Searching for up to 100 curated homologs for Pf1N1B4_771 Glutamate Aspartate periplasmic binding protein precursor GltI (TC 3.A.1.3.4) (304 a.a.)
Found high-coverage hits (≥70%) to 67 curated proteins.
Removed hits that are identical to the query, leaving 66
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
AO353_16290 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
95% identity, 100% coverage of query (596 bits)
PfGW456L13_4770 ABC transporter for L-Asparagine and possibly other L-amino acids, periplasmic substrate-binding component from Pseudomonas fluorescens GW456-L13
93% identity, 100% coverage of query (550 bits)
GASBP_PSEAE / Q9I402 L-glutamate/L-aspartate-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TC 3.A.1.3.22 / Q9I402 Probable binding protein component of ABC transporter, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
79% identity, 99% coverage of query (507 bits)
TC 3.A.1.3.19 / Q88NY2 PP1071, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
80% identity, 100% coverage of query (483 bits)
2ia4B / A0A0H2UXX1 Crystal structure of novel amino acid binding protein from shigella flexneri
61% identity, 89% coverage of query (336 bits)
2vhaA Debp
61% identity, 89% coverage of query (336 bits)
GltI / b0655 glutamate/aspartate ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
GltI / P37902 glutamate/aspartate ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 3 papers)
GLTI_ECOLI / P37902 Glutamate/aspartate import solute-binding protein from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.3.4 / P37902 YBEJ aka GltI aka B0655, component of Glutamate/aspartate porter from Escherichia coli (see 6 papers)
gltI / GB|BAA35307.2 glutamate-aspartate periplasmic-binding protein from Escherichia coli K12 (see 6 papers)
60% identity, 89% coverage of query (332 bits)
8ovoA / P37902,P42212 X-ray structure of the sf-iglusnfr-s72a in complex with l-aspartate
59% identity, 80% coverage of query (295 bits)
GLNH_BACSU / O34563 ABC transporter glutamine-binding protein GlnH from Bacillus subtilis (strain 168) (see paper)
32% identity, 80% coverage of query (109 bits)
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
34% identity, 76% coverage of query (107 bits)
4zv2A An ancestral arginine-binding protein bound to glutamine
34% identity, 76% coverage of query (107 bits)
Build an alignment for Pf1N1B4_771 and 11 homologs with ≥ 30% identity
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2yjpA / Q5F5B5 Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
29% identity, 78% coverage of query (89.4 bits)
TcyJ / b1920 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
tcyJ / P0AEM9 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli (strain K12) (see 13 papers)
TCYJ_ECOLI / P0AEM9 L-cystine-binding protein TcyJ; CBP; Protein FliY; Sulfate starvation-induced protein 7; SSI7 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.3.10 / P0AEM9 Cystine-binding periplasmic protein FLIY aka CysX aka B1920, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 7 papers)
31% identity, 86% coverage of query (84.7 bits)
5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
31% identity, 79% coverage of query (84.3 bits)
6svfA / Q9WZ62 Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
28% identity, 79% coverage of query (82.0 bits)
TC 3.A.1.3.16 / Q0P9X8 PEB1A, component of Uptake system for glutamate and aspartate from Campylobacter jejuni (see 2 papers)
peb1A / RF|YP_002344319.1 major cell-binding factor from Campylobacter jejuni (see 3 papers)
peb1 / AAA02919.1 major cell-binding factor from Campylobacter jejuni (see paper)
28% identity, 88% coverage of query (80.1 bits)
2v25A / Q0P9X8 Structure of the campylobacter jejuni antigen peb1a, an aspartate and glutamate receptor with bound aspartate (see paper)
28% identity, 79% coverage of query (79.3 bits)
6h2tA / P96257 Glnh bound to glu, mycobacterium tuberculosis (see paper)
24% identity, 83% coverage of query (73.9 bits)
6h20A Glnh bound to asn, mycobacterium tuberculosis
24% identity, 83% coverage of query (73.9 bits)
6h1uA Glnh bound to asp, mycobacterium tuberculosis
24% identity, 83% coverage of query (73.9 bits)
4ymxA / Q8RCC4 Crystal structure of the substrate binding protein of an amino acid abc transporter (see paper)
28% identity, 77% coverage of query (73.2 bits)
cjaA / CAJ20048.1 glutamine-binding protein from Campylobacter jejuni (see paper)
27% identity, 78% coverage of query (70.1 bits)
1xt8B / Q0P9S0 Crystal structure of cysteine-binding protein from campylobacter jejuni at 2.0 a resolution (see paper)
26% identity, 78% coverage of query (67.8 bits)
TC 3.A.1.3.18 / Q8YPM9 NatF, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB (see paper)
26% identity, 75% coverage of query (67.8 bits)
Pf6N2E2_5660 L-Arginine ABC transporter, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
27% identity, 86% coverage of query (67.8 bits)
AO356_18700 L-Arginine ABC transporter, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
27% identity, 86% coverage of query (67.4 bits)
AO356_00480 ABC transporter for D-Glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
25% identity, 84% coverage of query (66.2 bits)
Pf6N2E2_2053 ABC transporter for D-Glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
25% identity, 84% coverage of query (65.9 bits)
2y7iA / Q8ZKA9 Structural basis for high arginine specificity in salmonella typhimurium periplasmic binding protein stm4351. (see paper)
25% identity, 76% coverage of query (65.9 bits)
Pf6N2E2_5402 ABC transporter for D-Alanine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
25% identity, 79% coverage of query (65.9 bits)
Pf1N1B4_3431 ABC transporter for L-Arginine and L-Citrulline, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N1B4
27% identity, 86% coverage of query (64.7 bits)
AO353_21710 ABC transporter for D-glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
25% identity, 84% coverage of query (63.2 bits)
5lomB / Q7D447 Crystal structure of the pbp soca from agrobacterium tumefaciens c58 in complex with dfg at 1.5 a resolution (see paper)
26% identity, 78% coverage of query (62.4 bits)
SMc02118 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, periplasmic substrate-binding component from Sinorhizobium meliloti 1021
27% identity, 77% coverage of query (62.4 bits)
5l9oB Crystal structure of agrobacterium tumefaciens c58 strain pbp soca in complex with glucopine
26% identity, 78% coverage of query (62.0 bits)
5l9oA Crystal structure of agrobacterium tumefaciens c58 strain pbp soca in complex with glucopine
26% identity, 78% coverage of query (62.0 bits)
AAPJ_RHIJ3 / Q52812 General L-amino acid-binding periplasmic protein AapJ from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see 2 papers)
TC 3.A.1.3.8 / Q52812 AapJ, component of General L-amino acid porter; transports basic and acidic amino acids preferentially, but also transports aliphatic amino acids (catalyzes both uptake and efflux) from Rhizobium leguminosarum (biovar viciae) (see 2 papers)
aapJ / CAA57933.1 general amino acid ABC type transporter from Rhizobium leguminosarum (see paper)
26% identity, 77% coverage of query (61.2 bits)
AO353_03055 ABC transporter for L-Arginine and L-Citrulline, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
26% identity, 86% coverage of query (60.1 bits)
YXEM_BACSU / P54952 Probable amino-acid-binding protein YxeM from Bacillus subtilis (strain 168) (see 2 papers)
25% identity, 79% coverage of query (58.5 bits)
2q2aA / D0VWX8 Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus (see paper)
27% identity, 76% coverage of query (58.2 bits)
ArgT / b2310 lysine/arginine/ornithine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
TC 3.A.1.3.1 / TC 3.A.1.3.29 / P09551 ArgT aka B2310, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (see 5 papers)
26% identity, 76% coverage of query (58.2 bits)
2pvuA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
27% identity, 76% coverage of query (58.2 bits)
2q2cA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
27% identity, 76% coverage of query (58.2 bits)
ARGBP_PSEAE / G3XD47 L-arginine-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
TC 3.A.1.3.11 / O50181 AotJ aka PA0888, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa (see 2 papers)
25% identity, 84% coverage of query (57.8 bits)
4z9nB / A0A0M3KL33 Abc transporter / periplasmic binding protein from brucella ovis with glutathione bound
27% identity, 72% coverage of query (57.8 bits)
ARGT_SALTY / P02911 Lysine/arginine/ornithine-binding periplasmic protein; LAO-binding protein from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 6 papers)
argT / RF|NP_461297.1 lysine/arginine/ornithine ABC transporter, periplasmic lysine/arginine/ornithine-binding protein ArgT from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
24% identity, 76% coverage of query (57.4 bits)
1lstA Three-dimensional structures of the periplasmic lysine-, arginine-, ornithine-binding protein with and without a ligand
24% identity, 76% coverage of query (57.4 bits)
1lahE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein
24% identity, 76% coverage of query (57.4 bits)
1lagE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein
24% identity, 76% coverage of query (57.4 bits)
1lafE / P02911 Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
24% identity, 76% coverage of query (57.4 bits)
5owfA Structure of a lao-binding protein mutant with glutamine
24% identity, 76% coverage of query (56.6 bits)
4zefA / Q837S0 Crystal structure of substrate binding domain 2 (sbd2) of abc transporter glnpq from enterococcus faecalis
25% identity, 71% coverage of query (53.5 bits)
3vv5A Crystal structure of ttc0807 complexed with (s)-2-aminoethyl-l- cysteine (aec)
24% identity, 81% coverage of query (53.5 bits)
3vvfA Crystal structure of ttc0807 complexed with arginine
24% identity, 81% coverage of query (53.1 bits)
3vveA Crystal structure of ttc0807 complexed with lysine
24% identity, 81% coverage of query (53.1 bits)
3vvdA / Q72JG5 Crystal structure of ttc0807 complexed with ornithine (see paper)
24% identity, 81% coverage of query (53.1 bits)
4ohnA / A0A0H2UKY8 Crystal structure of an abc uptake transporter substrate binding protein from streptococcus pneumoniae with bound histidine
21% identity, 80% coverage of query (53.1 bits)
4i62A / A0A0H2ZN67 1.05 angstrom crystal structure of an amino acid abc transporter substrate-binding protein abpa from streptococcus pneumoniae canada mdr_19a bound to l-arginine
23% identity, 80% coverage of query (52.0 bits)
HISJ_SALTY / P02910 Histidine-binding periplasmic protein; HBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
hisJ / GB|AAV76512.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Salmonella enterica subsp. enterica serovar Typhimurium (see 5 papers)
24% identity, 76% coverage of query (50.8 bits)
1hslA / P0AEU0 Refined 1.89 angstroms structure of the histidine-binding protein complexed with histidine and its relationship with many other active transport(slash)chemosensory receptors (see paper)
24% identity, 76% coverage of query (50.4 bits)
3k4uE / Q7MAG0 Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
24% identity, 77% coverage of query (50.4 bits)
4gvoA / Q8Y4T3 Putative l-cystine abc transporter from listeria monocytogenes
25% identity, 76% coverage of query (50.1 bits)
4h5fA Crystal structure of an amino acid abc transporter substrate-binding protein from streptococcus pneumoniae canada mdr_19a bound to l- arginine, form 1
23% identity, 78% coverage of query (50.1 bits)
4kqpA / Q9CES5 Crystal structure of lactococcus lactis glnp substrate binding domain 2 (sbd2) in complex with glutamine at 0.95 a resolution (see paper)
23% identity, 72% coverage of query (46.6 bits)
HisJ / b2309 histidine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
HISJ_ECOLI / P0AEU0 Histidine-binding periplasmic protein; HBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.29 / P0AEU0 Histidine-binding periplasmic protein, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
hisJ / GB|AAC75369.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Escherichia coli (see 7 papers)
23% identity, 76% coverage of query (46.6 bits)
2ylnA / Q5F9M1 Crystal structure of the l-cystine solute receptor of neisseria gonorrhoeae in the closed conformation (see paper)
25% identity, 81% coverage of query (46.2 bits)
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