Sites on a Tree

 

Searching for up to 100 curated homologs for N515DRAFT_3479 FitnessBrowser__Dyella79:N515DRAFT_3479 (210 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

3m3mA / Q4K8I0 Crystal structure of glutathione s-transferase from pseudomonas fluorescens [pf-5]
    41% identity, 89% coverage of query (141 bits)

4hz2B / A7ILT8 Crystal structure of glutathione s-transferase xaut_3756 (target efi- 507152) from xanthobacter autotrophicus py2
    38% identity, 92% coverage of query (121 bits)

4ecjA Crystal structure of glutathione s-transferase prk13972 (target efi- 501853) from pseudomonas aeruginosa pacs2 complexed with glutathione
    36% identity, 92% coverage of query (95.1 bits)

6tahB 6tahB
    35% identity, 92% coverage of query (89.0 bits)

YfcG / b2302 disulfide reductase from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yfcG / P77526 disulfide bond oxidoreductase YfcG from Escherichia coli (strain K12) (see 4 papers)
YFCG_ECOLI / P77526 Disulfide-bond oxidoreductase YfcG; GSH-dependent disulfide-bond oxidoreductase YfcG; GST N1-1; GST-like protein YfcG; Organic hydroperoxidase; EC 1.8.4.-; EC 1.11.1.- from Escherichia coli (strain K12) (see 2 papers)
    32% identity, 92% coverage of query (89.0 bits)

3gx0A Crystal structure of gsh-dependent disulfide bond oxidoreductase
    32% identity, 92% coverage of query (89.0 bits)

Build an alignment

Build an alignment for N515DRAFT_3479 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

4l8eA / D3VKV1 Crystal structure of a glutathione transferase family member from xenorhabdus nematophila, target efi-507418, with two gsh per subunit
    29% identity, 90% coverage of query (86.3 bits)

8ai8A / Q55139 Crystal structure of glutathione transferase chi 1 from synechocystis sp. Pcc 6803 in complex with glutathione (see paper)
    36% identity, 90% coverage of query (85.1 bits)

7pkaA Synechocystis sp. Pcc6803 glutathione transferase chi 1, gsoh bound
    36% identity, 90% coverage of query (85.1 bits)

5hfkA / P77526 Crystal structure of a glutathione s-transferase protein from escherichia coli och 157:h7 str. Sakai (ecs3186, target efi-507414) with bound glutathione
    32% identity, 92% coverage of query (84.7 bits)

isoJ / CAB55824.1 glutathione S-transferase from Rhodococcus sp. AD45 (see paper)
    33% identity, 94% coverage of query (84.7 bits)

4nhzH / A5EI34 Crystal structure of glutathione transferase bbta-3750 from bradyrhizobium sp., Target efi-507290, with one glutathione bound
    33% identity, 89% coverage of query (83.6 bits)

4e8hB / O61996 Structural of bombyx mori glutathione transferase bmgstd1 complex with gtt
    31% identity, 90% coverage of query (83.2 bits)

Q2G4B4 glutathione transferase (subunit 2/2) (EC 2.5.1.18) from Novosphingobium aromaticivorans (see paper)
    27% identity, 90% coverage of query (82.4 bits)

ndmE / R9TPE4 glutathione-S-transferase NdmE (EC 1.14.13.128) from Pseudomonas putida (see paper)
    34% identity, 97% coverage of query (81.6 bits)

GST1C_ANOGA / Q93112 Glutathione S-transferase 1, isoform C; AgGst1-alpha; Aggst1-5; DDT-dehydrochlorinase; GST class-theta; EC 2.5.1.18; EC 4.5.1.1 from Anopheles gambiae (African malaria mosquito) (see paper)
    33% identity, 78% coverage of query (79.0 bits)

1jlvA / Q7KIF2 Anopheles dirus species b glutathione s-transferases 1-3 (see paper)
    34% identity, 78% coverage of query (78.6 bits)

GSTd1-5 / CAB03592.1 GSTD1-5 protein from Anopheles gambiae (see 2 papers)
    33% identity, 78% coverage of query (77.4 bits)

4f0cA / I7B368 Crystal structure of the glutathione transferase ure2p5 from phanerochaete chrysosporium (see paper)
    28% identity, 80% coverage of query (75.9 bits)

3wywB / Q8N0B3 Structural characterization of catalytic site of a nilaparvata lugens delta-class glutathione transferase (see paper)
    33% identity, 76% coverage of query (75.9 bits)

Q8N0B3 glutathione transferase (EC 2.5.1.18) from Nilaparvata lugens (see paper)
    33% identity, 76% coverage of query (75.5 bits)

gst3b / CAB38119.1 Glutathione transferase III(b) from Zea mays (see paper)
    31% identity, 92% coverage of query (74.3 bits)

4mzwA / A3CNR0 Crystal structure of nu-class glutathione transferase yghu from streptococcus sanguinis sk36, complex with glutathione disulfide, target efi-507286
    28% identity, 89% coverage of query (73.9 bits)

4f0bA / I7A570 Crystal structure of the glutathione transferase ure2p1 from phanerochaete chrysosporium. (see paper)
    30% identity, 88% coverage of query (73.6 bits)

gst3a / CAB38118.1 Glutathione transferase III(a) from Zea mays (see paper)
    31% identity, 92% coverage of query (73.2 bits)

Q60GK5 glutathione transferase (EC 2.5.1.18) from Bombyx mori (see paper)
    32% identity, 78% coverage of query (72.4 bits)

5f06A / U5GTL0 Crystal structure of glutathione transferase f7 from populus trichocarpa (see paper)
    28% identity, 92% coverage of query (72.4 bits)

5echB / Q8L7C9 Crystal structure of fin219-fip1 complex with ja and atp (see paper)
    26% identity, 78% coverage of query (72.4 bits)

GSTUK_ARATH / Q8L7C9 Glutathione S-transferase U20; AtGSTU20; FIN219-interacting protein 1; GST class-tau member 20; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    26% identity, 78% coverage of query (72.4 bits)

GSTD3_DROME / Q9VG97 Inactive glutathione S-transferase D3 from Drosophila melanogaster (Fruit fly) (see paper)
    27% identity, 81% coverage of query (72.0 bits)

4ikhA / Q4KED9 Crystal structure of a glutathione transferase family member from pseudomonas fluorescens pf-5, target efi-900003, with two glutathione bound
    33% identity, 75% coverage of query (71.2 bits)

Q8RW03 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    33% identity, 77% coverage of query (70.9 bits)

GSTT2_ANOGA / Q94999 Glutathione S-transferase 2; Aggst1-2; GST class-theta; EC 2.5.1.18 from Anopheles gambiae (African malaria mosquito) (see paper)
    31% identity, 92% coverage of query (70.5 bits)

gstA theta class glutathione S-transferase; EC 2.5.1.18 from Emericella nidulans (see paper)
    28% identity, 92% coverage of query (70.5 bits)

Q8RW04 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    33% identity, 77% coverage of query (70.1 bits)

4mf6A / B1FXZ2 Crystal structure of glutathione transferase bgramdraft_1843 from burkholderia graminis, target efi-507289, with two glutathione molecules bound per one protein subunit
    33% identity, 79% coverage of query (70.1 bits)

GSTF3_MAIZE / P04907 Glutathione S-transferase 3; GST class-phi member 3; GST-III; EC 2.5.1.18 from Zea mays (Maize) (see 2 papers)
    31% identity, 92% coverage of query (68.9 bits)

Q3MUP2 glutathione transferase (EC 2.5.1.18) from Hordeum vulgare (see paper)
    31% identity, 77% coverage of query (68.9 bits)

4zb6D / A0A0R4I980 Crystal structure of glutathione transferase ure2p4 from phanerochaete chrysosporium in complex with oxidized glutathione. (see paper)
    28% identity, 80% coverage of query (68.9 bits)

gst1 / GB|AAF21054.1 glutathione S-transferase Gst1; EC 2.5.1.18 from Schizosaccharomyces pombe (see 2 papers)
    29% identity, 79% coverage of query (68.9 bits)

Q8RW02 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    32% identity, 77% coverage of query (68.6 bits)

4zb8A / A0A0R4I981 Crystal structure of the glutathione transferase ure2p6 from phanerochaete chrysosporium in complex with oxidized glutathione. (see paper)
    28% identity, 80% coverage of query (68.6 bits)

4zbaA / A0A0R4I985 Crystal structure of the glutathione transferase ure2p8 from phanerochaete chrysosporium with oxidized glutathione. (see paper)
    29% identity, 78% coverage of query (68.6 bits)

4zbdA Crystal structure of the glutathione transferase ure2p6 from phanerochaete chrysosporium in complex with glutathione reduced by x- ray irradiation at 100k
    28% identity, 80% coverage of query (68.6 bits)

4zbbA Crystal structure of the glutathione transferase ure2p8 from phanerochaete chrysosporium complexed with glutathionyl-s- dinitrobenzene.
    29% identity, 78% coverage of query (68.6 bits)

GST1D_ANOGA / Q93113 Glutathione S-transferase 1, isoform D; AgGst1-alpha; Aggst1-1; Aggst1-6; Aggst2-1; DDT-dehydrochlorinase; GST class-theta; EC 2.5.1.18; EC 4.5.1.1 from Anopheles gambiae (African malaria mosquito) (see 3 papers)
1pn9A / Q93113 Crystal structure of an insect delta-class glutathione s-transferase from a ddt-resistant strain of the malaria vector anopheles gambiae (see paper)
GSTd1-6 / CAB03593.1 GSTD1-6 protein, partial from Anopheles gambiae (see 2 papers)
    31% identity, 78% coverage of query (68.2 bits)

A4LAG9 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    27% identity, 86% coverage of query (67.8 bits)

GSTD7_DROME / Q9VG93 Glutathione S-transferase D7; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    26% identity, 92% coverage of query (67.8 bits)

CH_124240 putative glutathione S-transferase [Botryotinia fuckeliana] from Magnaporthe grisea 70-15 (see paper)
    24% identity, 87% coverage of query (67.8 bits)

XYLK / AAC44159.1 glutathione S-transferase from Cycloclasticus oligotrophus (see paper)
    30% identity, 72% coverage of query (67.8 bits)

7rhpA / A0A7M7GUY7 Crystal structure of honeybee (apis mellifera) glutathione s- transferase amgstd1 (see paper)
    28% identity, 81% coverage of query (67.4 bits)

MAAI2_DROME / Q9VHD2 Probable maleylacetoacetate isomerase 2; MAAI 2; Glutathione S-transferase zeta 2; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    31% identity, 84% coverage of query (67.0 bits)

Q8DMB4 glutathione transferase (EC 2.5.1.18) from Thermosynechococcus vestitus (see paper)
    31% identity, 92% coverage of query (67.0 bits)

A0AEF0 glutathione transferase (EC 2.5.1.18) from Phytophthora infestans (see paper)
    29% identity, 92% coverage of query (66.6 bits)

D2WL48 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    25% identity, 98% coverage of query (66.2 bits)

4ielB / Q0B681 Crystal structure of a glutathione s-transferase family protein from burkholderia ambifaria, target efi-507141, with bound glutathione
    28% identity, 98% coverage of query (66.2 bits)

1r5aA / Q9GQG7 Glutathione s-transferase (see paper)
    30% identity, 78% coverage of query (65.1 bits)

5o00A Ure2p5 from phanerochaete chrysosporium cocrystallized with 1-(s- glutathionyl)-2,4-dinitrobenzene.
    27% identity, 80% coverage of query (65.1 bits)

3ergA / Q12390 Crystal structure of gtt2 from saccharomyces cerevisiae in complex with glutathione sulfnate (see paper)
    30% identity, 79% coverage of query (64.7 bits)

4kh7B / Q8Z859 Crystal structure of a glutathione transferase family member from salmonella enterica ty2, target efi-507262, with bound glutathione
    28% identity, 92% coverage of query (64.7 bits)

3ibhA Crystal structure of saccharomyces cerevisiae gtt2 in complex with glutathione
    30% identity, 79% coverage of query (64.7 bits)

4puaA Crystal structure of glutathione transferase yghu from streptococcus pneumoniae atcc 700669, complexed with glutathione, target efi-507284
    26% identity, 89% coverage of query (64.3 bits)

3uarA / Q60CN1 Crystal structure of glutathione transferase (target efi-501774) from methylococcus capsulatus str. Bath with gsh bound
    27% identity, 92% coverage of query (64.3 bits)

GTT2 / Q12390 glutathione transferase 2 monomer (EC 2.5.1.18) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 13 papers)
GST2_YEAST / Q12390 Glutathione S-transferase 2; GST-II; EC 2.5.1.18 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    30% identity, 78% coverage of query (64.3 bits)

4naxA / A5W1A6 Crystal structure of glutathione transferase pput_1760 from pseudomonas putida, target efi-507288, with one glutathione disulfide bound per one protein subunit
    30% identity, 91% coverage of query (64.3 bits)

A1YW90 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    26% identity, 79% coverage of query (63.9 bits)

4pnfB / Q7JZM3 Glutathione s-transferase from drosophila melanogaster - isozyme e6 (see paper)
    30% identity, 91% coverage of query (63.5 bits)

4i97A / R4S8C5 The crystal structure of glutathione s-transferase sniggstd1a from scaptomyza nigrita in complex with glutathione
    32% identity, 75% coverage of query (63.5 bits)

1v2aB / Q9BHB0 Glutathione s-transferase 1-6 from anopheles dirus species b (see paper)
    30% identity, 70% coverage of query (63.5 bits)

4gf0A / A3STM0 Crystal structure of glutahtione transferase homolog from sulfitobacter, target efi-501084, with bound glutathione
    27% identity, 91% coverage of query (62.8 bits)

5j4uA / B9I0G5 Crystal structure of a glutathione s-transferase ptgstu30 from populus trichocarpa in complex with gsh
    26% identity, 79% coverage of query (62.8 bits)

GST1 / AAA29287.1 glutathione transferase from Lucilia cuprina (see paper)
    32% identity, 73% coverage of query (62.8 bits)

4g9hA / Q8D0L3 Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione
    27% identity, 72% coverage of query (62.8 bits)

GSTD2_DROME / Q9VG98 Glutathione S-transferase D2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
Q9VG98 glutathione transferase (EC 2.5.1.18) from Drosophila melanogaster (see paper)
    28% identity, 90% coverage of query (62.8 bits)

3c8eA / Q46845 Crystal structure analysis of yghu from e. Coli (see paper)
    29% identity, 91% coverage of query (62.4 bits)

YghU / b2989 disulfide reductase / organic hydroperoxide reductase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
yghU / Q46845 disulfide reductase / organic hydroperoxide reductase from Escherichia coli (strain K12) (see 3 papers)
YGHU_ECOLI / Q46845 Disulfide-bond oxidoreductase YghU; GSH-dependent disulfide-bond oxidoreductase YghU; GST N2-2; Organic hydroperoxidase; EC 1.8.4.-; EC 1.11.1.- from Escherichia coli (strain K12) (see paper)
    29% identity, 91% coverage of query (62.4 bits)

P42860 glutathione transferase (EC 2.5.1.18) from Lucilia cuprina (see paper)
    31% identity, 73% coverage of query (62.4 bits)

GSTD4_DROME / Q9VG96 Glutathione S-transferase D4; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    30% identity, 85% coverage of query (62.4 bits)

GST1B_ANOGA / O77473 Glutathione S-transferase 1, isoform B; AgGst1-alpha; Aggst1-4; GST class-theta; EC 2.5.1.18 from Anopheles gambiae (African malaria mosquito) (see paper)
    31% identity, 75% coverage of query (62.0 bits)

3gh6A / Q9VGA1 Crystal structure of glutathione transferase dmgstd10 from drosophila melanogaster, in complex with glutathione (see paper)
    31% identity, 73% coverage of query (61.6 bits)

4ri6A / A9PHH6 Crystal structure of poplar glutathione transferase f1 (see paper)
    27% identity, 70% coverage of query (61.2 bits)

2x64B / Q9PE18 Glutathione-s-transferase from xylella fastidiosa
    30% identity, 74% coverage of query (61.2 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    28% identity, 84% coverage of query (60.8 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    28% identity, 84% coverage of query (60.8 bits)

GSTF9_ARATH / O80852 Glutathione S-transferase F9; AtGSTF9; AtGSTF7; GST class-phi member 9; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    25% identity, 80% coverage of query (59.7 bits)

6f01B Arabidopsis thaliana gstf9, gso3 and gsoh bound
    25% identity, 80% coverage of query (59.3 bits)

6ezyB / O80852 Arabidopsis thaliana gstf9, gsh and gsoh bound (see paper)
    25% identity, 80% coverage of query (59.3 bits)

1pmtA / P15214 Glutathione transferase from proteus mirabilis (see paper)
    27% identity, 72% coverage of query (59.3 bits)

3f63A / Q9GN60 Crystal structure of a delta class gst (adgstd4-4) from anopheles dirus, in complex with s-hexyl glutathione (see paper)
    30% identity, 76% coverage of query (59.3 bits)

GST_PROMI / P15214 Glutathione S-transferase GST-6.0; GST B1-1; EC 2.5.1.18 from Proteus mirabilis (see paper)
    27% identity, 72% coverage of query (59.3 bits)

4topA Glycine max glutathione transferase
    25% identity, 95% coverage of query (58.9 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    26% identity, 89% coverage of query (58.5 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    26% identity, 89% coverage of query (58.2 bits)

5zwpA / P28338 Crystal structure of the delta-class glutathione transferase from musca domestica (see paper)
    29% identity, 75% coverage of query (58.2 bits)

A1ZB72 glutathione transferase (EC 2.5.1.18) from Drosophila melanogaster (see paper)
4pngB / A1ZB72 Glutathione s-transferase from drosophila melanogaster - isozyme e7 (see paper)
    28% identity, 88% coverage of query (58.2 bits)

6ep7B / Q9M9F1 Arabidopsis thaliana gstu23, gsh bound (see paper)
    26% identity, 96% coverage of query (58.2 bits)

5g5aA / Q9SHH7 Glutathione transferase u25 from arabidopsis thaliana in complex with glutathione disulfide
    25% identity, 79% coverage of query (58.2 bits)

GSTD1_DROME / P20432 Glutathione S-transferase D1; DDT-dehydrochlorinase; EC 2.5.1.18; EC 4.5.1.1 from Drosophila melanogaster (Fruit fly) (see 2 papers)
    29% identity, 75% coverage of query (58.2 bits)

3makA / P20432 Crystal structure of glutathione transferase dmgstd1 from drosophila melanogaster, in complex with glutathione (see paper)
    29% identity, 75% coverage of query (58.2 bits)

3vwxC / Q9U795 Structural analysis of an epsilon-class glutathione s-transferase from housefly, musca domestica (see paper)
    27% identity, 91% coverage of query (57.8 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory