Sites on a Tree


Searching for up to 100 curated homologs for Pf1N1B4_1245 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_1245 (308 a.a.)

Found high-coverage hits (≥70%) to 6 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.2.18 / Q9WXW0 ABC-type transporter, integral membrane subunit, component of Xylose porter (Nanavati et al. 2006). Regulated by xylose-responsive regulator XylR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    32% identity, 98% coverage of query (146 bits)

TC 3.A.1.2.10 / O83343 Ribose/galactose ABC transporter, permease protein aka RbsC-2, component of The purine nucleoside permease (probably transports guanosine, adenosine, 2'-deoxyguanosine, inosine and xanthosine with decreasing affinity in this order) from Treponema pallidum (see paper)
    30% identity, 97% coverage of query (130 bits)

TC 3.A.1.2.12 / Q8DU39 RnsD, component of The (deoxy)ribonucleoside permease; probably takes up all deoxy- and ribonucleosides (cytidine, uridine, adenosine and toxic analogues, fluorocytidine and fluorouridine tested), but not ribose or nucleobases from Streptococcus mutans (see paper)
    32% identity, 94% coverage of query (124 bits)

NUPC_LACLM / A2RKA5 Nucleoside ABC transporter permease protein NupC from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
TC 3.A.1.2.17 / A2RKA5 Purine/cytidine ABC transporter permease protein, component of General nucleoside uptake porter, NupABC/BmpA (transports all common nucleosides as well as 5-fluorocytidine, inosine, deoxyuridine and xanthosine) (Martinussen et al., 2010) (Most similar to 3.A.1.2.12). NupA is 506aas with two ABC (C) domains. NupB has 8 predicted TMSs, NupC has 9 or 10 predicted TMSs in a 4 + 1 (or 2) + 4 arrangement from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    33% identity, 94% coverage of query (123 bits)

NUPQ_BACSU / O05255 Guanosine ABC transporter permease protein NupQ from Bacillus subtilis (strain 168) (see paper)
    33% identity, 100% coverage of query (117 bits)

Build an alignment

Build an alignment for Pf1N1B4_1245 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.2.28 / O83324 Conserved hypothetical integral membrane protein, component of Riboflavin uptake ABC transporter, RfuABCD from Treponema pallidum (strain Nichols)
    27% identity, 84% coverage of query (59.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory