Searching for up to 100 curated homologs for Pf1N1B4_4790 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_4790 (356 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

Removed hits that are identical to the query, leaving 18

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PfGW456L13_2986 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens GW456-L13
    90% identity, 100% coverage of query (653 bits)

AO353_25665 3-hydroxy-isobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas fluorescens FW300-N2E3
    89% identity, 100% coverage of query (632 bits)

PS417_13835 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas simiae WCS417
    86% identity, 98% coverage of query (620 bits)

Psest_2439 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Pseudomonas stutzeri RCH2
    65% identity, 99% coverage of query (451 bits)

RR42_RS28545 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Cupriavidus basilensis FW507-4G11
    48% identity, 99% coverage of query (293 bits)

bch / Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see paper)
Q81DR3 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Bacillus cereus (see paper)
    35% identity, 97% coverage of query (257 bits)

Hibch / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Rattus norvegicus (see 5 papers)
HIBCH_RAT / Q5XIE6 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Rattus norvegicus (Rat) (see 2 papers)
    39% identity, 96% coverage of query (251 bits)

HIBCH_HUMAN / Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Homo sapiens (Human) (see 2 papers)
    36% identity, 98% coverage of query (235 bits)

3bptA / Q6NVY1 Crystal structure of human beta-hydroxyisobutyryl-coa hydrolase in complex with quercetin
    36% identity, 98% coverage of query (233 bits)

echA9 / O53419 steroid enoyl-CoA hydratase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    39% identity, 100% coverage of query (221 bits)

4hdtA / G7CC99 Crystal structure of a carnitinyl-coa dehydratase from mycobacterium thermoresistibile (see paper)
    38% identity, 98% coverage of query (216 bits)

HIBC1_ARATH / Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase 1; CoA-thioester hydrolase CHY1; EC 3.1.2.-; EC 3.1.2.4 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9LKJ1 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Arabidopsis thaliana (see paper)
    34% identity, 97% coverage of query (213 bits)

PGA1_c17350 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Phaeobacter inhibens BS107
    38% identity, 92% coverage of query (201 bits)

HIBCH_NEUCR / Q1K7A4 Small ribosomal subunit protein mS47; 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; HIB-CoA hydrolase; HIBYL-CoA-H; EC 3.1.2.4 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see paper)
    34% identity, 94% coverage of query (200 bits)

C3KM96 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) from Sinorhizobium fredii (see paper)
    39% identity, 93% coverage of query (186 bits)

Q9SE41 enoyl-CoA hydratase (EC 4.2.1.17) from Avicennia marina (see paper)
    30% identity, 90% coverage of query (177 bits)

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Build an alignment for Pf1N1B4_4790 and 16 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

EHD3 / Q5AI24 3-hydroxypropanonyl-CoA hydrolase (EC 3.1.2.4) from Candida albicans (strain SC5314 / ATCC MYA-2876) (see paper)
    29% identity, 92% coverage of query (170 bits)

Msed_2001 / A4YI89 3-hydroxypropionyl-CoA dehydratase (EC 4.2.1.116) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 2 papers)
HPCD_METS5 / A4YI89 3-hydroxypropionyl-coenzyme A dehydratase; 3-hydroxypropionyl-CoA dehydratase; EC 4.2.1.116 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see paper)
A4YI89 3-hydroxypropionyl-CoA dehydratase (EC 4.2.1.116) from Metallosphaera sedula (see 3 papers)
5zaiC / A4YI89 Crystal structure of 3-hydroxypropionyl-coa dehydratase from metallosphaera sedula (see paper)
    26% identity, 74% coverage of query (95.5 bits)

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