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Searching for up to 100 curated homologs for Pf1N1B4_1271 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_1271 (450 a.a.)

Found high-coverage hits (≥70%) to 6 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q9HV22 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Pseudomonas aeruginosa (see paper)
    69% identity, 100% coverage of query (615 bits)

FABG4_MYCTU / I6Y778 3-oxoacyl-[acyl-carrier-protein] reductase [NADH]; Beta-ketoacyl CoA reductase; FASII-like 3-oxoacyl-thioester reductase; HMwFabG; EC 1.1.1.212 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 6 papers)
O53665 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Mycobacterium tuberculosis (see 2 papers)
    48% identity, 100% coverage of query (392 bits)

4fw8A / O53665 Crystal structure of fabg4 complexed with coenzyme nadh (see paper)
    49% identity, 96% coverage of query (386 bits)

3q6iA Crystal structure of fabg4 and coenzyme binary complex
    49% identity, 96% coverage of query (386 bits)

3v1uA Crystal structure of a beta-ketoacyl reductase fabg4 from mycobacterium tuberculosis h37rv complexed with NAD+ and hexanoyl-coa at 2.5 angstrom resolution
    49% identity, 95% coverage of query (372 bits)

5vp5A / A0QPE7 Crystal structure of a 3-oxoacyl-acyl-carrier protein reductase fabg4 from mycobacterium smegmatis bound to NAD
    48% identity, 94% coverage of query (370 bits)

Build an alignment

Build an alignment for Pf1N1B4_1271 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory