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Searching for up to 100 curated homologs for Pf1N1B4_549 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_549 (267 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
    32% identity, 97% coverage of query (115 bits)

6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
    32% identity, 97% coverage of query (114 bits)

6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
    32% identity, 97% coverage of query (112 bits)

Build an alignment

Build an alignment for Pf1N1B4_549 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
    26% identity, 96% coverage of query (107 bits)

EstN1 / K0IAM1 pimeloyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) from Nitrososphaera gargensis (strain Ga9.2) (see paper)
    29% identity, 96% coverage of query (106 bits)

2xuaH / Q13KT2 Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
    27% identity, 97% coverage of query (104 bits)

Q13KT2 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Paraburkholderia xenovorans (see 2 papers)
    27% identity, 97% coverage of query (104 bits)

Q0SH24 3-oxoadipate enol-lactonase (EC 3.1.1.24); 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) from Rhodococcus jostii (see paper)
    32% identity, 88% coverage of query (103 bits)

pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
    32% identity, 88% coverage of query (102 bits)

pcaD / AAF34270.1 beta-ketoadipate enol-lactone hydrolase from Agrobacterium tumefaciens (see 2 papers)
    29% identity, 93% coverage of query (94.4 bits)

AO353_17230 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas fluorescens FW300-N2E3
    32% identity, 75% coverage of query (93.2 bits)

4uhfA / A0A0M3KKY6 Structural studies of a thermophilic esterase from thermogutta terrifontis (l37a mutant with butyrate bound) (see paper)
    30% identity, 97% coverage of query (92.8 bits)

pcaD / AAC37150.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 11 papers)
    26% identity, 90% coverage of query (92.4 bits)

catD / AAC46435.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 8 papers)
    26% identity, 91% coverage of query (92.0 bits)

TGND_ACIAD / Q6F9F4 (E)-2-((N-methylformamido)methylene)succinate hydrolase; MFMS hydrolase; EC 3.5.1.- from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    28% identity, 92% coverage of query (91.7 bits)

4uheA Structural studies of a thermophilic esterase from thermogutta terrifontis (malate bound)
    30% identity, 95% coverage of query (91.7 bits)

4uhdA Structural studies of a thermophilic esterase from thermogutta terrifontis (acetate bound)
    30% identity, 95% coverage of query (91.7 bits)

pcaD / Q88N36 subunit of 3-oxoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
Q88N36 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Pseudomonas putida (see paper)
    26% identity, 89% coverage of query (85.5 bits)

5h3hB / K0ACL0 Esterase (eaest) from exiguobacterium antarcticum (see paper)
    25% identity, 95% coverage of query (84.0 bits)

4lxhA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 3- cl hopda (see paper)
    26% identity, 96% coverage of query (83.6 bits)

4lyeA Crystal structure of the s105a mutant of a c-c hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with substrate hopda
    26% identity, 96% coverage of query (83.6 bits)

4lxiA Crystal structure of the s105a mutant of a carbon-carbon bond hydrolase, dxnb2 from sphingomonas wittichii rw1, in complex with 5, 8-dif hopda
    26% identity, 96% coverage of query (83.6 bits)

BPOC_MYCTU / P9WNH1 Putative non-heme bromoperoxidase BpoC from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    26% identity, 94% coverage of query (83.2 bits)

O73957 carboxylesterase (EC 3.1.1.1) from Sulfolobus acidocaldarius (see paper)
    26% identity, 93% coverage of query (82.8 bits)

Q8KT44 carboxylesterase (EC 3.1.1.1) from Lacticaseibacillus casei (see paper)
    25% identity, 95% coverage of query (81.6 bits)

P96965 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas fluorescens (see 2 papers)
cumD / BAA12150.1 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase from Pseudomonas fluorescens (see paper)
    25% identity, 96% coverage of query (81.3 bits)

bphD / BAM76235.1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Janibacter sp. TYM3221 (see paper)
    26% identity, 94% coverage of query (80.9 bits)

flnE / BAC75995.1 meta cleavage compound hydrolase from Terrabacter sp. DBF63 (see paper)
    24% identity, 92% coverage of query (80.5 bits)

1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
    25% identity, 96% coverage of query (80.5 bits)

2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
    26% identity, 94% coverage of query (80.5 bits)

3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase
    26% identity, 96% coverage of query (80.5 bits)

3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase
    26% identity, 96% coverage of query (79.7 bits)

ESTE_PSEFL / P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 8 papers)
GI|951089 arylesterase; EC 1.-.-.-; EC 3.1.1.2 from Pseudomonas fluorescens (see 3 papers)
AAB60168.1 esterase from Pseudomonas fluorescens (see 2 papers)
    26% identity, 96% coverage of query (79.0 bits)

7p4kA Soluble epoxide hydrolase in complex with fl217
    24% identity, 93% coverage of query (79.0 bits)

3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog
    26% identity, 96% coverage of query (79.0 bits)

catD / BAA75208.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see paper)
catD / BAC82535.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see 3 papers)
    25% identity, 93% coverage of query (78.6 bits)

1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
    25% identity, 94% coverage of query (78.2 bits)

1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
    25% identity, 94% coverage of query (78.2 bits)

1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
    25% identity, 94% coverage of query (78.2 bits)

1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
    25% identity, 94% coverage of query (78.2 bits)

1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
    25% identity, 94% coverage of query (78.2 bits)

5fp0A Ligand complex structure of soluble epoxide hydrolase
    23% identity, 93% coverage of query (78.2 bits)

8pi1B / P22862 Bicyclic incypro pseudomonas fluorescens esterase (see paper)
    26% identity, 96% coverage of query (77.8 bits)

5alsA Ligand complex structure of soluble epoxide hydrolase
    23% identity, 93% coverage of query (77.8 bits)

Q84II3 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Janthinobacterium sp. J3 (see paper)
    29% identity, 96% coverage of query (77.4 bits)

5alrA Ligand complex structure of soluble epoxide hydrolase
    23% identity, 93% coverage of query (77.4 bits)

7a7gA Soluble epoxide hydrolase in complex with tk90
    23% identity, 93% coverage of query (77.0 bits)

5alvA Ligand complex structure of soluble epoxide hydrolase
    24% identity, 93% coverage of query (77.0 bits)

4c4zA Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with a8
    22% identity, 93% coverage of query (76.6 bits)

4c4xA Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with c9
    22% identity, 93% coverage of query (76.6 bits)

4jncA Soluble epoxide hydrolase complexed with a carboxamide inhibitor
    22% identity, 93% coverage of query (76.6 bits)

8qmzA Soluble epoxide hydrolase in complex with rk4
    22% identity, 93% coverage of query (76.6 bits)

6yl4A Soluble epoxide hydrolase in complex with 3-((r)-3-(1-hydroxyureido) but-1-yn-1-yl)-n-((s)-3-phenyl-3-(4-trifluoromethoxy)phenyl)propyl) benzamide
    22% identity, 93% coverage of query (76.6 bits)

6hgxA Soluble epoxide hydrolase in complex with 1-(4-((4-(tert-butyl) morpholin-2-yl)methoxy)phenyl)-3-cyclohexylurea
    22% identity, 93% coverage of query (76.6 bits)

6hgwA Soluble epoxide hydrolase in complex with 2-(4-fluorophenyl)-n-(4- phenoxybenzyl)ethanamine
    22% identity, 93% coverage of query (76.6 bits)

6hgvA Soluble epoxide hydrolase in complex with talinolol
    22% identity, 93% coverage of query (76.6 bits)

6fr2A Soluble epoxide hydrolase in complex with lk864
    22% identity, 93% coverage of query (76.6 bits)

3antA Human soluble epoxide hydrolase in complex with a synthetic inhibitor
    22% identity, 93% coverage of query (76.6 bits)

3ansA Human soluble epoxide hydrolase in complex with a synthetic inhibitor
    22% identity, 93% coverage of query (76.6 bits)

7ebaA Co-crystal of kurarinone with seh
    22% identity, 93% coverage of query (76.6 bits)

6i5gA X-ray structure of human soluble epoxide hydrolasE C-terminal domain (hseh ctd)in complex with 15d-pgj2
    22% identity, 93% coverage of query (76.6 bits)

4x6yA Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative
    22% identity, 93% coverage of query (76.6 bits)

4x6xA Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative
    22% identity, 93% coverage of query (76.6 bits)

hppC / AAB81313.1 2-hydroxy-6-ketonona-2,4-dienoate hydrolase from Rhodococcus globerulus (see paper)
    25% identity, 93% coverage of query (76.3 bits)

6kxhB / A0A0K2AJY3 Alp1u_y247f mutant in complex with fluostatin c (see paper)
    24% identity, 94% coverage of query (76.3 bits)

4c4yA Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with a4
    22% identity, 93% coverage of query (76.3 bits)

8qn0A Soluble epoxide hydrolase in complex with rk3
    22% identity, 93% coverage of query (76.3 bits)

3pdcA Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor
    22% identity, 93% coverage of query (76.3 bits)

4haiA / P34913 Crystal structure of human soluble epoxide hydrolase complexed with n- cycloheptyl-1-(mesitylsulfonyl)piperidine-4-carboxamide. (see paper)
    22% identity, 93% coverage of query (75.9 bits)

5ak6A Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5akiA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5ai8A Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

4od0A Crystal structure of human soluble epoxide hydrolase complexed with 1- (1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea
    22% identity, 93% coverage of query (75.9 bits)

3otqA Soluble epoxide hydrolase in complex with pyrazole antagonist
    22% identity, 93% coverage of query (75.9 bits)

3kooA Crystal structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

3i28A Crystal structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

3i1yA Crystal structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5am5A Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5am4A Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5am1A Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5am0A Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alzA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alyA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alxA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alwA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5aluA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5altA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alpA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5aloA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alnA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5almA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5allA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alkA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5aliA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alhA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5algA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5alfA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5aleA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5aldA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

5akzA Ligand complex structure of soluble epoxide hydrolase
    22% identity, 93% coverage of query (75.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory