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Searching for up to 100 curated homologs for PP_0372 PP_0372 Acetylornithine aminotransferase 2 (426 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

2ordA / Q9X2A5 Crystal structure of acetylornithine aminotransferase (ec 2.6.1.11) (acoat) (tm1785) from thermotoga maritima at 1.40 a resolution
    41% identity, 86% coverage of query (281 bits)

Q9X2A5 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
    41% identity, 86% coverage of query (281 bits)

aruC / O30508 succinylornithine transaminase subunit (EC 2.6.1.13; EC 2.6.1.11; EC 2.6.1.81) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
ARUC_PSEAE / O30508 Succinylornithine transaminase/acetylornithine aminotransferase; ACOAT; SOAT; Succinylornithine aminotransferase; EC 2.6.1.11; EC 2.6.1.81 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
O30508 succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas aeruginosa (see paper)
    40% identity, 92% coverage of query (257 bits)

2eh6A / O66442 Crystal structure of acetylornithine aminotransferase from aquifex aeolicus vf5
    39% identity, 86% coverage of query (250 bits)

O66442 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Aquifex aeolicus (strain VF5)
    39% identity, 86% coverage of query (250 bits)

slr1022 / P73133 bifunctional acetylornithine transaminase/4-aminobutyrate—2-oxoglutarate transaminase (EC 2.6.1.19; EC 2.6.1.11) from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 4 papers)
P73133 acetylornithine transaminase (EC 2.6.1.11); 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Synechococcus sp. PCC 6803 (see paper)
    40% identity, 86% coverage of query (246 bits)

A8J933 acetylornithine transaminase (EC 2.6.1.11) from Chlamydomonas reinhardtii (see paper)
    38% identity, 88% coverage of query (243 bits)

PS417_21710 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas simiae WCS417
    40% identity, 91% coverage of query (239 bits)

B1XNF8 acetylornithine transaminase (EC 2.6.1.11); 4-aminobutyrate-2-oxoglutarate transaminase (EC 2.6.1.19) from Synechococcus sp. PCC 7002 (see paper)
    36% identity, 90% coverage of query (239 bits)

BWI76_RS11670 Succinylornithine transaminase (EC 2.6.1.81) from Klebsiella michiganensis M5al
    39% identity, 90% coverage of query (238 bits)

Dtu / b3359 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase (EC 2.6.1.11; EC 2.6.1.17) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
argD / P18335 N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase (EC 2.6.1.11; EC 2.6.1.17) from Escherichia coli (strain K12) (see 12 papers)
ARGD_ECOLI / P18335 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Escherichia coli (strain K12) (see paper)
    38% identity, 90% coverage of query (237 bits)

HP15_3042 acetylornithine aminotransferase (EC 2.6.1.11); succinylornithine aminotransferase (EC 2.6.1.81) from Marinobacter adhaerens HP15
    38% identity, 92% coverage of query (237 bits)

AZOBR_RS19025 acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] from Azospirillum brasilense Sp245
    41% identity, 89% coverage of query (234 bits)

Pf1N1B4_3440 Succinylornithine transaminase (EC 2.6.1.81) from Pseudomonas fluorescens FW300-N1B4
    40% identity, 89% coverage of query (234 bits)

A0A140N9B6 succinylornithine transaminase (EC 2.6.1.81) from Escherichia coli (see paper)
    38% identity, 91% coverage of query (229 bits)

4adbB / P77581 Structural and functional study of succinyl-ornithine transaminase from e. Coli (see paper)
    38% identity, 91% coverage of query (228 bits)

AstC / b1748 succinylornithine transaminase (EC 2.6.1.81; EC 2.6.1.11) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
astC / P77581 succinylornithine transaminase (EC 2.6.1.81; EC 2.6.1.11) from Escherichia coli (strain K12) (see 6 papers)
ASTC_ECOLI / P77581 Succinylornithine transaminase; SOAT; Carbon starvation protein C; Succinylornithine aminotransferase; EC 2.6.1.81 from Escherichia coli (strain K12) (see paper)
astC / RF|NP_416262.1 succinylornithine transaminase; EC 2.6.1.81 from Escherichia coli K12 (see 5 papers)
    38% identity, 91% coverage of query (228 bits)

4addA Structural and functional study of succinyl-ornithine transaminase from e. Coli
    38% identity, 91% coverage of query (228 bits)

ASTC_SALTY / Q8ZPV2 Succinylornithine transaminase; SOAT; Succinylornithine aminotransferase; EC 2.6.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    39% identity, 91% coverage of query (227 bits)

4jevB / P40732 N-acetylornithine aminotransferase from s. Typhimurium complexed with gabaculine
    37% identity, 90% coverage of query (226 bits)

ARGD_SALTY / P40732 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    37% identity, 90% coverage of query (225 bits)

4jewA N-acetylornithine aminotransferase from s. Typhimurium complexed with l-canaline
    37% identity, 90% coverage of query (225 bits)

2pb0A Structure of biosynthetic n-acetylornithine aminotransferase from salmonella typhimurium: studies on substrate specificity and inhibitor binding
    37% identity, 90% coverage of query (225 bits)

8ht4B / Q59282 Crystal structure of acetylornithine aminotransferase complex with plp from corynebacterium glutamicum
    36% identity, 86% coverage of query (219 bits)

ARGD_ARATH / Q9M8M7 Acetylornithine aminotransferase, chloroplastic/mitochondrial; ACOAT; Acetylornithine transaminase; AOTA; Protein HOPW1-1-INTERACTING 1; EC 2.6.1.11 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    37% identity, 86% coverage of query (213 bits)

OAT_PLAF7 / Q6LFH8 Ornithine aminotransferase; PfOAT; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Plasmodium falciparum (isolate 3D7) (see 2 papers)
Q6LFH8 ornithine aminotransferase (EC 2.6.1.13) from Plasmodium falciparum (see 2 papers)
    35% identity, 86% coverage of query (205 bits)

OAT_EMENI / Q92413 Ornithine aminotransferase; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
otaA ornithine aminotransferase; EC 2.6.1.13 from Emericella nidulans (see paper)
    35% identity, 87% coverage of query (200 bits)

A0A3B6KM96 ornithine aminotransferase (EC 2.6.1.13) from Triticum aestivum (see paper)
    34% identity, 89% coverage of query (198 bits)

δOAT / Q1RPP3 ornithine δ-aminotransferase (EC 2.6.1.13) from Pinus sylvestris (see paper)
dOAT / CAJ76070.1 ornithine aminotransferase from Pinus sylvestris (see paper)
    36% identity, 84% coverage of query (196 bits)

A0A3B6LSQ4 ornithine aminotransferase (EC 2.6.1.13) from Triticum aestivum (see paper)
    34% identity, 89% coverage of query (195 bits)

δ-OAT / Q9FNK4 ornithine-δ-aminotransferase (EC 2.6.1.13) from Arabidopsis thaliana (see 2 papers)
OAT_ARATH / Q9FNK4 Ornithine aminotransferase, mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9FNK4 ornithine aminotransferase (EC 2.6.1.13) from Arabidopsis thaliana (see paper)
    35% identity, 84% coverage of query (195 bits)

A0A3B6MXE9 ornithine aminotransferase (EC 2.6.1.13) from Triticum aestivum (see paper)
    34% identity, 89% coverage of query (194 bits)

OAT / P04181 Ornithine aminotransferase (EC 2.6.1.13) from Homo sapiens (see 3 papers)
OAT_HUMAN / P04181 Ornithine aminotransferase, mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Homo sapiens (Human) (see 8 papers)
    37% identity, 84% coverage of query (194 bits)

OAT_ORYSJ / Q10G56 Ornithine aminotransferase, mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Oryza sativa subsp. japonica (Rice) (see paper)
    35% identity, 86% coverage of query (194 bits)

7lomC Ornithine aminotransferase (oat) soaked with its inactivator - (1s, 3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
    38% identity, 84% coverage of query (194 bits)

7lomA Ornithine aminotransferase (oat) soaked with its inactivator - (1s, 3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
    38% identity, 84% coverage of query (194 bits)

7lonA Ornithine aminotransferase (oat) cocrystallized with its inactivator - (1s,3s)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid
    38% identity, 84% coverage of query (194 bits)

7ta0A Human ornithine aminotransferase (hoat) soaked with 5-aminovaleric acid
    37% identity, 84% coverage of query (194 bits)

8ez1B Human ornithine aminotransferase (hoat) co-crystallized with its inactivator 3-amino-4-fluorocyclopentenecarboxylic acid
    37% identity, 84% coverage of query (194 bits)

8ez1A Human ornithine aminotransferase (hoat) co-crystallized with its inactivator 3-amino-4-fluorocyclopentenecarboxylic acid
    37% identity, 84% coverage of query (194 bits)

7tfpC Human ornithine aminotransferase cocrystallized with its inhibitor, (1s,3s)-3-amino-4-(difluoromethylene)cyclopentane-1-carboxylic acid.
    37% identity, 84% coverage of query (194 bits)

7lk0A Ornithine aminotransferase (oat) cocrystallized with its potent inhibitor - (s)-3-amino-4,4-difluorocyclopent-1-enecarboxylic acid (ss-1-148)
    37% identity, 84% coverage of query (194 bits)

7jx9A The crystal structure of human ornithine aminotransferase with an intermediate bound during inactivation by (1s,3s)-3-amino-4- (hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic acid.
    37% identity, 84% coverage of query (194 bits)

6v8dA Design, synthesis, and mechanism of fluorine-substituted cyclohexene analogues of gama-aminobutyric acid (gaba) as selective ornithine aminotransferase inactivators
    37% identity, 84% coverage of query (194 bits)

2canA Human ornithine aminotransferase complexed with l-canaline
    37% identity, 84% coverage of query (194 bits)

1gbnB Human ornithine aminotransferase complexed with the neurotoxin gabaculine
    37% identity, 84% coverage of query (194 bits)

1gbnA Human ornithine aminotransferase complexed with the neurotoxin gabaculine
    37% identity, 84% coverage of query (194 bits)

7tedA Human ornithine aminotransferase cocrystallized with its inhibitor, (s,e)-3-amino-4-(fluoromethylene)cyclopent-1-ene-1-carboxylate
    37% identity, 84% coverage of query (194 bits)

7ta1A Human ornithine aminotransferase (hoat) soaked with gamma-aminobutyric acid
    37% identity, 84% coverage of query (194 bits)

7lnmB Ornithine aminotransferase (oat) cocrystallized with its inactivator - (1s,3s)-3-amino-4-(difluoromethylene)cyclopentene-1-carboxylic acid
    37% identity, 84% coverage of query (194 bits)

7lk1A Ornithine aminotransferase (oat) with its potent inhibitor - (s)-3- amino-4,4-difluorocyclopent-1-enecarboxylic acid (ss-1-148) - 1 hour soaking
    37% identity, 84% coverage of query (194 bits)

6v8cA Design, synthesis, and mechanism of fluorine-substituted cyclohexene analogues of gama-aminobutyric acid (gaba) as selective ornithine aminotransferase inactivators
    37% identity, 84% coverage of query (194 bits)

6oiaA (1s,3s)-3-amino-4-(perfluoropropan-2-ylidene)cyclopentane-1-carboxylic acid hydrochloride, a potent inhibitor of ornithine aminotransferase
    37% identity, 84% coverage of query (194 bits)

5vwoA Ornithine aminotransferase inactivated by (1r,3s,4s)-3-amino-4- fluorocyclopentane-1-carboxylic acid (fcp)
    37% identity, 84% coverage of query (194 bits)

2oatA Ornithine aminotransferase complexed with 5-fluoromethylornithine
    37% identity, 84% coverage of query (194 bits)

2byjA / P04181 Ornithine aminotransferase mutant y85i (see paper)
    37% identity, 84% coverage of query (193 bits)

CH_124176 ornithine aminotransferase from Magnaporthe grisea 70-15 (see paper)
    32% identity, 88% coverage of query (193 bits)

A0QYS9 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
    37% identity, 85% coverage of query (193 bits)

argD / CAB82482.1 acetylornithine aminotransferase from Streptomyces clavuligerus (see 3 papers)
    38% identity, 88% coverage of query (192 bits)

Q98TS5 ornithine aminotransferase (EC 2.6.1.13) from Xenopus laevis (see paper)
    36% identity, 83% coverage of query (192 bits)

B1A0U3 ornithine aminotransferase (EC 2.6.1.13) from Pisum sativum (see 2 papers)
    35% identity, 84% coverage of query (192 bits)

A0A674DA32 ornithine aminotransferase (EC 2.6.1.13) from Salmo trutta (see paper)
    36% identity, 83% coverage of query (190 bits)

OAT_RAT / P04182 Ornithine aminotransferase, mitochondrial; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Rattus norvegicus (Rat) (see paper)
    36% identity, 83% coverage of query (190 bits)

Q5SHH5 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
    36% identity, 85% coverage of query (188 bits)

lysJ / Q93R93 L-2-aminoadipate semialdehyde transaminase monomer (EC 2.6.1.118) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
LYSJ_THET2 / Q93R93 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
Q93R93 [amino group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase (EC 2.6.1.118) from Thermus thermophilus (see 2 papers)
    35% identity, 85% coverage of query (187 bits)

1vefA / Q5SHH5 Acetylornithine aminotransferase from thermus thermophilus hb8
    35% identity, 85% coverage of query (187 bits)

1wkhA Acetylornithine aminotransferase from thermus thermophilus hb8
    35% identity, 85% coverage of query (187 bits)

1wkgA Acetylornithine aminotransferase from thermus thermophilus hb8
    35% identity, 85% coverage of query (187 bits)

Q3ZCF5 ornithine aminotransferase (EC 2.6.1.13) from Bos taurus (see paper)
    36% identity, 83% coverage of query (186 bits)

Echvi_0577 Ornithine aminotransferase (EC 2.6.1.13) from Echinicola vietnamensis KMM 6221, DSM 17526
    34% identity, 83% coverage of query (185 bits)

OAT_BACSU / P38021 Ornithine aminotransferase; OAT; Ornithine--oxo-acid aminotransferase; EC 2.6.1.13 from Bacillus subtilis (strain 168) (see 2 papers)
    33% identity, 84% coverage of query (184 bits)

3nx3A / Q9PIR7 Crystal structure of acetylornithine aminotransferase (argd) from campylobacter jejuni
    31% identity, 88% coverage of query (181 bits)

P9WPZ7 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    36% identity, 84% coverage of query (181 bits)

7nn4A / P9WPZ7 Crystal structure of mycobacterium tuberculosis argd with prosthetic group pyridoxal 5'-phosphate and 3-hydroxy-2-naphthoic acid.
    36% identity, 84% coverage of query (180 bits)

arg1 / RF|NP_588255.1 acetylornithine aminotransferase; EC 2.6.1.11 from Schizosaccharomyces pombe (see paper)
    33% identity, 86% coverage of query (180 bits)

7nncC Crystal structure of mycobacterium tuberculosis argd with prosthetic group pyridoxal-5'-phosphate and 6-methoxyquinoline-3-carboxylic acid
    36% identity, 84% coverage of query (180 bits)

A0A5F9CII4 ornithine aminotransferase (EC 2.6.1.13) from Oryctolagus cuniculus (see paper)
    34% identity, 83% coverage of query (177 bits)

BT3758 N-succinylornithine aminotransferase (EC 2.6.1.81) from Bacteroides thetaiotaomicron VPI-5482
    34% identity, 85% coverage of query (177 bits)

ARG8 / P18544 acetylornithine transaminase (EC 2.6.1.11) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 9 papers)
ARGD_YEAST / P18544 Acetylornithine aminotransferase, mitochondrial; ACOAT; EC 2.6.1.11 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    31% identity, 87% coverage of query (175 bits)

4uoxC / P42588 Crystal structure of ygjg in complex with pyridoxal-5'-phosphate and putrescine (see paper)
    35% identity, 85% coverage of query (174 bits)

PatA / b3073 putrescine aminotransferase (EC 2.6.1.29) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
patA / P42588 putrescine aminotransferase (EC 2.6.1.82; EC 2.6.1.29) from Escherichia coli (strain K12) (see 15 papers)
PAT_ECOLI / P42588 Putrescine aminotransferase; PAT; PATase; Cadaverine transaminase; Diamine transaminase; Putrescine transaminase; Putrescine--2-oxoglutaric acid transaminase; Putrescine:2-OG aminotransferase; EC 2.6.1.82; EC 2.6.1.29 from Escherichia coli (strain K12) (see 8 papers)
P42588 putrescine-2-oxoglutarate transaminase (EC 2.6.1.82) from Escherichia coli (see 4 papers)
    35% identity, 85% coverage of query (174 bits)

Q2Z0F8 ornithine aminotransferase (EC 2.6.1.13) from Agaricus bisporus (see paper)
    31% identity, 88% coverage of query (174 bits)

4uoxA Crystal structure of ygjg in complex with pyridoxal-5'-phosphate and putrescine
    35% identity, 85% coverage of query (174 bits)

5eqcA / S8EY38 Structure of the ornithine aminotransferase from toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of plp at the protein active site
    32% identity, 88% coverage of query (173 bits)

5e3kB Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with (s)-4-amino-5-fluoropentanoic acid
    32% identity, 88% coverage of query (173 bits)

5e3kA Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with (s)-4-amino-5-fluoropentanoic acid
    32% identity, 86% coverage of query (172 bits)

5e5iA Structure of the ornithine aminotransferase from toxoplasma gondii in complex with inactivator
    32% identity, 86% coverage of query (172 bits)

5dj9A Crystal structure of the ornithine aminotransferase from toxoplasma gondii me49 in a complex with gabaculine
    32% identity, 86% coverage of query (172 bits)

1d7vA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with nma
    33% identity, 87% coverage of query (164 bits)

1d7uA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with lcs
    33% identity, 87% coverage of query (164 bits)

1d7sA Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with dcs
    33% identity, 87% coverage of query (164 bits)

1d7rA / P16932 Crystal structure of the complex of 2,2-dialkylglycine decarboxylase with 5pa (see paper)
    33% identity, 87% coverage of query (164 bits)

1dgdA An alkali metal ion size-dependent switch in the active site structure of dialkylglycine decarboxylase
    33% identity, 87% coverage of query (163 bits)

1zobA Crystal structure of dialkylglycine decarboxylases bound with calcium ion
    33% identity, 87% coverage of query (160 bits)

1zc9A The crystal structure of dialkylglycine decarboxylase complex with pyridoxamine 5-phosphate
    33% identity, 87% coverage of query (160 bits)

1m0qA Structure of dialkylglycine decarboxylase complexed with s-1- aminoethanephosphonate
    33% identity, 87% coverage of query (160 bits)

1m0pA Structure of dialkylglycine decarboxylase complexed with 1-amino-1- phenylethanephosphonate
    33% identity, 87% coverage of query (160 bits)

1m0oA Structure of dialkylglycine decarboxylase complexed with 1-amino-1- methylpropanephosphonate
    33% identity, 87% coverage of query (160 bits)

1m0nA Structure of dialkylglycine decarboxylase complexed with 1- aminocyclopentanephosphonate
    33% identity, 87% coverage of query (160 bits)

4ppmA / A0A0J9X1Q5 Crystal structure of pige: a transaminase involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (map) from serratia sp. Fs14 (see paper)
    31% identity, 88% coverage of query (160 bits)

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Build an alignment for PP_0372 and 100 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory