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Searching for up to 100 curated homologs for Pf1N1B4_3974 ABC transporter, ATP-binding protein (341 a.a.)

Found high-coverage hits (≥70%) to 53 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.20.2 / Q9KLQ5 Fe(3+) ions import ATP-binding protein FbpC, component of Hexose-phosphate transporter from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
    47% identity, 85% coverage of query (282 bits)

TC 3.A.1.1.24 / TC 3.A.1.1.25 / Q72L52 Sugar-binding transport ATP-binding protein aka MalK1 aka TT_C0211, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    43% identity, 99% coverage of query (273 bits)

TC 3.A.1.20.1 / O54370 BitD, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
    44% identity, 86% coverage of query (271 bits)

TC 3.A.1.1.5 / P54933 SmoK aka POLK, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) (see paper)
    46% identity, 88% coverage of query (269 bits)

Q8YM92 ABC-type polyamine transporter (subunit 3/3) (EC 7.6.2.11) from Nostoc sp. PCC 7120 = FACHB-418 (see paper)
    46% identity, 86% coverage of query (268 bits)

YagC / b0262 CP4-6 prophage; ABC transporter ATP-binding protein AfuC from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    46% identity, 85% coverage of query (267 bits)

TC 3.A.1.20.3 / A3N296 Ferric ABC transporter ATP-binding protein, component of Iron (Fe3+) uptake porter, AfuABC (FbpABC) (Chin et al. 1996). AfuA has been characterized from Actinobacillus pleuropneumoniae serotype 5b (strain L20)
    44% identity, 85% coverage of query (263 bits)

Ac3H11_2941 ABC transporter for D-Sorbitol, ATPase component from Acidovorax sp. GW101-3H11
    41% identity, 96% coverage of query (261 bits)

PGA1_c13180 ABC transporter for D-Sorbitol, ATPase component from Phaeobacter inhibens BS107
    41% identity, 99% coverage of query (261 bits)

PotG / b0855 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotG / P31134 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTG_ECOLI / P31134 Putrescine transport ATP-binding protein PotG; EC 7.6.2.16 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.2 / P31134 PotG aka B0855, component of Putrescine porter from Escherichia coli (see 4 papers)
    41% identity, 98% coverage of query (257 bits)

YdcT / b1441 putative ABC transporter ATP-binding protein YdcT from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ydcT / P77795 putative ABC transporter ATP-binding protein YdcT from Escherichia coli (strain K12) (see 3 papers)
YDCT_ECOLI / P77795 Uncharacterized ABC transporter ATP-binding protein YdcT from Escherichia coli (strain K12) (see paper)
    43% identity, 95% coverage of query (256 bits)

MALK_THELN / Q9YGA6 Trehalose/maltose import ATP-binding protein MalK; EC 7.5.2.1 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 5 papers)
    46% identity, 87% coverage of query (254 bits)

1g291 / Q9YGA6 Malk (see paper)
    46% identity, 87% coverage of query (254 bits)

TC 3.A.1.1.12 / Q9AI63 PalK, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
    41% identity, 95% coverage of query (254 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    41% identity, 91% coverage of query (253 bits)

TC 3.A.1.1.4 / Q01937 LacK, component of Lactose porter from Agrobacterium radiobacter (see paper)
    45% identity, 78% coverage of query (251 bits)

2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
    48% identity, 77% coverage of query (251 bits)

A0A142UTH4 ABC-type polyamine transporter (subunit 4/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
    39% identity, 98% coverage of query (251 bits)

BWI76_RS01840 maltose ABC transporter, ATPase component (MalK) from Klebsiella michiganensis M5al
    41% identity, 91% coverage of query (251 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    40% identity, 91% coverage of query (250 bits)

mtlK / Q4KC54 polyol ABC-type transporterATP-binding component MtlK from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    43% identity, 90% coverage of query (250 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    40% identity, 91% coverage of query (250 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    40% identity, 91% coverage of query (250 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    40% identity, 91% coverage of query (250 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    40% identity, 91% coverage of query (250 bits)

TC 3.A.1.11.7 / Q97Q42 Spermidine/putrescine import ATP-binding protein PotA, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
    39% identity, 98% coverage of query (249 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    42% identity, 83% coverage of query (249 bits)

SM_b20002 ABC transporter for Lactose, ATPase component from Sinorhizobium meliloti 1021
    40% identity, 91% coverage of query (249 bits)

1q12A Crystal structure of the atp-bound e. Coli malk
    40% identity, 90% coverage of query (249 bits)

SMc02869 N-Acetyl-D-glucosamine ABC transport system, ATPase component from Sinorhizobium meliloti 1021
    42% identity, 89% coverage of query (248 bits)

TC 3.A.1.1.16 / Q8TZQ3 MalK aka PF1933, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
    47% identity, 79% coverage of query (248 bits)

TC 3.A.1.11.3 / Q44383 MotB, component of Mannopine porter from Agrobacterium tumefaciens (see paper)
    43% identity, 90% coverage of query (248 bits)

TC 3.A.1.1.38 / Q9WYQ2 Glycerol-3-phosphate-transporting ATPase, component of Inositol phosphate porter (Rodionova et al. 2013). Binds inositol phosphate with low Kd and inositol with a lower affinity from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    41% identity, 92% coverage of query (247 bits)

TC 3.A.1.11.6 / Q1M7Q1 Putative ABC transporter component, component of The γ-aminobutyrate (GABA) uptake system, GtsABCD from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    41% identity, 97% coverage of query (247 bits)

Dshi_0546 ABC transporter for Xylitol, ATPase component from Dinoroseobacter shibae DFL-12
    42% identity, 86% coverage of query (246 bits)

TC 3.A.1.1.23 / P96483 MsiK protein, component of The cellobiose/cellotriose (and possibly higher cellooligosaccharides), CebEFGMsiK [MsiK functions to energize several ABC transporters including those for maltose/maltotriose and trehalose] from Streptomyces reticuli (see paper)
    44% identity, 81% coverage of query (246 bits)

8hprD Lpqy-sugabc in state 4
    46% identity, 80% coverage of query (246 bits)

8hprC Lpqy-sugabc in state 4
    46% identity, 80% coverage of query (246 bits)

TC 3.A.1.1.10 / Q9KWT9 AlgS, component of Alginate (MW 27,000 Da) (and Alginate oligosaccharides) uptake porter. Sphingomonas species A1 is a 'pit-forming' bacterium that directly incorporates alginate into its cytoplasm through a pit-dependent transport system, termed a 'superchannel' (Murata et al., 2008). The pit is a novel organ acquired through the fluidity and reconstitution of cell surface molecules, and through cooperation with the transport machinery in the cells. It confers upon bacterial cells a more efficient way to secure and assimilate macromolecules from Sphingomonas sp (see paper)
algS / BAB03314.1 AlgS from Sphingomonas sp (see paper)
    40% identity, 96% coverage of query (244 bits)

8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
    46% identity, 80% coverage of query (244 bits)

Pf6N2E2_1960 ABC transporter for D-sorbitol, ATPase component from Pseudomonas fluorescens FW300-N2E2
    41% identity, 92% coverage of query (244 bits)

1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
    41% identity, 100% coverage of query (243 bits)

MSMX_BACSU / P94360 Oligosaccharides import ATP-binding protein MsmX; Maltodextrin import ATP-binding protein MsmX; Melibiose/raffinose/stachyose import ATP-binding protein MsmX; EC 7.5.2.- from Bacillus subtilis (strain 168) (see 5 papers)
TC 3.A.1.1.26 / TC 3.A.1.1.34 / P94360 MsmX, component of The maltose porter, MdxEFG and MsmX from Bacillus subtilis (see 3 papers)
    43% identity, 79% coverage of query (243 bits)

AO356_00010 ABC transporter for D-Sorbitol, ATPase component from Pseudomonas fluorescens FW300-N2C3
    41% identity, 92% coverage of query (243 bits)

sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
    47% identity, 77% coverage of query (237 bits)

2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    39% identity, 85% coverage of query (216 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    38% identity, 80% coverage of query (199 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    38% identity, 80% coverage of query (199 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    38% identity, 80% coverage of query (199 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    36% identity, 85% coverage of query (195 bits)

2awnA / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    35% identity, 91% coverage of query (183 bits)

3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
    37% identity, 79% coverage of query (158 bits)

4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
    32% identity, 71% coverage of query (133 bits)

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Build an alignment for Pf1N1B4_3974 and 53 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory