Searching for up to 100 curated homologs for N515DRAFT_3588 FitnessBrowser__Dyella79:N515DRAFT_3588 (308 a.a.)
Found high-coverage hits (≥70%) to 48 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DRRA_STRPE / P32010 Daunorubicin/doxorubicin resistance ATP-binding protein DrrA; EC 7.6.2.- from Streptomyces peucetius (see 2 papers)
P32010 ABC-type xenobiotic transporter (EC 7.6.2.2) from Streptomyces peucetius (see paper)
TC 3.A.1.105.1 / P32010 DrrA, component of Daunorubicin, doxorubicin etc. (multidrug resistance) exporter, DrrAB from Streptomyces peucetius (see 2 papers)
40% identity, 83% coverage of query (160 bits)
LNRL_BACSU / P94440 Linearmycin resistance ATP-binding protein LnrL; EC 7.6.2.- from Bacillus subtilis (strain 168) (see 2 papers)
35% identity, 93% coverage of query (154 bits)
TC 3.A.1.105.2 / Q53716 OleC4, component of Oleandomycin (drug resistance) exporter from Streptomyces antibioticus (see paper)
39% identity, 70% coverage of query (152 bits)
sagG / GI|23305059 ABC transporter, ATP-binding protein SagG from Streptococcus iniae (see paper)
32% identity, 93% coverage of query (148 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
35% identity, 70% coverage of query (141 bits)
YbhF / b0794 ABC exporter ATP binding subunit YbhF (EC 7.6.2.2) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
ybhF / P0A9U1 ABC exporter ATP binding subunit YbhF (EC 7.6.2.2) from Escherichia coli (strain K12) (see 6 papers)
YBHF_ECOLI / P0A9U1 Probable multidrug ABC transporter ATP-binding protein YbhF from Escherichia coli (strain K12) (see paper)
ybhF / MB|P0A9U1 uncharacterized ABC transporter ATP-binding protein ybhF from Escherichia coli K12 (see paper)
35% identity, 72% coverage of query (140 bits)
TC 3.A.1.105.8 / Q7UE58 ABC-type multidrug transport system, ATPase component, component of ABC-2 transporter from Rhodopirellula baltica (strain SH1)
34% identity, 95% coverage of query (139 bits)
ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
36% identity, 70% coverage of query (126 bits)
YhiG / b3486 ribosome-associated ATPase from Escherichia coli K-12 substr. MG1655 (see 13 papers)
RBBA_ECOLI / P37624 Ribosome-associated ATPase; Ribosomal bound ATPase from Escherichia coli (strain K12) (see 5 papers)
yhiH / RF|YP_026225 uncharacterized ABC transporter ATP-binding protein yhiH from Escherichia coli K12 (see paper)
35% identity, 77% coverage of query (126 bits)
Build an alignment for N515DRAFT_3588 and 9 homologs with ≥ 30% identity
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TC 3.A.1.142.1 / Q8DNB9 Putative uncharacterized protein ABC-NBD, component of Glycolipid translocase (flippase) Spr1816/Spr1817 (R.Hakenbeck, personal communication) from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
28% identity, 94% coverage of query (125 bits)
ABCA9_HUMAN / Q8IUA7 ATP-binding cassette sub-family A member 9; EC 7.6.2.- from Homo sapiens (Human) (see paper)
TC 3.A.1.211.16 / Q8IUA7 ATP-binding cassette sub-family A member 9, ABCA9 of 1624 aas. May play a role in monocyte differentiation and lipid homeostasis. Expressed in fetal tissues with highest expression in fetal heart and kidney. Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages from Homo sapiens
33% identity, 73% coverage of query (124 bits)
ABCA2_HUMAN / Q9BZC7 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Homo sapiens (Human) (see 10 papers)
38% identity, 70% coverage of query (120 bits)
ABCA6_HUMAN / Q8N139 ATP-binding cassette sub-family A member 6; EC 7.6.2.- from Homo sapiens (Human) (see 3 papers)
TC 3.A.1.211.15 / Q8N139 ATP-binding cassette sub-family A member 6, ABCA6 of 1617 aas. This transporter may play a role in macrophage lipid homeostasis. It is up-regulated during monocyte differentiation into macrophages but down-regulated by cholesterol loading of macrophages from Homo sapiens
35% identity, 70% coverage of query (120 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
37% identity, 71% coverage of query (119 bits)
7roqA / O95477 Alternative structure of human abca1
31% identity, 89% coverage of query (117 bits)
7w02A / Q99758 Cryo-em structure of atp-bound abca3 (see paper)
37% identity, 71% coverage of query (117 bits)
7o12B / P19844 Abc transporter nosdfy, amppnp-bound in gdn (see paper)
35% identity, 75% coverage of query (112 bits)
7tbyA / O95477 The structure of human abca1 in nanodisc (see paper)
30% identity, 86% coverage of query (112 bits)
1g291 / Q9YGA6 Malk (see paper)
33% identity, 70% coverage of query (111 bits)
7o17B Abc transporter nosdfy e154q, atp-bound in lipid nanodisc
34% identity, 75% coverage of query (111 bits)
6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
29% identity, 72% coverage of query (101 bits)
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
32% identity, 70% coverage of query (100 bits)
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
32% identity, 70% coverage of query (100 bits)
6b89A E. Coli lptb in complex with adp and novobiocin
32% identity, 70% coverage of query (100 bits)
4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
32% identity, 70% coverage of query (100 bits)
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
32% identity, 70% coverage of query (100 bits)
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
32% identity, 70% coverage of query (100 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
29% identity, 71% coverage of query (99.8 bits)
6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
31% identity, 70% coverage of query (99.4 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
31% identity, 73% coverage of query (98.2 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
29% identity, 70% coverage of query (93.6 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
29% identity, 70% coverage of query (93.6 bits)
2olkA Abc protein artp in complex with adp-beta-s
29% identity, 70% coverage of query (93.6 bits)
2oljA Abc protein artp in complex with adp/mg2+
29% identity, 70% coverage of query (93.6 bits)
7ahhC Opua inhibited inward-facing, sbd docked
25% identity, 82% coverage of query (86.7 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
25% identity, 82% coverage of query (86.7 bits)
ABCG1_HUMAN / P45844 ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; White protein homolog; EC 7.6.2.- from Homo sapiens (Human) (see 11 papers)
TC 3.A.1.204.12 / P45844 The intracellular sterol transporter, ABCG1 from Homo sapiens (see 13 papers)
26% identity, 78% coverage of query (84.7 bits)
7oz1A Cryo-em structure of abcg1 e242q mutant with atp and cholesteryl hemisuccinate bound
26% identity, 77% coverage of query (81.6 bits)
7r8eA / P45844 The structure of human abcg1 e242q complexed with atp (see paper)
26% identity, 76% coverage of query (80.5 bits)
8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
27% identity, 76% coverage of query (73.9 bits)
5d3mB Folate ecf transporter: amppnp bound state
27% identity, 76% coverage of query (73.9 bits)
6tejB / A0A100XE85 Structure of apo irtab devoid sid in complex with sybody syb_nl5 (see paper)
31% identity, 71% coverage of query (73.9 bits)
8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
26% identity, 76% coverage of query (72.8 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
27% identity, 71% coverage of query (72.0 bits)
2ixfA / P36370 Crystal structure of the atpase domain of tap1 with atp (d645q, q678h mutant) (see paper)
32% identity, 74% coverage of query (69.3 bits)
P9WQK5 Uncharacterized ABC transporter ATP-binding protein Rv0073 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
27% identity, 95% coverage of query (68.9 bits)
TAP1_RAT / P36370 Antigen peptide transporter 1; APT1; ATP-binding cassette sub-family B member 2; Peptide transporter TAP1; EC 7.4.2.14 from Rattus norvegicus (Rat) (see 2 papers)
P36370 ABC-type antigen peptide transporter (subunit 2/2) (EC 7.4.2.14) from Rattus norvegicus (see 6 papers)
32% identity, 74% coverage of query (65.1 bits)
7dv5U / O95342 Human bile salt exporter abcb11 in complex with taurocholate (see paper)
27% identity, 71% coverage of query (53.1 bits)
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Lawrence Berkeley National Laboratory