Searching for up to 100 curated homologs for PP_0114 FitnessBrowser__Putida:PP_0114 (335 a.a.)
Found high-coverage hits (≥70%) to 63 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.24.5 / Q9HT70 Methionine import ATP-binding protein MetN 2, component of L-Histidine uptake porter, MetIQN from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
82% identity, 100% coverage of query (566 bits)
METN_BACSU / O32169 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.24.2 / O32169 MetN (C) (aka YusC), component of The L- and D-methionine porter (also transports methionine sulfoxide from Bacillus subtilis subsp. subtilis str. 168 (see 2 papers)
52% identity, 95% coverage of query (324 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
49% identity, 100% coverage of query (318 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
48% identity, 100% coverage of query (317 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
48% identity, 100% coverage of query (317 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
48% identity, 100% coverage of query (317 bits)
TC 3.A.1.24.3 / Q8K8K8 AtmD (MetN), component of The methionine porter, AtmBDE from Streptococcus pyogenes serotype M3 (see 2 papers)
44% identity, 100% coverage of query (283 bits)
TC 3.A.1.24.4 / Q8NSN2 Methionine import ATP-binding protein metN, component of L-Methionine uptake porter, MetQNI from Corynebacterium glutamicum (see paper)
45% identity, 93% coverage of query (269 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
45% identity, 73% coverage of query (199 bits)
ARTM_BACSU / P54537 Arginine transport ATP-binding protein ArtM from Bacillus subtilis (strain 168) (see paper)
42% identity, 73% coverage of query (192 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
41% identity, 71% coverage of query (191 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
43% identity, 73% coverage of query (191 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
43% identity, 73% coverage of query (191 bits)
2olkA Abc protein artp in complex with adp-beta-s
43% identity, 73% coverage of query (191 bits)
2oljA Abc protein artp in complex with adp/mg2+
43% identity, 73% coverage of query (191 bits)
SMc02121 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, ATPase component from Sinorhizobium meliloti 1021
43% identity, 73% coverage of query (189 bits)
TC 3.A.1.3.25 / Q9CES4 Glutamine ABC transporter ATP-binding protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
42% identity, 73% coverage of query (187 bits)
TCYN_BACSU / O34900 L-cystine import ATP-binding protein TcyN; EC 7.4.2.- from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.3.13 / O34900 TcyN (YtmN), component of Uptake system for L-cystine (Km=2.5 μM), L-cystathionine, L-djenkolate ( 2-amino-3-[(2-amino-3-hydroxy-3-oxopropyl)sulfanylmethylsulfanyl] propanoic acid), and S-methyl-L-cysteine from Bacillus subtilis (see 4 papers)
41% identity, 73% coverage of query (185 bits)
GLUA_CORGL / P48243 Glutamate transport ATP-binding protein GluA; Glutamate uptake system protein GluA; EC 7.4.2.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 3.A.1.3.9 / P48243 GluA aka CGL1950, component of Glutamate porter from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
45% identity, 72% coverage of query (185 bits)
YXEO_BACSU / P54954 Probable amino-acid import ATP-binding protein YxeO; EC 7.4.2.- from Bacillus subtilis (strain 168) (see paper)
41% identity, 70% coverage of query (185 bits)
YhdZ / b3271 putative ABC transporter ATP-binding subunit YhdZ from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yhdZ / RF|NP_417737 uncharacterized amino-acid ABC transporter ATP-binding protein yhdZ from Escherichia coli K12 (see 3 papers)
41% identity, 73% coverage of query (182 bits)
TC 3.A.1.3.7 / Q52666 BztD, component of Glutamate/glutamine/aspartate/asparagine porter from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see paper)
41% identity, 73% coverage of query (181 bits)
Pf6N2E2_5405 ABC transporter for D-Alanine, ATPase component from Pseudomonas fluorescens FW300-N2E2
41% identity, 73% coverage of query (180 bits)
HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
43% identity, 71% coverage of query (165 bits)
1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
43% identity, 71% coverage of query (164 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
36% identity, 72% coverage of query (149 bits)
5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
39% identity, 72% coverage of query (148 bits)
5lilA / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atpys (p21) (see paper)
36% identity, 71% coverage of query (145 bits)
5lj7A / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atp (p21) (see paper)
36% identity, 71% coverage of query (145 bits)
1g291 / Q9YGA6 Malk (see paper)
36% identity, 73% coverage of query (141 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
33% identity, 72% coverage of query (135 bits)
4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
38% identity, 74% coverage of query (135 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
36% identity, 72% coverage of query (124 bits)
sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
31% identity, 90% coverage of query (124 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
31% identity, 70% coverage of query (122 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
31% identity, 70% coverage of query (122 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
31% identity, 70% coverage of query (122 bits)
AB25B_ARATH / Q9LVM1 ABC transporter B family member 25, mitochondrial; ABC transporter ABCB.25; AtABCB25; ABC transporter of the mitochondrion 3; AtATM3; Iron-sulfur clusters transporter ATM3; Protein STARIK 1 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.210.8 / Q9LVM1 Mitochondrial ABC transporter, ATM3, involved in iron homeostasis (Chen et al. 2007) and heavy metal resistance (Kim et al. 2006). There are three isoforms: ATM1, ATM2 and ATM3 (Chen et al., 2007). ATM3 can replace the yeast iron/sulfur cluster exporter better than ATM1 or ATM2. Atm3 is most similar to the human and yeast homologues, TC# 3.A.1.210.4 and 3.A.1.210.1, 51% and 47% identical, respectively from Arabidopsis thaliana (Mouse-ear cress) (see 11 papers)
GB|AAN13224.1 putative ABC transporter protein from Arabidopsis thaliana (see paper)
33% identity, 74% coverage of query (118 bits)
4fwiB / Q8RDH4 Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
33% identity, 73% coverage of query (116 bits)
TGD3_ARATH / Q9AT00 Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic; ABC transporter I family member 13; ABC transporter ABCI.13; AtABCI13; Non-intrinsic ABC protein 11; AtNAP11 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.27.2 / Q9AT00 Tdg3, component of The chloroplast lipid (trigalactosyl diacyl glycerol (TDG)) transporter, Tdg1,2,3 (Lu et al., 2007). Lipids such as mono- and digalactolipids are synthesized in the endoplasmic reticulum (ER) of plant cells and transferred to the thylakoid membranes of chloroplasts. Mutations in an outer chloroplastic envelope protein with 350 aas and 7 putative TMSs in the last 250 residues may catalyze translocation as part of a lipid transfer complex from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
31% identity, 72% coverage of query (116 bits)
DPPD_CALS4 / Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
33% identity, 73% coverage of query (116 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
31% identity, 72% coverage of query (113 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
31% identity, 72% coverage of query (112 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
31% identity, 72% coverage of query (112 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
31% identity, 72% coverage of query (112 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
31% identity, 72% coverage of query (112 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
31% identity, 72% coverage of query (112 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
31% identity, 72% coverage of query (112 bits)
Build an alignment for PP_0114 and 48 homologs with ≥ 30% identity
Or download the sequences
SapD / b1291 putrescine ABC exporter ATP binding protein SapD (EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
SapD / P0AAH4 putrescine ABC exporter ATP binding protein SapD (EC 7.6.2.16) from Escherichia coli (strain K12) (see 5 papers)
SAPD_ECOLI / P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see 2 papers)
27% identity, 73% coverage of query (112 bits)
4f4cA / P34712 The crystal structure of the multi-drug transporter (see paper)
33% identity, 75% coverage of query (107 bits)
8jwiA Cryo-em structure of the outward-facing plasmodium falciparum multidrug resistance protein 1
28% identity, 73% coverage of query (107 bits)
7pslA / P40416 S. Cerevisiae atm1 in msp1d1 nanodiscs in nucleotide-free state (see paper)
31% identity, 76% coverage of query (103 bits)
4myhB Structure of the glutathione bound mitochondrial abc transporter, atm1
31% identity, 76% coverage of query (103 bits)
ATM1_YEAST / P40416 Iron-sulfur clusters transporter ATM1, mitochondrial; EC 7.-.-.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
TC 3.A.1.210.1 / P40416 The mitochondrial iron transporter, ATM1 from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
ATM1 / RF|NP_014030.1 iron-sulfur clusters transporter ATM1, mitochondrial from Saccharomyces cerevisiae
31% identity, 76% coverage of query (102 bits)
7psnA S. Cerevisiae atm1 in msp1e3d1 nanodiscs with bound amp-pnp and mg2+
31% identity, 73% coverage of query (101 bits)
7psmA S. Cerevisiae atm1 in msp1d1 nanodiscs with bound amp-pnp and mg2+
31% identity, 73% coverage of query (101 bits)
8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
30% identity, 73% coverage of query (100 bits)
5d3mB Folate ecf transporter: amppnp bound state
30% identity, 73% coverage of query (100 bits)
MDL1_YEAST / P33310 ATP-dependent permease MDL1, mitochondrial; ABC transporter MDL1; Multidrug resistance-like protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
TC 3.A.1.212.1 / P33310 The mitochondrial peptide exporter, Mdl1p (exports peptides of 6-21 amino acyl residues from the mitochondrial matrix as well as degradation products of misassembled respiratory chain complexes) (Janas et al., 2003; van der Does et al., 2006; Gompf et al., 2007). A leaderless Mdl1p targets to the ER membrane instead of to the mitochondria from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
MDL1 / RF|NP_013289.1 ATP-dependent permease MDL1, mitochondrial; EC 3.6.3.43 from Saccharomyces cerevisiae (see paper)
29% identity, 75% coverage of query (100 bits)
8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
30% identity, 73% coverage of query (99.4 bits)
ABCB7_HUMAN / O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ABC transporter 7 protein from Homo sapiens (Human) (see 8 papers)
TC 3.A.1.210.4 / O75027 ABC7 or ABCB7 iron transporter (X-linked sideroblastis anemia protein, XLSA/A (Fujiwara and Harigae 2013)) from Homo sapiens (Human) (see 9 papers)
29% identity, 76% coverage of query (97.8 bits)
ABCA3_MOUSE / Q8R420 Phospholipid-transporting ATPase ABCA3; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Mus musculus (Mouse) (see 7 papers)
27% identity, 79% coverage of query (97.4 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
27% identity, 84% coverage of query (86.3 bits)
Or start over
Lawrence Berkeley National Laboratory