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Searching for up to 100 curated homologs for PP_1073 FitnessBrowser__Putida:PP_1073 (514 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

Removed hits that are identical to the query, leaving 23

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

glpD glycerol-3-phosphate dehydrogenase; EC 1.1.5.3 from Pseudomonas aeruginosa (see paper)
    72% identity, 100% coverage of query (728 bits)

GlyD / b3426 aerobic glycerol 3-phosphate dehydrogenase (EC 1.1.5.3) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
glpD / P13035 aerobic glycerol 3-phosphate dehydrogenase (EC 1.1.5.3) from Escherichia coli (strain K12) (see 10 papers)
P13035 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Escherichia coli (see paper)
2qcuB / P13035 Crystal structure of glycerol-3-phosphate dehydrogenase from escherichia coli (see paper)
glpD glycerol-3-phosphate dehydrogenase; EC 1.1.5.3 from Escherichia coli K12 (see 6 papers)
glpD / AAA24636.1 glycerophosphate dehydrogenase from Escherichia coli (see paper)
    56% identity, 91% coverage of query (514 bits)

2r46A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phosphopyruvic acid.
    57% identity, 90% coverage of query (513 bits)

2r45A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phospho-d-glyceric acid
    57% identity, 90% coverage of query (513 bits)

eryB / Q2YIQ2 D-erythritol 1-phosphate dehydrogenase (EC 1.1.1.402) from Brucella abortus (strain 2308) (see 3 papers)
ERYB_BRUA2 / Q2YIQ2 D-erythritol 1-phosphate dehydrogenase; EC 1.1.1.402 from Brucella abortus (strain 2308) (see 3 papers)
    51% identity, 97% coverage of query (484 bits)

SMc02520 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Sinorhizobium meliloti 1021
    50% identity, 95% coverage of query (440 bits)

glpD / Q5HPP0 aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Staphylococcus epidermidis (strain ATCC 35984 / RP62A) (see paper)
    30% identity, 83% coverage of query (173 bits)

Build an alignment

Build an alignment for PP_1073 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

GPDH_ENCCU / Q8SR40 Probable glycerol-3-phosphate dehydrogenase; GPDH; EC 1.1.5.3 from Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) (see paper)
    28% identity, 98% coverage of query (170 bits)

GLPD_BACSU / P18158 Aerobic glycerol-3-phosphate dehydrogenase; EC 1.1.5.3 from Bacillus subtilis (strain 168) (see paper)
    30% identity, 92% coverage of query (169 bits)

glpD / CAA74430.1 glycerol-3-phosphate dehydrogenase from Bacillus subtilis (see 3 papers)
    30% identity, 92% coverage of query (168 bits)

GPD2 / P43304 mitochondrial glycerol-3-phosphate dehydrogenase subunit (EC 1.1.5.3) from Homo sapiens (see 8 papers)
GPDM_HUMAN / P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mitohondrial glycerophosphate dehydrogenase gene; mGDH; mtGPD; EC 1.1.5.3 from Homo sapiens (Human) (see paper)
P43304 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Homo sapiens (see 2 papers)
    28% identity, 96% coverage of query (165 bits)

AT3g10370 / Q9SS48 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Arabidopsis thaliana (see paper)
SDP6_ARATH / Q9SS48 Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial; Protein SUGAR-DEPENDENT 6; EC 1.1.5.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    30% identity, 94% coverage of query (157 bits)

Q64521 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Mus musculus (see 3 papers)
    28% identity, 96% coverage of query (150 bits)

P35571 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Rattus norvegicus (see 4 papers)
    29% identity, 96% coverage of query (148 bits)

glpO / O86963 glycerol-3-phosphate oxidase (EC 1.1.3.21) from Enterococcus casseliflavus (see 3 papers)
GLPO_ENTCA / O86963 Alpha-glycerophosphate oxidase; Glycerol-3-phosphate oxidase; EC 1.1.3.21 from Enterococcus casseliflavus (Enterococcus flavescens) (see paper)
    28% identity, 92% coverage of query (144 bits)

Q06B39 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) from Dunaliella salina (see paper)
    28% identity, 97% coverage of query (139 bits)

Q833L7 glycerol-3-phosphate oxidase (EC 1.1.3.21) from Enterococcus faecalis (see paper)
    28% identity, 88% coverage of query (137 bits)

GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial from Candida albicans (see paper)
    28% identity, 93% coverage of query (131 bits)

GUT2 / P32191 glycerol-3-phosphate dehydrogenase (EC 1.1.1.8; EC 1.1.1.94; EC 1.1.5.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 23 papers)
GPDM_YEAST / P32191 Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; EC 1.1.5.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    28% identity, 78% coverage of query (131 bits)

3da1A / Q9KDW6 X-ray structure of the glycerol-3-phosphate dehydrogenase from bacillus halodurans complexed with fad. Northeast structural genomics consortium target bhr167.
    27% identity, 88% coverage of query (120 bits)

GlpA / b2241 anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
glpA / P0A9C0 anaerobic glycerol-3-phosphate dehydrogenase subunit A (EC 1.1.5.3) from Escherichia coli (strain K12) (see 8 papers)
    29% identity, 91% coverage of query (100 bits)

GLPA1_HALVD / D4GYI2 Anaerobic glycerol-3-phosphate dehydrogenase subunit A1; G-3-P dehydrogenase A1; G3PDH A1; EC 1.1.5.3 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    27% identity, 80% coverage of query (92.8 bits)

GLPA2_HALVD / D4GQU6 Anaerobic glycerol-3-phosphate dehydrogenase subunit A2; G-3-P dehydrogenase A2; G3PDH A2; EC 1.1.5.3 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    27% identity, 83% coverage of query (74.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory