Searching for up to 100 curated homologs for N515DRAFT_1617 FitnessBrowser__Dyella79:N515DRAFT_1617 (590 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q93EN4 pyruvate decarboxylase (EC 4.1.1.1) from Sarcina ventriculi (see paper)
30% identity, 96% coverage of query (218 bits)
Q2UKV4 phenylpyruvate decarboxylase (EC 4.1.1.43) from Aspergillus oryzae (see paper)
30% identity, 95% coverage of query (211 bits)
pdc / Q5NYJ8 phenylpyruvate decarboxylase (EC 4.1.1.43) from Aromatoleum aromaticum (strain EbN1) (see 2 papers)
30% identity, 95% coverage of query (202 bits)
Build an alignment for N515DRAFT_1617 and 3 homologs with ≥ 30% identity
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PDC6 / P26263 pyruvate decarboxylase 3 monomer (EC 4.1.1.1; EC 4.1.1.80; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 9 papers)
PDC6_YEAST / P26263 Pyruvate decarboxylase isozyme 3; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
P26263 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 2 papers)
28% identity, 96% coverage of query (201 bits)
C4R3T2 pyruvate decarboxylase (EC 4.1.1.1) from Komagataella pastoris (see paper)
28% identity, 95% coverage of query (201 bits)
A0A068LJJ5 pyruvate decarboxylase (subunit 3/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
29% identity, 99% coverage of query (199 bits)
PDC4_SCHPO / O42873 Putative pyruvate decarboxylase C3G9.11c; EC 4.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
28% identity, 95% coverage of query (199 bits)
Q12629 pyruvate decarboxylase (EC 4.1.1.1) from Kluyveromyces lactis (see paper)
28% identity, 95% coverage of query (199 bits)
2vjyA / Q12629 Pyruvate decarboxylase from kluyveromyces lactis in complex with the substrate analogue methyl acetylphosphonate (see paper)
28% identity, 95% coverage of query (199 bits)
6efhA Pyruvate decarboxylase from kluyveromyces lactis soaked with pyruvamide
28% identity, 96% coverage of query (199 bits)
ipdC / P23234 indole-3-pyruvate decarboxylase subunit (EC 4.1.1.74) from Enterobacter cloacae (see 2 papers)
DCIP_ENTCL / P23234 Indole-3-pyruvate decarboxylase; Indolepyruvate decarboxylase; EC 4.1.1.74 from Enterobacter cloacae (see paper)
P23234 indolepyruvate decarboxylase (EC 4.1.1.74) from Enterobacter cloacae (see paper)
28% identity, 94% coverage of query (198 bits)
A0A068LJY3 pyruvate decarboxylase (subunit 2/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
28% identity, 97% coverage of query (197 bits)
PDC4_ARATH / Q9M040 Pyruvate decarboxylase 4; AtPDC4; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9M040 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
28% identity, 99% coverage of query (196 bits)
A0A068LJB0 pyruvate decarboxylase (subunit 1/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
28% identity, 98% coverage of query (196 bits)
2vbfB / Q6QBS4 The holostructure of the branched-chain keto acid decarboxylase (kdca) from lactococcus lactis (see paper)
27% identity, 96% coverage of query (194 bits)
2vbgA The complex structure of the branched-chain keto acid decarboxylase (kdca) from lactococcus lactis with 2r-1-hydroxyethyl-deazathdp
27% identity, 96% coverage of query (194 bits)
PDC1_CANGA / Q6FJA3 Pyruvate decarboxylase; EC 4.1.1.1 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus) (see paper)
27% identity, 95% coverage of query (192 bits)
6vgsBBB / A0A0B8QZ66 6vgsBBB (see paper)
25% identity, 96% coverage of query (192 bits)
PDC1 / P06169 pyruvate decarboxylase (EC 4.1.1.1; EC 4.1.1.80; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 8 papers)
PDC1_YEAST / P06169 Pyruvate decarboxylase isozyme 1; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 20 papers)
P06169 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 4 papers)
27% identity, 95% coverage of query (191 bits)
B0ZS79 pyruvate decarboxylase (EC 4.1.1.1) from Prunus armeniaca (see paper)
28% identity, 97% coverage of query (191 bits)
kivD / Q684J7 α-ketoisovalerate decarboxylase subunit (EC 4.1.1.72) from Lactococcus lactis subsp. lactis (see 2 papers)
Q684J7 pyruvate decarboxylase (EC 4.1.1.1); branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) from Lactococcus lactis subsp. lactis (see 6 papers)
25% identity, 96% coverage of query (191 bits)
1qpbA Pyruvate decarboyxlase from yeast (form b) complexed with pyruvamide
27% identity, 95% coverage of query (191 bits)
PDC1_ARATH / O82647 Pyruvate decarboxylase 1; AtPDC1; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
O82647 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
27% identity, 99% coverage of query (190 bits)
1ovmA / P23234 Crystal structure of indolepyruvate decarboxylase from enterobacter cloacae (see paper)
27% identity, 94% coverage of query (190 bits)
6efgD / Q12629 Pyruvate decarboxylase from kluyveromyces lactis
28% identity, 95% coverage of query (189 bits)
2w93A Crystal structure of the saccharomyces cerevisiae pyruvate decarboxylase variant e477q in complex with the surrogate pyruvamide
28% identity, 95% coverage of query (189 bits)
PDC13 / AAP75899.1 pyruvate decarboxylase from Lachancea kluyveri (see paper)
27% identity, 96% coverage of query (187 bits)
PDC3_ARATH / Q9M039 Pyruvate decarboxylase 3; AtPDC3; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9M039 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
28% identity, 98% coverage of query (187 bits)
Q92345 Probable pyruvate decarboxylase C1F8.07c; EC 4.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
27% identity, 96% coverage of query (187 bits)
A0A068LQF7 pyruvate decarboxylase (EC 4.1.1.1) from Hevea brasiliensis (see paper)
28% identity, 98% coverage of query (186 bits)
PDC2_ARATH / Q9FFT4 Pyruvate decarboxylase 2; AtPDC2; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9FFT4 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see 2 papers)
27% identity, 97% coverage of query (185 bits)
2vk1A / P06169 Crystal structure of the saccharomyces cerevisiae pyruvate decarboxylase variant d28a in complex with its substrate (see paper)
27% identity, 95% coverage of query (184 bits)
THI3 / Q07471 keto-isocaproate decarboxylase subunit (EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
THI3_YEAST / Q07471 Thiamine metabolism regulatory protein THI3; Keto isocaproate decarboxylase 1; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.72 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
Q07471 branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) from Saccharomyces cerevisiae (see 2 papers)
25% identity, 94% coverage of query (184 bits)
Q9UUT6 pyruvate decarboxylase (EC 4.1.1.1) from Zygosaccharomyces bisporus (see paper)
28% identity, 95% coverage of query (183 bits)
PDC5 / P16467 pyruvate decarboxylase 2 monomer (EC 4.1.1.1; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 8 papers)
PDC5_YEAST / P16467 Pyruvate decarboxylase isozyme 2; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 15 papers)
P16467 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 2 papers)
27% identity, 96% coverage of query (182 bits)
8hp4A / C5MDS4 Ctpdc complex
28% identity, 95% coverage of query (182 bits)
ipdC / P71323 indolepyruvate decarboxylase subunit (EC 4.1.1.74) from Enterobacter agglomerans (see paper)
29% identity, 95% coverage of query (181 bits)
5npuA Inferred ancestral pyruvate decarboxylase (see paper)
26% identity, 96% coverage of query (181 bits)
PDC1_CANAL / P83779 Pyruvate decarboxylase; EC 4.1.1.1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see paper)
PDC11 pyruvate decarboxylase from Candida albicans (see 5 papers)
27% identity, 95% coverage of query (180 bits)
V6RPS5 pyruvate decarboxylase (EC 4.1.1.1) from Fusarium graminearum (see paper)
27% identity, 94% coverage of query (172 bits)
PDC12 / AAP75898.1 pyruvate decarboxylase from Lachancea kluyveri (see paper)
28% identity, 96% coverage of query (172 bits)
PDC1 / P51850 pyruvate decarboxylase (EC 4.1.1.1) from Pisum sativum (see paper)
27% identity, 98% coverage of query (170 bits)
2vbiA / Q8L388 Holostructure of pyruvate decarboxylase from acetobacter pasteurianus
26% identity, 96% coverage of query (168 bits)
2q5oA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp and phenylpyruvate
27% identity, 95% coverage of query (168 bits)
C7JF72 pyruvate decarboxylase (EC 4.1.1.1) from Acetobacter pasteurianus (see paper)
26% identity, 96% coverage of query (167 bits)
2q5qA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp and 5-phenyl-2-oxo-valeric acid
27% identity, 95% coverage of query (167 bits)
Q8L388 pyruvate decarboxylase (EC 4.1.1.1) from Acetobacter pasteurianus (see paper)
26% identity, 96% coverage of query (164 bits)
ipdC / P51852 phenylpyruvate decarboxylase (EC 4.1.1.43) from Azospirillum brasilense (see 2 papers)
P51852 indolepyruvate decarboxylase (EC 4.1.1.74) from Azospirillum brasilense (see 2 papers)
27% identity, 95% coverage of query (162 bits)
A9H275 pyruvate decarboxylase (EC 4.1.1.1) from Gluconacetobacter diazotrophicus (see paper)
27% identity, 96% coverage of query (161 bits)
4cokB / A9H275 Functional and structural characterization of pyruvate decarboxylase from gluconoacetobacter diazotrophicus (see paper)
27% identity, 96% coverage of query (160 bits)
A0A075Q354 pyruvate decarboxylase (EC 4.1.1.1) from Gluconacetobacter diazotrophicus (see paper)
27% identity, 96% coverage of query (160 bits)
A0A125STX6 pyruvate decarboxylase (EC 4.1.1.1) from Phanerochaete sordida (see paper)
27% identity, 82% coverage of query (159 bits)
2nxwA Crystal structure of phenylpyruvate decarboxylase of azospirillum brasilense
27% identity, 95% coverage of query (157 bits)
2q5lA / P51852 X-ray structure of phenylpyruvate decarboxylase in complex with 2-(1- hydroxyethyl)-3-deaza-thdp (see paper)
26% identity, 95% coverage of query (156 bits)
2q5jA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp
26% identity, 95% coverage of query (154 bits)
ipdC / CAA67899.1 indole-3-pyruvate decarboxylase from Azospirillum brasilense (see paper)
27% identity, 95% coverage of query (152 bits)
5eujE / Q8KTX6 5eujE (see paper)
25% identity, 94% coverage of query (146 bits)
1zpdA Pyruvate decarboxylase from zymomonas mobilis
25% identity, 96% coverage of query (146 bits)
Q659I2 pyruvate decarboxylase (EC 4.1.1.1) from Wickerhamomyces anomalus (see paper)
27% identity, 83% coverage of query (145 bits)
pdc / P06672 pyruvate decarboxylase monomer (EC 4.1.1.1) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
P06672 pyruvate decarboxylase (EC 4.1.1.1) from Zymomonas mobilis (see 5 papers)
25% identity, 96% coverage of query (144 bits)
2wvgA Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
25% identity, 96% coverage of query (144 bits)
2wvaE Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
25% identity, 96% coverage of query (144 bits)
2wvaA Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
25% identity, 96% coverage of query (144 bits)
P06672 Pyruvate decarboxylase; PDC; EC 4.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
25% identity, 96% coverage of query (144 bits)
Q8KTX6 pyruvate decarboxylase (EC 4.1.1.1) from Zymobacter palmae (see paper)
25% identity, 94% coverage of query (143 bits)
3oe1A Pyruvate decarboxylase variant glu473asp from z. Mobilis in complex with reaction intermediate 2-lactyl-thdp
25% identity, 96% coverage of query (142 bits)
5tmaA / P06672 Zymomonas mobilis pyruvate decarboxylase mutant pdc-2.3 (see paper)
25% identity, 96% coverage of query (141 bits)
D9J047 pyruvate dehydrogenase system (EC 1.2.1.104); pyruvate decarboxylase (EC 4.1.1.1) from Zymomonas mobilis (see paper)
25% identity, 96% coverage of query (140 bits)
ARO10 / Q06408 2-keto-3-methylvalerate decarboxylase subunit (EC 4.1.1.1; EC 4.1.1.74; EC 4.1.1.43; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 5 papers)
ARO10_YEAST / Q06408 Transaminated amino acid decarboxylase; Thiamine diphosphate-dependent phenylpyruvate decarboxylase; PPDC; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; Transaminated branched-chain amino acid decarboxylase; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74; EC 4.1.1.80 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
Q06408 phenylpyruvate decarboxylase (EC 4.1.1.43) from Saccharomyces cerevisiae (see paper)
24% identity, 96% coverage of query (123 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
23% identity, 96% coverage of query (93.2 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
24% identity, 94% coverage of query (84.0 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
24% identity, 93% coverage of query (82.8 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
23% identity, 92% coverage of query (82.8 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
23% identity, 92% coverage of query (80.9 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
23% identity, 92% coverage of query (80.9 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
23% identity, 92% coverage of query (80.5 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
23% identity, 92% coverage of query (80.5 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
23% identity, 92% coverage of query (80.5 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
22% identity, 93% coverage of query (79.3 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
21% identity, 96% coverage of query (78.2 bits)
1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
23% identity, 92% coverage of query (78.2 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
23% identity, 92% coverage of query (78.2 bits)
AT5G17380 / Q9LF46 oxalyl-CoA decarboxylase (EC 4.1.1.8) from Arabidopsis thaliana (see 5 papers)
25% identity, 92% coverage of query (77.4 bits)
ilvB / AAA93098.1 acetolactate synthase from Streptomyces avermitilis (see paper)
21% identity, 93% coverage of query (77.4 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
24% identity, 94% coverage of query (77.4 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
22% identity, 92% coverage of query (77.0 bits)
G0ZSE6 acetolactate synthase (EC 2.2.1.6) from Pseudomonas sp. (see paper)
23% identity, 94% coverage of query (76.6 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
22% identity, 92% coverage of query (76.6 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
22% identity, 92% coverage of query (76.3 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
23% identity, 94% coverage of query (76.3 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
23% identity, 92% coverage of query (75.5 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
23% identity, 92% coverage of query (75.5 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
22% identity, 92% coverage of query (74.3 bits)
5d6rB Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor
23% identity, 95% coverage of query (70.9 bits)
5dx6B / P27696 Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
23% identity, 95% coverage of query (70.5 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
21% identity, 93% coverage of query (68.6 bits)
5dx6A Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
22% identity, 95% coverage of query (67.8 bits)
1ozgA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
23% identity, 95% coverage of query (67.4 bits)
5wdgA Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate
23% identity, 95% coverage of query (67.4 bits)
1ozfA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
22% identity, 95% coverage of query (67.0 bits)
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