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Searching for up to 100 curated homologs for Pf1N1B4_1101 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_1101 (483 a.a.)

Found high-coverage hits (≥70%) to 59 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

gatA / O06491 glutamyl-tRNAGln amidotransferase subunit A (EC 6.3.5.7) from Bacillus subtilis (strain 168) (see paper)
GATA_BACSU / O06491 Glutamyl-tRNA(Gln) amidotransferase subunit A; Glu-ADT subunit A; EC 6.3.5.7 from Bacillus subtilis (strain 168) (see 2 papers)
    51% identity, 99% coverage of query (484 bits)

3h0lA / O66610 Structure of tRNA-dependent amidotransferase gatcab from aquifex aeolicus (see paper)
    49% identity, 99% coverage of query (472 bits)

3h0mA Structure of tRNA-dependent amidotransferase gatcab from aquifex aeolicus
    49% identity, 99% coverage of query (472 bits)

P63488 glutaminyl-tRNA synthase (glutamine-hydrolysing) (subunit 2/2) (EC 6.3.5.7) from Staphylococcus aureus (see paper)
2dqnA / P63488 Structure of tRNA-dependent amidotransferase gatcab complexed with asn (see paper)
    49% identity, 96% coverage of query (448 bits)

2f2aA Structure of tRNA-dependent amidotransferase gatcab complexed with gln
    49% identity, 96% coverage of query (448 bits)

gatA / Q9RTA9 glutamyl-tRNAGln amidotransferase subunit A (EC 6.3.5.7; EC 6.3.5.6) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
    52% identity, 95% coverage of query (440 bits)

Q9X0Z9 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Thermotoga maritima (see paper)
    43% identity, 99% coverage of query (404 bits)

3kfuE / Q9LCX3 Crystal structure of the transamidosome (see paper)
    49% identity, 100% coverage of query (396 bits)

GATA_ARATH / Q9LI77 Glutamyl-tRNA(Gln) amidotransferase subunit A, chloroplastic/mitochondrial; Glu-AdT subunit A; EC 6.3.5.7 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    45% identity, 97% coverage of query (390 bits)

GATA_HUMAN / Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Glu-AdT subunit A; Glutaminyl-tRNA synthase-like protein 1; EC 6.3.5.7 from Homo sapiens (Human) (see 3 papers)
Q9H0R6 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Homo sapiens (see paper)
    39% identity, 96% coverage of query (329 bits)

Q9CZN8 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Mus musculus (see paper)
    38% identity, 96% coverage of query (316 bits)

GATA_YEAST / Q03557 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Glu-AdT subunit A; HMG2-induced ER-remodeling protein 2; Loss of respiratory capacity protein 6; EC 6.3.5.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
    35% identity, 84% coverage of query (241 bits)

4n0iA / Q03557 Crystal structure of s. Cerevisiae mitochondrial gatfab in complex with glutamine (see paper)
    35% identity, 83% coverage of query (240 bits)

cahA / BAC15598.1 carbaryl hydrolase from Arthrobacter sp. RC100 (see paper)
    37% identity, 96% coverage of query (221 bits)

pam / GI|19744118 peptide amidase from Stenotrophomonas maltophilia (see paper)
pam / CAC93616.1 peptide amidase from Stenotrophomonas maltophilia (see paper)
    34% identity, 99% coverage of query (198 bits)

1m21A / Q8RJN5 Crystal structure analysis of the peptide amidase pam in complex with the competitive inhibitor chymostatin (see paper)
    35% identity, 97% coverage of query (197 bits)

P95896 amidase (EC 3.5.1.4); nitrilase (EC 3.5.5.1) from Saccharolobus solfataricus (see 3 papers)
    32% identity, 84% coverage of query (195 bits)

amdA / P27765 nicotinamidase (EC 3.5.1.19) from Pseudomonas chlororaphis (see paper)
    34% identity, 86% coverage of query (192 bits)

atzE / Q936X3 1-carboxybiuret hydrolase catalytic subunit (EC 3.5.1.3; EC 3.5.1.131) from Pseudomonas sp. (strain ADP) (see 2 papers)
ATZE_PSESD / Q936X3 1-carboxybiuret hydrolase subunit AtzE; EC 3.5.1.131 from Pseudomonas sp. (strain ADP) (see 2 papers)
Q936X3 1-carboxybiuret hydrolase (EC 3.5.1.131) from Pseudomonas sp. ADP (see paper)
6c6gA / Q936X3 An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme. Inhibitor bound complex. (see paper)
    35% identity, 97% coverage of query (190 bits)

P22984 amidase (EC 3.5.1.4) from Rhodococcus erythropolis (see 2 papers)
Q7DKE4 amidase (EC 3.5.1.4) from Rhodococcus sp. N-771 (see paper)
amdA / AAA62721.1 enantiomer-selective amidase from Brevibacterium sp (see paper)
CAA38009.1 amidase from Rhodococcus sp (see paper)
    33% identity, 84% coverage of query (180 bits)

3a1iA / Q7DKE4 Crystal structure of rhodococcus sp. N-771 amidase complexed with benzamide (see paper)
    33% identity, 84% coverage of query (179 bits)

B1GY01 nitrilase (EC 3.5.5.1) from Rhodococcus erythropolis (see paper)
    33% identity, 84% coverage of query (178 bits)

FAAH_MEDTR / G7ISB0 Fatty acid amide hydrolase; N-acylethanolamine amidohydrolase; EC 3.5.1.- from Medicago truncatula (Barrel medic) (Medicago tribuloides) (see paper)
    33% identity, 86% coverage of query (169 bits)

Build an alignment

Build an alignment for Pf1N1B4_1101 and 23 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

A0A509AHQ9 glutaminyl-tRNA synthase (glutamine-hydrolysing) (subunit 2/2) (EC 6.3.5.7) from Plasmodium berghei (see paper)
    29% identity, 83% coverage of query (169 bits)

CNBH_COMTE / Q38M35 2-amino-5-chloromuconic acid deaminase; 2-aminomuconate deaminase; EC 3.5.99.5 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
    31% identity, 96% coverage of query (167 bits)

FAAH_ARATH / Q7XJJ7 Fatty acid amide hydrolase; AtFAAH; N-acylethanolamine amidohydrolase; EC 3.5.1.99 from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
Q7XJJ7 fatty acid amide hydrolase (EC 3.5.1.99) from Arabidopsis thaliana (see paper)
    30% identity, 88% coverage of query (165 bits)

6diiH / Q7XJJ7 Structure of arabidopsis fatty acid amide hydrolase in complex with methyl linolenyl fluorophosphonate (see paper)
    30% identity, 88% coverage of query (165 bits)

MANHY_PSEPU / Q84DC4 Mandelamide hydrolase; EC 3.5.1.86 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
    31% identity, 97% coverage of query (164 bits)

AAM_RHOER / K9NBS6 Acylamidase; EC 3.5.1.13; EC 3.5.1.14; EC 3.5.1.4 from Rhodococcus erythropolis (Arthrobacter picolinophilus) (see paper)
    28% identity, 99% coverage of query (159 bits)

tms2 / P0A2X0 indoleacetamide hydrolase (EC 3.5.1.4) from Rhizobium radiobacter (see paper)
    31% identity, 95% coverage of query (155 bits)

FAAH_ORYSJ / Q0JFH7 Fatty acid amide hydrolase; N-acylethanolamine amidohydrolase; EC 3.5.1.- from Oryza sativa subsp. japonica (Rice) (see paper)
    30% identity, 93% coverage of query (151 bits)

iaaH / GB|AAA17679.1 indoleacetamide hydrolase; EC 3.5.1.- from Pseudomonas syringae pv. syringae (see paper)
    31% identity, 95% coverage of query (146 bits)

C3UWD1 aryl-acylamidase (EC 3.5.1.13) from bacterium CSBL00001 (see 2 papers)
    29% identity, 94% coverage of query (144 bits)

hydA / A0A0A1H115 4-hydroxybenzoate 1-phenylethylidene hydrazidase from Microbacterium hydrocarbonoxydans (see paper)
    28% identity, 97% coverage of query (142 bits)

5h6sC Crystal structure of hydrazidase s179a mutant complexed with a substrate (see paper)
    28% identity, 97% coverage of query (142 bits)

4yjiA / C3UWD1 The crystal structure of a bacterial aryl acylamidase belonging to the amidase signature (as) enzymes family (see paper)
    29% identity, 94% coverage of query (142 bits)

DUR1.2 / AAC41643.1 urea amidolyase from Saccharomyces cerevisiae (see paper)
    32% identity, 97% coverage of query (139 bits)

AMID_RHORH / P84650 Enantioselective amidase; EC 3.5.1.4 from Rhodococcus rhodochrous
    31% identity, 81% coverage of query (138 bits)

F6N111 aryl-acylamidase (EC 3.5.1.13) from Paracoccus sp. M1-1 (see paper)
G9FKH7 amidase (EC 3.5.1.4) from Paracoccus sp. (see paper)
    28% identity, 98% coverage of query (137 bits)

FAAH2 / Q6GMR7 fatty-acid amide hydrolase 2 (EC 3.5.1.99; EC 3.5.1.60) from Homo sapiens (see 2 papers)
FAAH2_HUMAN / Q6GMR7 Fatty-acid amide hydrolase 2; Amidase domain-containing protein; Anandamide amidohydrolase 2; Oleamide hydrolase 2; EC 3.5.1.99 from Homo sapiens (Human) (see 2 papers)
B2C6G4 fatty acid amide hydrolase (EC 3.5.1.99) from Homo sapiens (see paper)
Q6GMR7 amidase (EC 3.5.1.4); fatty acid amide hydrolase (EC 3.5.1.99) from Homo sapiens (see 2 papers)
    27% identity, 96% coverage of query (136 bits)

DUR1,2 / P32528 urea amidolyase (EC 6.3.4.6) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 6 papers)
DUR1_YEAST / P32528 Urea amidolyase; EC 6.3.4.6; EC 3.5.1.54 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P32528 allophanate hydrolase (EC 3.5.1.54); urea carboxylase (EC 6.3.4.6) from Saccharomyces cerevisiae (see 3 papers)
    32% identity, 97% coverage of query (135 bits)

DUR1_LACKL / A5H0J2 Urea amidolyase; Pyrimidine-degrading protein 13,15; Uracil catabolism protein 3,5; EC 6.3.4.6; EC 3.5.1.54 from Lachancea kluyveri (Yeast) (Saccharomyces kluyveri) (see paper)
    31% identity, 90% coverage of query (135 bits)

iaaH / P06618 indoleacetamide hydrolase (EC 3.5.1.4) from Pseudomonas savastanoi (see 3 papers)
    30% identity, 96% coverage of query (134 bits)

AMI1_ORYSJ / Q7XTK3 Amidase 1; OsAMI1; EC 3.5.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    32% identity, 85% coverage of query (129 bits)

AMI1 / Q9FR37 indole-3-acetamide amidohydrolase (EC 3.5.1.4) from Arabidopsis thaliana (see 5 papers)
AMI1_ARATH / Q9FR37 Amidase 1; AtAMI1; Translocon at the outer membrane of chloroplasts 64-I; AtTOC64-I; EC 3.5.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
    30% identity, 83% coverage of query (127 bits)

A0A1D8PDC6 allophanate hydrolase (EC 3.5.1.54) from Candida albicans (see paper)
    30% identity, 93% coverage of query (126 bits)

DUR1,2 likely multifunctional urea amidolyase from Candida albicans (see paper)
    30% identity, 93% coverage of query (126 bits)

AMI4G_ARATH / A0A1P8B760 Probable amidase At4g34880; EC 3.5.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    28% identity, 100% coverage of query (125 bits)

B7XBZ9 6-aminohexanoate-cyclic-dimer hydrolase (EC 3.5.2.12) from Cupriavidus sp. U124 (see 2 papers)
    31% identity, 96% coverage of query (124 bits)

B7XBZ7 6-aminohexanoate-cyclic-dimer hydrolase (EC 3.5.2.12) from Cupriavidus sp. T7 (see 2 papers)
B7XBZ8 6-aminohexanoate-cyclic-dimer hydrolase (EC 3.5.2.12) from Acidovorax sp. T31 (see 2 papers)
    31% identity, 96% coverage of query (123 bits)

Q0BRB0 allophanate hydrolase (EC 3.5.1.54) from Granulibacter bethesdensis (see 2 papers)
    33% identity, 87% coverage of query (122 bits)

4gysB / Q0BRB0 Granulibacter bethesdensis allophanate hydrolase co-crystallized with malonate (see paper)
    33% identity, 87% coverage of query (122 bits)

Q6CP22 allophanate hydrolase (EC 3.5.1.54); urea carboxylase (EC 6.3.4.6) from Kluyveromyces lactis (see 3 papers)
    31% identity, 90% coverage of query (122 bits)

Q9ALV2 allophanate hydrolase (EC 3.5.1.54) from Enterobacter cloacae (see 2 papers)
    29% identity, 91% coverage of query (118 bits)

libA / G3K3F8 linuron hydrolase from Variovorax sp. SRS16 (see 2 papers)
    29% identity, 99% coverage of query (111 bits)

atzF / Q936X2 allophanate hydrolase subunit from Pseudomonas sp. (strain ADP) (see 2 papers)
ATZF_PSESD / Q936X2 Allophanate hydrolase; EC 3.5.1.54 from Pseudomonas sp. (strain ADP) (see 2 papers)
Q936X2 allophanate hydrolase (EC 3.5.1.54) from Pseudomonas sp. ADP (see paper)
    30% identity, 92% coverage of query (109 bits)

1o9oA / Q9ZIV5 Crystal structure of the s131a mutant of malonamidase e2 complexed with malonamate from bradyrhizobium japonicum (see paper)
    28% identity, 96% coverage of query (98.2 bits)

1ocmA The crystal structure of malonamidase e2 covalently complexed with pyrophosphate from bradyrhizobium japonicum
    28% identity, 96% coverage of query (94.7 bits)

TOC64_PEA / Q9MUK5 Translocon at the outer membrane of chloroplasts 64 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see 4 papers)
TC 3.A.9.1.1 / Q9MUK5 Toc64 aka IAP64, component of Chloroplast envelope protein translocase (CEPT); outer membrane complex. The Tic20-like protein (acc # AUO68237.1; 413 aas, 6 TMSs in a 1 TMS (N-terminal) + 5 TMSs (C-terminal)), of the lower brown alga, Saccharina japonica, has been characterized from Pisum sativum (Garden pea) (see paper)
toc64 Toc64 from Pisum sativum
    26% identity, 72% coverage of query (71.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory