Searching for up to 100 curated homologs for PP_2368 FitnessBrowser__Putida:PP_2368 (267 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
DkgB / b0207 methylglyoxal reductase DkgB (EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dkgB / P30863 methylglyoxal reductase DkgB (EC 1.1.1.21; EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli (strain K12) (see 5 papers)
dkgB / MB|P30863 2,5-diketo-D-gluconic acid reductase B; EC 1.1.1.274 from Escherichia coli K12 (see 5 papers)
67% identity, 100% coverage of query (370 bits)
A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
41% identity, 97% coverage of query (187 bits)
DkgA / b3012 methylglyoxal reductase DkgA (EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
dkgA / Q46857 methylglyoxal reductase DkgA (EC 1.1.1.21; EC 1.1.1.346) from Escherichia coli (strain K12) (see 9 papers)
Q46857 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Escherichia coli (see paper)
39% identity, 97% coverage of query (175 bits)
Q5FT75 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
39% identity, 95% coverage of query (174 bits)
3wbwA / Q5FT75 Crystal structure of gox0644 in complex with NADPH
39% identity, 95% coverage of query (174 bits)
A0A3P3ZE14 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania braziliensis (see paper)
38% identity, 96% coverage of query (170 bits)
PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major (see paper)
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major (see paper)
37% identity, 97% coverage of query (170 bits)
4g5dA / P22045 X-ray crystal structure of prostaglandin f synthase from leishmania major friedlin bound to NADPH (see paper)
37% identity, 97% coverage of query (170 bits)
AKR_SYNY3 / P74308 Aldo/keto reductase slr0942; AKR; AKR3G1; EC 1.1.1.184 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
40% identity, 97% coverage of query (169 bits)
H9CWC0 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) (EC 1.1.1.274) from Corynebacterium glutamicum (see paper)
41% identity, 95% coverage of query (168 bits)
2wzmA / A0QV09 Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form (see paper)
39% identity, 97% coverage of query (167 bits)
Y2407_MYCS2 / A0QV09 Aldo-keto reductase MSMEG_2407/MSMEI_2346; AKR; AKR5H1; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
39% identity, 97% coverage of query (167 bits)
A2T1W7 aldose reductase (EC 1.1.1.21) from Zea mays (see 2 papers)
36% identity, 99% coverage of query (167 bits)
4gieA / Q4DJ07 Crystal structure of prostaglandin f synthase from trypanosoma cruzi bound to NADP (see paper)
36% identity, 99% coverage of query (167 bits)
5jh2A / A2T1W7 Crystal structure of the holo form of akr4c7 from maize (see paper)
37% identity, 94% coverage of query (167 bits)
4fziA Crystal structure of prostaglandin f synthase from trypanosoma cruzi
36% identity, 99% coverage of query (167 bits)
Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi (see paper)
36% identity, 99% coverage of query (166 bits)
yvgN / O32210 glyoxal/methylglyoxal reductase (EC 1.1.1.283; EC 1.1.1.91) from Bacillus subtilis (strain 168) (see 3 papers)
GR_BACSU / O32210 Glyoxal reductase; GR; Methylglyoxal reductase; EC 1.1.1.-; EC 1.1.1.283 from Bacillus subtilis (strain 168) (see paper)
40% identity, 97% coverage of query (166 bits)
3d3fA / O32210 Crystal structure of yvgn and cofactor NADPH from bacillus subtilis (see paper)
40% identity, 97% coverage of query (166 bits)
YPR1_YEAST / Q12458 Putative reductase 1; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
37% identity, 94% coverage of query (164 bits)
Y2996_MYCBO / Q7TXI6 Aldo-keto reductase BQ2027_MB2996; EC 1.1.1.- from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
40% identity, 98% coverage of query (164 bits)
Y2971_MYCTU / P9WQA5 Aldo-keto reductase Rv2971; AKR; EC 1.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
40% identity, 98% coverage of query (164 bits)
E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria) (see paper)
3b3dA / O34678 B.Subtilis ytbe (see paper)
39% identity, 97% coverage of query (163 bits)
7s5fB / A0A1U9WT24 Crystal structure of mannose-6-phosphate reductase from celery (apium graveolens) leaves with NADP+ and mannonic acid bound (see paper)
34% identity, 97% coverage of query (163 bits)
M6PR / P92923 mannose 6-phosphate reductase (EC 1.1.1.224) from Apium graveolens (see paper)
P92923 mannose-6-phosphate 6-reductase (EC 1.1.1.224) from Apium graveolens (see paper)
33% identity, 97% coverage of query (162 bits)
A6PR / P28475 aldose-6-phosphate reductase subunit (EC 1.1.1.200) from Malus domestica (see 2 papers)
P28475 aldose-6-phosphate reductase (NADPH) (EC 1.1.1.200) from Malus domestica (see paper)
34% identity, 99% coverage of query (162 bits)
BN592_00768 / R7AF73 NAD(P)-dependent bile acid 3β-dehydrogenase (EC 1.1.1.391) from Eggerthella sp. CAG:298 (see 2 papers)
R7AF73 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270) from Eggerthella sp. CAG:298 (see paper)
36% identity, 94% coverage of query (160 bits)
GCY1_YEAST / P14065 Glycerol 2-dehydrogenase (NADP(+)); Galactose-inducible crystallin-like protein 1; EC 1.1.1.156 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
35% identity, 95% coverage of query (159 bits)
P80508 Prostaglandin-E(2) 9-reductase; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; EC 1.1.1.189; EC 1.1.1.149 from Oryctolagus cuniculus (Rabbit)
35% identity, 97% coverage of query (159 bits)
1q13A / P80508 Crystal structure of rabbit 20alpha hyroxysteroid dehydrogenase in ternary complex with NADP and testosterone (see paper)
35% identity, 97% coverage of query (158 bits)
3wczA / H9JTG9 Crystal structure of bombyx mori aldo-keto reductase (akr2e4) in complex with NADP (see paper)
37% identity, 95% coverage of query (158 bits)
AK2E4_BOMMO / H9JTG9 Aldo-keto reductase AKR2E4; 3-dehydroecdysone reductase; Aldo-keto reductase 2E; EC 1.1.1.- from Bombyx mori (Silk moth) (see paper)
37% identity, 95% coverage of query (158 bits)
1q5mA Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH
35% identity, 97% coverage of query (158 bits)
AKR4C9 / Q0PGJ6 aldo-keto reductase family 4 member C9 (EC 1.1.1.21; EC 1.1.1.210; EC 1.1.1.2; EC 1.1.1.54) from Arabidopsis thaliana (see 2 papers)
AKRC9_ARATH / Q0PGJ6 NADPH-dependent aldo-keto reductase, chloroplastic; AtChlAKR; Aldo-keto reductase family 4 member C9; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
35% identity, 93% coverage of query (157 bits)
3h7uA / Q0PGJ6 Crystal structure of the plant stress-response enzyme akr4c9 (see paper)
35% identity, 93% coverage of query (157 bits)
Q2TJA5 prostaglandin-F synthase (EC 1.1.1.188) from Sus scrofa (see paper)
37% identity, 95% coverage of query (157 bits)
AK1C1_MACFU / Q95JH6 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fuscata fuscata (Japanese macaque) (see paper)
34% identity, 98% coverage of query (156 bits)
AK1CA_RAT / D3ZF77 Aldo-keto reductase family 1 member C15; RAKc; EC 1.1.1.-; EC 1.1.1.216 from Rattus norvegicus (Rat) (see 4 papers)
36% identity, 95% coverage of query (155 bits)
I7HD84 D-xylose reductase (EC 1.1.1.307) from Rhizomucor pusillus (see paper)
33% identity, 96% coverage of query (155 bits)
4l1wA / P52895 Crystal structuer of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+ and progesterone (see paper)
34% identity, 98% coverage of query (154 bits)
xyrB / A2QQ97 D-xylose reductase XyrB (EC 1.1.1.21; EC 1.1.1.431) from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 4 papers)
36% identity, 97% coverage of query (154 bits)
AKR1C2 / P52895 3α hydroxysteroid dehydrogenase III (EC 1.1.1.52; EC 1.1.1.395; EC 1.1.1.213; EC 1.1.1.357) from Homo sapiens (see 12 papers)
AK1C2_HUMAN / P52895 Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Type III 3-alpha-hydroxysteroid dehydrogenase; EC 1.-.-.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.357 from Homo sapiens (Human) (see 9 papers)
P52895 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 9 papers)
34% identity, 98% coverage of query (154 bits)
AK1C1_MACFA / Q95JH7 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
34% identity, 98% coverage of query (154 bits)
Q95JH5 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Macaca fascicularis (see paper)
34% identity, 97% coverage of query (154 bits)
4xo6B Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
34% identity, 98% coverage of query (154 bits)
4xo6A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
34% identity, 98% coverage of query (154 bits)
1xjbA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h), citrate and acetate molecules
34% identity, 98% coverage of query (154 bits)
4jtrB Akr1c2 complex with ibuprofen
34% identity, 98% coverage of query (154 bits)
1ihiA Crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with NADP+ and ursodeoxycholate
34% identity, 98% coverage of query (154 bits)
4jtrA Akr1c2 complex with ibuprofen
34% identity, 98% coverage of query (154 bits)
4jtqA Akr1c2 complex with flurbiprofen
34% identity, 98% coverage of query (154 bits)
4jqaA Akr1c2 complex with mefenamic acid
34% identity, 98% coverage of query (154 bits)
4jq4A Akr1c2 complex with indomethacin
34% identity, 98% coverage of query (154 bits)
4jq3A Akr1c2 complex with zomepirac
34% identity, 98% coverage of query (154 bits)
4jq2A Akr1c2 complex with sulindac
34% identity, 98% coverage of query (154 bits)
4jq1A Akr1c2 complex with naproxen
34% identity, 98% coverage of query (154 bits)
4xo7A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
34% identity, 98% coverage of query (154 bits)
2hdjA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h)
34% identity, 98% coverage of query (154 bits)
1j96A Human 3alpha-hsd type 3 in ternary complex with NADP and testosterone
34% identity, 98% coverage of query (154 bits)
1xf0A Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (akr1c3) complexed with delta4-androstene-3,17-dione and NADP
34% identity, 98% coverage of query (153 bits)
AK1C4_MACFU / Q95JH4 Aldo-keto reductase family 1 member C4; 3-alpha-hydroxysteroid dehydrogenase type I; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; Chlordecone reductase homolog; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.225 from Macaca fuscata fuscata (Japanese macaque) (see paper)
34% identity, 97% coverage of query (152 bits)
D0VDT4 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Bos taurus (see paper)
35% identity, 95% coverage of query (152 bits)
AKR1C4 / P17516 aldo-keto reductase family 1 member C4 (EC 1.1.1.213; EC 1.3.1.20; EC 1.1.1.225; EC 1.1.1.357) from Homo sapiens (see 9 papers)
AK1C4_HUMAN / P17516 Aldo-keto reductase family 1 member C4; 3-alpha-hydroxysteroid dehydrogenase type I; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; Chlordecone reductase; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.225 from Homo sapiens (Human) (see 11 papers)
P17516 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Homo sapiens (see 4 papers)
34% identity, 97% coverage of query (152 bits)
AKR1C1 / Q04828 aldo-keto reductase family 1 member C1 (EC 1.1.1.149; EC 1.1.1.213; EC 1.1.1.112; EC 1.3.1.20) from Homo sapiens (see 13 papers)
AK1C1_HUMAN / Q04828 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1; DD1; High-affinity hepatic bile acid-binding protein; HBAB; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Homo sapiens (Human) (see 8 papers)
Q04828 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 13 papers)
33% identity, 98% coverage of query (152 bits)
4fa3A Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (r)-1-(naphthalen-2-ylsulfonyl)piperidine-3- carboxylic acid (86)
34% identity, 98% coverage of query (152 bits)
3gugA Crystal structure of akr1c1 l308v mutant in complex with NADP and 3,5- dichlorosalicylic acid
33% identity, 98% coverage of query (152 bits)
4h7cA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 1-{4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl}-2- pyrrolidinone
34% identity, 98% coverage of query (152 bits)
6ijxA Crystal structure of akr1c1 complexed with meclofenamic acid
33% identity, 98% coverage of query (152 bits)
6a7aA Akr1c1 complexed with new inhibitor with novel scaffold
33% identity, 98% coverage of query (152 bits)
4yvpA Crystal structure of akr1c1 complexed with glibenclamide
33% identity, 98% coverage of query (152 bits)
3ntyA Crystal structure of akr1c1 in complex with NADP and 5-phenyl,3- chlorosalicylic acid
33% identity, 98% coverage of query (152 bits)
3c3uA Crystal structure of akr1c1 in complex with NADP and 3,5- dichlorosalicylic acid
33% identity, 98% coverage of query (152 bits)
2ipjA Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant y24a in complex with NADP+ and epi-testosterone
34% identity, 98% coverage of query (152 bits)
xyl1 / Q876L8 aldose reductase (EC 1.1.1.21; EC 1.1.1.431) from Hypocrea jecorina (see 2 papers)
XYL1_HYPJE / Q876L8 NAD(P)H-dependent D-xylose reductase xyl1; XR; EC 1.1.1.- from Hypocrea jecorina (Trichoderma reesei) (see paper)
Q876L8 D-xylose reductase (EC 1.1.1.307) from Trichoderma reesei (see paper)
33% identity, 96% coverage of query (151 bits)
2fvlA / P17516 Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (akr1c4) complexed with NADP+
34% identity, 97% coverage of query (151 bits)
Akr1a4 / Q9JII6 alcohol dehydrogenase [NADP+] (EC 1.1.1.19) from Mus musculus (see 4 papers)
AK1A1_MOUSE / Q9JII6 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Mus musculus (Mouse) (see 5 papers)
Q540D7 aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Mus musculus (see paper)
Q9JII6 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mus musculus (see paper)
32% identity, 96% coverage of query (151 bits)
T2HVB4 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Oryctolagus cuniculus (see paper)
33% identity, 95% coverage of query (151 bits)
1vbjA / Q9GV41 The crystal structure of prostaglandin f synthase from trypanosoma brucei
36% identity, 97% coverage of query (151 bits)
PGFS_TRYBB / Q9GV41 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Trypanosoma brucei brucei (see paper)
36% identity, 97% coverage of query (151 bits)
AK1CN_HORSE / Q1XAA8 Aldo-keto reductase family 1 member C23; EC 1.1.1.- from Equus caballus (Horse) (see paper)
Q1XAA8 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Equus caballus (see paper)
33% identity, 98% coverage of query (150 bits)
ALDX_SPOSA / P27800 Aldehyde reductase 1; ALR 1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase I; EC 1.1.1.2 from Sporidiobolus salmonicolor (Yeast-like fungus) (Sporobolomyces salmonicolor) (see 2 papers)
AAB17362.1 NADPH-dependent aldehyde reductase from Sporidiobolus salmonicolor (see paper)
34% identity, 98% coverage of query (150 bits)
AR-h / CAA88322.1 aldose reductase from Hordeum vulgare (see paper)
34% identity, 95% coverage of query (150 bits)
Q5FYA7 prostaglandin-F synthase (EC 1.1.1.188) from Canis lupus familiaris (see 2 papers)
35% identity, 97% coverage of query (150 bits)
7f7kB / A0A5J6VLZ7 Crystal structure of akr4c17 bound with NADP+
37% identity, 94% coverage of query (150 bits)
2bgsA / P23901 Holo aldose reductase from barley (see paper)
34% identity, 95% coverage of query (150 bits)
GCY1 putative uncharacterized protein from Candida albicans (see paper)
37% identity, 96% coverage of query (150 bits)
AKR1E2 / P82125 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) from Sus scrofa (see paper)
AKCL2_PIG / P82125 1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; Aldo-keto reductase family 1 member E2; EC 1.1.1.263 from Sus scrofa (Pig) (see paper)
36% identity, 95% coverage of query (150 bits)
ALRA_DICDI / Q6IMN8 Aldose reductase A; ARA; Aldehyde reductase A; AlrA; EC 1.1.1.21 from Dictyostelium discoideum (Social amoeba) (see paper)
Q6IMN8 methylglyoxal reductase (NADPH) (EC 1.1.1.283) from Dictyostelium discoideum (see paper)
32% identity, 96% coverage of query (150 bits)
4zfcB / P42330 Crystal structure of akr1c3 complexed with glicazide (see paper)
34% identity, 98% coverage of query (150 bits)
AKR1C3 / P42330 aldo-keto reductase family 1 member C3 (EC 1.1.1.64; EC 1.1.1.213; EC 1.1.1.112; EC 1.1.1.357; EC 1.1.1.188) from Homo sapiens (see 15 papers)
AK1C3_HUMAN / P42330 Aldo-keto reductase family 1 member C3; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Prostaglandin F synthase; PGFS; Testosterone 17-beta-dehydrogenase 5; EC 1.1.1.-; EC 1.1.1.210; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.188; EC 1.1.1.239; EC 1.1.1.64 from Homo sapiens (Human) (see 14 papers)
P42330 prostaglandin-F synthase (EC 1.1.1.188); aldose reductase (EC 1.1.1.21); 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.239); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3(or 17)beta-hydroxysteroid dehydrogenase (EC 1.1.1.51); 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62); testosterone 17beta-dehydrogenase (NADP+) (EC 1.1.1.64); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 38 papers)
34% identity, 98% coverage of query (150 bits)
A0A455KZK8 D-xylose reductase (EC 1.1.1.307) from Thermomyces lanuginosus (see paper)
36% identity, 97% coverage of query (150 bits)
3r43A Akr1c3 complexed with mefenamic acid
34% identity, 98% coverage of query (150 bits)
4falA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 3-((3,4-dihydroisoquinolin-2(1h)-yl)sulfonyl)-n- methylbenzamide (80)
34% identity, 98% coverage of query (150 bits)
1zq5A Crystal structure of human androgenic 17beta-hydroxysteroid dehydrogenase type 5 in complexed with a potent inhibitor em1404
34% identity, 98% coverage of query (150 bits)
7f7mA Akr4c17 in complex with NADP+ and glyphosate
37% identity, 94% coverage of query (150 bits)
7f7lA Crystal structure of akr4c17 bound with NADPH
37% identity, 94% coverage of query (150 bits)
3ufyA Akr1c3 complex with r-naproxen
34% identity, 98% coverage of query (150 bits)
3r94A Akr1c3 complex with flurbiprofen
34% identity, 98% coverage of query (150 bits)
3r8hA Akr1c3 complex with zomepirac
34% identity, 98% coverage of query (150 bits)
3r8gA Akr1c3 complex with ibuprofen
34% identity, 98% coverage of query (150 bits)
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Lawrence Berkeley National Laboratory