Searching for up to 100 curated homologs for Pf1N1B4_4198 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_4198 (445 a.a.)
Found high-coverage hits (≥70%) to 45 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
GALT_PSEPU / E8ZB61 Gallate transporter; Gallate permease from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
galT / CBJ94499.1 gallic acid permease from Pseudomonas putida (see paper)
82% identity, 99% coverage of query (637 bits)
PCAK_ACIAD / Q43975 4-hydroxybenzoate transporter PcaK; 4-HB transporter from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
46% identity, 93% coverage of query (380 bits)
PCAK_PSEPU / Q51955 4-hydroxybenzoate transporter PcaK from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
TC 2.A.1.15.1 / Q51955 4-Hydroxybenzoate/protocatechuate porter from Pseudomonas putida (see paper)
pcaK / AAA85137.1 PcaK from Pseudomonas putida (see paper)
48% identity, 96% coverage of query (377 bits)
proT / BAB32694.1 putative transporter from Pseudomonas straminea (see 2 papers)
46% identity, 97% coverage of query (368 bits)
MHBT_KLEOX / Q5EXK5 3-hydroxybenzoate transporter MhbT from Klebsiella oxytoca (see paper)
42% identity, 96% coverage of query (318 bits)
TC 2.A.1.15.5 / O30513 Benzoate porter, BenK from Acinetobacter calcoaceticus (see 2 papers)
32% identity, 97% coverage of query (246 bits)
TC 2.A.1.15.7 / Q6FBB3 Aromatic compound (benzoate) uptake transporter of 450 aas from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
32% identity, 99% coverage of query (225 bits)
TC 2.A.1.15.6 / O24842 Vanillate porter, VanK (see 4 papers)
33% identity, 98% coverage of query (206 bits)
TC 2.A.1.15.14 / Q8VUZ0 Probable uptake transporter for 2,4-dichlorophenoxyacetic acid (2,4-D), CadK from Bradyrhizobium sp. HW13
33% identity, 88% coverage of query (203 bits)
YaiK / b0353 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpT / P77589 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
MHPT_ECOLI / P77589 3-(3-hydroxy-phenyl)propionate transporter; 3HPP transporter; 3-(3-hydroxy-phenyl)propionate:H(+) symporter; 3HPP:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.15.2 / P77589 MhpT. A specific 3-(3-hydroxyphenyl)propionate (3HPP) transporter; vital for E. coli K-12 W3110 to grow on this substrate from Escherichia coli (see 3 papers)
36% identity, 94% coverage of query (194 bits)
TC 2.A.1.15.3 / Q46M63 2,4-Dichlorophenoxyacetate porter (see 5 papers)
30% identity, 98% coverage of query (194 bits)
TC 2.A.1.15.11 / Q6M372 The Vanillate porter, VanK from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
32% identity, 95% coverage of query (173 bits)
Build an alignment for Pf1N1B4_4198 and 12 homologs with ≥ 30% identity
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NIAP_ACIAD / Q6FFF7 Niacin transporter NiaP from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
28% identity, 87% coverage of query (166 bits)
TC 2.A.1.15.8 / O24723 Probable 1-hydroxy-2-naphthoate transporter, orf1 (see paper)
27% identity, 93% coverage of query (154 bits)
genK / Q8NLB7 gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
GENK_CORGL / Q8NLB7 Gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
28% identity, 86% coverage of query (150 bits)
TC 2.A.1.15.4 / P94131 cis,cis-muconate porter, MucK from Acinetobacter calcoaceticus (see 2 papers)
mucK / AAC27117.1 cis,cis-muconate transport protein MucK from Acinetobacter baylyi (see paper)
27% identity, 91% coverage of query (115 bits)
NIAP_BACSU / O34691 Putative niacin/nicotinamide transporter NiaP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.82.4 / O34691 Niacin uptake porter NiaP from Bacillus subtilis (see 2 papers)
26% identity, 91% coverage of query (108 bits)
SVOP_BOVIN / Q1JP63 Synaptic vesicle 2-related protein; SV2-related protein from Bos taurus (Bovine) (see paper)
25% identity, 96% coverage of query (101 bits)
SVOP_XENLA / Q2XWK0 Synaptic vesicle 2-related protein; SV2-related protein from Xenopus laevis (African clawed frog) (see paper)
25% identity, 93% coverage of query (97.1 bits)
TC 2.A.1.82.1 / F2CRE4 The barley copper uptake porter, CT-1 of 749 aas; nearly identical to the wheat orthologue from Hordeum vulgare var. distichum
26% identity, 89% coverage of query (94.0 bits)
TC 2.A.1.15.9 / O51798 Probable 4-methylmuconolactone transporter, MmlH from Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) (see paper)
25% identity, 84% coverage of query (93.6 bits)
YaaU / b0045 putative transporter YaaU from Escherichia coli K-12 substr. MG1655 (see 4 papers)
26% identity, 81% coverage of query (90.5 bits)
SVOP_RAT / Q9Z2I7 Synaptic vesicle 2-related protein; SV2-related protein from Rattus norvegicus (Rat) (see paper)
25% identity, 96% coverage of query (87.8 bits)
TC 2.A.1.82.3 / Q8BFT9 Synaptic vesicle 2-related protein (SV2-related protein), SVOP from Mus musculus (see 4 papers)
24% identity, 92% coverage of query (85.5 bits)
ANTR1_ARATH / O82390 Sodium-dependent phosphate transport protein 1, chloroplastic; Anion transporter 1; Na(+)/PI cotransporter 1; Phosphate transporter PHT4;1; Sodium/phosphate cotransporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
O82390 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see 2 papers)
TC 2.A.1.14.22 / O82390 The chloroplast thylakoid Na+:phosphate symporter, ANTR1 (512aas) (Pavón et al., 2008). Residues essential for function have been identified from Arabidopsis thaliana (see 7 papers)
26% identity, 86% coverage of query (81.3 bits)
NanT / b3224 N-acetylneuraminate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 10 papers)
nanT / P41036 N-acetylneuraminate:H+ symporter from Escherichia coli (strain K12) (see 16 papers)
NANT_ECOLI / P41036 Sialic acid transporter NanT; Sialic acid permease; Sialic acid/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.12.1 / P41036 The sialic acid porter, NanT. N-acetylneuraminic acid (Neu5Ac) serves as a sole source of carbon and nitrogen for E. coli. It is a mucus-derived carbon source in the mammalian gut. NanT can also take up and allow efficient growth on the related sialic acids, N-glycolylneuraminic acid (Neu5Gc) and 3-keto-3-deoxy-d-glycero-d-galactonononic acid (KDN) from Escherichia coli (see 4 papers)
23% identity, 92% coverage of query (78.2 bits)
ANTR2_ARATH / Q8GX78 Ascorbate transporter, chloroplastic; Phosphate transporter PHT4;4; AtPHT4;4; Probable anion transporter 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
25% identity, 87% coverage of query (77.4 bits)
YdjE / b1769 putative transporter YdjE from Escherichia coli K-12 substr. MG1655 (see 3 papers)
TC 2.A.1.1.92 / P38055 Inner membrane metabolite transport protein YdjE from Escherichia coli (strain K12) (see 6 papers)
24% identity, 97% coverage of query (75.1 bits)
YgcS / b2771 putative transporter YgcS from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 2.A.1.1.95 / Q46909 Inner membrane metabolite transport protein YgcS from Escherichia coli (strain K12) (see 3 papers)
25% identity, 86% coverage of query (73.9 bits)
YdjK / b1775 putative transporter YdjK from Escherichia coli K-12 substr. MG1655 (see 3 papers)
26% identity, 76% coverage of query (73.2 bits)
8bw7A Cryo-em structure of rat slc22a6 bound to alpha-ketoglutaric acid
25% identity, 79% coverage of query (66.2 bits)
S22A7_MOUSE / Q91WU2 Solute carrier family 22 member 7; Organic anion transporter 2; mOAT2 from Mus musculus (Mouse) (see 3 papers)
28% identity, 74% coverage of query (63.9 bits)
S22A6_MOUSE / Q8VC69 Solute carrier family 22 member 6; Kidney-specific transport protein; Novel kidney transcript; mNKT; Organic anion transporter 1; mOAT1; Renal organic anion transporter 1; mROAT1 from Mus musculus (Mouse) (see 6 papers)
25% identity, 79% coverage of query (62.8 bits)
8bvsA Cryo-em structure of rat slc22a6 bound to tenofovir
24% identity, 79% coverage of query (62.8 bits)
8bvtA / O35956 Cryo-em structure of rat slc22a6 bound to probenecid (see paper)
24% identity, 79% coverage of query (62.8 bits)
S22A5_HUMAN / O76082 Organic cation/carnitine transporter 2; High-affinity sodium-dependent carnitine cotransporter; Solute carrier family 22 member 5 from Homo sapiens (Human) (see 28 papers)
TC 2.A.1.19.3 / O76082 The polyspecific organic cation (L- and D-carnitine, butyryl-L-carnitine, acetyl carnitine, γ-butyro-betaine, glycinebetaine, β-lactam antibiotics with a quaternary nitrogen such as cephaloridine, and others):Na+ symporter, OCTN2 (SLC22A5). Carnitine is transporter with high affinity (2 - 20 μM0 (Ingoglia et al. 2015). Associated with Crohn''s disease (Barton et al., 2005) as well as primary carnitine deficiency from Homo sapiens (Human) (see 28 papers)
25% identity, 84% coverage of query (60.5 bits)
S22A6_HUMAN / Q4U2R8 Solute carrier family 22 member 6; Organic anion transporter 1; hOAT1; PAH transporter; hPAHT; Renal organic anion transporter 1; hROAT1 from Homo sapiens (Human) (see 20 papers)
TC 2.A.1.19.31 / Q4U2R8 Solute carrier family 22 member 6 (Organic anion transporter 1) (hOAT1) (PAH transporter) (hPAHT) (Renal organic anion transporter 1) (hROAT1), from Homo sapiens (see 17 papers)
26% identity, 79% coverage of query (59.7 bits)
S22A6_PSEAM / O57379 Solute carrier family 22 member 6; Organic anion transporter 1; Renal organic anion transporter 1; ROAT1; fROAT1 from Pseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus) (see paper)
24% identity, 80% coverage of query (57.0 bits)
S22AB_HUMAN / Q9NSA0 Solute carrier family 22 member 11; Organic anion transporter 4; OAT4; Organic anion:dicarboxylate exchanger OAT4 from Homo sapiens (Human) (see 11 papers)
TC 2.A.1.19.10 / Q9NSA0 The apical proximal tubular kidney/placenta organic anion transporter 4, Oat4 (Slc22a11) (transports estrone sulfate (Km = 1 µM), dehydroepiandrosterone sulfate (Km = 60µM), many anionic drugs, diuretics, bile salts, urate and ochratoxin A). Catalyzes Na+-independent efflux, possibly using glutamate as a counter anion in an exchange reaction, especially in the placenta from Homo sapiens (Human) (see 7 papers)
SLC22A11 / GB|BAA95316.1 solute carrier family 22 member 11 from Homo sapiens
24% identity, 78% coverage of query (56.6 bits)
S22A3_HUMAN / O75751 Solute carrier family 22 member 3; Extraneuronal monoamine transporter; EMT; Organic cation transporter 3; OCT3 from Homo sapiens (Human) (see 11 papers)
TC 2.A.1.19.24 / O75751 Solute carrier family 22 member 3 (Extraneuronal monoamine transporter) (EMT) (Organic cation transporter 3) from Homo sapiens (see 3 papers)
27% identity, 78% coverage of query (54.7 bits)
7zh6A Structure of human oct3 in complex with inhibitor corticosterone
26% identity, 78% coverage of query (50.1 bits)
7zhaA / O75751 Structure of human oct3 in complex with inhibitor decynium-22 (see paper)
26% identity, 78% coverage of query (49.3 bits)
P36035 Carboxylic acid transporter protein homolog from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
25% identity, 83% coverage of query (45.8 bits)
VGLU2_RAT / Q9JI12 Vesicular glutamate transporter 2; VGluT2; Differentiation-associated BNPI; Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter; Solute carrier family 17 member 6 from Rattus norvegicus (Rat) (see 10 papers)
TC 2.A.1.14.16 / Q9JI12 The broad specificity brain synaptic vesicle anion transporter (transports glutamate in a Δψ-dependent fashion requiring Cl- but phosphate by a Na+-dependent mechanism via a different pathway/mechanism from Rattus norvegicus (see 8 papers)
24% identity, 78% coverage of query (44.7 bits)
7t3nA / Q9JI12 R184q/e191q mutant of rat vesicular glutamate transporter 2 (vglut2)
23% identity, 78% coverage of query (43.5 bits)
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Lawrence Berkeley National Laboratory