid transport from Desulfovibrio vulgaris Hildenborough
41% identity, 98% coverage of query (324 bits)
YjiR / b4340 fused putative DNA-binding transcriptional regulator/putative aminotransferase YjiR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yjiR / RF|NP_418760 uncharacterized HTH-type transcriptional regulator yjiR from Escherichia coli K12 (see 2 papers)
38% identity, 100% coverage of query (323 bits)
YdcR / b1439 fused putative DNA-binding transcriptional regulator/putative aminotransferase YdcR from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydcR / MB|P77730 uncharacterized HTH-type transcriptional regulator ydcR from Escherichia coli K12 (see 3 papers)
41% identity, 100% coverage of query (320 bits)
DVU0030 / VIMSS7533539 DVU0030 regulator of Amino acid transport from Desulfomicrobium baculatum DSM 4028
39% identity, 99% coverage of query (310 bits)
DVU0030 / VIMSS393253 DVU0030 regulator of Amino acid transport from Desulfovibrio desulfuricans G20
37% identity, 94% coverage of query (298 bits)
Build an alignment for N515DRAFT_1217 and 9 homologs with ≥ 30% identity
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3aovA / O57946 Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with plp
26% identity, 80% coverage of query (192 bits)
3wx9A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, gla, 4ad, 2og, glu and kya
26% identity, 80% coverage of query (192 bits)
3av7A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, kyn as substrates and kya as products
26% identity, 80% coverage of query (192 bits)
3aowC Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with akg
26% identity, 80% coverage of query (192 bits)
O57946 kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Pyrococcus horikoshii (see paper)
26% identity, 80% coverage of query (191 bits)
ARAT1_THELN / H3ZPL1 Aromatic-amino-acid aminotransferase 1; ARAT-I; AROAT; EC 2.6.1.57 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see paper)
28% identity, 80% coverage of query (190 bits)
A0A060PQX5 branched-chain-amino-acid transaminase (EC 2.6.1.42) from Thermococcus sp. (see paper)
29% identity, 80% coverage of query (187 bits)
YdfD/YisV / VIMSS6924547 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Paenibacillus sp. JDR-2
29% identity, 99% coverage of query (187 bits)
AZOBR_RS06555 Branched-chain-amino-acid transaminase (EC 2.6.1.42) from Azospirillum brasilense Sp245
30% identity, 79% coverage of query (182 bits)
Ac3H11_1015 Aromatic-amino-acid aminotransferase (EC 2.6.1.57) from Acidovorax sp. GW101-3H11
29% identity, 80% coverage of query (182 bits)
LYSN_THET2 / Q72LL6 2-aminoadipate transaminase; 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT; EC 2.6.1.39 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 3 papers)
Q72LL6 2-aminoadipate transaminase (EC 2.6.1.39) from Thermus thermophilus (see paper)
2zyjA / Q72LL6 Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-glutamate), from thermus thermophilus hb27 (see paper)
32% identity, 81% coverage of query (179 bits)
lysN / Q5SL82 L-2-aminoadipate aminotransferase monomer (EC 2.6.1.39) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
32% identity, 81% coverage of query (179 bits)
3cbfA Crystal structure of lysn, alpha-aminoadipate aminotransferase, from thermus thermophilus hb27
32% identity, 81% coverage of query (179 bits)
2egyA Crystal structure of lysn, alpha-aminoadipate aminotransferase (substrate free form), from thermus thermophilus hb27
32% identity, 81% coverage of query (179 bits)
2z1yA Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-leucine), from thermus thermophilus hb27
33% identity, 76% coverage of query (171 bits)
YdfD/YisV / VIMSS822665 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus clausii KSM-K16
27% identity, 98% coverage of query (166 bits)
BWI76_RS24235 Branched-chain-amino-acid transaminase (EC 2.6.1.42) from Klebsiella michiganensis M5al
29% identity, 77% coverage of query (161 bits)
1wstA / Q9V2W5 Crystal structure of multiple substrate aminotransferase (msat) from thermococcus profundus
27% identity, 80% coverage of query (161 bits)
YdfD/YisV / VIMSS63013 YdfD/YisV regulator of Metabolite transport (activator/repressor) from Bacillus halodurans C-125
28% identity, 100% coverage of query (161 bits)
NORG_STAA8 / Q2G1P1 HTH-type transcriptional regulator NorG from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
24% identity, 94% coverage of query (160 bits)
2zc0A / Q9C4M4 Crystal structure of an archaeal alanine:glyoxylate aminotransferase (see paper)
29% identity, 78% coverage of query (158 bits)
Ac3H11_1358 L-leucine transaminase; L-isoleucine transaminase (EC 2.6.1.42) from Acidovorax sp. GW101-3H11
32% identity, 76% coverage of query (150 bits)
1vp4A / Q9X0L5 Crystal structure of a putative aminotransferase (tm1131) from thermotoga maritima msb8 at 1.82 a resolution
26% identity, 82% coverage of query (148 bits)
PdxR / VIMSS10395811 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus gallolyticus UCN34
26% identity, 81% coverage of query (126 bits)
PdxR / VIMSS5804477 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus equi subsp. zooepidemicus MGCS10565
24% identity, 90% coverage of query (122 bits)
7zlaB / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the half-closed conformation (see paper)
29% identity, 89% coverage of query (118 bits)
8tn3A / Q643B9 Structure of s. Hygroscopicus aminotransferase mppq complexed with pyridoxamine 5'-phosphate (pmp) (see paper)
31% identity, 78% coverage of query (117 bits)
PdxR / VIMSS101492 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus pyogenes M1 GAS
26% identity, 82% coverage of query (116 bits)
PdxR / VIMSS3789276 PdxR regulator of Pyridoxine biosynthesis, effector Pyridoxal-5-phosphate from Streptococcus gordonii str. Challis substr. CH1
26% identity, 80% coverage of query (116 bits)
AADAT_MOUSE / Q9WVM8 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Mus musculus (Mouse) (see paper)
Q9WVM8 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Mus musculus (see paper)
26% identity, 79% coverage of query (114 bits)
7zn5B / Q5WKW3 Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the closed conformation, c2 symmetry. (see paper)
28% identity, 89% coverage of query (112 bits)
Aadat / Q64602 α-aminoadipate aminotransferase subunit (EC 2.6.1.39) from Rattus norvegicus (see paper)
AADAT_RAT / Q64602 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Rattus norvegicus (Rat) (see paper)
Q64602 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Rattus norvegicus (see 2 papers)
26% identity, 79% coverage of query (105 bits)
ATTY_CAEEL / Q93703 Tyrosine aminotransferase; TAT; L-tyrosine:2-oxoglutarate aminotransferase; EC 2.6.1.5 from Caenorhabditis elegans (see 3 papers)
25% identity, 78% coverage of query (100 bits)
HPGT_AMYOR / O52815 (S)-3,5-dihydroxyphenylglycine transaminase; p-hydroxyphenylglycine transaminase; EC 2.6.1.103 from Amycolatopsis orientalis (Nocardia orientalis) (see 2 papers)
28% identity, 71% coverage of query (99.0 bits)
4gdyB / Q8N5Z0 Kynurenine aminotransferase ii inhibitors
24% identity, 82% coverage of query (98.6 bits)
4gebA Kynurenine aminotransferase ii inhibitors
24% identity, 82% coverage of query (98.6 bits)
4ge9A Kynurenine aminotransferase ii inhibitors
24% identity, 82% coverage of query (98.6 bits)
4ge7A Kynurenine aminotransferase ii inhibitors
24% identity, 82% coverage of query (98.6 bits)
A0A1D8PPA8 aromatic-amino-acid transaminase (EC 2.6.1.57) from Candida albicans (see paper)
26% identity, 77% coverage of query (97.8 bits)
AADAT / Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (EC 2.6.1.7; EC 2.6.1.39) from Homo sapiens (see 5 papers)
AADAT_HUMAN / Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; KAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; Alpha-aminoadipate aminotransferase; AadAT; Glycine transaminase AADAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Methionine--glyoxylate transaminase AADAT; EC 2.6.1.39; EC 2.6.1.4; EC 2.6.1.63; EC 2.6.1.7; EC 2.6.1.73 from Homo sapiens (Human) (see 4 papers)
Q8N5Z0 2-aminoadipate transaminase (EC 2.6.1.39); kynurenine-oxoglutarate transaminase (EC 2.6.1.7) from Homo sapiens (see 16 papers)
24% identity, 82% coverage of query (97.8 bits)
6t8qA Hkatii in complex with ligand (2r)-n-benzyl-1-[6-methyl-5-(oxan-4-yl)- 7-oxo-6h,7h-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2- carboxamide
24% identity, 82% coverage of query (97.8 bits)
5tf5A Crystal structure of human kat-2 in complex with a reversible inhibitor
24% identity, 82% coverage of query (97.8 bits)
2r2nA The crystal structure of human kynurenine aminotransferase ii in complex with kynurenine
24% identity, 82% coverage of query (97.8 bits)
4ge4A Kynurenine aminotransferase ii inhibitors
23% identity, 82% coverage of query (97.8 bits)
3ue8A Kynurenine aminotransferase ii inhibitors
24% identity, 76% coverage of query (94.4 bits)
2vgzA Crystal structure of human kynurenine aminotransferase ii
24% identity, 78% coverage of query (94.4 bits)
2xh1A Crystal structure of human kat ii-inhibitor complex
24% identity, 78% coverage of query (94.0 bits)
1o4sB / Q9X0Y2 Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
24% identity, 72% coverage of query (79.7 bits)
6l1nA Substrate bound bacf structure from bacillus subtillis
24% identity, 74% coverage of query (78.6 bits)
1gdeA Crystal structure of pyrococcus protein a-1 e-form
24% identity, 82% coverage of query (76.6 bits)
1gd9A / O59096 Crystall structure of pyrococcus protein-a1 (see paper)
24% identity, 82% coverage of query (76.6 bits)
mfnC / Q58097 2-furaldehyde phosphate aminotransferase (EC 2.6.1.108) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
MFNC_METJA / Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase; 4-HFC-P:alanine aminotransferase; EC 2.6.1.108 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase (EC 2.6.1.108) from Methanocaldococcus jannaschii (see paper)
21% identity, 79% coverage of query (75.1 bits)
P14909 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
23% identity, 70% coverage of query (69.7 bits)
MalY / b1622 negative regulator of MalT activity/cystathionine β-lyase (EC 4.4.1.13; EC 4.4.1.1; EC 4.4.1.28; EC 5.1.1.1) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
malY / P23256 negative regulator of MalT activity/cystathionine β-lyase (EC 4.4.1.13; EC 4.4.1.1; EC 5.1.1.10) from Escherichia coli (strain K12) (see 18 papers)
MALY_ECOLI / P23256 Protein MalY; EC 4.4.1.13 from Escherichia coli (strain K12) (see 2 papers)
8bobA / P23256 Structural basis for negative regulation of the maltose system (see paper)
malY maltose regulon modulator MalY; EC 4.4.1.8 from Escherichia coli K12 (see 6 papers)
24% identity, 78% coverage of query (68.2 bits)
7dlwB / Q9STR4 Crystal structure of arabidopsis acs7 in complex with ppg (see paper)
25% identity, 74% coverage of query (66.6 bits)
ISS1 / Q9C969 aromatic aminotransferase ISS1 (EC 2.6.1.27) from Arabidopsis thaliana (see paper)
ISS1_ARATH / Q9C969 Aromatic aminotransferase ISS1; Methionine aminotransferase ISS1; Phenylalanine aminotransferase ISS1; Protein INDOLE SEVERE SENSITIVE 1; Protein REVERSAL OF SAV3 PHENOTYPE 1; Tryptophan aminotransferase ISS1; Tyrosine aminotransferase ISS1; EC 2.6.1.27; EC 2.6.1.5; EC 2.6.1.88 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9C969 aromatic-amino-acid transaminase (EC 2.6.1.57) from Arabidopsis thaliana (see paper)
26% identity, 70% coverage of query (64.3 bits)
6s8wB / Q4X0F7 Aromatic aminotransferase aroh (aro8) form aspergillus fumigatus in complex with plp (internal aldimine)
22% identity, 70% coverage of query (62.0 bits)
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Lawrence Berkeley National Laboratory