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Searching for up to 100 curated homologs for PP_4757 FitnessBrowser__Putida:PP_4757 (448 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

gudD / P42206 D-glucarate dehydratase subunit (EC 4.2.1.40) from Pseudomonas putida (see paper)
GUDD_PSEPU / P42206 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    79% identity, 100% coverage of query (731 bits)

YgcX / b2787 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
gudD / P0AES2 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli (strain K12) (see 5 papers)
GUDD_ECOLI / P0AES2 Glucarate dehydratase; GDH; GlucD; D-glucarate dehydratase; EC 4.2.1.40 from Escherichia coli (strain K12) (see 3 papers)
gudD / RF|NP_417267 glucarate dehydratase; EC 4.2.1.40 from Escherichia coli K12 (see 8 papers)
    73% identity, 98% coverage of query (697 bits)

1ec9D / P0AES2 E. Coli glucarate dehydratase bound to xylarohydroxamate (see paper)
    73% identity, 98% coverage of query (697 bits)

1ec8A E. Coli glucarate dehydratase bound to product 2,3-dihydroxy-5-oxo- hexanedioate
    73% identity, 98% coverage of query (697 bits)

1ecqA E. Coli glucarate dehydratase bound to 4-deoxyglucarate
    73% identity, 98% coverage of query (697 bits)

1jctA Glucarate dehydratase, n341l mutant orthorhombic form
    72% identity, 98% coverage of query (693 bits)

gudD / Q6FFQ2 D-glucarate dehydratase subunit (EC 4.2.1.40) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
GUDD_ACIAD / Q6FFQ2 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ2 glucarate dehydratase (EC 4.2.1.40) from Acinetobacter baylyi (see paper)
    70% identity, 98% coverage of query (667 bits)

3p0wB / B2UIZ1 Crystal structure of d-glucarate dehydratase from ralstonia solanacearum complexed with mg and d-glucarate
    68% identity, 98% coverage of query (593 bits)

3nxlC / Q39KL8 Crystal structure of glucarate dehydratase from burkholderia cepacia complexed with magnesium
    68% identity, 98% coverage of query (580 bits)

GudX / b2788 glucarate dehydratase-related protein from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GUDX_ECOLI / Q46915 Glucarate dehydratase-related protein; GDH-RP; GlucDRP; EC 4.2.1.- from Escherichia coli (strain K12) (see paper)
gudX / RF|NP_417268 glucarate dehydratase-related protein from Escherichia coli K12
    64% identity, 98% coverage of query (577 bits)

3nfuA / Q1QUN0 Crystal structure of probable glucarate dehydratase from chromohalobacter salexigens dsm 3043 complexed with magnesium
    61% identity, 98% coverage of query (561 bits)

3n6hB / A6VQF6 Crystal structure of mandelate racemase/muconate lactonizing protein from actinobacillus succinogenes 130z complexed with magnesium/sulfate
    60% identity, 98% coverage of query (541 bits)

3pfrA Crystal structure of d-glucarate dehydratase related protein from actinobacillus succinogenes complexed with d-glucarate
    59% identity, 98% coverage of query (540 bits)

4it1D / Q3KB33 Crystal structure of enolase pfl01_3283 (target efi-502286) from pseudomonas fluorescens pf0-1 with bound magnesium, potassium and tartrate
    37% identity, 95% coverage of query (232 bits)

3va8A Crystal structure of enolase fg03645.1 (target efi-502278) from gibberella zeae ph-1 complexed with magnesium, formate and sulfate
    34% identity, 97% coverage of query (226 bits)

3vc6A / D6Y7Y6 Crystal structure of enolase tbis_1083(target efi-502310) from thermobispora bispora dsm 43833 complexed with magnesium and formate
    36% identity, 96% coverage of query (225 bits)

Build an alignment

Build an alignment for PP_4757 and 16 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

D4GYD4 gluconate dehydratase (EC 4.2.1.39) from Haloferax volcanii (see paper)
    25% identity, 83% coverage of query (73.6 bits)

BPHYT_RS16405 galactonate dehydratase [EC: 4.2.1.6] from Burkholderia phytofirmans PsJN
    26% identity, 71% coverage of query (55.5 bits)

2gghC / Q9RYA6 The mutant a68c-d72c-nlq of deinococcus radiodurans nacylamino acid racemase (see paper)
    26% identity, 72% coverage of query (55.5 bits)

3i6tB / Q28SI7 Crystal structure of muconate cycloisomerase from jannaschia sp.
    27% identity, 83% coverage of query (54.3 bits)

3ugvF / A8TYI5 Crystal structure of an enolase from alpha pretobacterium bal199 (efi target efi-501650) with bound mg
    24% identity, 77% coverage of query (53.9 bits)

catB / BAE46388.1 cis,cis-muconate cycloisomerase from Rhodococcus sp. AN-22 (see paper)
    24% identity, 82% coverage of query (47.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory