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Searching for up to 100 curated homologs for N515DRAFT_4292 FitnessBrowser__Dyella79:N515DRAFT_4292 (221 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Psest_3511 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas stutzeri RCH2
    56% identity, 98% coverage of query (242 bits)

SO1671 Maleylacetoacetate isomerase (EC 5.2.1.2) from Shewanella oneidensis MR-1
    56% identity, 96% coverage of query (240 bits)

2v6kA / O86043 Structure of maleyl pyruvate isomerase, a bacterial glutathione-s- transferase in zeta class, in complex with substrate analogue dicarboxyethyl glutathione (see paper)
    52% identity, 97% coverage of query (222 bits)

nagL / O86043 glutathion-dependent maleylpyruvate isomerase (EC 5.2.1.4) from Ralstonia sp. (see paper)
NAGL_RALSP / O86043 Maleylpyruvate isomerase; MPI; Naphthalene degradation protein L; EC 5.2.1.4 from Ralstonia sp. (see 2 papers)
    53% identity, 96% coverage of query (222 bits)

2jl4A Holo structure of maleyl pyruvate isomerase, a bacterial glutathione- s-transferase in zeta class
    53% identity, 96% coverage of query (222 bits)

Ac3H11_2306 Maleylacetoacetate isomerase (EC 5.2.1.2) from Acidovorax sp. GW101-3H11
    53% identity, 95% coverage of query (210 bits)

MAAI2_DROME / Q9VHD2 Probable maleylacetoacetate isomerase 2; MAAI 2; Glutathione S-transferase zeta 2; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    44% identity, 98% coverage of query (194 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    46% identity, 97% coverage of query (191 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    46% identity, 97% coverage of query (191 bits)

MAAI_RAT / P57113 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Rattus norvegicus (Rat) (see paper)
    45% identity, 97% coverage of query (187 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    44% identity, 97% coverage of query (186 bits)

Q5K5T6 glutathione transferase subunit (EC 2.5.1.18) from Escherichia coli (see 8 papers)
    45% identity, 96% coverage of query (181 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    43% identity, 97% coverage of query (181 bits)

MAAI1_DROME / Q9VHD3 Probable maleylacetoacetate isomerase 1; MAAI 1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    42% identity, 96% coverage of query (179 bits)

4kdyA / B8J605 Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound gsh in the active site
    50% identity, 98% coverage of query (179 bits)

4kaeA Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound dicarboxyethyl glutathione and citrate in the active site
    50% identity, 98% coverage of query (179 bits)

AO356_16835 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2C3
    45% identity, 96% coverage of query (168 bits)

Pf6N2E2_5292 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E2
    44% identity, 96% coverage of query (166 bits)

GSTZ1_ARATH / Q9ZVQ3 Glutathione S-transferase Z1; AtGSTZ1; GST class-zeta member 1; Glutathione S-transferase 18; Maleylacetone isomerase; MAI; EC 2.5.1.18; EC 5.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    43% identity, 97% coverage of query (166 bits)

AO353_15560 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E3
    43% identity, 96% coverage of query (164 bits)

4pxoA / C5ATQ9 Crystal structure of maleylacetoacetate isomerase from methylobacteriu extorquens am1 with bound malonate and gsh (target efi-507068)
    46% identity, 98% coverage of query (163 bits)

MAIA_ASPFU / Q4WHT7 Maleylacetoacetate isomerase maiA; EC 5.2.1.2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 3 papers)
    43% identity, 97% coverage of query (155 bits)

D2YW48 Probable glutathione S-transferase; EC 2.5.1.18 from Coccidioides immitis (strain RS) (Valley fever fungus)
    40% identity, 98% coverage of query (150 bits)

3n5oA / D2YW48 Crystal structure of putative glutathione transferase from coccidioides immitis bound to glutathione (see paper)
    40% identity, 98% coverage of query (149 bits)

O04437 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    37% identity, 99% coverage of query (142 bits)

maiA / O43123 maleylacetoacetate isomerase (EC 5.2.1.2) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (see paper)
MAAI_EMENI / O43123 Maleylacetoacetate isomerase; MAAI; EC 5.2.1.2 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
O43123 maleylacetoacetate isomerase (EC 5.2.1.2) from Aspergillus nidulans (see paper)
GI|2832725 maleylacetoacetate isomerase; EC 5.2.1.2 from Emericella nidulans (see paper)
maiA / CAA05041.1 maleylacetoacetate isomerase from Aspergillus nidulans (see paper)
maiA / CAA05044.1 maleylacetoacetate isomerase from Aspergillus nidulans (see paper)
    40% identity, 98% coverage of query (139 bits)

Build an alignment

Build an alignment for N515DRAFT_4292 and 26 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

GSTU5_ARATH / P46421 Glutathione S-transferase U5; AtGSTU5; AtGSTU1; GST class-tau member 5; Glutathione S-transferase 103-1A; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
P46421 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    29% identity, 95% coverage of query (68.6 bits)

8a0pA / D2X9R3 Crystal structure of poplar glutathione transferase u20 in complex with morin (see paper)
    32% identity, 77% coverage of query (67.8 bits)

8a0rA Crystal structure of poplar glutathione transferase u20 in complex with pinocembrin
    32% identity, 77% coverage of query (67.4 bits)

8a0qA Crystal structure of poplar glutathione transferase u20 in complex with baicalein
    32% identity, 77% coverage of query (67.4 bits)

8a0oA Crystal structure of poplar glutathione transferase u20 in complex with galangin
    32% identity, 77% coverage of query (67.4 bits)

8a0iA Crystal structure of poplar glutathione transferase u20 in complex with glutathionylphenylacetophenone
    32% identity, 77% coverage of query (67.4 bits)

8a08A Crystal structure of poplar glutathione transferase u20 in complex with glutathione
    32% identity, 77% coverage of query (67.4 bits)

7db3A Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in tdp011-bound form
    31% identity, 91% coverage of query (65.1 bits)

7dazA Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in tdp015- and gsh-bound form
    31% identity, 91% coverage of query (65.1 bits)

7daxA Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in tdp013-bound form
    31% identity, 91% coverage of query (65.1 bits)

7db0A Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in dimedone-bound form
    31% identity, 91% coverage of query (65.1 bits)

7db4A Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in tdp012- and glutathione-bound form
    31% identity, 91% coverage of query (65.1 bits)

6keoAA Glutathione S-transferase E14
    31% identity, 91% coverage of query (65.1 bits)

GSTEE_DROME / Q7JYX0 Glutathione S-transferase E14; Protein noppera-bo; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see 3 papers)
    31% identity, 91% coverage of query (64.3 bits)

A0A4Y5R032 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    32% identity, 74% coverage of query (64.3 bits)

4ielB / Q0B681 Crystal structure of a glutathione s-transferase family protein from burkholderia ambifaria, target efi-507141, with bound glutathione
    33% identity, 76% coverage of query (64.3 bits)

6t2tA / Q7JYX0 Crystal structure of drosophila melanogaster glutathione s-transferase epsilon 14 in complex with glutathione and 2-methyl-2,4-pentanediol (see paper)
    31% identity, 91% coverage of query (64.3 bits)

7dw4A / A0A4Y5R032 Crystal structure of a glutathione s-transferase mutant sbgstu6(i55t) from salix babylonica in complex with glutathione
    32% identity, 74% coverage of query (62.8 bits)

7zvpA Crystal structure of poplar glutathione transferase u19 in complex with glutathione
    30% identity, 77% coverage of query (62.8 bits)

GSTF3_MAIZE / P04907 Glutathione S-transferase 3; GST class-phi member 3; GST-III; EC 2.5.1.18 from Zea mays (Maize) (see 2 papers)
    32% identity, 93% coverage of query (62.4 bits)

A0A4Y5R087 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 76% coverage of query (62.0 bits)

7dweA / A0A4Y5R087 Crystal structure of a glutathione s-transferase sbgstu7 from salix babylonica in complex with glutathione
    29% identity, 76% coverage of query (62.0 bits)

Q6DNI8 glutathione transferase (EC 2.5.1.18) from Pinus tabuliformis (see paper)
    25% identity, 95% coverage of query (61.6 bits)

A0A4Y5QZX2 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    27% identity, 85% coverage of query (61.6 bits)

Q9FQE8 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    29% identity, 79% coverage of query (61.2 bits)

7zznA Crystal structure of poplar glutathione transferase u20
    31% identity, 77% coverage of query (61.2 bits)

GSTU1_ARATH / Q9ZW30 Glutathione S-transferase U1; AtGSTU1; GST class-tau member 1; Glutathione S-transferase 19; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    27% identity, 93% coverage of query (60.5 bits)

gst3b / CAB38119.1 Glutathione transferase III(b) from Zea mays (see paper)
    31% identity, 93% coverage of query (59.7 bits)

7y55A / A0A9E8RZN7 Crystal structure of a glutathione s-transferase tau1 from pinus densata in complex with gsh
    25% identity, 91% coverage of query (59.3 bits)

A0A4Y5QZW9 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    30% identity, 78% coverage of query (58.9 bits)

A0A4Y5QZZ8 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    27% identity, 76% coverage of query (58.9 bits)

A0A4Y5QZX0 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 78% coverage of query (58.5 bits)

gst3a / CAB38118.1 Glutathione transferase III(a) from Zea mays (see paper)
    33% identity, 76% coverage of query (58.5 bits)

4chsA Crystal structure of a tau class glutathione transferase 10 from glycine max
    28% identity, 79% coverage of query (58.5 bits)

Q8RW03 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    31% identity, 77% coverage of query (57.8 bits)

O49235 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    26% identity, 100% coverage of query (57.8 bits)

5agyA / I1MJ34 Crystal structure of a tau class gst mutant from glycine (see paper)
    26% identity, 100% coverage of query (57.4 bits)

A0A4Y5R0C1 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    28% identity, 77% coverage of query (57.4 bits)

Q9ZW27 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    26% identity, 95% coverage of query (57.0 bits)

Q9ZW28 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    26% identity, 94% coverage of query (56.6 bits)

B3VQJ6 glutathione transferase (EC 2.5.1.18) from Phanerodontia chrysosporium (see paper)
    26% identity, 78% coverage of query (56.6 bits)

GSTFA_ARATH / P42761 Glutathione S-transferase F10; AtGSTF10; AtGSTF4; GST class-phi member 10; Protein EARLY RESPONSE TO DEHYDRATION 13; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    30% identity, 73% coverage of query (55.8 bits)

3pr8A / Q88RE7 Structure of glutathione s-transferase(pp0183) from pseudomonas putida in complex with gsh
    29% identity, 82% coverage of query (55.5 bits)

Pog / b3229 stringent starvation protein A from Escherichia coli K-12 substr. MG1655 (see 8 papers)
TC 1.A.12.3.1 / P0ACA3 The bacterial CLIC homologue, stringent starvation protein A, SspA (212 aas; 0 TMSs) [N-terminal Trx domain; C-terminal glutathione S-transferase (GST) domain] from Escherichia coli (strain K12) (see 5 papers)
sspA stringent starvation protein A from Escherichia coli K12 (see 5 papers)
    30% identity, 77% coverage of query (55.5 bits)

6ezyB / O80852 Arabidopsis thaliana gstf9, gsh and gsoh bound (see paper)
    30% identity, 71% coverage of query (55.5 bits)

6f01B Arabidopsis thaliana gstf9, gso3 and gsoh bound
    30% identity, 71% coverage of query (55.5 bits)

4topA Glycine max glutathione transferase
    26% identity, 99% coverage of query (55.5 bits)

GSTF9_ARATH / O80852 Glutathione S-transferase F9; AtGSTF9; AtGSTF7; GST class-phi member 9; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    30% identity, 71% coverage of query (55.1 bits)

D2WL48 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    28% identity, 79% coverage of query (55.1 bits)

8awzA / A0A384E145 Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with dinitrosyl glutathionyl iron complex (dngic) (see paper)
    27% identity, 93% coverage of query (54.3 bits)

A0A384E145 glutathione transferase (EC 2.5.1.18) from Trametes versicolor (see paper)
    27% identity, 93% coverage of query (54.3 bits)

8ax0A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with sodium nitroprusside
    27% identity, 93% coverage of query (54.3 bits)

6hpeA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with the glutathione adduct of phenethyl- isothiocyanate
    27% identity, 93% coverage of query (54.3 bits)

6f6aA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with dihydrowogonin from wild-cherry extract
    27% identity, 93% coverage of query (54.3 bits)

6f69A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 2,3,4-trihydroxybenzophenone
    27% identity, 93% coverage of query (54.3 bits)

6f68A Crystal structure glutathione transferase omega 3s from trametes versicolor in complex with 2,4,4'-trihydroxybenzophenone
    27% identity, 93% coverage of query (54.3 bits)

6f67A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 3,4-dihydroxybenzophenone
    27% identity, 93% coverage of query (54.3 bits)

6f66A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 2,4-dihydroxybenzophenone
    27% identity, 93% coverage of query (54.3 bits)

6f4kA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with hexyl-glutathione
    27% identity, 93% coverage of query (54.3 bits)

6f4fA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-s-dinitrobenzene
    27% identity, 93% coverage of query (54.3 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    25% identity, 82% coverage of query (53.1 bits)

8ax1A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with hydroxy-tetranitro-nitrosyl-ruthenate
    27% identity, 91% coverage of query (52.8 bits)

6f51A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-phenylacetophenone
    27% identity, 91% coverage of query (52.8 bits)

4mf6A / B1FXZ2 Crystal structure of glutathione transferase bgramdraft_1843 from burkholderia graminis, target efi-507289, with two glutathione molecules bound per one protein subunit
    28% identity, 87% coverage of query (52.0 bits)

4nhwD Crystal structure of glutathione transferase smc00097 from sinorhizobium meliloti, target efi-507275, with one glutathione bound per one protein subunit
    28% identity, 95% coverage of query (51.2 bits)

3vlnA Human glutathione transferase o1-1 c32s mutant in complex with ascorbic acid
    22% identity, 95% coverage of query (49.7 bits)

4kdxA / B1FZ96 Crystal structure of a glutathione transferase family member from burkholderia graminis, target efi-507264, bound gsh, ordered domains, space group p21, form(1)
    27% identity, 76% coverage of query (49.7 bits)

6mhdA Glutathione s-transferase omega 1 bound to covalent inhibitor 44
    22% identity, 91% coverage of query (48.9 bits)

6mhcA / P78417 Glutathione s-transferase omega 1 bound to covalent inhibitor 37 (see paper)
    22% identity, 91% coverage of query (48.9 bits)

4yqvA Glutathione s-transferase omega 1 bound to covalent inhibitor c4-10
    22% identity, 91% coverage of query (48.5 bits)

4yqmA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-27
    22% identity, 91% coverage of query (48.5 bits)

1eemA Glutathione transferase from homo sapiens
    22% identity, 91% coverage of query (48.5 bits)

6pnoA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n- isopropylsulfamoyl)phenyl)acetamide
    22% identity, 91% coverage of query (48.5 bits)

6pnmA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3- (morpholinosulfonyl)phenyl)acetamide
    22% identity, 91% coverage of query (48.5 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory