Searching for up to 100 curated homologs for PP_2784 FitnessBrowser__Putida:PP_2784 (254 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
aknA / Q9L553 aclacinomycin polyketide synthase reductase from Streptomyces galilaeus (see paper)
37% identity, 97% coverage of query (141 bits)
dpsE / Q54812 daunorubicin polyketide synthase reductase from Streptomyces peucetius (see paper)
36% identity, 97% coverage of query (140 bits)
jadE / Q56166 jadomycin biosynthesis oxidoreductase JadE from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see 2 papers)
36% identity, 98% coverage of query (140 bits)
snoaD / CAA12013.1 SnoaD from Streptomyces nogalater (see 3 papers)
35% identity, 97% coverage of query (137 bits)
3sjuA / Q67G28 Hedamycin polyketide ketoreductase bound to NADPH (see paper)
35% identity, 97% coverage of query (134 bits)
2rh4B / P16544 Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin (see paper)
35% identity, 96% coverage of query (133 bits)
C785_RS20555 / A0A2E7P978 2-dehydro-3-deoxy-L-pentonate 4-dehydrogenase (EC 1.1.1.401) from Herbaspirillum sp. (see paper)
36% identity, 97% coverage of query (133 bits)
ACT3_STRCO / P16544 Putative ketoacyl reductase; EC 1.3.1.- from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see 2 papers)
35% identity, 96% coverage of query (133 bits)
1xr3A Actinorhodin polyketide ketoreductase with NADP and the inhibitor isoniazid bound
35% identity, 96% coverage of query (133 bits)
2rh4A Actinorhodin ketoreductase, actkr, with NADPH and inhibitor emodin
35% identity, 96% coverage of query (133 bits)
1w4zA Structure of actinorhodin polyketide (actiii) reductase
35% identity, 96% coverage of query (133 bits)
H281DRAFT_00644 2-deoxy-D-ribonate 3-dehydrogenase from Paraburkholderia bryophila 376MFSha3.1
36% identity, 96% coverage of query (132 bits)
Q767A0 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acidovorax sp. (see paper)
34% identity, 98% coverage of query (131 bits)
A8R3J3 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Ralstonia pickettii (see paper)
34% identity, 96% coverage of query (130 bits)
FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
33% identity, 97% coverage of query (130 bits)
5b4tA / D0VWQ0 Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and a substrate d-3- hydroxybutyrate (see paper)
31% identity, 98% coverage of query (130 bits)
5t5qC / Q2YL80 Crystal structure of short-chain dehydrogenase/reductase sdr:glucose/ribitol dehydrogenase from brucella melitensis
34% identity, 96% coverage of query (130 bits)
3w8dA Crystal structure of d-3-hydroxybutyrate dehydrogenase from alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate
31% identity, 98% coverage of query (130 bits)
3vdrA Crystal structure of d-3-hydroxybutyrate dehydrogenase, prepared in the presence of the substrate d-3-hydroxybutyrate and NAD(+)
31% identity, 98% coverage of query (130 bits)
3vdqA Crystal structure of alcaligenes faecalis d-3-hydroxybutyrate dehydrogenase in complex with NAD(+) and acetate
31% identity, 98% coverage of query (130 bits)
Q2PEN2 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Ralstonia pickettii (see 2 papers)
34% identity, 92% coverage of query (129 bits)
phaB / BAC45231.1 3-keto-acyl-CoA reductase from Bacillus sp. INT005 (see paper)
35% identity, 98% coverage of query (129 bits)
fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
34% identity, 96% coverage of query (129 bits)
4nbuB Crystal structure of fabg from bacillus sp (see paper)
33% identity, 97% coverage of query (128 bits)
4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
34% identity, 97% coverage of query (127 bits)
Q5KST5 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas fragi (see 3 papers)
1wmbA / Q5KST5 Crystal structure of NAD dependent d-3-hydroxybutylate dehydrogenase (see paper)
BAD86668.1 D(-)-3-hydroxybutyrate dehydrogenase from Pseudomonas fragi (see paper)
31% identity, 98% coverage of query (127 bits)
2ztlA Closed conformation of d-3-hydroxybutyrate dehydrogenase complexed with NAD+ and l-3-hydroxybutyrate
31% identity, 98% coverage of query (127 bits)
5yssB / A0A0D7LY80 Crystal structure of aminocaproic acid cyclase in complex with NAD (+) (see paper)
31% identity, 96% coverage of query (126 bits)
4b79A / Q9HWT0 The aeropath project and pseudomonas aeruginosa high-throughput crystallographic studies for assessment of potential targets in early stage drug discovery. (see paper)
36% identity, 96% coverage of query (125 bits)
4iiuA / A0A0H2V833 Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from escherichia coli strain cft073 complexed with NADP+ at 2.1 a resolution
35% identity, 96% coverage of query (124 bits)
Q9AE70 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Pseudomonas putida (see 2 papers)
32% identity, 96% coverage of query (124 bits)
2q2qD / Q9AE70 Structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida (see paper)
32% identity, 96% coverage of query (124 bits)
FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
33% identity, 98% coverage of query (122 bits)
4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
33% identity, 96% coverage of query (122 bits)
Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
33% identity, 96% coverage of query (121 bits)
Q9HK51 aldose 1-dehydrogenase (NAD+) (EC 1.1.1.121) from Thermoplasma acidophilum (see 2 papers)
32% identity, 96% coverage of query (120 bits)
2dteA / Q9HK51 Structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt) in complex with nadh (see paper)
32% identity, 96% coverage of query (120 bits)
BPHYT_RS16120 sorbitol dehydrogenase, D-fructose forming (EC 1.1.1.14) from Burkholderia phytofirmans PsJN
32% identity, 97% coverage of query (120 bits)
PS417_07245 2-deoxy-D-ribonate 3-dehydrogenase from Pseudomonas simiae WCS417
PS417_07245 / A0A1N7UEI0 2-deoxy-D-ribonate dehydrogenase from Pseudomonas simiae (see paper)
30% identity, 95% coverage of query (120 bits)
Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Synechococcus elongatus PCC 7942 = FACHB-805 (see paper)
35% identity, 96% coverage of query (120 bits)
GOLD_LISIN / Q92EU6 NAD-dependent glycerol dehydrogenase; Dha-forming NAD-dependent glycerol dehydrogenase; EC 1.1.1.6 from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) (see paper)
35% identity, 96% coverage of query (120 bits)
Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
32% identity, 96% coverage of query (120 bits)
A0A1E3M3N6 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Acinetobacter baumannii (see paper)
6zzsD / A0A1E3M3N6 Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and 3-oxovalerate (see paper)
32% identity, 96% coverage of query (120 bits)
2dtxA Structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt) in complex with d-mannose
32% identity, 96% coverage of query (120 bits)
3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
33% identity, 96% coverage of query (120 bits)
6zzqA Crystal structure of (r)-3-hydroxybutyrate dehydrogenase from acinetobacter baumannii complexed with NAD+ and acetoacetate
32% identity, 96% coverage of query (119 bits)
chnA / Q5P8S7 cyclohexanol dehydrogenase from Aromatoleum aromaticum (strain EbN1) (see paper)
4ureB / Q5P8S7 Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1 (see paper)
33% identity, 96% coverage of query (118 bits)
BPHYT_RS04775 2-deoxy-D-ribonate 3-dehydrogenase from Burkholderia phytofirmans PsJN
34% identity, 74% coverage of query (118 bits)
4urfB Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1
33% identity, 96% coverage of query (118 bits)
4urfA Molecular genetic and crystal structural analysis of 1-(4- hydroxyphenyl)-ethanol dehydrogenase from aromatoleum aromaticum ebn1
33% identity, 96% coverage of query (118 bits)
6ixmC / X2D0L0 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD (see paper)
32% identity, 96% coverage of query (117 bits)
YohE / b2137 putative oxidoreductase YohF from Escherichia coli K-12 substr. MG1655 (see 5 papers)
33% identity, 95% coverage of query (117 bits)
FABG_SYNY3 / P73574 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
35% identity, 95% coverage of query (117 bits)
YfeF / b2426 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
ucpA / P37440 oxidoreductase UcpA (EC 1.1.1.304) from Escherichia coli (strain K12) (see 6 papers)
35% identity, 98% coverage of query (117 bits)
RUMGNA_00694 / A7AZH2 3β-hydroxysteroid dehydrogenase (EC 1.1.1.393) from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see 4 papers)
3BHDP_RUMGV / A7AZH2 3beta-hydroxysteroid dehydrogenase; 3beta-HSDH; 3beta-hydroxycholanate 3-dehydrogenase (NADP(+)); NADP-dependent bile acid 3beta-dehydrogenase; EC 1.1.1.-; EC 1.1.1.393 from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see paper)
A7AZH2 3beta-hydroxycholanate 3-dehydrogenase (NADP+) (EC 1.1.1.393) from [Ruminococcus] gnavus (see paper)
32% identity, 96% coverage of query (117 bits)
ABA4_BOTFB / A0A384JQF5 Short-chain dehydrogenase/reductase aba4; Abscisic acid biosynthesis cluster protein 4; EC 1.1.1.- from Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) (see 3 papers)
32% identity, 96% coverage of query (117 bits)
ABA4_BOTFU / Q14RS1 Short-chain dehydrogenase/reductase aba4; Abscisic acid biosynthesis cluster protein 4; EC 1.1.1.- from Botryotinia fuckeliana (Noble rot fungus) (Botrytis cinerea) (see 3 papers)
32% identity, 96% coverage of query (116 bits)
Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
32% identity, 96% coverage of query (116 bits)
Build an alignment for PP_2784 and 58 homologs with ≥ 30% identity
Or download the sequences
G0HY85 acetoacetyl-CoA reductase (EC 1.1.1.36) from Haloarcula hispanica (see paper)
29% identity, 95% coverage of query (115 bits)
HSERO_RS19365 2-keto-3-deoxy-L-fuconate 4-dehydrogenase FucDH from Herbaspirillum seropedicae SmR1
33% identity, 96% coverage of query (115 bits)
Q5ZT49 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) from Legionella pneumophila subsp. pneumophila (see paper)
28% identity, 96% coverage of query (115 bits)
5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
34% identity, 96% coverage of query (115 bits)
bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
34% identity, 96% coverage of query (114 bits)
C785_RS13675 / A0A4P7ABK7 2-dehydro-3-deoxy-D-pentonate/2-dehydro-3-deoxy-L-fuconate 4-dehydrogenase (EC 1.1.1.434) from Herbaspirillum huttiense (see paper)
33% identity, 96% coverage of query (114 bits)
7caxD / A0A1K1L6W4 Crystal structure of bacterial reductase
33% identity, 96% coverage of query (114 bits)
7v1qA / U2RWV7 Leifsonia alcohol dehydrogenases lnadh (see paper)
34% identity, 96% coverage of query (114 bits)
AT1G24360 / P33207 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic (EC 1.1.1.100) from Arabidopsis thaliana (see paper)
31% identity, 96% coverage of query (113 bits)
A0A545BBS8 pseudoephedrine dehydrogenase (EC 1.1.1.422) from Arthrobacter sp. TS-15 (see paper)
36% identity, 96% coverage of query (113 bits)
6qheA / A0A545BBS8 Alcohol dehydrogenase from arthrobacter sp. Ts-15 in complex with NAD+
36% identity, 96% coverage of query (113 bits)
C7RM91 acetoacetyl-CoA reductase (EC 1.1.1.36) from Candidatus Accumulibacter phosphatis (see 2 papers)
31% identity, 98% coverage of query (113 bits)
4dmmB / Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase from synechococcus elongatus pcc 7942 in complex with NADP
32% identity, 96% coverage of query (112 bits)
7emgB / A0A0G8B235 Carbonyl reductase variant 4 (r123c/l209p/f183y/v61k) from serratia marcescens complexed with NADP+ (see paper)
31% identity, 96% coverage of query (112 bits)
Atu3164 / A9CES4 galactitol 2-dehydrogenase (EC 1.1.1.16) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
GDH_AGRFC / A9CES4 Galactitol 2-dehydrogenase; GDH; Sorbitol dehydrogenase; SorbD; EC 1.1.1.16; EC 1.1.1.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
31% identity, 96% coverage of query (112 bits)
FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
31% identity, 95% coverage of query (112 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
29% identity, 96% coverage of query (112 bits)
6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
31% identity, 95% coverage of query (111 bits)
1edoA / Q93X62 The x-ray structure of beta-keto acyl carrier protein reductase from brassica napus complexed with NADP+ (see paper)
31% identity, 96% coverage of query (111 bits)
6vspA Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a
28% identity, 97% coverage of query (110 bits)
6xewA Structure of serratia marcescens 2,3-butanediol dehydrogenase
28% identity, 97% coverage of query (110 bits)
6vspB / H9XP47 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a (see paper)
28% identity, 97% coverage of query (110 bits)
budC / H9XP47 meso-butanediol dehydrogenase [(R)-acetoin-forming] (EC 1.1.1.304; EC 1.1.1.76) from Serratia marcescens (see paper)
MBDH_SERMA / H9XP47 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens (see 3 papers)
28% identity, 97% coverage of query (110 bits)
6oz7A / P33368 Putative oxidoreductase from escherichia coli str. K-12
32% identity, 95% coverage of query (110 bits)
5wuwA / A0A192ICX3 Serratia marcescens short-chain dehydrogenase/reductase f98l/f202l mutant (see paper)
32% identity, 97% coverage of query (110 bits)
4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
29% identity, 96% coverage of query (109 bits)
4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
30% identity, 96% coverage of query (109 bits)
6ihhA Crystal structure of rasadh f12 from ralstonia.Sp in complex with NADPH and a6o
29% identity, 96% coverage of query (108 bits)
1iy8A / Q9LBG2 Crystal structure of levodione reductase (see paper)
31% identity, 96% coverage of query (108 bits)
Q9LBG2 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum)
31% identity, 96% coverage of query (108 bits)
3rwbA Crystal structure of complex of 4pal (4-pyridoxolactone) and pldh (tetrameric pyridoxal 4-dehydrogenase) from mesorhizobium loti
31% identity, 96% coverage of query (108 bits)
3ndrA / Q988B7 Crystal structure of tetrameric pyridoxal 4-dehydrogenase from mesorhizobium loti
31% identity, 96% coverage of query (108 bits)
2d1yA Crystal structure of tt0321 from thermus thermophilus hb8
35% identity, 96% coverage of query (108 bits)
C0IR58 aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Ralstonia sp. (see paper)
4bmsF / C0IR58 Short chain alcohol dehydrogenase from ralstonia sp. Dsm 6428 in complex with NADPH
28% identity, 96% coverage of query (107 bits)
FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
31% identity, 95% coverage of query (107 bits)
1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
31% identity, 95% coverage of query (107 bits)
4nbwA / A6G411 Crystal structure of fabg from plesiocystis pacifica (see paper)
33% identity, 98% coverage of query (107 bits)
7tzpG / A0A332H2K8 Crystal structure of putataive short-chain dehydrogenase/reductase (fabg) from klebsiella pneumoniae subsp. Pneumoniae ntuh-k2044 in complex with nadh (see paper)
32% identity, 96% coverage of query (107 bits)
5jc8D / Q13GE3 Crystal structure of a putative short-chain dehydrogenase/reductase from burkholderia xenovorans
31% identity, 97% coverage of query (107 bits)
1x1tA / Q5KST5 Crystal structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas fragi complexed with NAD+ (see paper)
29% identity, 98% coverage of query (107 bits)
3uf0A / C5BY10 Crystal structure of a putative NAD(p) dependent gluconate 5- dehydrogenase from beutenbergia cavernae(efi target efi-502044) with bound NADP (low occupancy)
34% identity, 96% coverage of query (107 bits)
5h5xC / Q9KYM4 Crystal structure of nadh bound carbonyl reductase from streptomyces coelicolor
32% identity, 96% coverage of query (106 bits)
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