Searching for up to 100 curated homologs for N515DRAFT_2874 FitnessBrowser__Dyella79:N515DRAFT_2874 (470 a.a.)
Found high-coverage hits (≥70%) to 62 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
5fn0A / Q84HF5 Crystal structure of pseudomonas fluorescens kynurenine-3- monooxygenase (kmo) in complex with gsk180 (see paper)
52% identity, 98% coverage of query (433 bits)
KMO_PSEFL / Q84HF5 Kynurenine 3-monooxygenase; PfKMO; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Pseudomonas fluorescens (see 5 papers)
Q84HF5 kynurenine 3-monooxygenase (EC 1.14.13.9) from Pseudomonas fluorescens (see 4 papers)
52% identity, 98% coverage of query (432 bits)
5nakA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with the enzyme substrate l-kynurenine
52% identity, 97% coverage of query (432 bits)
6foxA The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with kynurenine
52% identity, 97% coverage of query (431 bits)
6fp1A The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 1
53% identity, 97% coverage of query (426 bits)
5nahA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-{5-chloro-6-[(1r)-1-(6-methylpyridazin-3-yl)ethoxy]-1,2- benzoxazol-3-yl}propanoic acid
52% identity, 97% coverage of query (425 bits)
5nagA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-{5-chloro-6-[(1r)-1-(pyridin-2-yl)ethoxy]-1,2-benzoxazol-3- yl}propanoic acid
52% identity, 97% coverage of query (425 bits)
5naeA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-{5-chloro-2-oxo-6-[(1r)-1-(pyridin-2-yl)ethoxy]-2,3-dihydro-1, 3-benzoxazol-3-yl}propanoic acid
52% identity, 97% coverage of query (425 bits)
5nabA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-(5-chloro-6-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl) propanoic acid
52% identity, 97% coverage of query (425 bits)
5mzkA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-[5-chloro-6-(cyclobutylmethoxy)-2-oxo-2,3-dihydro-1,3- benzoxazol-3-yl]propanoic acid
52% identity, 97% coverage of query (425 bits)
5mziA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-(5-chloro-6-cyclopropoxy-2-oxo-2,3-dihydro-1,3-benzoxazol-3- yl)propanoic acid
52% identity, 97% coverage of query (425 bits)
5mzcA Pseudomonas fluorescens kynurenine 3-monooxygenase (kmo) in complex with 3-(5-chloro-6-ethoxy-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl) propanoic acid
52% identity, 97% coverage of query (425 bits)
6fp0B The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 4
52% identity, 97% coverage of query (422 bits)
6foyA The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 9
52% identity, 97% coverage of query (421 bits)
6fphA The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 1h
52% identity, 97% coverage of query (420 bits)
6fozA The crystal structure of p.Fluorescens kynurenine 3-monooxygenase (kmo) in complex with competitive inhibitor no. 13
51% identity, 97% coverage of query (417 bits)
5x6qA Crystal structure of pseudomonas fluorescens kmo in complex with ro 61-8048
51% identity, 97% coverage of query (415 bits)
KMO_CYTH3 / Q11PP7 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Cytophaga hutchinsonii (strain ATCC 33406 / DSM 1761 / CIP 103989 / NBRC 15051 / NCIMB 9469 / D465) (see paper)
Q11PP7 kynurenine 3-monooxygenase (EC 1.14.13.9) from Cytophaga hutchinsonii (see paper)
40% identity, 92% coverage of query (308 bits)
KMO / O15229 kynurenine 3-monooxygenase (EC 1.14.13.9) from Homo sapiens (see 3 papers)
KMO_HUMAN / O15229 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Homo sapiens (Human) (see 8 papers)
O15229 kynurenine 3-monooxygenase (EC 1.14.13.9) from Homo sapiens (see 6 papers)
37% identity, 92% coverage of query (290 bits)
KMO_MOUSE / Q91WN4 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Mus musculus (Mouse) (see 3 papers)
Q91WN4 kynurenine 3-monooxygenase (EC 1.14.13.9) from Mus musculus (see 2 papers)
38% identity, 93% coverage of query (285 bits)
Q9MZS9 kynurenine 3-monooxygenase (EC 1.14.13.9) from Sus scrofa (see 2 papers)
38% identity, 93% coverage of query (282 bits)
Q8ISJ5 kynurenine 3-monooxygenase (EC 1.14.13.9) from Anopheles stephensi (see paper)
38% identity, 93% coverage of query (280 bits)
KMO_RAT / O88867 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Rattus norvegicus (Rat) (see 3 papers)
O88867 kynurenine 3-monooxygenase (EC 1.14.13.9) from Rattus norvegicus (see 2 papers)
38% identity, 89% coverage of query (274 bits)
Q95NP6 kynurenine 3-monooxygenase (EC 1.14.13.9) from Tribolium castaneum (see paper)
37% identity, 88% coverage of query (264 bits)
KMO_AEDAE / Q86PM2 Kynurenine 3-monooxygenase; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti) (see paper)
Q86PM2 kynurenine 3-monooxygenase (EC 1.14.13.9) from Aedes aegypti (see paper)
37% identity, 90% coverage of query (263 bits)
6lkdA In meso full-length rat kmo in complex with a pyrazoyl benzoic acid inhibitor
37% identity, 89% coverage of query (263 bits)
6lkeA / O88867 In meso full-length rat kmo in complex with an inhibitor identified via DNA-encoded chemical library screening (see paper)
37% identity, 89% coverage of query (261 bits)
5x68B / O15229 Crystal structure of human kmo (see paper)
38% identity, 80% coverage of query (249 bits)
orf19.5443 kynurenine 3-monooxygenase; EC 1.14.13.9 from Candida albicans (see 2 papers)
33% identity, 92% coverage of query (249 bits)
KMO_YEAST / P38169 Kynurenine 3-monooxygenase; Biosynthesis of nicotinic acid protein 4; Kynurenine 3-hydroxylase; EC 1.14.13.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P38169 kynurenine 3-monooxygenase (EC 1.14.13.9) from Saccharomyces cerevisiae (see paper)
33% identity, 92% coverage of query (238 bits)
4j34B / P38169 Crystal structure of kynurenine 3-monooxygenase - truncated at position 394 plus his tag cleaved. (see paper)
35% identity, 82% coverage of query (221 bits)
sibC / C0LTL7 kynurenine 3-monooxygenase (EC 1.14.13.9) from Streptosporangium sibiricum (see paper)
35% identity, 96% coverage of query (220 bits)
5x6rA Crystal structure of saccharomyces cerevisiae kmo in complex with ro 61-8048
35% identity, 82% coverage of query (218 bits)
4j36B Cocrystal structure of kynurenine 3-monooxygenase in complex with upf 648 inhibitor(kmo-394upf)
36% identity, 76% coverage of query (207 bits)
ecm4 / Q0X0C0 (2S,3R)-4-(2-aminophenyl)-2-amino-3-hydroxy-4-oxobutanoate oxidoreductase from Streptomyces lasalocidi (see 2 papers)
35% identity, 88% coverage of query (202 bits)
ACDD_ASPCN / A0A2I2F284 Kynurenine 3-monooxygenase acdD; Aspcandine biosynthesis gene cluster protein D; Kynurenine 3-hydroxylase acdD; EC 1.14.13.9 from Aspergillus candidus (see paper)
32% identity, 90% coverage of query (187 bits)
Build an alignment for N515DRAFT_2874 and 36 homologs with ≥ 30% identity
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vioC / Q9S3U9 violacein synthase (EC 1.14.13.224) from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) (see 3 papers)
VIOC_CHRVO / Q9S3U9 Violacein synthase; EC 1.14.13.224 from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) (see 2 papers)
Q9S3U9 violacein synthase (EC 1.14.13.224) from Chromobacterium violaceum (see 2 papers)
29% identity, 84% coverage of query (122 bits)
AHBM2_STRPT / E2CYT2 3-amino-4-hydroxybenzoate 2-monooxygenase PtnB3; EC 1.14.13.249 from Streptomyces platensis (see 2 papers)
E2CYT2 3-amino-4-hydroxybenzoate 2-monooxygenase (EC 1.14.13.249) from Streptomyces platensis (see 2 papers)
28% identity, 78% coverage of query (78.6 bits)
AF001965 / O08453 3-hydroxy-2-methylpyridinecarboxylate dioxygenase monomer (EC 1.14.13.242) from Pseudomonas sp. MA-1 (see 5 papers)
26% identity, 77% coverage of query (71.2 bits)
ubiL1 / Q3J6F1 2-methoxy-6-(all-trans-polyprenyl)phenol 4-hydroxylase (EC 1.14.13.240) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see 3 papers)
29% identity, 85% coverage of query (70.9 bits)
ptmB3 / D8L2V9 3-amino-4-hydroxybenzoate 2-monooxygenase (EC 1.14.13.249) from Streptomyces platensis (see 3 papers)
AHBM1_STRPT / D8L2V9 3-amino-4-hydroxybenzoate 2-monooxygenase PtmB3; EC 1.14.13.249 from Streptomyces platensis (see 2 papers)
D8L2V9 3-amino-4-hydroxybenzoate 2-monooxygenase (EC 1.14.13.249) from Streptomyces platensis (see 2 papers)
28% identity, 78% coverage of query (68.2 bits)
8gsmG / A0A167KUL3 Crystal structure of vibmo1
25% identity, 71% coverage of query (66.6 bits)
rif19 / Q9AE02 rifamycin ring hydroxylase from Amycolatopsis mediterranei (see 4 papers)
28% identity, 84% coverage of query (65.9 bits)
4jy3A Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-pyridoxic acid bound form
25% identity, 77% coverage of query (65.9 bits)
4h2qA Structure of mhpco-5hn complex
25% identity, 77% coverage of query (65.9 bits)
3gmcA Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase with substrate bound
25% identity, 77% coverage of query (65.9 bits)
mlr6788 / Q988D3 3-hydroxy-2-methylpyridinecarboxylate monooxygenase monomer (EC 1.14.13.242) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 2 papers)
Q988D3 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase (EC 1.14.13.242) from Mesorhizobium loti (see 4 papers)
25% identity, 77% coverage of query (65.5 bits)
3allB / Q988D3 Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, mutant y270a
25% identity, 77% coverage of query (65.1 bits)
OPS4_BEAB2 / J4VWM7 FAD-dependent monooxygenase OpS4; Oosporein biosynthesis protein 4; EC 1.-.-.- from Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus) (Tritirachium shiotae) (see paper)
25% identity, 80% coverage of query (62.8 bits)
nat2 / F8QPH2 ansamycin ring hydroxylase from Streptomyces sp. CS (see 5 papers)
26% identity, 86% coverage of query (62.0 bits)
8aq8AAA / A0A2Y9UCL1 8aq8AAA (see paper)
30% identity, 79% coverage of query (61.2 bits)
ATNJ_ARTSZ / A0A455LLW0 FAD-dependent monooxygenase atnJ; Arthripenoid biosynthesis cluster protein J; EC 1.-.-.- from Arthrinium sp. (see paper)
25% identity, 77% coverage of query (60.8 bits)
SAT7_STACB / A0A084B9Z5 FAD-dependent monooxygenase SAT7; Satratoxin biosynthesis SC1 cluster protein 7; EC 1.-.-.- from Stachybotrys chartarum (strain CBS 109288 / IBT 7711) (Toxic black mold) (Stilbospora chartarum) (see paper)
27% identity, 76% coverage of query (60.8 bits)
6brdA / F2R776 Crystal structure of rifampin monooxygenase from streptomyces venezuelae, complexed with rifampin and fad (see paper)
27% identity, 89% coverage of query (60.8 bits)
ROX_STRVP / F2R776 Rifampicin monooxygenase; RIFMO; EC 1.14.13.211 from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
27% identity, 89% coverage of query (60.5 bits)
8x38A Crystal structure of decarboxylative vanillate 1-hydroxylase from phanerochaete chrysosporium
24% identity, 75% coverage of query (58.5 bits)
AZPB4_ASPTN / Q0CF72 FAD-dependent monooxygenase ATEG_07662; Azasperpyranone A biosynthesis cluster B protein ATEG_07662; EC 1.-.-.- from Aspergillus terreus (strain NIH 2624 / FGSC A1156) (see 2 papers)
26% identity, 82% coverage of query (54.7 bits)
A0A0A1E7Z2 salicylate 1-monooxygenase (EC 1.14.13.1) from Epichloe festucae (see paper)
23% identity, 88% coverage of query (54.7 bits)
AQDB_MYCA9 / B1MFK1 2-heptyl-3-hydroxy-4(1H)-quinolone synthase; PQS synthase; 2-heptyl-4(1H)-quinolone monooxygenase; HHQ monooxygenase; EC 1.14.13.182 from Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CCUG 20993 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543 / L948) (Mycobacterium abscessus) (see paper)
26% identity, 75% coverage of query (54.7 bits)
YETM_BACSU / O06489 Putative FAD-dependent monooxygenase YetM; EC 1.14.-.- from Bacillus subtilis (strain 168) (see paper)
26% identity, 75% coverage of query (53.5 bits)
PRHF_PENBI / A0A1E1FFL6 FAD-dependent monooxygenase prhF; Paraherquonin biosynthesis cluster protein F; EC 1.-.-.- from Penicillium brasilianum (see 2 papers)
24% identity, 76% coverage of query (52.8 bits)
6HN3M_BORBR / A0A0H3LKL4 6-hydroxynicotinate 3-monooxygenase; 6-HNA monooxygenase; EC 1.14.13.114 from Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) (Alcaligenes bronchisepticus) (see 2 papers)
24% identity, 79% coverage of query (45.4 bits)
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