Searching for up to 100 curated homologs for Pf1N1B4_683 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_683 (507 a.a.)

Found high-coverage hits (≥70%) to 11 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q141Z6 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Paraburkholderia xenovorans (see paper)
    75% identity, 99% coverage of query (790 bits)

FumA / b1612 fumarase A (EC 4.2.1.2; EC 5.3.2.2) from Escherichia coli K-12 substr. MG1655 (see 16 papers)
fumA / P0AC33 fumarase A (EC 4.2.1.2; EC 5.3.2.2) from Escherichia coli (strain K12) (see 15 papers)
FUMA_ECOLI / P0AC33 Fumarate hydratase class I, aerobic; Fumarase A; Oxaloacetate keto--enol-isomerase; OAAKE isomerase; Oxaloacetate tautomerase; EC 4.2.1.2; EC 5.3.2.2 from Escherichia coli (strain K12) (see 4 papers)
P0AC33 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Escherichia coli (see paper)
fumA fumarate hydratase class I, aerobic; EC 4.2.1.2 from Escherichia coli K12 (see 8 papers)
    34% identity, 88% coverage of query (205 bits)

FumB / b4122 fumarase B (EC 4.2.1.2; EC 4.2.1.81) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
fumB / P14407 fumarase B (EC 4.2.1.2; EC 4.2.1.81) from Escherichia coli (strain K12) (see 21 papers)
FUMB_ECOLI / P14407 Fumarate hydratase class I, anaerobic; D-tartrate dehydratase; Fumarase B; EC 4.2.1.2; EC 4.2.1.81 from Escherichia coli (strain K12) (see 3 papers)
P14407 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Escherichia coli (see paper)
fumB / GB|AAC77083.1 fumarate hydratase class I, anaerobic; EC 4.2.1.2 from Escherichia coli K12 (see 5 papers)
FumB / EW|b4122 anaerobic class I fumarate hydratase (fumarase B) from Escherichia coli K12 (see 3 papers)
    33% identity, 86% coverage of query (202 bits)

FUM2_LEIMA / E9AE57 Fumarate hydratase 2; Fumarase 2; LmFH-2; EC 4.2.1.2 from Leishmania major (see 3 papers)
    33% identity, 88% coverage of query (201 bits)

6uoiA Crystal structure of cytosolic fumarate hydratase from leishmania major in a complex with malonate
    32% identity, 88% coverage of query (196 bits)

6unzA / E9AE57 Crystal structure of cytosolic fumarate hydratase from leishmania major (see paper)
    32% identity, 88% coverage of query (195 bits)

6uqnB Crystal structure of r173a variant of cytosolic fumarate hydratase from leishmania major in a complex with fumarate and s-malate
    32% identity, 88% coverage of query (195 bits)

6msnA Crystal structure of cytosolic fumarate hydratase from leishmania major in a complex with inhibitor thiomalate
    32% identity, 88% coverage of query (195 bits)

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Build an alignment for Pf1N1B4_683 and 8 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

Q8X999 fumarate hydratase (EC 4.2.1.2) from Escherichia coli (see paper)
    29% identity, 96% coverage of query (190 bits)

6msoA / Q4QAU9 Crystal structure of mitochondrial fumarate hydratase from leishmania major in a complex with inhibitor thiomalate (see paper)
    31% identity, 90% coverage of query (173 bits)

FUM1_LEIMA / Q4QAU9 Fumarate hydratase 1, mitochondrial; Fumarase 1; LmFH-1; EC 4.2.1.2 from Leishmania major (see 2 papers)
    31% identity, 90% coverage of query (173 bits)

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