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Searching for up to 100 curated homologs for Pf1N1B4_2170 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_2170 (233 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q88B12 2-haloacid dehalogenase (configuration-inverting) (EC 3.8.1.10) from Pseudomonas syringae (see paper)
3vayA / Q88B12 Crystal structure of 2-haloacid dehalogenase from pseudomonas syringae pv. Tomato dc3000 (see paper)
    70% identity, 98% coverage of query (340 bits)

YigB / b3812 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase (EC 3.1.3.104; EC 3.1.3.102) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yigB / P0ADP0 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase (EC 3.1.3.104; EC 3.1.3.102) from Escherichia coli (strain K12) (see 4 papers)
YIGB_ECOLI / P0ADP0 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YigB; EC 3.1.3.104 from Escherichia coli (strain K12) (see 3 papers)
yigB / RF|NP_418257 uncharacterized protein yigB from Escherichia coli K12 (see 2 papers)
    33% identity, 97% coverage of query (121 bits)

PSP_THET2 / Q72H00 Phosphoserine phosphatase; PSP; EC 3.1.3.3 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
    35% identity, 88% coverage of query (97.4 bits)

Build an alignment

Build an alignment for Pf1N1B4_2170 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PSP_BACSU / P94512 Phosphoserine phosphatase; PSP; EC 3.1.3.3 from Bacillus subtilis (strain 168) (see paper)
    26% identity, 97% coverage of query (73.2 bits)

3qnmA / Q8A5G8 Haloalkane dehalogenase family member from bacteroides thetaiotaomicron of unknown function
    28% identity, 95% coverage of query (71.6 bits)

3i76B / O06480 The crystal structure of the orthorhombic form of the putative had- hydrolase yfnb from bacillus subtilis bound to magnesium reveals interdomain movement
    29% identity, 95% coverage of query (70.5 bits)

PYNA_STRR6 / Q8DPQ3 Pyrimidine 5'-nucleotidase PynA; Antimutator protein PynA; House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; Pyrimidine nucleotidase A; Ribonucleotide monophosphatase; EC 3.1.3.5 from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
    28% identity, 98% coverage of query (64.3 bits)

G3PP_METJA / Q58832 Glyceraldehyde 3-phosphate phosphatase; EC 3.1.3.- from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
    26% identity, 95% coverage of query (59.3 bits)

HAD_AGRTR / P60527 (S)-2-haloacid dehalogenase; 2-haloalkanoic acid dehalogenase; Cryptic L-isomer-specific dehalogenase; DhlS5I; Halocarboxylic acid halidohydrolase; L-2-haloacid dehalogenase; L-DEX; EC 3.8.1.2 from Agrobacterium tumefaciens (strain RS5) (see paper)
    26% identity, 97% coverage of query (54.3 bits)

4knvA / Q8TBE9 The crystal structure of apo human hdhd4 from se-mad (see paper)
    26% identity, 97% coverage of query (48.9 bits)

YhfE / b3385 phosphoglycolate phosphatase (EC 3.1.3.18) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gph / P32662 phosphoglycolate phosphatase (EC 3.1.3.18) from Escherichia coli (strain K12) (see 7 papers)
GPH_ECOLI / P32662 Phosphoglycolate phosphatase; PGP; PGPase; EC 3.1.3.18 from Escherichia coli (strain K12) (see 3 papers)
    27% identity, 95% coverage of query (47.8 bits)

1zrmA / Q53464 Crystal structure of the reaction intermediate of l-2-haloacid dehalogenase with 2-chloro-n-butyrate (see paper)
    26% identity, 94% coverage of query (47.4 bits)

Q83PX1 phosphoglycolate phosphatase (EC 3.1.3.18) from Shigella flexneri (see paper)
    27% identity, 95% coverage of query (47.4 bits)

HAD_PSEUY / Q53464 (S)-2-haloacid dehalogenase; 2-haloalkanoic acid dehalogenase; Halocarboxylic acid halidohydrolase; L-2-haloacid dehalogenase; L-DEX; EC 3.8.1.2 from Pseudomonas sp. (strain YL) (see 3 papers)
    26% identity, 94% coverage of query (47.0 bits)

Q9D7I5 phosphohistidine phosphatase (EC 3.9.1.3) from Mus musculus (see paper)
    30% identity, 73% coverage of query (47.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory