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Searching for up to 100 curated homologs for PP_5257 FitnessBrowser__Putida:PP_5257 (432 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

Removed hits that are identical to the query, leaving 22

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YcjA / b1301 γ-glutamylputrescine oxidase from Escherichia coli K-12 substr. MG1655 (see 6 papers)
puuB / P37906 γ-glutamylputrescine oxidase from Escherichia coli (strain K12) (see 4 papers)
PUUB_ECOLI / P37906 Gamma-glutamylputrescine oxidoreductase; Gamma-Glu-Put oxidase; Gamma-glutamylputrescine oxidase; EC 1.4.3.- from Escherichia coli (strain K12) (see paper)
puuB / BAD88709.1 gamma-glutamylputrescine oxidase from Escherichia coli K-12 (see paper)
    32% identity, 90% coverage of query (145 bits)

Build an alignment

Build an alignment for PP_5257 and 1 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

AO356_21495 gamma-glutamylputrescine oxidase (EC 1.4.3.-) from Pseudomonas fluorescens FW300-N2C3
    29% identity, 93% coverage of query (138 bits)

Pf6N2E2_80 gamma-glutamylputrescine oxidase (EC 1.4.3.-) from Pseudomonas fluorescens FW300-N2E2
    29% identity, 88% coverage of query (126 bits)

Q6RH53 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus pantotrophus (see paper)
    27% identity, 92% coverage of query (95.1 bits)

Q1XEP4 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus versutus (see paper)
    28% identity, 91% coverage of query (93.6 bits)

Q6RH61 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus denitrificans (see paper)
    27% identity, 92% coverage of query (81.3 bits)

Q6RH44 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus pantotrophus (see paper)
    27% identity, 91% coverage of query (72.4 bits)

mabO / Q8GAI3 4-methylaminobutyrate oxidase (demethylating) (EC 1.5.3.19) from Paenarthrobacter nicotinovorans (see 2 papers)
MABO1_PAENI / Q8GAI3 4-methylaminobutanoate oxidase (formaldehyde-forming); MABO; Demethylating gamma-N-methylaminobutyrate oxidase; Gamma-N-methylaminobutyrate oxidase 1; EC 1.5.3.19 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see 2 papers)
    24% identity, 82% coverage of query (66.2 bits)

amaD / Q88GX1 D-lysine oxidase (EC 1.4.3.3) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
    25% identity, 84% coverage of query (66.2 bits)

5i39A / Q9LCB2 High resolution structure of l-amino acid deaminase from proteus vulgaris with the deletion of the specific insertion sequence (see paper)
    23% identity, 86% coverage of query (65.1 bits)

Q8U022 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus furiosus (see paper)
    22% identity, 80% coverage of query (63.9 bits)

DMGDH / Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 6 papers)
M2GD_HUMAN / Q9UI17 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Homo sapiens (Human) (see 2 papers)
Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 2 papers)
    23% identity, 91% coverage of query (63.5 bits)

Q5JFG2 proline dehydrogenase (EC 1.5.5.2) from Thermococcus kodakarensis (see paper)
    25% identity, 82% coverage of query (62.0 bits)

L7T8Y9 glycine oxidase (EC 1.4.3.19) from Bacillus cereus (see 2 papers)
    25% identity, 82% coverage of query (60.8 bits)

7cyxA / Q81HQ7 Crystal strcuture of glycine oxidase from bacillus cereus atcc 14579 (see paper)
    25% identity, 82% coverage of query (60.8 bits)

Q9DBT9 dimethylglycine dehydrogenase (EC 1.5.8.4) from Mus musculus (see paper)
    22% identity, 86% coverage of query (58.5 bits)

nmpC / A0A222FYP8 4-methylaminobutanoate oxidase (EC 1.5.3.21) from Alicycliphilus sp. (see paper)
    24% identity, 88% coverage of query (58.5 bits)

Q76M73 proline dehydrogenase (EC 1.5.5.2) from Thermococcus profundus (see 2 papers)
    25% identity, 82% coverage of query (58.5 bits)

2gagB Heteroteterameric sarcosine: structure of a diflavin metaloenzyme at 1.85 a resolution
    24% identity, 85% coverage of query (56.6 bits)

O59445 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    23% identity, 80% coverage of query (55.8 bits)

SarDH / Q64380 sarcosine dehydrogenase (EC 1.5.8.3) from Rattus norvegicus (see 10 papers)
SARDH_RAT / Q64380 Sarcosine dehydrogenase, mitochondrial; SarDH; EC 1.5.8.3 from Rattus norvegicus (Rat) (see 2 papers)
    22% identity, 84% coverage of query (55.1 bits)

SARDH / Q9UL12 sarcosine dehydrogenase (EC 1.5.8.3) from Homo sapiens (see 5 papers)
SARDH_HUMAN / Q9UL12 Sarcosine dehydrogenase, mitochondrial; SarDH; BPR-2; EC 1.5.8.3 from Homo sapiens (Human) (see 2 papers)
    22% identity, 84% coverage of query (53.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory