Sites on a Tree

 

Searching for up to 100 curated homologs for Pf1N1B4_5638 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_5638 (310 a.a.)

Found high-coverage hits (≥70%) to 63 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YhjI / b3526 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178; EC 2.7.1.45) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
kdgK / P37647 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178) from Escherichia coli (strain K12) (see 4 papers)
KDGK_ECOLI / P37647 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain K12) (see paper)
    52% identity, 97% coverage of query (305 bits)

KDGK_ECOLW / E0J5J4 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / LMG 11080 / NBRC 13500 / NCIMB 8666 / NRRL B-766 / W) (see paper)
    52% identity, 97% coverage of query (304 bits)

kdgK / P45416 2-dehydro-3-deoxy-D-gluconate kinase (EC 2.7.1.178) from Dickeya dadantii (strain 3937) (see 2 papers)
KDGK_DICD3 / P45416 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    52% identity, 97% coverage of query (297 bits)

KDGK_PSEA6 / Q15UF1 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxy-D-gluconate kinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
    31% identity, 97% coverage of query (169 bits)

4ebuA / Q2CIP5 Crystal structure of a sugar kinase (target efi-502312) from oceanicola granulosus, with bound amp/adp crystal form i
    41% identity, 95% coverage of query (144 bits)

4eumA Crystal structure of a sugar kinase (target efi-502132) from oceanicola granulosus with bound amp, crystal form ii
    41% identity, 89% coverage of query (139 bits)

KDGK_THET8 / Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
    36% identity, 85% coverage of query (109 bits)

1v1aA / Q53W83 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
    36% identity, 85% coverage of query (109 bits)

1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp
    36% identity, 85% coverage of query (109 bits)

Build an alignment

Build an alignment for Pf1N1B4_5638 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

RR42_RS28860 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus basilensis FW507-4G11
    29% identity, 89% coverage of query (86.3 bits)

KDGK_THETE / Q704D0 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermoproteus tenax (see paper)
kdgK / CAF18464.1 2-Keto-3-deoxy-gluconate kinase from Thermoproteus tenax (see paper)
    26% identity, 93% coverage of query (83.6 bits)

STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
    26% identity, 85% coverage of query (70.9 bits)

scrK / P26420 fructokinase (EC 2.7.1.4) from Klebsiella pneumoniae (see paper)
SCRK_KLEPN / P26420 Fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / GB|CAA43322.1 fructokinase; EC 2.7.1.4 from Klebsiella pneumoniae (see paper)
scrK / CAA43322.1 fructokinase from Klebsiella pneumoniae (see paper)
    26% identity, 88% coverage of query (70.5 bits)

Dshi_2797 Fructokinase (EC 2.7.1.4) from Dinoroseobacter shibae DFL-12
    29% identity, 86% coverage of query (70.5 bits)

Atu3166 / A9CES5 tagatose kinase (EC 2.7.1.101) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
TAGK_AGRFC / A9CES5 Tagatose kinase; EC 2.7.1.101 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
    26% identity, 96% coverage of query (70.1 bits)

Q0K080 dehydrogluconokinase (EC 2.7.1.13); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus necator (see paper)
    26% identity, 94% coverage of query (68.6 bits)

scrK / GB|AAA08602.1 fructokinase; EC 2.7.1.4 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
scrK / CAA43323.1 fructokinase from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    25% identity, 89% coverage of query (66.6 bits)

2varA / Q97U29 Crystal structure of sulfolobus solfataricus 2-keto-3-deoxygluconate kinase complexed with 2-keto-3-deoxygluconate (see paper)
    21% identity, 93% coverage of query (66.6 bits)

kdgK / Q97U29 2-dehydro-3-deoxyglucono/2-dehydro-3-deoxygalactonokinase monomer (EC 2.7.1.178) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 3 papers)
KDGK_SACS2 / Q97U29 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxy-galactonokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; KDGal kinase; EC 2.7.1.178 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
Q97U29 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178) from Saccharolobus solfataricus (see 5 papers)
    21% identity, 93% coverage of query (66.6 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    28% identity, 87% coverage of query (65.9 bits)

P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
    27% identity, 85% coverage of query (64.3 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    26% identity, 89% coverage of query (63.9 bits)

Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    26% identity, 85% coverage of query (63.2 bits)

1tz3A / Q8ZKR2 Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
    26% identity, 85% coverage of query (60.5 bits)

3iq0B / A0A0H2VDX9 Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
    26% identity, 72% coverage of query (60.5 bits)

1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog
    26% identity, 85% coverage of query (60.5 bits)

PFKB_THETC / D9TT10 ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase; EC 2.7.1.11 from Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (see paper)
    18% identity, 95% coverage of query (60.1 bits)

2dcnA / Q96XN9 Crystal structure of 2-keto-3-deoxygluconate kinase from sulfolobus tokodaii complexed with 2-keto-6-phosphogluconate (alpha-furanose form)
    23% identity, 87% coverage of query (59.3 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    23% identity, 89% coverage of query (59.3 bits)

KDGK_SULTO / Q96XN9 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxy-D-gluconate kinase; KDG kinase; KDGK; EC 2.7.1.45 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
Q96XN9 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Sulfurisphaera tokodaii (see paper)
    23% identity, 87% coverage of query (59.3 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    22% identity, 86% coverage of query (59.3 bits)

5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
    23% identity, 85% coverage of query (59.3 bits)

A0A0H3AER7 fructokinase (EC 2.7.1.4) from Vibrio cholerae (see paper)
    23% identity, 85% coverage of query (58.9 bits)

cscK / GB|CAA57218.2 fructokinase; EC 2.7.1.4 from Escherichia coli (see paper)
    23% identity, 86% coverage of query (58.9 bits)

AO356_00035 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2C3
    25% identity, 88% coverage of query (58.2 bits)

Pf6N2E2_1965 Fructokinase (EC 2.7.1.4) from Pseudomonas fluorescens FW300-N2E2
    26% identity, 88% coverage of query (57.8 bits)

KDGK_BACSU / P50845 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Bacillus subtilis (strain 168) (see paper)
    23% identity, 89% coverage of query (57.8 bits)

Q4KD57 2-ketogluconokinase (EC 2.7.1.13) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    27% identity, 94% coverage of query (56.6 bits)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    26% identity, 78% coverage of query (56.2 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    26% identity, 78% coverage of query (55.1 bits)

SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    26% identity, 78% coverage of query (54.3 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    26% identity, 78% coverage of query (53.5 bits)

3lkiB / Q87CC0 Crystal structure of fructokinase with bound atp from xylella fastidiosa
    26% identity, 72% coverage of query (53.1 bits)

frk / GB|AAB52373.1 fructokinase; EC 2.7.1.4 from Rhizobium leguminosarum bv. trifolii (see paper)
    25% identity, 84% coverage of query (52.8 bits)

YdjH / b1772 L-glycero-L-galacto-octuluronate kinase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
ydjH / P77493 L-glycero-L-galacto-octuluronate kinase from Escherichia coli (strain K12) (see 2 papers)
    24% identity, 89% coverage of query (52.8 bits)

3in1A / P77493 Crystal structure of a putative ribokinase in complex with adp from e.Coli
    24% identity, 89% coverage of query (52.4 bits)

iolC / P42414 5-dehydro-2-deoxy-D-gluconate kinase (EC 2.7.1.92) from Bacillus subtilis (strain 168) (see 2 papers)
IOLC_BACSU / P42414 5-dehydro-2-deoxygluconokinase; 2-deoxy-5-keto-D-gluconate kinase; DKG kinase; EC 2.7.1.92 from Bacillus subtilis (strain 168) (see paper)
    24% identity, 87% coverage of query (51.6 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    21% identity, 90% coverage of query (51.2 bits)

2afbA / Q9WXS2 Crystal structure of 2-dehydro-3- deoxygluconokinase (ec 2.7.1.45) (tm0067) from thermotoga maritima at 2.05 a resolution (see paper)
    23% identity, 95% coverage of query (50.8 bits)

scrK / Q9ZHJ6 fructokinase (EC 2.7.1.4) from Clostridium beijerinckii (see paper)
    21% identity, 72% coverage of query (50.8 bits)

SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
    25% identity, 81% coverage of query (50.4 bits)

Q584S0 adenosine kinase (EC 2.7.1.20) from Trypanosoma brucei brucei (see paper)
4n09A / Q584S0 Structure of trypanosoma brucei brucei adenosine kinase in complex with adenosine and amppnp (see paper)
    25% identity, 88% coverage of query (50.4 bits)

FRLD_BACSU / O32153 Fructosamine kinase FrlD; EC 2.7.1.- from Bacillus subtilis (strain 168) (see paper)
O32153 fructoselysine 6-kinase (EC 2.7.1.218) from Bacillus subtilis (see paper)
    24% identity, 85% coverage of query (49.7 bits)

ADK_PHYPA / O49923 Adenosine kinase; AK; Adenosine 5'-phosphotransferase; EC 2.7.1.20 from Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens) (see paper)
    24% identity, 88% coverage of query (48.9 bits)

3otxA Crystal structure of trypanosoma brucei rhodesiense adenosine kinase complexed with inhibitor ap5a
    24% identity, 86% coverage of query (48.1 bits)

2xtbA Crystal structure of trypanosoma brucei rhodesiense adenosine kinase complexed with activator
    24% identity, 86% coverage of query (48.1 bits)

7fcaD / B2HEF4 Pfkb(mycobacterium marinum) (see paper)
    26% identity, 85% coverage of query (47.8 bits)

4xckA / A0A0H2UL04 Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion. (see paper)
    26% identity, 82% coverage of query (47.8 bits)

N515DRAFT_1919 Fructokinase (EC 2.7.1.4) from Dyella japonica UNC79MFTsu3.2
    27% identity, 86% coverage of query (46.6 bits)

6a8cA Ribokinase from leishmania donovani with adp
    24% identity, 96% coverage of query (46.6 bits)

6a8bA Ribokinase from leishmania donovani with amppcp
    24% identity, 96% coverage of query (46.6 bits)

6a8aA / A0A3S7X0F5 Ribokinase from leishmania donovani with atp (see paper)
    24% identity, 96% coverage of query (46.6 bits)

YhfQ / b3374 fructoselysine 6-kinase (EC 2.7.1.218) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
frlD / P45543 fructoselysine 6-kinase (EC 2.7.1.218) from Escherichia coli (strain K12) (see 3 papers)
FRLD_ECOLI / P45543 Fructoselysine 6-kinase; EC 2.7.1.218 from Escherichia coli (strain K12) (see 2 papers)
P45543 fructoselysine 6-kinase (EC 2.7.1.218) from Escherichia coli (see 3 papers)
    23% identity, 95% coverage of query (45.8 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory