Searching for up to 100 curated homologs for N515DRAFT_2924 FitnessBrowser__Dyella79:N515DRAFT_2924 (492 a.a.)
Found high-coverage hits (≥70%) to 59 curated proteins.
Removed hits that are identical to the query, leaving 58
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
5oqtA Crystal structure of a bacterial cationic amino acid transporter (cat) homologue
51% identity, 97% coverage of query (400 bits)
6f34A / Q5L1G5 Crystal structure of a bacterial cationic amino acid transporter (cat) homologue bound to arginine. (see paper)
50% identity, 99% coverage of query (397 bits)
MTRTR_BACSU / Q797A7 Methylthioribose transporter from Bacillus subtilis (strain 168) (see paper)
45% identity, 94% coverage of query (373 bits)
BCAP_BACSU / O07576 Branched-chain amino acid permease BcaP; BCAA permease from Bacillus subtilis (strain 168) (see 4 papers)
48% identity, 95% coverage of query (371 bits)
CCNA_00435 L-proline transporter from Caulobacter crescentus NA1000
41% identity, 96% coverage of query (318 bits)
Ga0059261_1577 L-glutamine and L-histidine transporter from Sphingomonas koreensis DSMZ 15582
41% identity, 98% coverage of query (290 bits)
CAAT2_ARATH / Q9ASS7 Cationic amino acid transporter 2, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 2.A.3.3.13 / Q9ASS7 Cationic amino acid transporter 2, vacuolar from Arabidopsis thaliana (see 4 papers)
39% identity, 88% coverage of query (281 bits)
CAAT4_ARATH / Q8W4K3 Cationic amino acid transporter 4, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
TC 2.A.3.3.14 / Q8W4K3 Cationic amino acid transporter 4, vacuolar from Arabidopsis thaliana (see 4 papers)
39% identity, 83% coverage of query (270 bits)
CAAT3_ARATH / Q8GYB4 Cationic amino acid transporter 3, mitochondrial from Arabidopsis thaliana (Mouse-ear cress) (see paper)
37% identity, 89% coverage of query (263 bits)
CAAT9_ARATH / Q9C5D6 Cationic amino acid transporter 9, chloroplastic from Arabidopsis thaliana (Mouse-ear cress) (see paper)
37% identity, 86% coverage of query (251 bits)
CTR1_RAT / P30823 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; EcoR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Rattus norvegicus (Rat) (see paper)
36% identity, 84% coverage of query (239 bits)
CTR1_MOUSE / Q09143 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; ERR; EcoR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Mus musculus (Mouse) (see 7 papers)
TC 2.A.3.3.1 / Q09143 System Y+ high affinity basic amino acid transporter (CAT1) (ecotropic retrovival leukemia virus receptor (ERR)) (transports arginine, lysine and ornithine; Na+-independent) from Mus musculus (Mouse) (see 2 papers)
Slc7a1 / RF|NP_031539.3 high affinity cationic amino acid transporter 1 from Mus musculus
35% identity, 84% coverage of query (237 bits)
Q16N01 ABC-type polar-amino-acid transporter (EC 7.4.2.1) from Aedes aegypti (see paper)
36% identity, 84% coverage of query (232 bits)
BCAP_LACLM / A2RHI9 Branched-chain amino acid permease BcaP; BCAA permease; BCAA transporter from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
32% identity, 94% coverage of query (231 bits)
CTR2_HUMAN / P52569 Cationic amino acid transporter 2; CAT-2; CAT2; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2 from Homo sapiens (Human) (see 3 papers)
TC 2.A.3.3.8 / P52569 Low affinity cationic amino acid transporter 2 (CAT-2) (CAT2) (Solute carrier family 7 member 2) from Homo sapiens (see 6 papers)
34% identity, 82% coverage of query (229 bits)
TC 2.A.3.3.23 / S6EX81 Branched chain amino acid (Leucine/isoleucine/valine) uptake transporter of 469 aas and 12 TMSs, BcaP or CitA from Lactococcus lactis subsp. lactis A12
32% identity, 94% coverage of query (229 bits)
CTR1_HUMAN / P30825 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Homo sapiens (Human) (see 4 papers)
TC 2.A.3.3.9 / P30825 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homologue) (Ecotropic retrovirus receptor homologue) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) from Homo sapiens (see 6 papers)
34% identity, 84% coverage of query (227 bits)
CTR2_MOUSE / P18581 Cationic amino acid transporter 2; CAT-2; CAT2; 20.5; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2; T-cell early activation protein; TEA from Mus musculus (Mouse) (see 6 papers)
34% identity, 82% coverage of query (227 bits)
TC 2.A.3.3.2 / P18581 Low affinity basic amino acid transporter (CAT2) (T-cell early activation protein (TEA)) (transports arginine, lysine and ornithine; Na+-independent) from Mus musculus (Mouse) (see 9 papers)
Slc7a2 / RF|NP_031540.2 low affinity cationic amino acid transporter 2 from Mus musculus (see paper)
34% identity, 82% coverage of query (226 bits)
CTR3_HUMAN / Q8WY07 Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3 from Homo sapiens (Human) (see paper)
TC 2.A.3.3.10 / Q8WY07 Cationic amino acid transporter 3 (CAT-3) (CAT3) (Cationic amino acid transporter y+) (Solute carrier family 7 member 3) from Homo sapiens (see 5 papers)
36% identity, 82% coverage of query (226 bits)
CAAT5_ARATH / O64759 Cationic amino acid transporter 5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.3.12 / O64759 Cationic amino acid transporter 5 from Arabidopsis thaliana (see 3 papers)
34% identity, 83% coverage of query (225 bits)
CTR3_RAT / O08812 Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3 from Rattus norvegicus (Rat) (see paper)
35% identity, 83% coverage of query (224 bits)
CTR2_CHICK / B3TP03 Cationic amino acid transporter 2; CAT-2; CAT2; cCAT-2; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2 from Gallus gallus (Chicken) (see paper)
33% identity, 83% coverage of query (220 bits)
S7A14_DANRE / B0UYF2 Probable cationic amino acid transporter; Solute carrier family 7 member 14 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
35% identity, 84% coverage of query (219 bits)
CAAT1_ARATH / Q84MA5 Cationic amino acid transporter 1; Amino acid transporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
34% identity, 84% coverage of query (218 bits)
CTR3_MOUSE / P70423 Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3 from Mus musculus (Mouse) (see paper)
TC 2.A.3.3.5 / P70423 The brain L-cationic (Arg, Lys, Orn, 2,4-diamino-n-butyrate) transporter, CAT3 (capacity of trans-stimulation by internal Arg) from Mus musculus (Mouse) (see 4 papers)
Slc7a3 / GI|123218479 Cationic amino acid transporter 3 from Mus musculus (see paper)
34% identity, 83% coverage of query (217 bits)
S7A14_HUMAN / Q8TBB6 Solute carrier family 7 member 14; Gamma-aminobutyric acid transporter SLC7A14 from Homo sapiens (Human) (see 2 papers)
35% identity, 82% coverage of query (215 bits)
S7A14_MOUSE / Q8BXR1 Solute carrier family 7 member 14; Gamma-aminobutyric acid transporter SLC7A14 from Mus musculus (Mouse) (see 2 papers)
35% identity, 86% coverage of query (213 bits)
CAAT6_ARATH / Q9LZ20 Cationic amino acid transporter 6, chloroplastic from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.3.4 / Q9LZ20 The amino acid transporter, CAT6. Mediates electrogenic transport of large neutral and cationic amino acids in preference to other amino acids. Present in lateral root primordia, flowers and seeds from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
T1E3_130 / GI|13430548 amino acid transport-like protein from Arabidopsis thaliana (see paper)
32% identity, 85% coverage of query (205 bits)
CAAT8_ARATH / Q9SHH0 Cationic amino acid transporter 8, vacuolar from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.3.11 / Q9SHH0 Cationic amino acid transporter 8, vacuolar from Arabidopsis thaliana (see 4 papers)
31% identity, 84% coverage of query (195 bits)
TC 2.A.3.3.24 / ALD51314.1 Plastidic cationic amino acid transporter, CAT, of 582 aas and 14 TMSs from Petunia x hybrida
32% identity, 95% coverage of query (180 bits)
Build an alignment for N515DRAFT_2924 and 31 homologs with ≥ 30% identity
Or download the sequences
AIMA_BACSU / Q45577 Glutamate/serine transporter AimA; Amino acid importer A from Bacillus subtilis (strain 168) (see 2 papers)
25% identity, 92% coverage of query (117 bits)
BPHYT_RS17540 L-aspartate/L-glutamate/L-glutamine:H+ symporter from Burkholderia phytofirmans PsJN
26% identity, 88% coverage of query (114 bits)
puuP / BAD88704.1 putrescine importer, partial from Escherichia coli K-12 (see paper)
23% identity, 92% coverage of query (97.4 bits)
YcjJ / b1296 putrescine:H+ symporter PuuP from Escherichia coli K-12 substr. MG1655 (see 4 papers)
puuP / P76037 putrescine:H+ symporter PuuP from Escherichia coli (strain K12) (see 2 papers)
PUUP_ECOLI / P76037 Putrescine importer PuuP from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.3.1.13 / P76037 Putrescine importer, PuuP from Escherichia coli (strain K12) (see 4 papers)
23% identity, 92% coverage of query (97.4 bits)
YeeF / b2014 putrescine:H+ symporter PlaP from Escherichia coli K-12 substr. MG1655 (see paper)
plaP / P0AA47 putrescine:H+ symporter PlaP from Escherichia coli (strain K12) (see 5 papers)
PLAP_ECOLI / P0AA47 Low-affinity putrescine importer PlaP; Putrescine low affinity permease from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.3.1.14 / P0AA47 Low-affinity putrescine importer PlaP from Escherichia coli (strain K12) (see 5 papers)
25% identity, 91% coverage of query (92.4 bits)
S7A12_MOUSE / Q8VIE6 Solute carrier family 7 member 12; Asc-type amino acid transporter 2; Asc-2; X-amino acid transporter 1; XAT-1 from Mus musculus (Mouse) (see 2 papers)
TC 2.A.3.8.14 / Q8VIE6 The Asc-type small neutral L-amino acid:H+ symport transporter-2 (Asc-2). Does not associate with 4F2hc or rBAT, but probably associates with some comparable heavy chain. Doesn't transport some substrates of Asc-1 such as α-aminoisobutyric acid and β-alanine from Mus musculus (Mouse) (see 2 papers)
Slc7a12 / RF|NP_543128.1 Asc-type amino acid transporter 2 from Mus musculus (see paper)
26% identity, 87% coverage of query (90.5 bits)
BAT1_RABIT / Q9N1R6 b(0,+)-type amino acid transporter 1; b(0,+)AT; 4F2-LC6; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Oryctolagus cuniculus (Rabbit) (see paper)
24% identity, 91% coverage of query (88.2 bits)
YhfM / b3370 fructoselysine/psicoselysine transporter from Escherichia coli K-12 substr. MG1655 (see 4 papers)
frlA / P45539 fructoselysine/psicoselysine transporter from Escherichia coli (strain K12) (see 4 papers)
FRLA_ECOLI / P45539 Probable fructoselysine/psicoselysine transporter FrlA from Escherichia coli (strain K12) (see paper)
27% identity, 84% coverage of query (87.0 bits)
GabP / b2663 4-aminobutanoate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 11 papers)
gabP / P25527 4-aminobutanoate:H+ symporter from Escherichia coli (strain K12) (see 10 papers)
GABP_ECOLI / P25527 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate carrier; 4-aminobutyrate permease; Gamma-aminobutyrate permease from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.4 / P25527 γ-aminobutyrate:H+ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005) from Escherichia coli (see 5 papers)
27% identity, 72% coverage of query (85.9 bits)
AO356_17670 L-alanine and D-alanine permease from Pseudomonas fluorescens FW300-N2C3
28% identity, 73% coverage of query (85.1 bits)
PS417_05405 L-alanine and D-alanine permease from Pseudomonas simiae WCS417
27% identity, 74% coverage of query (84.7 bits)
BAT1_HUMAN / P82251 b(0,+)-type amino acid transporter 1; b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Homo sapiens (Human) (see 16 papers)
TC 2.A.3.8.19 / P82251 B(0,+)-type amino acid transporter 1 (B(0,+)AT) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) from Homo sapiens (see 9 papers)
24% identity, 91% coverage of query (84.7 bits)
TC 2.A.3.12.4 / Q9LHN7 Golgi polyamine/paraquot uptake transporter of 478 aas, LAT4. Also called PUT2 and PAR1. Mutations give rise to paraquot resistance (Par1) both in A. thaliana and in rice. Probably present in the chloroplast membrane from Arabidopsis thaliana
25% identity, 88% coverage of query (84.3 bits)
AroR / b0112 aromatic amino acid:H+ symporter AroP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
aroP / P15993 aromatic amino acid:H+ symporter AroP from Escherichia coli (strain K12) (see 6 papers)
AROP_ECOLI / P15993 Aromatic amino acid transport protein AroP; Aromatic amino acid:H(+) symporter AroP; General aromatic amino acid permease; General aromatic transport system from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli (see 6 papers)
25% identity, 89% coverage of query (84.0 bits)
6li9B / P82251 Heteromeric amino acid transporter b0,+at-rbat complex bound with arginine (see paper)
24% identity, 91% coverage of query (84.0 bits)
BAT1_MOUSE / Q9QXA6 b(0,+)-type amino acid transporter 1; b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 from Mus musculus (Mouse) (see 2 papers)
25% identity, 89% coverage of query (82.8 bits)
AO353_16120 D-alanine and L-alanine transporter from Pseudomonas fluorescens FW300-N2E3
27% identity, 73% coverage of query (82.0 bits)
STET_BACSU / O34739 Serine/threonine exchanger SteT from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.8.12 / O34739 The Ser/Thr exchange transporter (SteT) (also transports aromatic amino acids with lower efficiency) (Reig et al., 2007). The substrate-bound state of SteT shows increased conformational flexibility and kinetic stability, enabling transport of substrate across the cell membrane (Bippes et al. 2009). TMS8 sculpts the substrate-binding site and undergoes conformational changes during the transport cycle of SteT (Bartoccioni et al., 2010). Mutations allow substrate binding but not translocation. Other mutations stabilize the protein and result in higher production levels from Bacillus subtilis (see 2 papers)
23% identity, 85% coverage of query (75.5 bits)
7nf6B / A0A6P3EL78 Ovine b0,+at-rbat heterodimer (see paper)
23% identity, 91% coverage of query (73.9 bits)
6f2wA / A8UCQ5 Bacterial asc transporter crystal structure in open to in conformation (see paper)
27% identity, 83% coverage of query (73.2 bits)
CadR / b2156 lysine:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 15 papers)
lysP / P25737 lysine:H+ symporter from Escherichia coli (strain K12) (see 13 papers)
LYSP_ECOLI / P25737 Lysine-specific permease LysP; Lysine transporter LysP; Trigger transporter LysP from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.2 / P25737 Lysine:H+ symporter. Forms a stable complex with CadC to allow lysine-dependent adaptation to acidic stress (Rauschmeier et al. 2013). The Salmonella orthologue is 95% identical to the E. coli protein and is highly specific for Lysine. Residues involved in lysine binding have been identified from Escherichia coli (see 5 papers)
lysP lysine-specific permease from Escherichia coli K12 (see 5 papers)
24% identity, 70% coverage of query (69.7 bits)
GABP_BACSU / P46349 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate permease; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis (see 4 papers)
gabP / AAC44641.1 gamma-aminobutyrate permease from Bacillus subtilis (see 2 papers)
23% identity, 72% coverage of query (61.6 bits)
SLC7A11 / Q9UPY5 cystine/glutamate transporter from Homo sapiens (see paper)
XCT_HUMAN / Q9UPY5 Cystine/glutamate transporter; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT from Homo sapiens (Human) (see 9 papers)
TC 2.A.3.8.18 / Q9UPY5 Cystine/glutamate antiporter (Amino acid transport system xCT) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) from Homo sapiens (see 7 papers)
22% identity, 74% coverage of query (53.5 bits)
7epzB Overall structure of erastin-bound xct-4f2hc complex
22% identity, 74% coverage of query (53.5 bits)
7p9uB / Q9UPY5 Cryo em structure of system xc- in complex with glutamate (see paper)
22% identity, 74% coverage of query (53.1 bits)
AAT6_CAEEL / Q22397 Amino acid transporter protein 6 from Caenorhabditis elegans (see 2 papers)
TC 2.A.3.8.27 / Q22397 Amino acid transporter 6 (AAT-6). Interacts with NRFL-1, the C. elegans NHERF orthologue to promote localization to the intestinal luminal membrane from Caenorhabditis elegans
22% identity, 89% coverage of query (51.2 bits)
RMV1_ARATH / Q9FFL1 Polyamine transporter RMV1; Protein RESISTANT TO METHYL VIOLOGEN 1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
TC 2.A.3.12.3 / Q9FFL1 Plasma membrane polyamine/paraquot uptake transporter of 490 aas, RMV1. Also called PUT3 and LAT1. Mutations give rise to partial paraquot (a toxic common herbicide that generates superoxide and reactive oxygen species (ROS)) from Arabidopsis thaliana
23% identity, 78% coverage of query (45.4 bits)
Or start over
Lawrence Berkeley National Laboratory