Sites on a Tree

 

Searching for up to 100 curated homologs for N515DRAFT_1736 FitnessBrowser__Dyella79:N515DRAFT_1736 (451 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

OXCT1 / P55809 succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) from Homo sapiens (see 4 papers)
SCOT1_HUMAN / P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Homo sapiens (Human) (see 7 papers)
P55809 3-oxoacid CoA-transferase (EC 2.8.3.5) from Homo sapiens (see 3 papers)
    56% identity, 99% coverage of query (528 bits)

1o9lA / Q29551 Succinate:coenzyme-a transferase (pig heart)
    55% identity, 99% coverage of query (522 bits)

3k6mC Dynamic domains of succinyl-coa:3-ketoacid-coenzyme a transferase from pig heart.
    55% identity, 99% coverage of query (522 bits)

SCOT1_PIG / Q29551 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinate-coenzyme A transferase; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Sus scrofa (Pig) (see 6 papers)
Q29551 3-oxoacid CoA-transferase (EC 2.8.3.5) from Sus scrofa (see 3 papers)
    55% identity, 99% coverage of query (520 bits)

2nrbA / Q29551 C28s mutant of succinyl-coa:3-ketoacid coa transferase from pig heart (see paper)
    55% identity, 99% coverage of query (519 bits)

SCOT1_RAT / B2GV06 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Rattus norvegicus (Rat) (see paper)
B2GV06 3-oxoacid CoA-transferase (EC 2.8.3.5) from Rattus norvegicus (see 2 papers)
    57% identity, 95% coverage of query (518 bits)

3oxoE Succinyl-coa:3-ketoacid coa transferase from pig heart covalently bound to coa
    55% identity, 99% coverage of query (518 bits)

Q9D0K2 3-oxoacid CoA-transferase (EC 2.8.3.5) from Mus musculus (see paper)
    57% identity, 95% coverage of query (516 bits)

SCOT_DROME / Q9W058 Succinyl-CoA:3-ketoacid-coenzyme A transferase, mitochondrial; 3-oxoacid CoA-transferase; EC 2.8.3.5 from Drosophila melanogaster (Fruit fly) (see paper)
Q9W058 3-oxoacid CoA-transferase (EC 2.8.3.5) from Drosophila melanogaster (see paper)
    54% identity, 99% coverage of query (505 bits)

SCOT2_HUMAN / Q9BYC2 Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial; 3-oxoacid CoA-transferase 2A; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase; SCOT-t; EC 2.8.3.5 from Homo sapiens (Human) (see paper)
Q9BYC2 3-oxoacid CoA-transferase (EC 2.8.3.5) from Homo sapiens (see paper)
    55% identity, 99% coverage of query (492 bits)

SCO2A_RAT / Q5XIJ9 Succinyl-CoA:3-ketoacid coenzyme A transferase 2A, mitochondrial; 3-oxoacid CoA-transferase 2A; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 1; SCOT-t1; EC 2.8.3.5 from Rattus norvegicus (Rat) (see paper)
    53% identity, 99% coverage of query (488 bits)

Q9JJN4 3-oxoacid CoA-transferase (EC 2.8.3.5) from Mus musculus (see paper)
    54% identity, 99% coverage of query (484 bits)

SCO2B_MOUSE / Q9ESL0 Succinyl-CoA:3-ketoacid coenzyme A transferase 2B, mitochondrial; 3-oxoacid CoA-transferase 2B; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase 2; SCOT-t2; EC 2.8.3.5 from Mus musculus (Mouse) (see paper)
    54% identity, 99% coverage of query (481 bits)

8i3yD / Q386P1 Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
    53% identity, 98% coverage of query (466 bits)

8i40A Crystal structure of asct from trypanosoma brucei in complex with coa.
    52% identity, 98% coverage of query (461 bits)

8i3yA Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
    52% identity, 98% coverage of query (456 bits)

Build an alignment

Build an alignment for N515DRAFT_1736 and 16 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

CARA_ACEWO / F1CYZ5 Caffeate CoA-transferase; Hydrocaffeyl-CoA:caffeate CoA transferase; EC 2.8.3.23 from Acetobacterium woodii (see 2 papers)
F1CYZ5 caffeate CoA-transferase (EC 2.8.3.23) from Acetobacterium woodii (see 2 papers)
    27% identity, 96% coverage of query (111 bits)

2ahvA / Q8X5X6 Crystal structure of acyl-coa transferase from e. Coli o157:h7 (ydif)- thioester complex with coa- 1 (see paper)
    26% identity, 84% coverage of query (85.1 bits)

YdiF / b1694 putative acetate-CoA transferase YdiF (EC 2.8.3.9) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    25% identity, 84% coverage of query (84.3 bits)

YDIF_ECO57 / Q8X5X6 Acetate CoA-transferase YdiF; Short-chain acyl-CoA:acetate CoA-transferase; EC 2.8.3.8 from Escherichia coli O157:H7 (see paper)
    25% identity, 84% coverage of query (84.3 bits)

Q9L3F7 propionate CoA-transferase (EC 2.8.3.1) from Anaerotignum propionicum (see paper)
    25% identity, 96% coverage of query (77.8 bits)

BWI76_RS23700 glycerate CoA-transferase from Klebsiella michiganensis M5al
    24% identity, 85% coverage of query (71.2 bits)

pct / G0VND6 propanoyl-CoA transferase monomer (EC 2.8.3.1) from Megasphaera elsdenii DSM 20460 (see 3 papers)
A0A140JTF0 propionate CoA-transferase (EC 2.8.3.1) from Megasphaera elsdenii (see paper)
    26% identity, 96% coverage of query (70.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory