Searching for up to 100 curated homologs for Pf1N1B4_3565 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_3565 (118 a.a.)
Found high-coverage hits (≥70%) to 12 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q02I31 Putative pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Pseudomonas aeruginosa (strain UCBPP-PA14)
91% identity, 100% coverage of query (232 bits)
Q48G05 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Pseudomonas syringae (see paper)
92% identity, 100% coverage of query (227 bits)
PDL2_ARATH / Q6QJ72 Pterin-4-alpha-carbinolamine dehydratase 2, mitochondrial; 4-alpha-hydroxy-tetrahydropterin dehydratase; PCD/DCoH-like protein 2; EC 4.2.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
32% identity, 93% coverage of query (74.3 bits)
Build an alignment for Pf1N1B4_3565 and 3 homologs with ≥ 30% identity
Or download the sequences
ATP1_ARATH / Q9LU63 Probable pterin-4-alpha-carbinolamine dehydratase, chloroplastic; 4-alpha-hydroxy-tetrahydropterin dehydratase; PCD/DCoH-like protein 1; Protein AIRP2 TARGET PROTEIN 1; Protein SDIR1-INTERACTING PROTEIN 1; EC 4.2.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
27% identity, 92% coverage of query (57.4 bits)
Q2Q449 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Toxoplasma gondii (see paper)
30% identity, 75% coverage of query (48.5 bits)
2v6tB / Q2Q449 Crystal structure of a complex of pterin-4a-carbinolamine dehydratase from toxoplasma gondii with 7,8-dihydrobiopterin (see paper)
30% identity, 75% coverage of query (48.1 bits)
PHS_SCHPO / O42658 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Overlapping meiotic transcript 2; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
omt2 / RF|NP_594610.1 4-alpha-hydroxytetrahydrobiopterin dehydratase (predicted); EC 4.2.1.96 from Schizosaccharomyces pombe (see 2 papers)
32% identity, 76% coverage of query (46.6 bits)
PHS_MOUSE / P61458 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Mus musculus (Mouse) (see paper)
34% identity, 77% coverage of query (45.4 bits)
1f93A / P61459 Crystal structure of a complex between the dimerization domain of hnf-1 alpha and the coactivator dcoh (see paper)
34% identity, 77% coverage of query (45.4 bits)
PCBD1 / P61457 Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) from Homo sapiens (see paper)
PHS_HUMAN / P61457 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Homo sapiens (Human) (see 5 papers)
PHS_RAT / P61459 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Rattus norvegicus (Rat) (see 7 papers)
34% identity, 77% coverage of query (45.4 bits)
PHS2_MOUSE / Q9CZL5 Pterin-4-alpha-carbinolamine dehydratase 2; PHS 2; 4-alpha-hydroxy-tetrahydropterin dehydratase 2; DcoH-like protein DCoHm; Dimerization cofactor of hepatocyte nuclear factor 1 from muscle; HNF-1-alpha dimerization cofactor; EC 4.2.1.96 from Mus musculus (Mouse) (see paper)
32% identity, 86% coverage of query (45.1 bits)
1dcpA Dcoh, a bifunctional protein-binding transcriptional coactivator, complexed with biopterin
34% identity, 77% coverage of query (45.1 bits)
Or start over
Lawrence Berkeley National Laboratory