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Searching for up to 100 curated homologs for N515DRAFT_1251 FitnessBrowser__Dyella79:N515DRAFT_1251 (442 a.a.)

Found high-coverage hits (≥70%) to 73 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

fucD / Q8P3K2 L-fuconate dehydratase monomer (EC 4.2.1.68) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
FUCD_XANCP / Q8P3K2 L-fuconate dehydratase; FucD; EC 4.2.1.68 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
    76% identity, 98% coverage of query (663 bits)

1yeyC / Q8P3K2 Crystal structure of l-fuconate dehydratase from xanthomonas campestris pv. Campestris str. Atcc 33913
    76% identity, 97% coverage of query (661 bits)

2hxtA Crystal structure of l-fuconate dehydratase from xanthomonas campestris liganded with mg++ and d-erythronohydroxamate
    76% identity, 97% coverage of query (660 bits)

2hxuA Crystal structure of k220a mutant of l-fuconate dehydratase from xanthomonas campestris liganded with mg++ and l-fuconate
    76% identity, 97% coverage of query (657 bits)

HSERO_RS05235 L-fuconate dehydratase (EC 4.2.1.68) from Herbaspirillum seropedicae SmR1
    57% identity, 95% coverage of query (509 bits)

4ip4A / Q1GLV3 Crystal structure of l-fuconate dehydratase from silicibacter sp. Tm1040 liganded with mg
    58% identity, 95% coverage of query (505 bits)

4ip5A Crystal structure of l-fuconate dehydratase from silicibacter sp. Tm1040 liganded with mg and d-erythronohydroxamate
    58% identity, 95% coverage of query (505 bits)

4a35A / Q7L5Y1 Crystal structure of human mitochondrial enolase superfamily member 1 (enosf1) (see paper)
    49% identity, 97% coverage of query (472 bits)

ENOF1_HUMAN / Q7L5Y1 Mitochondrial enolase superfamily member 1; Antisense RNA to thymidylate synthase; rTS; L-fuconate dehydratase; EC 4.2.1.68 from Homo sapiens (Human) (see 4 papers)
    49% identity, 97% coverage of query (472 bits)

G3Y683 L-fuconate dehydratase (EC 4.2.1.68) from Aspergillus niger (see paper)
    52% identity, 97% coverage of query (458 bits)

LGD1 / Q0QWS4 L-galactonate dehydratase (EC 4.2.1.146) from Hypocrea jecorina (see paper)
LGD1_HYPJE / Q0QWS4 L-galactonate dehydratase; EC 4.2.1.146 from Hypocrea jecorina (Trichoderma reesei) (see paper)
Q0QWS4 L-galactonate dehydratase (EC 4.2.1.146) from Trichoderma reesei (see 2 papers)
    52% identity, 96% coverage of query (445 bits)

Build an alignment

Build an alignment for N515DRAFT_1251 and 11 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

4h19A / Q7CU39 Crystal structure of an enolase (mandelate racemase subgroup, target efi-502087) from agrobacterium tumefaciens, with bound mg and d- ribonohydroxamate, ordered loop
    28% identity, 95% coverage of query (154 bits)

SM_b21107 dehydratase involved in L-fucose catabolism from Sinorhizobium meliloti 1021
    28% identity, 83% coverage of query (131 bits)

araD / Q97U96 D-arabinonate dehydratase subunit (EC 4.2.1.5) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
ARAD_SACS2 / Q97U96 Arabinonate dehydratase; EC 4.2.1.5 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q97U96 Arabinonate dehydratase (EC 4.2.1.5) from Saccharolobus solfataricus (see paper)
    28% identity, 85% coverage of query (111 bits)

2qq6B / Q1AYK7 Crystal structure of mandelate racemase/muconate lactonizing enzyme- like protein from rubrobacter xylanophilus dsm 9941
    28% identity, 74% coverage of query (108 bits)

SSO26655 / Q97VG1 D-xylonate dehydratase subunit (EC 4.2.1.25; EC 4.2.1.82) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
    25% identity, 82% coverage of query (90.9 bits)

aci / H2IFX0 3,6-anhydro-L-galactonate cycloisomerase (EC 5.5.1.25) from Vibrio sp. (strain EJY3) (see paper)
ACI_VIBSJ / H2IFX0 3,6-anhydro-alpha-L-galactonate cycloisomerase; AHGA cycloisomerase; EC 5.5.1.25 from Vibrio sp. (strain EJY3) (see paper)
H2IFX0 3,6-anhydro-L-galactonate cycloisomerase (EC 5.5.1.25) from Vibrio sp. (see paper)
    23% identity, 71% coverage of query (88.2 bits)

3toyA Crystal structure of enolase brado_4202 (target efi-501651) from bradyrhizobium sp. Ors278 with calcium and acetate bound
    26% identity, 74% coverage of query (85.1 bits)

IMAND_ENTBW / A8RQK7 D-galactonate dehydratase family member CLOBOL_02770 from Enterocloster bolteae (strain ATCC BAA-613 / DSM 15670 / CCUG 46953 / JCM 12243 / WAL 16351) (Clostridium bolteae) (see paper)
    22% identity, 88% coverage of query (81.3 bits)

GAD_THETE / Q704D2 D-gluconate dehydratase; EC 4.2.1.39 from Thermoproteus tenax (see 2 papers)
gad / CAF18462.1 gluconate dehydratase from Thermoproteus tenax (see paper)
    26% identity, 72% coverage of query (75.1 bits)

G4RJQ1 gluconate dehydratase (EC 4.2.1.39) from Thermoproteus tenax (see paper)
    26% identity, 72% coverage of query (75.1 bits)

3rcyF Crystal structure of mandelate racemase/muconate lactonizing enzyme- like protein from roseovarius sp. Tm1035
    23% identity, 90% coverage of query (74.3 bits)

IMAND_CATAD / C7PW26 D-galactonate dehydratase family member Caci_4410 from Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908) (see paper)
    24% identity, 86% coverage of query (72.8 bits)

4e6mA / Q8ZNH1 Crystal structure of putative dehydratase protein from salmonella enterica subsp. Enterica serovar typhimurium (salmonella typhimurium)
    21% identity, 95% coverage of query (72.4 bits)

GAD_SACS2 / Q97U27 D-gluconate/D-galactonate dehydratase; GAD; GNAD; EC 4.2.1.140; EC 4.2.1.39; EC 4.2.1.6 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
Q97U27 gluconate/galactonate dehydratase (EC 4.2.1.140) from Saccharolobus solfataricus (see paper)
    23% identity, 72% coverage of query (72.0 bits)

IMND2_ENTGE / C9A1P5 D-galactonate dehydratase family member EGBG_02030 from Enterococcus gallinarum (strain EG2) (see paper)
    23% identity, 88% coverage of query (71.6 bits)

4hcdA / Q7CSI0 Crystal structure of d-glucarate dehydratase from agrobacterium tumefaciens complexed with magnesium
    23% identity, 92% coverage of query (70.1 bits)

4hclA Crystal structure of d-glucarate dehydratase from agrobacterium tumefaciens complexed with magnesium and l-lyxarohydroxamate
    23% identity, 92% coverage of query (70.1 bits)

YidU / b4478 D-galactonate dehydratase (EC 4.2.1.140; EC 4.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
dgoD / Q6BF17 D-galactonate dehydratase (EC 4.2.1.140) from Escherichia coli (strain K12) (see 5 papers)
DGOD_ECOLI / Q6BF17 D-galactonate dehydratase; GalD; EC 4.2.1.6 from Escherichia coli (strain K12) (see 3 papers)
Q6BF17 galactonate dehydratase (EC 4.2.1.6) from Escherichia coli (see paper)
dgoD / RF|YP_026237 D-galactonate dehydratase; EC 4.2.1.6 from Escherichia coli K12 (see 6 papers)
    21% identity, 88% coverage of query (69.7 bits)

4mmwA Crystal structure of d-glucarate dehydratase from agrobacterium tumefaciens complexed with magnesium, l-xylarohydroxamate and l- lyxarohydroxamate
    23% identity, 92% coverage of query (69.7 bits)

3t6cA / D4GJ14 Crystal structure of an enolase from pantoea ananatis (efi target efi- 501676) with bound d-gluconate and mg
    24% identity, 88% coverage of query (67.0 bits)

DGD_PANAM / D4GJ14 D-galactonate dehydratase family member RspA; D-gluconate dehydratase; Starvation sensing protein RspA homolog; EC 4.2.1.-; EC 4.2.1.39 from Pantoea ananatis (strain LMG 20103) (see paper)
    24% identity, 88% coverage of query (67.0 bits)

IMAND_CLOB8 / A6M2W4 D-galactonate dehydratase family member Cbei_4837 from Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) (see paper)
    21% identity, 90% coverage of query (65.1 bits)

3gy1B / A6M2W4 Crystal structure of putative mandelate racemase/muconate lactonizing protein from clostridium beijerinckii ncimb 8052
    22% identity, 91% coverage of query (65.1 bits)

DMGD_MUSP7 / C6CBG9 D-galactonate dehydratase family member Dd703_0947; D-gluconate dehydratase; D-mannonate dehydratase; EC 4.2.1.-; EC 4.2.1.39; EC 4.2.1.8 from Musicola paradisiaca (strain Ech703) (Dickeya paradisiaca) (Dickeya dadantii) (see paper)
    25% identity, 89% coverage of query (63.5 bits)

3tjiA / A4W7D6 Crystal structure of an enolase from enterobacter sp. 638 (efi target efi-501662) with bound mg
    22% identity, 90% coverage of query (62.8 bits)

A4W7D6 D-galactonate dehydratase family member Ent638_0932 from Enterobacter sp. (strain 638)
    22% identity, 90% coverage of query (62.8 bits)

IMND1_VIBCR / C9NUM5 D-galactonate dehydratase family member VIC002985 from Vibrio coralliilyticus (strain ATCC BAA-450 / DSM 19607 / CCUG 48437 / LMG 20984 / YB1) (see paper)
    22% identity, 73% coverage of query (62.4 bits)

2o56A / Q8ZKY6 Crystal structure of a member of the enolase superfamily from salmonella typhimurium
    22% identity, 85% coverage of query (62.0 bits)

DGD_SALEP / B5R541 D-galactonate dehydratase family member SEN1436; D-gluconate dehydratase; EC 4.2.1.-; EC 4.2.1.39 from Salmonella enteritidis PT4 (strain P125109) (see paper)
    23% identity, 89% coverage of query (61.6 bits)

3twbC / B5R541 Crystal structure of gluconate dehydratase (target efi-501679) from salmonella enterica subsp. Enterica serovar enteritidis str. P125109 complexed with magnesium and gluconic acid
    23% identity, 89% coverage of query (61.6 bits)

DGD_SALVI / B5QBD4 D-galactonate dehydratase family member SeV_A0456; D-gluconate dehydratase; EC 4.2.1.-; EC 4.2.1.39 from Salmonella virchow (see paper)
    23% identity, 89% coverage of query (61.6 bits)

4girB / D0X4R4 Crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, ethylene glycol and sulfate bound (ordered loops, space group p41212)
    22% identity, 73% coverage of query (60.5 bits)

IMND2_VIBCY / A6AMN2 D-galactonate dehydratase family member A1Q3065 from Vibrio campbellii (strain HY01) (see paper)
    22% identity, 73% coverage of query (60.5 bits)

IMAND_VIBH1 / D0X4R4 D-galactonate dehydratase family member VME_00770 from Vibrio harveyi (strain 1DA3) (see paper)
    22% identity, 73% coverage of query (60.5 bits)

DGD_STRBB / D7BPX0 D-galactonate dehydratase family member SBI_01856; D-gluconate dehydratase; EC 4.2.1.-; EC 4.2.1.39 from Streptomyces bingchenggensis (strain BCW-1) (see paper)
    25% identity, 88% coverage of query (60.5 bits)

MAND_CELJU / B3PDB1 D-galactonate dehydratase family member RspA; D-mannonate dehydratase; Starvation sensing protein RspA homolog; EC 4.2.1.-; EC 4.2.1.8 from Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) (see paper)
    22% identity, 87% coverage of query (59.3 bits)

4ihcB / C6CBG9 Crystal structure of probable mannonate dehydratase dd703_0947 (target efi-502222) from dickeya dadantii ech703
    24% identity, 89% coverage of query (58.9 bits)

3v3wA / B3PDB1 Crystal structure of an enolase from the soil bacterium cellvibrio japonicus (target efi-502161) with bound mg and glycerol
    22% identity, 87% coverage of query (58.5 bits)

MAND_ENT38 / A4WA78 D-galactonate dehydratase family member Ent638_1932; D-mannonate dehydratase; EC 4.2.1.-; EC 4.2.1.8 from Enterobacter sp. (strain 638) (see paper)
    23% identity, 88% coverage of query (58.2 bits)

MAND_STRS3 / D9UNB2 D-galactonate dehydratase family member SSLG_02014; D-mannonate dehydratase; EC 4.2.1.-; EC 4.2.1.8 from Streptomyces sp. (strain SPB78) (see paper)
    23% identity, 88% coverage of query (58.2 bits)

IMAND_STRSH / B5GCP6 D-galactonate dehydratase family member SSBG_02010 from Streptomyces sp. (strain SPB074) (see paper)
    23% identity, 88% coverage of query (56.2 bits)

IMAND_PECPW / D0KC90 D-galactonate dehydratase family member Pecwa_4254 from Pectobacterium parmentieri (strain WPP163) (Pectobacterium wasabiae (strain WPP163)) (see paper)
    22% identity, 73% coverage of query (55.1 bits)

3sbfA Crystal structure of the mutant p311a of enolase superfamily member from vibrionales bacterium complexed with mg and d-arabinonate
    21% identity, 73% coverage of query (54.7 bits)

IMAND_VIBBS / A5KUH4 D-galactonate dehydratase family member VSWAT3_13707 from Vibrionales bacterium (strain SWAT-3) (see paper)
    21% identity, 73% coverage of query (54.7 bits)

IMAND_PSECP / B8HCK2 D-galactonate dehydratase family member Achl_0790 from Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6) (Arthrobacter chlorophenolicus) (see paper)
    22% identity, 71% coverage of query (54.3 bits)

3r25B / A5KUH4 Crystal structure of enolase superfamily member from vibrionales bacterium complexed with mg and glycerol in the active site
    21% identity, 73% coverage of query (54.3 bits)

IMAND_ENTCS / C9CN91 D-galactonate dehydratase family member ECAG_02205 from Enterococcus casseliflavus (strain EC10) (see paper)
    20% identity, 73% coverage of query (53.1 bits)

IMND1_ENTGE / C8ZZN2 D-galactonate dehydratase family member EGBG_01401 from Enterococcus gallinarum (strain EG2) (see paper)
    19% identity, 73% coverage of query (52.0 bits)

4hnlA / C8ZZN2 Crystal structure of enolase egbg_01401 (target efi-502226) from enterococcus gallinarum eg2
    19% identity, 73% coverage of query (52.0 bits)

IMAND_PECAS / Q6DAR4 D-galactonate dehydratase family member ECA0189 from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) (see paper)
    22% identity, 73% coverage of query (52.0 bits)

4kwsA / Q1QT89 Crystal structure of d-mannonate dehydratase from chromohalobacter salexigens complexed with mg and glycerol
    21% identity, 73% coverage of query (50.8 bits)

4il2B / Q8FHC7 Crystal structure of d-mannonate dehydratase (rspa) from e. Coli cft073 (efi target efi-501585)
    23% identity, 88% coverage of query (50.8 bits)

3qkeA Crystal structure of d-mannonate dehydratase from chromohalobacter salexigens complexed with mg and d-gluconate
    21% identity, 73% coverage of query (50.8 bits)

MAND_ECOL6 / Q8FHC7 D-galactonate dehydratase family member RspA; D-mannonate dehydratase; Starvation sensing protein RspA homolog; EC 4.2.1.-; EC 4.2.1.8 from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
    23% identity, 88% coverage of query (50.8 bits)

3p93C Crystal structure of d-mannonate dehydratase from chromohalobacter salexigens complexed with mg,d-mannonate and 2-keto-3-deoxy-d- gluconate
    21% identity, 73% coverage of query (50.4 bits)

3p93A Crystal structure of d-mannonate dehydratase from chromohalobacter salexigens complexed with mg,d-mannonate and 2-keto-3-deoxy-d- gluconate
    21% identity, 73% coverage of query (50.4 bits)

3rgtA Crystal structure of d-mannonate dehydratase from chromohalobacter salexigens complexed with d-arabinohydroxamate
    20% identity, 73% coverage of query (50.4 bits)

MAND_SALG2 / B5RAG0 D-galactonate dehydratase family member RspA; D-mannonate dehydratase; Starvation sensing protein RspA homolog; EC 4.2.1.-; EC 4.2.1.8 from Salmonella gallinarum (strain 287/91 / NCTC 13346) (see paper)
    23% identity, 88% coverage of query (49.7 bits)

DMGD_CHRSD / Q1QT89 D-galactonate dehydratase family member ManD; D-gluconate dehydratase; D-mannonate dehydratase; EC 4.2.1.-; EC 4.2.1.39; EC 4.2.1.8 from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
    20% identity, 73% coverage of query (49.3 bits)

MAND1_CAUSK / B0T0B1 D-mannonate dehydratase Caul1427; ManD; EC 4.2.1.8 from Caulobacter sp. (strain K31) (see paper)
    22% identity, 71% coverage of query (47.8 bits)

4fi4A / B0T0B1 Crystal structure of mannonate dehydratase prk15072 (target efi- 502214) from caulobacter sp. K31
    22% identity, 71% coverage of query (47.8 bits)

MAND_PECCP / C6D9S0 D-galactonate dehydratase family member PC1_0802; D-mannonate dehydratase; EC 4.2.1.-; EC 4.2.1.8 from Pectobacterium carotovorum subsp. carotovorum (strain PC1) (see paper)
    22% identity, 88% coverage of query (47.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory