Sites on a Tree

 

Searching for up to 100 curated homologs for PP_4619 FitnessBrowser__Putida:PP_4619 (210 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Pf6N2E2_5292 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E2
    77% identity, 99% coverage of query (326 bits)

AO356_16835 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2C3
    77% identity, 99% coverage of query (324 bits)

AO353_15560 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E3
    74% identity, 99% coverage of query (317 bits)

2v6kA / O86043 Structure of maleyl pyruvate isomerase, a bacterial glutathione-s- transferase in zeta class, in complex with substrate analogue dicarboxyethyl glutathione (see paper)
    52% identity, 99% coverage of query (208 bits)

nagL / O86043 glutathion-dependent maleylpyruvate isomerase (EC 5.2.1.4) from Ralstonia sp. (see paper)
NAGL_RALSP / O86043 Maleylpyruvate isomerase; MPI; Naphthalene degradation protein L; EC 5.2.1.4 from Ralstonia sp. (see 2 papers)
    52% identity, 99% coverage of query (208 bits)

2jl4A Holo structure of maleyl pyruvate isomerase, a bacterial glutathione- s-transferase in zeta class
    52% identity, 99% coverage of query (208 bits)

Ac3H11_2306 Maleylacetoacetate isomerase (EC 5.2.1.2) from Acidovorax sp. GW101-3H11
    47% identity, 98% coverage of query (197 bits)

Psest_3511 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas stutzeri RCH2
    50% identity, 99% coverage of query (191 bits)

SO1671 Maleylacetoacetate isomerase (EC 5.2.1.2) from Shewanella oneidensis MR-1
    48% identity, 99% coverage of query (191 bits)

Q5K5T6 glutathione transferase subunit (EC 2.5.1.18) from Escherichia coli (see 8 papers)
    46% identity, 99% coverage of query (179 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    45% identity, 99% coverage of query (172 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    45% identity, 99% coverage of query (172 bits)

MAAI2_DROME / Q9VHD2 Probable maleylacetoacetate isomerase 2; MAAI 2; Glutathione S-transferase zeta 2; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    42% identity, 99% coverage of query (171 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    43% identity, 99% coverage of query (167 bits)

MAAI_RAT / P57113 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Rattus norvegicus (Rat) (see paper)
    43% identity, 99% coverage of query (167 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    43% identity, 99% coverage of query (166 bits)

4kdyA / B8J605 Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound gsh in the active site
    45% identity, 99% coverage of query (161 bits)

MAAI1_DROME / Q9VHD3 Probable maleylacetoacetate isomerase 1; MAAI 1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    41% identity, 99% coverage of query (161 bits)

4kaeA Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound dicarboxyethyl glutathione and citrate in the active site
    45% identity, 99% coverage of query (161 bits)

GSTZ1_ARATH / Q9ZVQ3 Glutathione S-transferase Z1; AtGSTZ1; GST class-zeta member 1; Glutathione S-transferase 18; Maleylacetone isomerase; MAI; EC 2.5.1.18; EC 5.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    40% identity, 100% coverage of query (150 bits)

MAIA_ASPFU / Q4WHT7 Maleylacetoacetate isomerase maiA; EC 5.2.1.2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 3 papers)
    40% identity, 100% coverage of query (146 bits)

maiA / O43123 maleylacetoacetate isomerase (EC 5.2.1.2) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (see paper)
MAAI_EMENI / O43123 Maleylacetoacetate isomerase; MAAI; EC 5.2.1.2 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
O43123 maleylacetoacetate isomerase (EC 5.2.1.2) from Aspergillus nidulans (see paper)
GI|2832725 maleylacetoacetate isomerase; EC 5.2.1.2 from Emericella nidulans (see paper)
maiA / CAA05041.1 maleylacetoacetate isomerase from Aspergillus nidulans (see paper)
maiA / CAA05044.1 maleylacetoacetate isomerase from Aspergillus nidulans (see paper)
    39% identity, 100% coverage of query (144 bits)

3n5oA / D2YW48 Crystal structure of putative glutathione transferase from coccidioides immitis bound to glutathione (see paper)
    39% identity, 99% coverage of query (139 bits)

D2YW48 Probable glutathione S-transferase; EC 2.5.1.18 from Coccidioides immitis (strain RS) (Valley fever fungus)
    39% identity, 99% coverage of query (139 bits)

4pxoA / C5ATQ9 Crystal structure of maleylacetoacetate isomerase from methylobacteriu extorquens am1 with bound malonate and gsh (target efi-507068)
    37% identity, 100% coverage of query (122 bits)

O04437 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    36% identity, 99% coverage of query (114 bits)

Build an alignment

Build an alignment for PP_4619 and 26 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

3qawA / B9VX79 Crystal structure of a glutathione-s-transferase from antarctic clam laternula elliptica in a complex with glutathione (see paper)
    27% identity, 99% coverage of query (74.7 bits)

3uarA / Q60CN1 Crystal structure of glutathione transferase (target efi-501774) from methylococcus capsulatus str. Bath with gsh bound
    31% identity, 97% coverage of query (70.9 bits)

1f2eA / O33705 Structure of sphingomonad, glutathione s-transferase complexed with glutathione
GST / AAC46031.1 glutathione S-transferase from Sphingomonas paucimobilis (see paper)
    28% identity, 89% coverage of query (67.8 bits)

XYLK / AAC44159.1 glutathione S-transferase from Cycloclasticus oligotrophus (see paper)
    28% identity, 95% coverage of query (67.0 bits)

6m1tA / O30347 Bacterial beta class sphingomonas chungbukensis glutathione s- transferase
    27% identity, 89% coverage of query (65.9 bits)

2gdrA / Q59721 Crystal structure of a bacterial glutathione transferase (see paper)
    28% identity, 87% coverage of query (64.7 bits)

A0A4Y5R0C1 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    31% identity, 84% coverage of query (64.7 bits)

2dsaA Ternary complex of bphk, a bacterial gst
    28% identity, 87% coverage of query (64.7 bits)

4gf0A / A3STM0 Crystal structure of glutahtione transferase homolog from sulfitobacter, target efi-501084, with bound glutathione
    27% identity, 76% coverage of query (64.3 bits)

Q59721 4-chlorobenzoate dehalogenase (EC 3.8.1.6) from Burkholderia sp. (see paper)
bphK / CAA54033.1 glutathione S-transferase from Paraburkholderia xenovorans LB400 (see paper)
    28% identity, 87% coverage of query (64.3 bits)

desD / Q2G4C2 4-carboxy-2-hydroxyhexa-2,4-dienedioate cis-trans isomerase from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199) (see paper)
    29% identity, 94% coverage of query (64.3 bits)

3m3mA / Q4K8I0 Crystal structure of glutathione s-transferase from pseudomonas fluorescens [pf-5]
    25% identity, 92% coverage of query (64.3 bits)

D2WL48 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    26% identity, 86% coverage of query (62.0 bits)

GSTFA_ARATH / P42761 Glutathione S-transferase F10; AtGSTF10; AtGSTF4; GST class-phi member 10; Protein EARLY RESPONSE TO DEHYDRATION 13; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    30% identity, 74% coverage of query (62.0 bits)

Pog / b3229 stringent starvation protein A from Escherichia coli K-12 substr. MG1655 (see 8 papers)
TC 1.A.12.3.1 / P0ACA3 The bacterial CLIC homologue, stringent starvation protein A, SspA (212 aas; 0 TMSs) [N-terminal Trx domain; C-terminal glutathione S-transferase (GST) domain] from Escherichia coli (strain K12) (see 5 papers)
sspA stringent starvation protein A from Escherichia coli K12 (see 5 papers)
    27% identity, 84% coverage of query (61.6 bits)

GSTF3_MAIZE / P04907 Glutathione S-transferase 3; GST class-phi member 3; GST-III; EC 2.5.1.18 from Zea mays (Maize) (see 2 papers)
    32% identity, 81% coverage of query (61.2 bits)

3touA / Q8XVV6 Crystal structure of glutathione transferase (target efi-501058) from ralstonia solanacearum gmi1000 with gsh bound
    28% identity, 77% coverage of query (61.2 bits)

SSPA_COXBU / Q83AY0 Stringent starvation protein A homolog from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see paper)
    27% identity, 80% coverage of query (61.2 bits)

GSTF8 / Q96266 glutathione S-transferase F8 monomer (EC 2.5.1.18) from Arabidopsis thaliana (see 6 papers)
GSTF8_ARATH / Q96266 Glutathione S-transferase F8, chloroplastic; AtGSTF8; AtGSTF5; GST class-phi member 8; Glutathione S-transferase 6; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    26% identity, 90% coverage of query (60.5 bits)

Q8RW03 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    32% identity, 78% coverage of query (60.5 bits)

gst7 / CAB38121.1 GST7 protein from Zea mays (see paper)
    28% identity, 89% coverage of query (60.1 bits)

Q8RW04 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    32% identity, 78% coverage of query (59.3 bits)

4zb8A / A0A0R4I981 Crystal structure of the glutathione transferase ure2p6 from phanerochaete chrysosporium in complex with oxidized glutathione. (see paper)
    25% identity, 93% coverage of query (58.9 bits)

4zbdA Crystal structure of the glutathione transferase ure2p6 from phanerochaete chrysosporium in complex with glutathione reduced by x- ray irradiation at 100k
    25% identity, 93% coverage of query (58.9 bits)

5agyA / I1MJ34 Crystal structure of a tau class gst mutant from glycine (see paper)
    27% identity, 96% coverage of query (58.5 bits)

A0A4Y5QZX9 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 80% coverage of query (58.2 bits)

O49235 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    27% identity, 96% coverage of query (58.2 bits)

Q8RW02 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    31% identity, 78% coverage of query (58.2 bits)

4topA Glycine max glutathione transferase
    27% identity, 96% coverage of query (58.2 bits)

GSTF1_TOBAC / P30109 Glutathione S-transferase PARB; GST class-phi; EC 2.5.1.18 from Nicotiana tabacum (Common tobacco) (see paper)
    26% identity, 90% coverage of query (57.8 bits)

GSTF2_TOBAC / P46440 Glutathione S-transferase APIC; GST class-phi; EC 2.5.1.18 from Nicotiana tabacum (Common tobacco)
    26% identity, 90% coverage of query (57.8 bits)

4qq7A / B4E6Q3 Crystal structure of putative stringent starvation protein a from burkholderia cenocepacia with bound glutathione
    25% identity, 95% coverage of query (57.4 bits)

GSTD7_DROME / Q9VG93 Glutathione S-transferase D7; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    25% identity, 88% coverage of query (57.0 bits)

3ublA / Q8F2Y8 Crystal structure of glutathione transferase (target efi-501770) from leptospira interrogans with gsh bound
    25% identity, 72% coverage of query (57.0 bits)

4g9hA / Q8D0L3 Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione
    24% identity, 97% coverage of query (57.0 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    25% identity, 97% coverage of query (56.6 bits)

ndmE / R9TPE4 glutathione-S-transferase NdmE (EC 1.14.13.128) from Pseudomonas putida (see paper)
    25% identity, 93% coverage of query (56.6 bits)

Q9FQE8 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    26% identity, 96% coverage of query (56.2 bits)

7dw4A / A0A4Y5R032 Crystal structure of a glutathione s-transferase mutant sbgstu6(i55t) from salix babylonica in complex with glutathione
    28% identity, 91% coverage of query (56.2 bits)

4chsA Crystal structure of a tau class glutathione transferase 10 from glycine max
    26% identity, 96% coverage of query (56.2 bits)

4ivfF / A5E437 Crystal structure of glutathione transferase homolog from lodderomyces elongisporus, target efi-501753, with two gsh per subunit
    22% identity, 81% coverage of query (55.8 bits)

4zb6D / A0A0R4I980 Crystal structure of glutathione transferase ure2p4 from phanerochaete chrysosporium in complex with oxidized glutathione. (see paper)
    25% identity, 93% coverage of query (54.7 bits)

7dweA / A0A4Y5R087 Crystal structure of a glutathione s-transferase sbgstu7 from salix babylonica in complex with glutathione
    27% identity, 77% coverage of query (54.3 bits)

8ai8A / Q55139 Crystal structure of glutathione transferase chi 1 from synechocystis sp. Pcc 6803 in complex with glutathione (see paper)
    29% identity, 83% coverage of query (53.5 bits)

7pkaA Synechocystis sp. Pcc6803 glutathione transferase chi 1, gsoh bound
    29% identity, 83% coverage of query (53.5 bits)

4isdA / C5A7Z5 Crystal structure of glutathione transferase homolog from burkholderia gl bgr1, target efi-501803, with bound glutathione
    32% identity, 70% coverage of query (53.1 bits)

4hz2B / A7ILT8 Crystal structure of glutathione s-transferase xaut_3756 (target efi- 507152) from xanthobacter autotrophicus py2
    27% identity, 90% coverage of query (52.8 bits)

5j4uA / B9I0G5 Crystal structure of a glutathione s-transferase ptgstu30 from populus trichocarpa in complex with gsh
    25% identity, 94% coverage of query (52.8 bits)

YibF / b3592 glutathione transferase-like protein YibF from Escherichia coli K-12 substr. MG1655 (see 4 papers)
3r2qA / P0ACA1 Crystal structure analysis of yibf from e. Coli
yibF / RF|NP_418049 uncharacterized GST-like protein yibF from Escherichia coli K12 (see 2 papers)
    31% identity, 77% coverage of query (52.0 bits)

P0ACA1 Uncharacterized GST-like protein YibF from Escherichia coli (strain K12)
    31% identity, 77% coverage of query (52.0 bits)

8ax1A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with hydroxy-tetranitro-nitrosyl-ruthenate
    29% identity, 80% coverage of query (51.6 bits)

6f51A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-phenylacetophenone
    29% identity, 80% coverage of query (51.6 bits)

8ax0A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with sodium nitroprusside
    29% identity, 80% coverage of query (51.6 bits)

8awzA / A0A384E145 Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with dinitrosyl glutathionyl iron complex (dngic) (see paper)
    29% identity, 80% coverage of query (51.6 bits)

6hpeA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with the glutathione adduct of phenethyl- isothiocyanate
    29% identity, 80% coverage of query (51.6 bits)

6f6aA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with dihydrowogonin from wild-cherry extract
    29% identity, 80% coverage of query (51.6 bits)

6f69A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 2,3,4-trihydroxybenzophenone
    29% identity, 80% coverage of query (51.6 bits)

6f68A Crystal structure glutathione transferase omega 3s from trametes versicolor in complex with 2,4,4'-trihydroxybenzophenone
    29% identity, 80% coverage of query (51.6 bits)

6f67A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 3,4-dihydroxybenzophenone
    29% identity, 80% coverage of query (51.6 bits)

6f66A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 2,4-dihydroxybenzophenone
    29% identity, 80% coverage of query (51.6 bits)

6f4kA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with hexyl-glutathione
    29% identity, 80% coverage of query (51.6 bits)

6f4fA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-s-dinitrobenzene
    29% identity, 80% coverage of query (51.6 bits)

7zvpA Crystal structure of poplar glutathione transferase u19 in complex with glutathione
    27% identity, 77% coverage of query (51.6 bits)

3m0fA / Q4KDJ6 Crystal structure of glutathione s transferase in complex with glutathione from pseudomonas fluorescens
    28% identity, 89% coverage of query (50.1 bits)

GST_BRUAN / P81065 Glutathione S-transferase; EC 2.5.1.18 from Brucella anthropi (Ochrobactrum anthropi) (see paper)
P81065 glutathione transferase (EC 2.5.1.18) from Brucella anthropi (see paper)
2ntoA / P81065 Structure of the glutathione transferase from ochrobactrum anthropi in complex with glutathione (see paper)
    28% identity, 95% coverage of query (49.7 bits)

5evoA / U5XYA0 Structure of dehydroascrobate reductase from pennisetum americanum in complex with two non-native ligands, acetate in the g-site and glycerol in the h-site (see paper)
    23% identity, 92% coverage of query (49.3 bits)

4g10A / Q9WXJ9 Ligg from sphingobium sp. Syk-6 is related to the glutathione transferase omega class (see paper)
    27% identity, 88% coverage of query (48.9 bits)

4yavA Crystal structure of ligg in complex with b-glutathionyl- acetoveratrone (gs-av) from sphingobium sp. Strain syk-6
    27% identity, 88% coverage of query (48.9 bits)

6wegD Structure of ft (mgla-sspa)-ppgpp-pigr peptide complex
    26% identity, 83% coverage of query (48.5 bits)

6wmtS F. Tularensis rnaps70-(mgla-sspa)-ppgpp-pigr-igla DNA complex (see paper)
    26% identity, 83% coverage of query (48.5 bits)

1jzrA / P23202 Ure2p in complex with glutathione (see paper)
    23% identity, 94% coverage of query (48.1 bits)

4mpgB / P0CG30 Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target efi-507257
    28% identity, 99% coverage of query (48.1 bits)

5d9xA Dehydroascorbate reductase complexed with gsh
    24% identity, 76% coverage of query (48.1 bits)

5d9wA Dehydroascorbate reductase (osdhar) complexed with asa
    24% identity, 76% coverage of query (48.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory