Sites on a Tree

 

Searching for up to 100 curated homologs for N515DRAFT_3248 FitnessBrowser__Dyella79:N515DRAFT_3248 (838 a.a.)

Found high-coverage hits (≥70%) to 56 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Ga0059261_1166 Beta-glucosidase (EC 3.2.1.21) from Sphingomonas koreensis DSMZ 15582
    51% identity, 99% coverage of query (776 bits)

AAG43575.1 cellobiase (CelA) (EC 3.2.1.21) (see protein)
    60% identity, 75% coverage of query (768 bits)

ACE84847.1 β-glucosidase / cellodextrinase D (CelD;CJA_0204) (Cel3A) (EC 3.2.1.74) (see protein)
    47% identity, 96% coverage of query (758 bits)

ACE83024.1 β-glucosidase (CJA_1497) (Cel3B) (EC 3.2.1.21) (see protein)
    49% identity, 90% coverage of query (754 bits)

ABD79509.1 β-glucosidase / cellodextrinase 3B (Sde_0245) (Ced3B) (EC 3.2.1.21|3.2.1.74) (see protein)
    47% identity, 96% coverage of query (728 bits)

ABD81757.1 β-glucosidase / cellodextrinase 3A (CedA;Sde_2497) (Ced3A) (EC 3.2.1.21|3.2.1.74) (see protein)
    49% identity, 95% coverage of query (714 bits)

ABC88234.1 exo-1,3/1,4-β-glucanase (GluA;ExoP) (EC 3.2.1.-) (see protein)
    44% identity, 97% coverage of query (670 bits)

3ut0A / Q0QJA3 Crystal structure of exo-1,3/1,4-beta-glucanase (exop) from pseudoalteromonas sp. Bb1 (see paper)
    45% identity, 90% coverage of query (666 bits)

Sama_1404 Beta-glucosidase (EC 3.2.1.21) from Shewanella amazonensis SB2B
    46% identity, 97% coverage of query (640 bits)

AIO11756.1 β-glucosidase (Bgl;GmBGL) (EC 3.2.1.21) (see protein)
    43% identity, 71% coverage of query (436 bits)

6jg1A / Q9XEI3 Crystal structure of barley exohydrolasei wildtype in complex with 4i, 4iii,4v-s-trithiocellohexaose (see paper)
    42% identity, 71% coverage of query (428 bits)

6jgaA Crystal structure of barley exohydrolasei w286f in complex with 4'- nitrophenyl thiolaminaribioside
    42% identity, 71% coverage of query (424 bits)

6jg7A Crystal structure of barley exohydrolasei w286f in complex with methyl 2-thio-beta-sophoroside
    42% identity, 71% coverage of query (424 bits)

6jg2A Crystal structure of barley exohydrolasei wildtype in complex with 4'- nitrophenyl thiolaminaribioside
    42% identity, 71% coverage of query (424 bits)

6jg6A Crystal structure of barley exohydrolasei w286a mutant in complex with methyl 6-thio-beta-gentiobioside
    42% identity, 71% coverage of query (423 bits)

AEW47937.1 β-glucosidase (A1_GH3) (EC 3.2.1.21) (see protein)
    31% identity, 70% coverage of query (273 bits)

Build an alignment

Build an alignment for N515DRAFT_3248 and 16 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

5jp0A / A7LXU3 Bacteroides ovatus xyloglucan pul gh3b with bound glucose (see paper)
    29% identity, 71% coverage of query (260 bits)

GLUA_DICDI / Q23892 Lysosomal beta glucosidase; EC 3.2.1.21 from Dictyostelium discoideum (Social amoeba) (see 2 papers)
    30% identity, 76% coverage of query (258 bits)

BGH3B_BACO1 / A7LXU3 Beta-glucosidase BoGH3B; Glycosyl hydrolase family protein 3B; BoGH3B; EC 3.2.1.21 from Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) (see paper)
    29% identity, 71% coverage of query (255 bits)

AAZ32298.1 β-glucosidase (UmBgl3A) (EC 3.2.1.21) (see protein)
    32% identity, 71% coverage of query (249 bits)

AAA74233.1 β-glucosidase (EC 3.2.1.21) (see protein)
    30% identity, 75% coverage of query (248 bits)

AFH08281.1 β-glucosidase (BGL9;Bgl11) (EC 3.2.1.21) (see protein)
    31% identity, 73% coverage of query (237 bits)

AAB62870.1 β-glucosidase (EC 3.2.1.21) (see protein)
    30% identity, 76% coverage of query (228 bits)

3u48B From soil to structure: a novel dimeric family 3-beta-glucosidase isolated from compost using metagenomic analysis
    30% identity, 70% coverage of query (222 bits)

AFM44649.1 β-xylosidase (ORF0541) (Xyl3A) (EC 3.2.1.37) (see protein)
    29% identity, 70% coverage of query (214 bits)

5xxmA / Q8A1U1 Crystal structure of gh3 beta-glucosidase from bacteroides thetaiotaomicron in complex with gluconolactone (see paper)
    29% identity, 72% coverage of query (214 bits)

BT3567 periplasmic beta-1,2-glucosidase / beta-1,3-glucosidase from Bacteroides thetaiotaomicron VPI-5482
    29% identity, 72% coverage of query (214 bits)

5xxnA Crystal structure of mutant (d286n) beta-glucosidase from bacteroides thetaiotaomicron in complex with sophorose
    29% identity, 72% coverage of query (213 bits)

AEW47970.1 β-glucosidase (H1_GH3) (EC 3.2.1.21) (see protein)
    29% identity, 74% coverage of query (211 bits)

ACM61424.1 β-xylosidase (Cb2487;Cb1172;CbXyl3A;Athe_2354) (Xyl3A) (EC 3.2.1.37) (see protein)
    27% identity, 74% coverage of query (205 bits)

8c7fA / Q9WXT1 Crystal structure of beta-xylosidase mutant (d281n, e517q) from thermotoga maritima in complex with xylopentaose
    27% identity, 70% coverage of query (204 bits)

AAD35170.1 β-xylosidase (XloA;TM0076) (Xyl3) (EC 3.2.1.37) (see protein)
    27% identity, 70% coverage of query (204 bits)

7zb3A Crystal structure of beta-xylosidase from thermotoga maritima in complex with xylohexaose hydrolysed to xylobiose
    27% identity, 70% coverage of query (204 bits)

7zdyW Crystal structure of beta-xylosidase from thermotoga maritima in complex with methyl-beta-d-xylopyranoside
    27% identity, 70% coverage of query (204 bits)

7zgzX / Q9WXT1 Crystal structure of beta-xylosidase from thermotoga maritima in complex with methyl-beta-d-xylopyranoside hydrolysed to xylose
    28% identity, 70% coverage of query (203 bits)

5tf0A / B3C777 Crystal structure of glycosil hydrolase family 3 n-terminal domain protein from bacteroides intestinalis
    29% identity, 70% coverage of query (202 bits)

AAA60495.1 β-glucosidase (BglX) (EC 3.2.1.21) (see protein)
    28% identity, 72% coverage of query (200 bits)

AAF43783.1 β-xylosidase / α-L-arabinofuranosidase (XarB) (EC 3.2.1.37|3.2.1.55) (see protein)
    26% identity, 71% coverage of query (199 bits)

AFY97406.1 β-xylosidase (FgXyl3A) (Xyl3A) (EC 3.2.1.37) (see protein)
    28% identity, 74% coverage of query (199 bits)

6r5iA / Q9I311 The crystal structure of the glycoside hydrolase bglx from p. Aeruginosa (see paper)
    29% identity, 70% coverage of query (193 bits)

6r5nA The crystal structure of glycoside hydrolase bglx from p. Aeruginosa in complex with 1-deoxynojirimycin
    29% identity, 70% coverage of query (193 bits)

6r5vA The crystal structure of glycoside hydrolase bglx inactive mutant d286n from p. Aeruginosa in complex with xylotriose
    29% identity, 70% coverage of query (192 bits)

6r5oA The crystal structure the glycoside hydrolase bglx inactive mutant d286n from p. Aeruginosa in complex with two glucose molecules
    29% identity, 70% coverage of query (192 bits)

6r5tA The crystal structure of glycoside hydrolase bglx inactive mutant d286n from p. Aeruginosa in complex with lactose
    29% identity, 70% coverage of query (191 bits)

4zobA Crystal structure of beta-glucosidase from listeria innocua in complex with gluconolactone
    29% identity, 71% coverage of query (191 bits)

Q92AS9 beta-glucosidase (EC 3.2.1.21) from Listeria innocua Clip11262 (see paper)
CAC97071.1 β-1,2-glucosidase / β-1,3-glucosidase (Lin1840) (EC 3.2.1.-|3.2.1.-) (see protein)
    29% identity, 71% coverage of query (189 bits)

AEH50242.1 β-xylosidase (XynB3;Theth_0138) (EC 3.2.1.37) (see protein)
    27% identity, 71% coverage of query (189 bits)

4zo6B / Q92AS9 Crystal structure of mutant (d270a) beta-glucosidase from listeria innocua in complex with cellobiose (see paper)
    29% identity, 71% coverage of query (186 bits)

4zo7A Crystal structure of mutant (d270a) beta-glucosidase from listeria innocua in complex with gentiobiose
    29% identity, 71% coverage of query (186 bits)

4zoaA Crystal structure of beta-glucosidase from listeria innocua in complex with isofagomine
    28% identity, 71% coverage of query (186 bits)

AGU12029.1 c84_2 (EC 3.2.1.21|3.2.1.37) (see protein)
    28% identity, 76% coverage of query (172 bits)

AMK07510.1 β-xylosidase (XylB) (EC 3.2.1.37) (see protein)
    26% identity, 73% coverage of query (168 bits)

AGU11176.1 c53_8 (EC 3.2.1.37) (see protein)
    27% identity, 70% coverage of query (153 bits)

AAO42605.1 β-xylosidase (Bxl2) (EC 3.2.1.37) (see protein)
    27% identity, 70% coverage of query (144 bits)

ADD92015.1 β-xylosidase (Orf0911;00911-GPBOY) (Xyl3B) (EC 3.2.1.37) (see protein)
    25% identity, 73% coverage of query (140 bits)

BXL4_ARATH / Q9FLG1 Beta-D-xylosidase 4; AtBXL4; EC 3.2.1.37 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9FLG1 xylan 1,4-beta-xylosidase (EC 3.2.1.37) from Arabidopsis thaliana (see paper)
BAB11424.1 β-xylosidase (Xyl4;AtBXL4;At5g64570) (EC 3.2.1.37) (see protein)
    26% identity, 71% coverage of query (139 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory