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Searching for up to 100 curated homologs for N515DRAFT_2628 FitnessBrowser__Dyella79:N515DRAFT_2628 (275 a.a.)

Found high-coverage hits (≥70%) to 91 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

cpoL / PDB|1A88_A non-heme chloroperoxidase; EC 1.11.1.10 from Streptomyces lividans (see 2 papers)
cpoL / AAA18642.1 chloroperoxidase from Streptomyces lividans (see paper)
    69% identity, 98% coverage of query (401 bits)

cpo / GI|151186 chloroperoxidase; EC 1.11.1.10 from Burkholderia pyrrocinia (see 2 papers)
cpo / AAA02837.1 chloroperoxidase from Burkholderia pyrrocinia (see paper)
    69% identity, 98% coverage of query (398 bits)

P25026 Non-heme chloroperoxidase; Chloride peroxidase; Chloroperoxidase P; CPO-P; EC 1.11.1.- from Burkholderia pyrrocinia (Pseudomonas pyrrocinia)
    69% identity, 98% coverage of query (398 bits)

Q3HWU8 carboxylesterase (EC 3.1.1.1) from Pseudomonas putida (see paper)
    67% identity, 98% coverage of query (394 bits)

DCH_ACICA / Q83WC8 Bifunctional esterase/perhydrolase DCH; 3,4-dihydrocoumarin hydrolase; DCH; Metal-free haloperoxidase; EC 3.1.1.35 from Acinetobacter calcoaceticus (see 3 papers)
Q83WC8 dihydrocoumarin hydrolase (EC 3.1.1.35) from Acinetobacter calcoaceticus (see paper)
    68% identity, 98% coverage of query (385 bits)

thcF / AAC45285.1 chloroperoxidase from Rhodococcus erythropolis (see 2 papers)
    63% identity, 98% coverage of query (380 bits)

cpoF / PDB|1A8S non-heme chloroperoxidase; EC 1.11.1.10 from Pseudomonas fluorescens (see 2 papers)
    63% identity, 99% coverage of query (365 bits)

3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase
    49% identity, 99% coverage of query (280 bits)

3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase
    49% identity, 99% coverage of query (279 bits)

ESTE_PSEFL / P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 8 papers)
GI|951089 arylesterase; EC 1.-.-.-; EC 3.1.1.2 from Pseudomonas fluorescens (see 3 papers)
AAB60168.1 esterase from Pseudomonas fluorescens (see 2 papers)
    48% identity, 99% coverage of query (276 bits)

3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog
    48% identity, 99% coverage of query (275 bits)

8pi1B / P22862 Bicyclic incypro pseudomonas fluorescens esterase (see paper)
    49% identity, 98% coverage of query (273 bits)

CPOA1_KITAU / P33912 Non-heme chloroperoxidase CPO-A1; CPO-A1; BPO1; Bromide peroxidase; Non-haem bromoperoxidase BPO-A1; EC 1.11.1.- from Kitasatospora aureofaciens (Streptomyces aureofaciens) (see paper)
PDB|1A8Q non-heme bromoperoxidase; EC 1.11.1.- from Streptomyces aureofaciens (see 3 papers)
bpoA1 / AAC43253.1 bromoperoxidase BPO-A1 from Kitasatospora aureofaciens (see 2 papers)
    49% identity, 98% coverage of query (248 bits)

P29715 bromide peroxidase (EC 1.11.1.18) from Kitasatospora aureofaciens (see 2 papers)
bpoA2 / GI|150457 non-heme bromoperoxidase BPO-A2; EC 1.11.1.- from Streptomyces aureofaciens (see 4 papers)
    40% identity, 96% coverage of query (189 bits)

cpoT / GB|AAB86626.1 non-heme chloroperoxidase from Streptomyces aureofaciens (see paper)
    40% identity, 96% coverage of query (189 bits)

E3SVS0 amidase (EC 3.5.1.4) from Microbacterium hydrocarbonoxydans (see paper)
    37% identity, 96% coverage of query (182 bits)

1hl7A / Q8GJP7 Gamma lactamase from an aureobacterium species in complex with 3a,4,7, 7a-tetrahydro-benzo [1,3] dioxol-2-one (see paper)
    37% identity, 96% coverage of query (182 bits)

Build an alignment

Build an alignment for N515DRAFT_2628 and 17 homologs with ≥ 30% identity

Select sequences

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Change minimum %identity:

Additional hits (identity < 30%)

5h3hB / K0ACL0 Esterase (eaest) from exiguobacterium antarcticum (see paper)
    27% identity, 100% coverage of query (115 bits)

6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
    25% identity, 92% coverage of query (71.2 bits)

6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
    25% identity, 92% coverage of query (69.7 bits)

6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
    25% identity, 92% coverage of query (69.3 bits)

bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
    24% identity, 86% coverage of query (65.1 bits)

2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
    27% identity, 98% coverage of query (63.2 bits)

Q6DND9 haloalkane dehalogenase (EC 3.8.1.5) from Lyngbya majuscula (see paper)
    24% identity, 99% coverage of query (62.8 bits)

cmpF / CAB06612.1 2-hydroxymuconic semialdehyde hydrolase from Sphingomonas sp (see 2 papers)
    26% identity, 96% coverage of query (61.6 bits)

P96965 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas fluorescens (see 2 papers)
cumD / BAA12150.1 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase from Pseudomonas fluorescens (see paper)
    26% identity, 98% coverage of query (61.2 bits)

1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
    26% identity, 98% coverage of query (60.5 bits)

AO353_17230 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas fluorescens FW300-N2E3
    31% identity, 71% coverage of query (60.5 bits)

1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
    25% identity, 98% coverage of query (60.1 bits)

1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
    25% identity, 98% coverage of query (60.1 bits)

1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
    25% identity, 98% coverage of query (60.1 bits)

1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
    25% identity, 98% coverage of query (60.1 bits)

1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
    25% identity, 98% coverage of query (60.1 bits)

pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
    25% identity, 71% coverage of query (58.9 bits)

Q0SH24 3-oxoadipate enol-lactonase (EC 3.1.1.24); 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) from Rhodococcus jostii (see paper)
    25% identity, 71% coverage of query (58.9 bits)

carC / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase monomer (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
CARC_PSERE / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid hydrolase; HOPDA; EC 3.7.1.13 from Pseudomonas resinovorans (see 3 papers)
Q9AQM4 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
carC / BAC41548.1 meta cleavage compound hydrolase from Pseudomonas resinovorans (see 9 papers)
    24% identity, 99% coverage of query (57.4 bits)

pcaD / Q88N36 subunit of 3-oxoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
Q88N36 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Pseudomonas putida (see paper)
    26% identity, 80% coverage of query (57.4 bits)

todF / P23133 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase (EC 3.7.1.25) from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) (see paper)
TODF_PSEP1 / P23133 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase; HOHH; EC 3.7.1.25 from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) (see 2 papers)
    26% identity, 90% coverage of query (57.0 bits)

aamsh1 / Q988D4 2-(acetamidomethylene)succinate hydrolase monomer (EC 3.5.1.29) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 7 papers)
AAMHY_RHILO / Q988D4 2-(acetamidomethylene)succinate hydrolase; alpha-(N-acetylaminomethylene)succinic acid amidohydrolase; AAMS amidohydrolase; EC 3.5.1.29 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see 2 papers)
Q988D4 2-(acetamidomethylene)succinate hydrolase (EC 3.5.1.29) from Mesorhizobium loti (see 2 papers)
    23% identity, 96% coverage of query (57.0 bits)

Q8KT44 carboxylesterase (EC 3.1.1.1) from Lacticaseibacillus casei (see paper)
    23% identity, 91% coverage of query (55.8 bits)

Q84II3 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Janthinobacterium sp. J3 (see paper)
    23% identity, 99% coverage of query (55.8 bits)

dehH1 / Q01398 fluoroacetate dehalogenase monomer (EC 3.8.1.3) from Moraxella sp. (strain B) (see 2 papers)
dehH1 / RF|NP_904256.1 haloacetate dehalogenase H-1; EC 3.8.1.3 from Moraxella sp. B (see paper)
dehH1 / BAB85585.1 haloacetate dehalogenase H-1 from Delftia acidovorans (see 3 papers)
dehH1 / BAC81979.1 haloacetate dehalogenase H-1 from Delftia acidovorans (see 3 papers)
    24% identity, 91% coverage of query (55.1 bits)

ols / B1XKC6 fatty-acyl-[acp] elongase/decarboxylase from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
    24% identity, 92% coverage of query (53.9 bits)

BPOC_MYCTU / P9WNH1 Putative non-heme bromoperoxidase BpoC from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    28% identity, 80% coverage of query (53.9 bits)

MGLL_MYCS2 / A0QNZ7 Monoacylglycerol lipase; MGL; EC 3.1.1.23 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    27% identity, 89% coverage of query (53.9 bits)

O73957 carboxylesterase (EC 3.1.1.1) from Sulfolobus acidocaldarius (see paper)
    24% identity, 96% coverage of query (53.5 bits)

hbpD / O06648 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoate hydrolase [multifunctional] (EC 3.7.1.8) from Pseudomonas nitroreducens (see 2 papers)
    23% identity, 96% coverage of query (52.4 bits)

TGND_ACIAD / Q6F9F4 (E)-2-((N-methylformamido)methylene)succinate hydrolase; MFMS hydrolase; EC 3.5.1.- from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    26% identity, 77% coverage of query (51.2 bits)

tesD / Q83VZ6 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase (EC 3.7.1.17) from Comamonas testosteroni (see 3 papers)
    23% identity, 95% coverage of query (50.4 bits)

7ondA Halotag engineering for enhanced fluorogenicity and kinetics with a styrylpyridine dye
    24% identity, 96% coverage of query (48.1 bits)

P59336 Haloalkane dehalogenase; EC 3.8.1.5 from Rhodococcus sp. (strain TDTM0003)
    24% identity, 97% coverage of query (47.4 bits)

1cqwA Nai cocrystallised with haloalkane dehalogenase from a rhodococcus species
    24% identity, 97% coverage of query (47.4 bits)

4kyvB Crystal structure of dehalogenase halotag2 with halts at the resolution 1.8a. Northeast structural genomics consortium (nesg) target or150
    24% identity, 97% coverage of query (46.2 bits)

4kacA X-ray structure of the complex halotag2 with halts. Northeast structural genomics consortium (nesg) target or150.
    24% identity, 97% coverage of query (46.2 bits)

4o08A Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor
    22% identity, 82% coverage of query (45.8 bits)

7o8bA Structure of haloalkane dehalogenase variant dhaa80 from rhodococcus rhodochrous
    24% identity, 97% coverage of query (45.8 bits)

7o3oA Structure of haloalkane dehalogenase mutant dhaa80(t148l, g171q, a172v, c176f) from rhodococcus rhodochrous with ionic liquid
    24% identity, 97% coverage of query (45.8 bits)

BPHD_PARXL / P47229 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase; EC 3.7.1.8 from Paraburkholderia xenovorans (strain LB400) (see 2 papers)
P47229 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Paraburkholderia xenovorans (see 2 papers)
BphD / CAA46911.1 2-hydroxy-6-oxo-6-phenylhexa-2, 4-dienoate hydrolase from Pseudomonas sp (see paper)
    23% identity, 95% coverage of query (45.8 bits)

7zizA X-ray structure of the dead variant haloalkane dehalogenase halotag7- d106a bound to a pentanol tetramethylrhodamine ligand (tmr-hy5)
    24% identity, 96% coverage of query (45.8 bits)

2og1A / P47229 Crystal structure of bphd, a c-c hydrolase from burkholderia xenovorans lb400 (see paper)
    23% identity, 95% coverage of query (45.8 bits)

4io0A / G9BEX6 Crystal structure of f128a mutant of an epoxide hydrolase from bacillus megaterium complexed with its product (r)-3-[1]naphthyloxy- propane-1,2-diol (see paper)
    22% identity, 82% coverage of query (45.4 bits)

7wamA Crystal structure of halotag complexed with vl1
    23% identity, 96% coverage of query (45.4 bits)

7c8lA Hybrid designing of potent inhibitors of striga strigolactone receptor shhtl7
    21% identity, 87% coverage of query (45.4 bits)

7snuA / A0A0M3PNA2 Crystal structure of shhtl7 from striga hermonthica in complex with strigolactone antagonist rg6 (see paper)
    21% identity, 87% coverage of query (45.4 bits)

7wanA Crystal structure of halotag complexed with ul2
    23% identity, 96% coverage of query (45.1 bits)

8b6rA X-ray structure of the haloalkane dehalogenase halotag7 labeled with a chloroalkane cyanine3 fluorophore substrate
    24% identity, 96% coverage of query (45.1 bits)

7zj0A X-ray structure of the haloalkane dehalogenase halotag7 bound to a pentylmethanesulfonamide tetramethylrhodamine ligand (tmr-s5)
    24% identity, 96% coverage of query (45.1 bits)

7ziyB X-ray structure of the haloalkane dehalogenase halotag7 bound to a pentyltrifluoromethanesulfonamide tetramethylrhodamine ligand (tmr- t5)
    24% identity, 96% coverage of query (45.1 bits)

7ziyA X-ray structure of the haloalkane dehalogenase halotag7 bound to a pentyltrifluoromethanesulfonamide tetramethylrhodamine ligand (tmr- t5)
    24% identity, 96% coverage of query (45.1 bits)

7zixA X-ray structure of the haloalkane dehalogenase halotag7 bound to a butylmethanesulfonamide tetramethylrhodamine ligand (tmr-s4)
    24% identity, 96% coverage of query (45.1 bits)

7ziwA X-ray structure of the haloalkane dehalogenase halotag7 bound to a butyltrifluoromethanesulfonamide tetramethylrhodamine ligand (tmr-t4)
    24% identity, 96% coverage of query (45.1 bits)

6y7bA X-ray structure of the haloalkane dehalogenase halotag7 labeled with a chloroalkane-carbopyronine fluorophore substrate
    24% identity, 96% coverage of query (45.1 bits)

5z7yA Crystal structure of striga hermonthica htl7 (shhtl7)
    21% identity, 87% coverage of query (45.1 bits)

7zbdB Halotag with traq-g ligand
    24% identity, 96% coverage of query (45.1 bits)

7zbaA Halotag with me-traq-g ligand
    24% identity, 96% coverage of query (45.1 bits)

5vnpA X-ray crystal structure of halotag bound to the p1 benzoxadiazole fluorogenic ligand
    24% identity, 96% coverage of query (45.1 bits)

5uxzA X-ray crystal structure of halotag bound to the p9 benzothiadiazole fluorogenic ligand
    24% identity, 96% coverage of query (45.1 bits)

5y2yA Crystal structure of halotag (m175c) complexed with dansyl-peg2- halotag ligand
    23% identity, 96% coverage of query (45.1 bits)

4lyeA Crystal structure of the s105a mutant of a c-c hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with substrate hopda
    24% identity, 84% coverage of query (45.1 bits)

4lxiA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 5, 8-dif hopda
    24% identity, 84% coverage of query (45.1 bits)

4lxhA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 3- cl hopda (see paper)
    24% identity, 84% coverage of query (45.1 bits)

7zbdA Halotag with traq-g ligand
    24% identity, 96% coverage of query (45.1 bits)

6u32A Crystal structure of halotag bound to tetramethylrhodamine-halotag ligand
    24% identity, 96% coverage of query (45.1 bits)

7zbbA Halotag with traq-g-ctrl ligand
    24% identity, 96% coverage of query (45.1 bits)

P0A3G3 Haloalkane dehalogenase; EC 3.8.1.5 from Rhodococcus sp.
    24% identity, 97% coverage of query (44.7 bits)

4hzgA Structure of haloalkane dehalogenase dhaa from rhodococcus rhodochrous
    24% identity, 97% coverage of query (44.7 bits)

8agnAAA Alpha/beta epoxide hydrolase
    24% identity, 99% coverage of query (44.3 bits)

8agmAAA Alpha/beta epoxide hydrolase
    24% identity, 99% coverage of query (44.3 bits)

8agpAAA Alpha/beta epoxide hydrolase
    24% identity, 99% coverage of query (43.9 bits)

5ng7B Novel epoxide hydrolases belonging to the alpha/beta hydrolases superfamily in metagenomes from hot environments
    24% identity, 99% coverage of query (43.9 bits)

8agsAAA / A0A1U9WZ52 8agsAAA
    24% identity, 99% coverage of query (43.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory