Searching for up to 100 curated homologs for PP_4540 FitnessBrowser__Putida:PP_4540 (270 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
31% identity, 97% coverage of query (114 bits)
6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
32% identity, 97% coverage of query (114 bits)
6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
32% identity, 97% coverage of query (114 bits)
2xuaH / Q13KT2 Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
31% identity, 95% coverage of query (113 bits)
Q13KT2 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Paraburkholderia xenovorans (see 2 papers)
31% identity, 95% coverage of query (113 bits)
Build an alignment for PP_4540 and 5 homologs with ≥ 30% identity
Or download the sequences
bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
26% identity, 96% coverage of query (108 bits)
catD / AAC46435.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 8 papers)
27% identity, 90% coverage of query (105 bits)
TGND_ACIAD / Q6F9F4 (E)-2-((N-methylformamido)methylene)succinate hydrolase; MFMS hydrolase; EC 3.5.1.- from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
29% identity, 92% coverage of query (105 bits)
EstN1 / K0IAM1 pimeloyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) from Nitrososphaera gargensis (strain Ga9.2) (see paper)
29% identity, 93% coverage of query (104 bits)
Q0SH24 3-oxoadipate enol-lactonase (EC 3.1.1.24); 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) from Rhodococcus jostii (see paper)
29% identity, 90% coverage of query (103 bits)
pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
29% identity, 90% coverage of query (103 bits)
5h3hB / K0ACL0 Esterase (eaest) from exiguobacterium antarcticum (see paper)
26% identity, 94% coverage of query (102 bits)
pcaD / Q88N36 subunit of 3-oxoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
Q88N36 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Pseudomonas putida (see paper)
28% identity, 96% coverage of query (100 bits)
pcaD / AAF34270.1 beta-ketoadipate enol-lactone hydrolase from Agrobacterium tumefaciens (see 2 papers)
30% identity, 92% coverage of query (97.4 bits)
AO353_17230 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas fluorescens FW300-N2E3
30% identity, 75% coverage of query (96.3 bits)
6kxhB / A0A0K2AJY3 Alp1u_y247f mutant in complex with fluostatin c (see paper)
27% identity, 93% coverage of query (92.4 bits)
flnE / BAC75995.1 meta cleavage compound hydrolase from Terrabacter sp. DBF63 (see paper)
26% identity, 90% coverage of query (91.7 bits)
pcaD / AAC37150.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 11 papers)
29% identity, 93% coverage of query (90.5 bits)
O73957 carboxylesterase (EC 3.1.1.1) from Sulfolobus acidocaldarius (see paper)
27% identity, 92% coverage of query (88.6 bits)
BPOC_MYCTU / P9WNH1 Putative non-heme bromoperoxidase BpoC from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
28% identity, 93% coverage of query (86.7 bits)
4uhfA / A0A0M3KKY6 Structural studies of a thermophilic esterase from thermogutta terrifontis (l37a mutant with butyrate bound) (see paper)
28% identity, 94% coverage of query (84.7 bits)
3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase
27% identity, 94% coverage of query (84.0 bits)
3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase
27% identity, 94% coverage of query (84.0 bits)
ESTE_PSEFL / P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 8 papers)
GI|951089 arylesterase; EC 1.-.-.-; EC 3.1.1.2 from Pseudomonas fluorescens (see 3 papers)
AAB60168.1 esterase from Pseudomonas fluorescens (see 2 papers)
27% identity, 94% coverage of query (83.6 bits)
3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog
27% identity, 94% coverage of query (83.6 bits)
4uheA Structural studies of a thermophilic esterase from thermogutta terrifontis (malate bound)
28% identity, 91% coverage of query (83.2 bits)
8pi1B / P22862 Bicyclic incypro pseudomonas fluorescens esterase (see paper)
27% identity, 96% coverage of query (82.8 bits)
4uhdA Structural studies of a thermophilic esterase from thermogutta terrifontis (acetate bound)
28% identity, 91% coverage of query (82.8 bits)
Q84II3 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Janthinobacterium sp. J3 (see paper)
26% identity, 93% coverage of query (81.6 bits)
hbpD / O06648 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoate hydrolase [multifunctional] (EC 3.7.1.8) from Pseudomonas nitroreducens (see 2 papers)
27% identity, 91% coverage of query (81.3 bits)
carC / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase monomer (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
CARC_PSERE / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid hydrolase; HOPDA; EC 3.7.1.13 from Pseudomonas resinovorans (see 3 papers)
Q9AQM4 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
carC / BAC41548.1 meta cleavage compound hydrolase from Pseudomonas resinovorans (see 9 papers)
26% identity, 93% coverage of query (80.9 bits)
catD / BAA75208.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see paper)
catD / BAC82535.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see 3 papers)
27% identity, 87% coverage of query (80.5 bits)
hppC / AAB81313.1 2-hydroxy-6-ketonona-2,4-dienoate hydrolase from Rhodococcus globerulus (see paper)
28% identity, 96% coverage of query (80.1 bits)
P96965 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas fluorescens (see 2 papers)
cumD / BAA12150.1 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase from Pseudomonas fluorescens (see paper)
23% identity, 95% coverage of query (80.1 bits)
Q8KT44 carboxylesterase (EC 3.1.1.1) from Lacticaseibacillus casei (see paper)
23% identity, 94% coverage of query (79.0 bits)
1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
23% identity, 95% coverage of query (79.0 bits)
4lxhA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 3- cl hopda (see paper)
24% identity, 95% coverage of query (78.6 bits)
4lyeA Crystal structure of the s105a mutant of a c-c hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with substrate hopda
24% identity, 95% coverage of query (78.6 bits)
4lxiA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 5, 8-dif hopda
24% identity, 95% coverage of query (78.6 bits)
cpoL / PDB|1A88_A non-heme chloroperoxidase; EC 1.11.1.10 from Streptomyces lividans (see 2 papers)
cpoL / AAA18642.1 chloroperoxidase from Streptomyces lividans (see paper)
28% identity, 93% coverage of query (76.6 bits)
cpoF / PDB|1A8S non-heme chloroperoxidase; EC 1.11.1.10 from Pseudomonas fluorescens (see 2 papers)
26% identity, 94% coverage of query (76.3 bits)
1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
23% identity, 94% coverage of query (76.3 bits)
1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
23% identity, 94% coverage of query (76.3 bits)
1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
23% identity, 94% coverage of query (76.3 bits)
1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
23% identity, 94% coverage of query (76.3 bits)
1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
23% identity, 94% coverage of query (76.3 bits)
2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
23% identity, 94% coverage of query (76.3 bits)
bphD / BAM76235.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Janibacter sp. TYM3221 (see paper)
25% identity, 93% coverage of query (75.5 bits)
7c4dA / A0A2S1GUX0 Marine microorganism esterase (see paper)
25% identity, 91% coverage of query (75.1 bits)
5akkA Ligand complex structure of soluble epoxide hydrolase
22% identity, 91% coverage of query (74.7 bits)
7p4kA Soluble epoxide hydrolase in complex with fl217
23% identity, 91% coverage of query (74.7 bits)
nahN / BAE92169.1 2-hydroxymuconic semialdehyde hydrolase NahN from Pseudomonas putida (see 2 papers)
27% identity, 91% coverage of query (74.3 bits)
MhpC / b0349 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpC / P77044 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (strain K12) (see 10 papers)
MHPC_ECOLI / P77044 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; EC 3.7.1.14 from Escherichia coli (strain K12) (see 4 papers)
P77044 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (see 4 papers)
27% identity, 94% coverage of query (74.3 bits)
5aljA / P34913 Ligand complex structure of soluble epoxide hydrolase (see paper)
23% identity, 91% coverage of query (73.9 bits)
thcF / AAC45285.1 chloroperoxidase from Rhodococcus erythropolis (see 2 papers)
27% identity, 94% coverage of query (73.6 bits)
A0A0H2WW38 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20) from Staphylococcus aureus (see paper)
24% identity, 91% coverage of query (72.4 bits)
5alvA Ligand complex structure of soluble epoxide hydrolase
23% identity, 91% coverage of query (72.4 bits)
5jz9A / P9WNH5 Crystal structure of hsad bound to 3,5-dichloro-4- hydroxybenzenesulphonic acid (see paper)
29% identity, 93% coverage of query (72.0 bits)
hsaD / P9WNH5 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase monomer (EC 3.7.1.17) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
HSAD_MYCTU / P9WNH5 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase; 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; Meta-cleavage product hydrolase; MCP hydrolase; EC 3.7.1.17; EC 3.7.1.8 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WNH5 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Mycobacterium tuberculosis (see paper)
29% identity, 93% coverage of query (72.0 bits)
C2F9L5 prolyl aminopeptidase (EC 3.4.11.5) from Lacticaseibacillus paracasei subsp. paracasei (see paper)
29% identity, 89% coverage of query (72.0 bits)
7zm4A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclipostin-like inhibitor cyc31
29% identity, 93% coverage of query (72.0 bits)
7zm3A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclipostin-like inhibitor cyc17
29% identity, 93% coverage of query (72.0 bits)
7zm2A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclophostin-like inhibitor cyc8b
29% identity, 93% coverage of query (72.0 bits)
7zm1A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclophostin-like inhibitor cyc7b
29% identity, 93% coverage of query (72.0 bits)
5jzsB Hsad bound to 3,5-dichloro-4-hydroxybenzoic acid
29% identity, 93% coverage of query (72.0 bits)
5am2A Ligand complex structure of soluble epoxide hydrolase
23% identity, 91% coverage of query (72.0 bits)
6yl4A Soluble epoxide hydrolase in complex with 3-((r)-3-(1-hydroxyureido) but-1-yn-1-yl)-n-((s)-3-phenyl-3-(4-trifluoromethoxy)phenyl)propyl) benzamide
23% identity, 91% coverage of query (72.0 bits)
6hgxA Soluble epoxide hydrolase in complex with 1-(4-((4-(tert-butyl) morpholin-2-yl)methoxy)phenyl)-3-cyclohexylurea
23% identity, 91% coverage of query (72.0 bits)
6hgwA Soluble epoxide hydrolase in complex with 2-(4-fluorophenyl)-n-(4- phenoxybenzyl)ethanamine
23% identity, 91% coverage of query (72.0 bits)
6hgvA Soluble epoxide hydrolase in complex with talinolol
23% identity, 91% coverage of query (72.0 bits)
6fr2A Soluble epoxide hydrolase in complex with lk864
23% identity, 91% coverage of query (72.0 bits)
3antA Human soluble epoxide hydrolase in complex with a synthetic inhibitor
23% identity, 91% coverage of query (72.0 bits)
3ansA Human soluble epoxide hydrolase in complex with a synthetic inhibitor
23% identity, 91% coverage of query (72.0 bits)
6i5gA X-ray structure of human soluble epoxide hydrolasE C-terminal domain (hseh ctd)in complex with 15d-pgj2
23% identity, 91% coverage of query (72.0 bits)
4x6yA Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative
23% identity, 91% coverage of query (72.0 bits)
4x6xA Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative
23% identity, 91% coverage of query (72.0 bits)
4c4zA Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with a8
23% identity, 91% coverage of query (72.0 bits)
bphD / BAA25612.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Rhodococcus erythropolis (see paper)
27% identity, 91% coverage of query (71.6 bits)
7ebaA Co-crystal of kurarinone with seh
23% identity, 91% coverage of query (71.6 bits)
8qmzA Soluble epoxide hydrolase in complex with rk4
23% identity, 91% coverage of query (71.6 bits)
8qn0A Soluble epoxide hydrolase in complex with rk3
23% identity, 91% coverage of query (71.6 bits)
3pdcA Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor
23% identity, 91% coverage of query (71.6 bits)
5jzbA Crystal structure of hsad bound to 3,5-dichlorobenzene sulphonamide
29% identity, 92% coverage of query (71.6 bits)
4jncA Soluble epoxide hydrolase complexed with a carboxamide inhibitor
23% identity, 91% coverage of query (71.6 bits)
4c4yA Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with a4
23% identity, 91% coverage of query (71.6 bits)
4c4xA Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with c9
23% identity, 91% coverage of query (71.6 bits)
PIP_HEYCO / P46541 Proline iminopeptidase; PIP; Prolyl aminopeptidase; PAP; EC 3.4.11.5 from Heyndrickxia coagulans (Weizmannia coagulans) (see 3 papers)
pip / GB|BAA01792.1 prolyl aminopeptidase; EC 3.4.11.5 from Bacillus coagulans (see paper)
25% identity, 91% coverage of query (71.2 bits)
tesD / Q83VZ6 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase (EC 3.7.1.17) from Comamonas testosteroni (see 3 papers)
22% identity, 91% coverage of query (71.2 bits)
A3JB27 haloalkane dehalogenase (EC 3.8.1.5) from Marinobacter sp. (see paper)
25% identity, 93% coverage of query (71.2 bits)
RutD / b1009 putative aminoacrylate hydrolase RutD from Escherichia coli K-12 substr. MG1655 (see 2 papers)
RUTD_ECOLI / P75895 Putative carbamate hydrolase RutD; Aminohydrolase; EC 3.5.1.- from Escherichia coli (strain K12) (see 5 papers)
28% identity, 87% coverage of query (70.9 bits)
7a7gA Soluble epoxide hydrolase in complex with tk90
23% identity, 91% coverage of query (70.9 bits)
3otqA Soluble epoxide hydrolase in complex with pyrazole antagonist
22% identity, 91% coverage of query (70.9 bits)
3kooA Crystal structure of soluble epoxide hydrolase
22% identity, 91% coverage of query (70.9 bits)
3i28A Crystal structure of soluble epoxide hydrolase
22% identity, 91% coverage of query (70.9 bits)
3i1yA Crystal structure of soluble epoxide hydrolase
22% identity, 91% coverage of query (70.9 bits)
6aumA Crystal structure of human soluble epoxide hydrolase complexed with trans-4-[4-(3-trifluoromethoxyphenyl-l-ureido)-cyclohexyloxy]-benzoic acid.
22% identity, 91% coverage of query (70.9 bits)
5aibA Ligand complex structure of soluble epoxide hydrolase
22% identity, 91% coverage of query (70.9 bits)
5ai6A Ligand complex structure of soluble epoxide hydrolase
22% identity, 91% coverage of query (70.9 bits)
1zd5A Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-heptanoic acid complex
22% identity, 91% coverage of query (70.9 bits)
1zd4A Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-hexanoic acid complex
22% identity, 91% coverage of query (70.9 bits)
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Lawrence Berkeley National Laboratory