Searching for up to 100 curated homologs for PP_1256 FitnessBrowser__Putida:PP_1256 (525 a.a.)
Found high-coverage hits (≥70%) to 61 curated proteins.
Removed hits that are identical to the query, leaving 60
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
KGSD2_AZOBR / Q08IC0 Alpha-ketoglutaric semialdehyde dehydrogenase 2; alphaKGSA dehydrogenase 2; 2,5-dioxovalerate dehydrogenase 2; KGSADH-II; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IC0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
63% identity, 100% coverage of query (617 bits)
KGSD3_AZOBR / Q08IB7 Alpha-ketoglutaric semialdehyde dehydrogenase 3; alphaKGSA dehydrogenase 3; 2,5-dioxovalerate dehydrogenase 3; KGSADH-III; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IB7 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
64% identity, 99% coverage of query (613 bits)
Ga0059261_1896 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Sphingomonas koreensis DSMZ 15582
59% identity, 97% coverage of query (541 bits)
Q88GW5 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Pseudomonas putida (see paper)
54% identity, 100% coverage of query (509 bits)
ACIAD0131 / Q6FFQ0 α-ketoglutarate semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
KGSDH_ACIAD / Q6FFQ0 Alpha-ketoglutaric semialdehyde dehydrogenase; alphaKGSA dehydrogenase; 2,5-dioxovalerate dehydrogenase; EC 1.2.1.26 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Acinetobacter baylyi (see paper)
53% identity, 98% coverage of query (504 bits)
PS417_11015 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas simiae WCS417
53% identity, 99% coverage of query (500 bits)
kgsD / Q9I1Q0 2-ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
53% identity, 98% coverage of query (496 bits)
Pf6N2E2_612 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas fluorescens FW300-N2E2
53% identity, 98% coverage of query (495 bits)
HSERO_RS00735 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Herbaspirillum seropedicae SmR1
52% identity, 99% coverage of query (495 bits)
aldH / AAA89078.1 fatty aldehyde dehydrogenase from Vibrio harveyi (see paper)
49% identity, 96% coverage of query (463 bits)
1eyyA / Q56694 Crystal structure of the NADP+ dependent aldehyde dehydrogenase from vibrio harveyi. (see paper)
49% identity, 96% coverage of query (462 bits)
Build an alignment for PP_1256 and 11 homologs with ≥ 30% identity
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padA / CAA66106.1 phenylacetaldehyde dehydrogenase from Escherichia coli (see paper)
29% identity, 85% coverage of query (89.7 bits)
YdbG / b1385 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
feaB / P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (strain K12) (see 10 papers)
P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (see 3 papers)
29% identity, 85% coverage of query (87.4 bits)
A0A0A7PB40 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Sphingopyxis fribergensis (see paper)
29% identity, 82% coverage of query (81.6 bits)
G7VCG0 aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Pyrobaculum ferrireducens (see paper)
26% identity, 82% coverage of query (81.6 bits)
BETB_PSEAE / Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HTJ1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Pseudomonas aeruginosa (see 5 papers)
28% identity, 81% coverage of query (81.3 bits)
4cazA / Q9HTJ1 Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
28% identity, 81% coverage of query (81.3 bits)
5ek6A Thermostable aldehyde dehydrogenase from pyrobaculum sp. 1860 complexed with NADP and isobutyraldehyde
26% identity, 82% coverage of query (81.3 bits)
4h73A Thermostable aldehyde dehydrogenase from pyrobaculum sp. Complexed with NADP+
26% identity, 82% coverage of query (81.3 bits)
2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct.
28% identity, 81% coverage of query (81.3 bits)
2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa
28% identity, 81% coverage of query (81.3 bits)
5ekcE / G7VCG0 Thermostable aldehyde dehydrogenase from pyrobaculum sp.1860 complexed with NADP+
26% identity, 82% coverage of query (80.9 bits)
tsaD / P94682 TsaD (EC 1.2.1.62) from Comamonas testosteroni (see paper)
TSAD1_COMTE / P94682 4-(hydroxymethyl)benzenesulfonate dehydrogenase TsaD1; Toluenesulfonate aldehyde dehydrogenase TsaD; EC 1.1.1.257 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
27% identity, 89% coverage of query (80.9 bits)
pnpD / C6FI42 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Pseudomonas putida (see paper)
27% identity, 73% coverage of query (79.7 bits)
Q155V4 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda salsa (see paper)
Q8W5A1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda liaotungensis (see 2 papers)
24% identity, 83% coverage of query (76.6 bits)
ROCA2_BACSU / P94391 1-pyrroline-5-carboxylate dehydrogenase 2; P5C dehydrogenase 2; L-glutamate gamma-semialdehyde dehydrogenase; EC 1.2.1.88 from Bacillus subtilis (strain 168) (see 3 papers)
24% identity, 88% coverage of query (76.6 bits)
aldB / AAC13644.1 NAD-dependent chloroacetaldehyde dehydrogenase from Xanthobacter autotrophicus (see paper)
28% identity, 86% coverage of query (76.6 bits)
PatD / b1444 γ-aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
patD / P77674 γ-aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Escherichia coli (strain K12) (see 12 papers)
ABDH_ECOLI / P77674 Gamma-aminobutyraldehyde dehydrogenase; ABALDH; 1-pyrroline dehydrogenase; 4-aminobutanal dehydrogenase; 5-aminopentanal dehydrogenase; EC 1.2.1.19; EC 1.2.1.- from Escherichia coli (strain K12) (see 6 papers)
P77674 aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Escherichia coli (see paper)
28% identity, 88% coverage of query (75.9 bits)
1wnbA / P77674 Escherichia coli ydcw gene product is a medium-chain aldehyde dehydrogenase (complexed with nadh and betaine aldehyde) (see paper)
28% identity, 88% coverage of query (75.5 bits)
1wndA Escherichia coli ydcw gene product is a medium-chain aldehyde dehydrogenase as determined by kinetics and crystal structure
28% identity, 88% coverage of query (75.5 bits)
1wnbB Escherichia coli ydcw gene product is a medium-chain aldehyde dehydrogenase (complexed with nadh and betaine aldehyde)
28% identity, 88% coverage of query (75.5 bits)
XYLG / AAC44160.1 2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate dehydrogenase from Cycloclasticus oligotrophus (see paper)
23% identity, 77% coverage of query (75.1 bits)
BADH2_ORYSI / B3VMC0 Betaine aldehyde dehydrogenase 2; BADH 2; EC 1.2.1.8 from Oryza sativa subsp. indica (Rice) (see paper)
BADH2_ORYSJ / Q84LK3 Betaine aldehyde dehydrogenase 2; OsBADH2; EC 1.2.1.8 from Oryza sativa subsp. japonica (Rice) (see 6 papers)
B3VMC0 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Oryza sativa (see paper)
Q84LK3 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Oryza sativa (see 2 papers)
25% identity, 74% coverage of query (75.1 bits)
BADH_SPIOL / P17202 Aminoaldehyde dehydrogenase BADH; 4-trimethylammoniobutyraldehyde dehydrogenase BADH; Aminobutyraldehyde dehydrogenase BADH; Betaine aldehyde dehydrogenase; SoBADH; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.8 from Spinacia oleracea (Spinach) (see 5 papers)
P17202 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Spinacia oleracea (see 3 papers)
24% identity, 84% coverage of query (74.3 bits)
5ur2B / Q6MNK1 Crystal structure of proline utilization a (puta) from bdellovibrio bacteriovorus inactivated by n-propargylglycine (see paper)
25% identity, 94% coverage of query (73.6 bits)
2d4eC / Q5SJP9 Crystal structure of the hpcc from thermus thermophilus hb8
24% identity, 85% coverage of query (72.4 bits)
4neaA / A0A0H2X0S3 1.90 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus in complex with NAD+ and bme-free cys289 (see paper)
25% identity, 72% coverage of query (72.0 bits)
Q9L4P8 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Staphylococcus aureus (see paper)
25% identity, 72% coverage of query (72.0 bits)
F8TW85 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Sphingomonas sp. (see paper)
25% identity, 92% coverage of query (71.6 bits)
4go4A / C1I208 Crystal structure of pnpe in complex with nicotinamide adenine dinucleotide
26% identity, 71% coverage of query (68.2 bits)
ALDH9A1 / P49189 aldehyde dehydrogenase, E3 isozyme (EC 1.2.1.19; EC 1.2.1.3; EC 1.2.1.47) from Homo sapiens (see 3 papers)
AL9A1_HUMAN / P49189 4-trimethylaminobutyraldehyde dehydrogenase; TMABA-DH; TMABALDH; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; Formaldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; EC 1.2.1.47; EC 1.2.1.3; EC 1.2.1.46; EC 1.2.1.19 from Homo sapiens (Human) (see 5 papers)
P49189 4-trimethylammoniobutyraldehyde dehydrogenase (EC 1.2.1.47) from Homo sapiens (see 4 papers)
25% identity, 78% coverage of query (65.5 bits)
6vr6D / P49189 Structure of aldh9a1 complexed with NAD+ in space group p1 (see paper)
25% identity, 78% coverage of query (65.5 bits)
4f3xA / Q92ND9 Crystal structure of putative aldehyde dehydrogenase from sinorhizobium meliloti 1021 complexed with NAD
24% identity, 88% coverage of query (60.5 bits)
4o6rA / B4EJX1 Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
24% identity, 79% coverage of query (60.1 bits)
AL2C4_ARATH / Q56YU0 Aldehyde dehydrogenase family 2 member C4; ALDH1a; Protein REDUCED EPIDERMAL FLUORESCENCE 1; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
25% identity, 86% coverage of query (59.3 bits)
ALDH8A1 / Q9H2A2 aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Homo sapiens (see 2 papers)
AL8A1_HUMAN / Q9H2A2 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; Aldehyde dehydrogenase family 8 member A1; EC 1.2.1.32 from Homo sapiens (Human) (see 2 papers)
Q9H2A2 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Homo sapiens (see 2 papers)
23% identity, 83% coverage of query (58.9 bits)
8hapB Crystal structure of thermostable acetaldehyde dehydrogenase from hyperthermophilic archaeon sulfolobus tokodaii
22% identity, 77% coverage of query (58.5 bits)
8hapA / Q976X5 Crystal structure of thermostable acetaldehyde dehydrogenase from hyperthermophilic archaeon sulfolobus tokodaii (see paper)
22% identity, 77% coverage of query (58.5 bits)
3iwkH / Q8VWZ1 Crystal structure of aminoaldehyde dehydrogenase 1 from pisum sativum (psamadh1) (see paper)
23% identity, 74% coverage of query (54.3 bits)
AADH1_PEA / Q8VWZ1 Aminoaldehyde dehydrogenase 1, peroxisomal; PsAMADH1; Aminobutyraldehyde dehydrogenase AMADH1; Gamma-guanidinobutyraldehyde dehydrogenase AMADH1; EC 1.2.1.-; EC 1.2.1.19; EC 1.2.1.54 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see paper)
Q8VWZ1 aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Pisum sativum (see 3 papers)
23% identity, 74% coverage of query (54.3 bits)
AL9A1_GADMC / P56533 4-trimethylaminobutyraldehyde dehydrogenase; TMABA-DH; TMABADH; Aldehyde dehydrogenase family 9 member A1; Betaine aldehyde dehydrogenase; BADH; EC 1.2.1.47; EC 1.2.1.3 from Gadus morhua subsp. callarias (Baltic cod) (Gadus callarias) (see paper)
1bpwA / P56533 Betaine aldehyde dehydrogenase from cod liver (see paper)
25% identity, 78% coverage of query (53.1 bits)
6popA Crystal structure of daua in complex with NADP+ (see paper)
23% identity, 86% coverage of query (52.8 bits)
1uxuA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 77% coverage of query (51.6 bits)
1uxtA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 77% coverage of query (51.6 bits)
1uxrA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 77% coverage of query (51.6 bits)
1uxqA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 77% coverage of query (51.6 bits)
1uxnA Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (gapn) from thermoproteus tenax
25% identity, 77% coverage of query (51.6 bits)
1ky8A / O57693 Crystal structure of the non-phosphorylating glyceraldehyde-3- phosphate dehydrogenase (see paper)
25% identity, 77% coverage of query (50.1 bits)
GAPN_THETE / O57693 NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; Glyceraldehyde phosphate dehydrogenase (NAD(P)); GAPN; EC 1.2.1.90 from Thermoproteus tenax (see 4 papers)
O57693 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (EC 1.2.1.90) from Thermoproteus tenax (see 4 papers)
25% identity, 77% coverage of query (50.1 bits)
6vwfA / P49189 Structure of aldh9a1 complexed with NAD+ in space group c222 (see paper)
23% identity, 78% coverage of query (47.8 bits)
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