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Searching for up to 100 curated homologs for Pf1N1B4_10 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_10 (336 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DHAS2_VIBCH / P23247 Aspartate-semialdehyde dehydrogenase 2; ASA dehydrogenase 2; ASADH 2; Aspartate-beta-semialdehyde dehydrogenase 2; EC 1.2.1.11 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
    42% identity, 100% coverage of query (278 bits)

2r00C / P23247 Crystal structure of aspartate semialdehyde dehydrogenase ii complexed with asa from vibrio cholerae (see paper)
    42% identity, 100% coverage of query (275 bits)

Usg / b2319 putative semialdehyde dehydrogenase Usg from Escherichia coli K-12 substr. MG1655 (see 6 papers)
usg / RF|NP_416822 USG-1 protein from Escherichia coli K12 (see 2 papers)
    41% identity, 100% coverage of query (236 bits)

asd / Q04797 aspartate semialdehyde dehydrogenase subunit (EC 1.2.1.11) from Bacillus subtilis (strain 168) (see paper)
    34% identity, 99% coverage of query (203 bits)

Q04797 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Bacillus subtilis (strain 168)
    34% identity, 99% coverage of query (203 bits)

AT1G14810 / Q8VYI4 aspartate semialdehyde dehydrogenase (EC 1.2.1.11) from Arabidopsis thaliana (see paper)
    34% identity, 97% coverage of query (184 bits)

4r54A Complex crystal structure of sp-aspartate-semialdehyde-dehydrogenase with 3-carboxy-ethyl-phthalic acid
    33% identity, 97% coverage of query (181 bits)

4r41A Complex crystal structure of 4-nitro-2-phosphono-benzoic acid with sp- aspartate-semialdehyde dehydrogenase and nicotinamide-dinucleotide
    33% identity, 97% coverage of query (181 bits)

4r3nA Crystal structure of the ternary complex of sp-asadh with NADP and 1, 2,3-benzenetricarboxylic acid
    33% identity, 97% coverage of query (181 bits)

3q1lA Crystals structure of aspartate beta-semialdehyde dehydrogenase from streptococcus pneumoniae with cysteamine bound covalently to cys 128
    33% identity, 97% coverage of query (181 bits)

3pwsA Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with 2',5'-adenosine diphosphate and d-2- aminoadipate
    33% identity, 97% coverage of query (181 bits)

3pwkA Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with 2',5'-adenosine diphosphate and d-2- aminoadipate
    33% identity, 97% coverage of query (181 bits)

2gz3A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with NADP and aspartate- semialdehyde
    33% identity, 97% coverage of query (181 bits)

2gz2A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with 2',5'-adp
    33% identity, 97% coverage of query (181 bits)

2gz1A Structure of aspartate semialdehyde dehydrogenase (asadh) from streptococcus pneumoniae complexed with NADP
    33% identity, 97% coverage of query (181 bits)

4r51A Crystal complex structure of sp-aspartate-semialdehyde-dehydrogenase with nicotinamide adenine dinucleotide phosphate and phthalic acid
    33% identity, 97% coverage of query (181 bits)

3pylC Crystal structure of aspartate beta-semialdehide dehydrogenase from streptococcus pneumoniae with d-2,3-diaminopropionate (see paper)
    33% identity, 97% coverage of query (180 bits)

4r5hA Crystal structure of sp-aspartate-semialdehyde-dehydrogenase with nicotinamide-adenine-dinucleotide-phosphate and 3-carboxy-propenyl- phthalic acid
    33% identity, 97% coverage of query (180 bits)

4r4jA Crystal structure of complex sp_asadh with 3-carboxypropyl-phthalic acid and nicotinamide adenine dinucleotide phosphate
    33% identity, 97% coverage of query (180 bits)

3pyxB Crystals structure of aspartate beta-semialdehyde dehydrogenase complex with NADP and 2-aminoterephthalate
    33% identity, 97% coverage of query (180 bits)

3q11A Crystals structure of aspartate beta-semialdehyde dehydrogenase from streptococcus pneumoniae with NADP and aspartyl beta- difluorophosphonate
    33% identity, 97% coverage of query (180 bits)

DHAS_MYCTU / P9WNX5 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WNX5 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Mycobacterium tuberculosis (see 5 papers)
    34% identity, 98% coverage of query (167 bits)

3tz6A / P9WNX5 Crystal structure of aspartate semialdehyde dehydrogenase complexed with inhibitor smcs (cys) and phosphate from mycobacterium tuberculosis h37rv (see paper)
    34% identity, 97% coverage of query (163 bits)

Q8KQ27 aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) from Streptomyces clavuligerus (see paper)
    30% identity, 98% coverage of query (124 bits)

Build an alignment

Build an alignment for Pf1N1B4_10 and 24 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

1ys4A / Q57658 Structure of aspartate-semialdehyde dehydrogenase from methanococcus jannaschii (see paper)
    24% identity, 98% coverage of query (54.7 bits)

asd / Q57658 aspartate-semialdehyde dehydrogenase monomer (EC 1.2.1.11) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
DHAS_METJA / Q57658 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    24% identity, 98% coverage of query (54.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory