Searching for up to 100 curated homologs for N515DRAFT_3778 FitnessBrowser__Dyella79:N515DRAFT_3778 (337 a.a.)
Found high-coverage hits (≥70%) to 50 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ACMSD / Q8TDX5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Homo sapiens (see 2 papers)
ACMSD_HUMAN / Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Homo sapiens (Human) (see 2 papers)
Q8TDX5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Homo sapiens (see 5 papers)
50% identity, 99% coverage of query (364 bits)
4ofcA / Q8TDX5 2.0 angstroms x-ray crystal structure of human 2-amino-3- carboxymuconate-6-semialdehye decarboxylase (see paper)
50% identity, 99% coverage of query (364 bits)
ACMSD_MOUSE / Q8R519 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Mus musculus (Mouse) (see paper)
Q8R519 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Mus musculus (see paper)
51% identity, 97% coverage of query (363 bits)
7pwyA Structure of human dimeric acmsd in complex with the inhibitor tes- 1025
51% identity, 99% coverage of query (363 bits)
4ih3A 2.5 angstroms x-ray crystal structure of of human 2-amino-3- carboxymuconate-6-semialdehyde decarboxylase in complex with dipicolinic acid
51% identity, 97% coverage of query (362 bits)
2wm1A The crystal structure of human alpha-amino-beta-carboxymuconate- epsilon-semialdehyde decarboxylase in complex with 1,3- dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis
51% identity, 97% coverage of query (362 bits)
ACMSD_RAT / Q8R5M5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Rattus norvegicus (Rat) (see 2 papers)
Q8R5M5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Rattus norvegicus (see 3 papers)
51% identity, 97% coverage of query (359 bits)
7pwyC / Q8TDX5 Structure of human dimeric acmsd in complex with the inhibitor tes- 1025 (see paper)
47% identity, 97% coverage of query (307 bits)
nbaD / A4IT47 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) from Geobacillus thermodenitrificans (strain NG80-2) (see paper)
42% identity, 97% coverage of query (277 bits)
nbaD / Q83V25 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase (EC 4.1.1.45) from Pseudomonas fluorescens (see paper)
Q83V25 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Pseudomonas fluorescens (see 2 papers)
nbaD / BAC65312.1 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase from Pseudomonas fluorescens (see paper)
39% identity, 97% coverage of query (230 bits)
7k13C Acmsd in complex with diflunisal derivative 14
39% identity, 97% coverage of query (230 bits)
7k12A Acmsd in complex with diflunisal
39% identity, 97% coverage of query (230 bits)
2hbvA Crystal structure of alpha-amino-beta-carboxymuconate-epsilon- semialdehyde-decarboxylase (acmsd)
39% identity, 97% coverage of query (230 bits)
4eraA / Q83V25 Evidence for a dual role of an active site histidine in alpha-amino- beta-carboxymuconate-epsilon-semialdehyde decarboxylase (see paper)
38% identity, 97% coverage of query (228 bits)
4ergA Evidence for a dual role of an active site histidine in alpha-amino- beta-carboxymuconate-epsilon-semialdehyde decarboxylase
38% identity, 97% coverage of query (228 bits)
praH / C4TP08 5-carboxy-2-hydroxymuconate-6-semialdehyde decarboxylase from Paenibacillus sp. JJ-1b (see 3 papers)
praH / BAH79106.1 5-carboxy-2-hydroxymuconate-6-semialdehyde decarboxylase from Paenibacillus sp. JJ-1b (see paper)
31% identity, 90% coverage of query (142 bits)
picC / A0A1X9WE52 3,6-dihydroxypicolinate decarboxylase from Alcaligenes faecalis (see paper)
30% identity, 75% coverage of query (97.1 bits)
Build an alignment for N515DRAFT_3778 and 17 homologs with ≥ 30% identity
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GRDC_POLSJ / Q12BV1 Gamma-resorcylate decarboxylase; Gamma-RSD; 2,6-dihydroxybenzoate decarboxylase; 2,6-DHBD; EC 4.1.1.103 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
Q12BV1 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Polaromonas sp. JS666 (see paper)
27% identity, 76% coverage of query (93.6 bits)
4qroA / Q12BV1 Crystal structure of dihydroxybenzoic acid decarbboxylase bpro_2061 (target efi-500288) from polaromonas sp. Js666 with bound manganese and an inhibitor, 2-nitroresorcinol
27% identity, 76% coverage of query (93.6 bits)
3nurA / A0A0H3K164 Crystal structure of a putative amidohydrolase from staphylococcus aureus
24% identity, 72% coverage of query (93.2 bits)
graF / Q60GU1 γ-resorcylate decarboxylase monomer (EC 4.1.1.103) from Rhizobium sp. (strain MTP-10005) (see 2 papers)
GRDC_RHIS5 / Q60GU1 Gamma-resorcylate decarboxylase; GRDC; Gamma-RDC; 2,6-dihydroxybenzoate decarboxylase; EC 4.1.1.103 from Rhizobium sp. (strain MTP-10005) (see 3 papers)
Q60GU1 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Rhizobium sp. (see 3 papers)
26% identity, 83% coverage of query (90.5 bits)
2dvtA / Q60GU1 Crystal structure of 2,6-dihydroxybenzoate decarboxylase from rhizobium
26% identity, 83% coverage of query (90.5 bits)
2dvxA Crystal structure of 2,6-dihydroxybenzoate decarboxylase complexed with inhibitor 2,3-dihydroxybenzaldehyde
26% identity, 83% coverage of query (90.5 bits)
2dvuA Crystal structure of 2,6-dihydroxybenzoate decarboxylase complexed with 2,6-dihydroxybenzoate
26% identity, 83% coverage of query (90.5 bits)
6m53B / N1S495 Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum (see paper)
25% identity, 83% coverage of query (90.1 bits)
X0JT48 o-pyrocatechuate decarboxylase (EC 4.1.1.46) from Fusarium odoratissimum NRRL 54006 (see paper)
25% identity, 83% coverage of query (90.1 bits)
4qrnA / Q2GA79 High-resolution crystal structure of 5-carboxyvanillate decarboxylase (target efi-505250) from novosphingobium aromaticivorans dsm 12444 complexed with manganese and 4-hydroxy-3-methoxy-5-nitrobenzoic acid
26% identity, 74% coverage of query (90.1 bits)
4infA Crystal structure of amidohydrolase saro_0799 (target efi-505250) from novosphingobium aromaticivorans dsm 12444 with bound calcium
26% identity, 74% coverage of query (90.1 bits)
7bp1A Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum in complex with catechol
25% identity, 83% coverage of query (90.1 bits)
tsdA / Q0SFL6 γ-resorcylate decarboxylase (EC 4.1.1.103) from Rhodococcus jostii (strain RHA1) (see 2 papers)
GRDC_RHOJR / Q0SFL6 Gamma-resorcylate decarboxylase; GRA decarboxylase; 2,6-dihydroxybenzoate decarboxylase; EC 4.1.1.103 from Rhodococcus jostii (strain RHA1) (see paper)
28% identity, 73% coverage of query (89.4 bits)
GRDC_RHIRD / Q60FX6 Gamma-resorcylate decarboxylase; 2,6-dihydroxybenzoate decarboxylase; Reversible gamma-RA decarboxylase; EC 4.1.1.103 from Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter) (see paper)
Q60FX6 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Agrobacterium tumefaciens (see paper)
26% identity, 83% coverage of query (89.4 bits)
7a19A / P80402 2,3-dihydroxybenzoate decarboxylase of aspergillus oryzae (see paper)
28% identity, 70% coverage of query (89.0 bits)
7bpcA Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum in complex with 2,5-dhba
25% identity, 82% coverage of query (89.0 bits)
7wjrA Crystal structure of dihydroxybenzoate decarboxylase mutant a63s from aspergillus oryzae in complex with catechol
28% identity, 70% coverage of query (88.6 bits)
8h41B / P0CT50 Crystal structure of a decarboxylase from trichosporon moniliiforme in complex with o-nitrophenol
23% identity, 85% coverage of query (75.9 bits)
3ij6A / Q5FK79 Crystal structure of an uncharacterized metal-dependent hydrolase from lactobacillus acidophilus
21% identity, 96% coverage of query (75.1 bits)
SDC_CUTMO / P0CT50 Salicylate decarboxylase; Salicylic acid decarboxylase; EC 4.1.1.91 from Cutaneotrichosporon moniliiforme (Yeast) (Trichosporon moniliiforme) (see paper)
P0CT50 salicylate decarboxylase (EC 4.1.1.91) from Cutaneotrichosporon moniliiforme (see paper)
23% identity, 82% coverage of query (74.3 bits)
6jqxA Crystal structure of a hydrogenase from trichosporon moniliiforme
23% identity, 82% coverage of query (74.3 bits)
6jqwA Crystal structure of a hydrogenase from trichosporon moniliiforme
23% identity, 82% coverage of query (74.3 bits)
ligY / Q9Z9I9 OH-DDVA meta-cleavage compound hydrolase from Sphingomonas paucimobilis (see paper)
24% identity, 77% coverage of query (70.5 bits)
5vn5C / G2IN02 Crystal structure of ligy from sphingobium sp. Strain syk-6 (see paper)
23% identity, 77% coverage of query (70.5 bits)
PATG_PENEN / A0A075TXZ1 6-methylsalicylic acid decarboxylase; Patulin biosynthesis cluster protein G; EC 4.1.1.52 from Penicillium expansum (Blue mold rot fungus) (see 8 papers)
25% identity, 76% coverage of query (70.1 bits)
6e6iA Crystal structure of 4-methyl hopda bound to ligy from sphingobium sp. Strain syk-6
23% identity, 77% coverage of query (70.1 bits)
ORSB_EMENI / Q5AUW9 Decarboxylase orsB; Orsellinic acid/F9775 biosynthesis cluster protein B; EC 4.1.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 4 papers)
orsB putative amidohydrolase from Emericella nidulans (see paper)
26% identity, 72% coverage of query (69.7 bits)
AR281_ARTOA / G1XU02 6-methylsalicylic acid decarboxylase; Sesquiterpenyl epoxy-cyclohexenoids cluster protein AOL_s00215g281; SECs cluster protein AOL_s00215g281; EC 4.1.1.52 from Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) (Nematode-trapping fungus) (Didymozoophaga oligospora) (see 3 papers)
G1XU02 6-methylsalicylate decarboxylase (EC 4.1.1.52) from Orbilia oligospora (see paper)
24% identity, 73% coverage of query (67.4 bits)
8sm7A / D3EI84 Air-oxidized g. Y4 truffo expressed from m9 minimal medium supplemented with fe (see paper)
26% identity, 71% coverage of query (52.0 bits)
6ompA / A0A0A0UVH9 Crystal structure of apo ptmu3 (see paper)
26% identity, 80% coverage of query (49.3 bits)
6omrB Crystal structure of ptmu3 complexed with ptn substrate
26% identity, 80% coverage of query (49.3 bits)
6omqB Crystal structure of ptmu3 complexed with ptm substrate
26% identity, 80% coverage of query (49.3 bits)
ACUB_ASPA1 / A0A1L9WN60 6-methylsalicylic acid decarboxylase acuB; Aculin biosynthesis cluster protein B; EC 4.1.1.52 from Aspergillus aculeatus (strain ATCC 16872 / CBS 172.66 / WB 5094) (see paper)
25% identity, 77% coverage of query (47.0 bits)
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Lawrence Berkeley National Laboratory