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Searching for up to 100 curated homologs for Pf6N2E2_1059 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1059 (548 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

celB / AAA21561.1 phosphoglucomutase from Komagataeibacter xylinus (see paper)
    64% identity, 99% coverage of query (719 bits)

A0A0H3NJ17 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
Q8ZQW9 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    60% identity, 99% coverage of query (643 bits)

2fuvA / Q8ZQW9 Phosphoglucomutase from salmonella typhimurium.
    60% identity, 98% coverage of query (642 bits)

pgmA / I6Y2G3 phosphoglucomutase (EC 5.4.2.2) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
I6Y2G3 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Mycobacterium tuberculosis (see paper)
    62% identity, 99% coverage of query (636 bits)

Blu / b0688 phosphoglucomutase (EC 5.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
pgm / P36938 phosphoglucomutase (EC 5.4.2.2) from Escherichia coli (strain K12) (see 11 papers)
PGM_ECOLI / P36938 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Escherichia coli (strain K12) (see 2 papers)
pgm / GB|ABB65241.1 phosphoglucomutase; EC 5.4.2.2 from Escherichia coli K12 (see 6 papers)
    60% identity, 99% coverage of query (636 bits)

Build an alignment

Build an alignment for Pf6N2E2_1059 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PGM_DROME / Q9VUY9 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Drosophila melanogaster (Fruit fly) (see paper)
    26% identity, 88% coverage of query (103 bits)

PGMMM_THEKO / Q68BJ6 Phosphoglucomutase/phosphomannomutase; PGM/PMM; EC 5.4.2.2; EC 5.4.2.8 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
    26% identity, 88% coverage of query (101 bits)

PH0923 / O58651 phosphomannose mutase (EC 5.4.2.8) from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
1wqaA / O58651 Crystal structure of pyrococcus horikoshii phosphomannomutase/phosphoglucomutase complexed with mg2+
    26% identity, 88% coverage of query (100 bits)

PGM1 / P33401 phosphoglucomutase-1 (EC 5.4.2.2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 6 papers)
PGM1_YEAST / P33401 Phosphoglucomutase 1; PGM 1; Glucose phosphomutase 1; EC 5.4.2.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
    29% identity, 75% coverage of query (100 bits)

pgcA / P18159 α-phosphoglucomutase (EC 5.4.2.2) from Bacillus subtilis (strain 168) (see paper)
PGCA_BACSU / P18159 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Bacillus subtilis (strain 168) (see 2 papers)
    26% identity, 88% coverage of query (94.0 bits)

PGM1_RABIT / P00949 Phosphoglucomutase-1; PGM 1; Glucose phosphomutase 1; EC 5.4.2.2 from Oryctolagus cuniculus (Rabbit) (see 3 papers)
    26% identity, 70% coverage of query (91.3 bits)

3pmgA Structure of rabbit muscle phosphoglucomutase at 2.4 angstroms resolution. Use of freezing point depressant and reduced temperature to enhance diffractivity
    26% identity, 70% coverage of query (91.3 bits)

1c4gA Phosphoglucomutase vanadate based transition state analog complex
    26% identity, 70% coverage of query (91.3 bits)

1c47A Binding driven structural changes in crystaline phosphoglucomutase associated with chemical reaction
    26% identity, 70% coverage of query (91.3 bits)

pgmA / CAB96418.1 phosphoglucomutase from Streptococcus thermophilus (see paper)
    25% identity, 88% coverage of query (89.7 bits)

PGM1 / P36871 phosphoglucomutase-1 (EC 5.4.2.2) from Homo sapiens (see 3 papers)
PGM1_HUMAN / P36871 Phosphoglucomutase-1; PGM 1; Glucose phosphomutase 1; EC 5.4.2.2 from Homo sapiens (Human) (see 8 papers)
P36871 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Homo sapiens (see 4 papers)
    27% identity, 70% coverage of query (88.6 bits)

PGCA_STAA8 / Q2FVC1 Phosphoglucomutase; PGM; Alpha-phosphoglucomutase; Glucose phosphomutase; EC 5.4.2.2 from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
    24% identity, 91% coverage of query (88.2 bits)

7s0wB / P36871 Crystal structure of the t337m variant of human pgm-1 (see paper)
    27% identity, 70% coverage of query (87.8 bits)

6y8yA / A0A6P3VN15 Structure of baltic herring (clupea harengus) phosphoglucomutase 5 (pgm5) with bound glucose-1-phosphate (see paper)
    27% identity, 83% coverage of query (87.0 bits)

5jn5A Crystal structure of the d263y missense variant of human pgm1
    27% identity, 70% coverage of query (84.7 bits)

7pjcB / A0A1D8PSA9 The structure of candida albicans phosphoglucomutase with isothiazolone modification on cys359
    26% identity, 79% coverage of query (84.3 bits)

Q670S5 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Trypanosoma cruzi (see paper)
    27% identity, 81% coverage of query (82.0 bits)

PGM_EMENI / Q9P931 Phosphoglucomutase; PGM; Glucose phosphomutase; EC 5.4.2.2 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
pgmB phosphoglucomutase; EC 5.4.2.2 from Emericella nidulans (see paper)
    25% identity, 83% coverage of query (79.3 bits)

Q4QCF1 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (EC 5.4.2.2) from Leishmania major (see paper)
    27% identity, 83% coverage of query (76.3 bits)

4qg5A / Q4QCF1 Crystal structure of phosphoglucomutase from leishmania major at 3.5 angstrom resolution
    27% identity, 83% coverage of query (75.9 bits)

PGM2 / Q96G03 phosphoglucomutase-2 (EC 5.4.2.2; EC 5.4.2.7) from Homo sapiens (see 2 papers)
PGM2_HUMAN / Q96G03 Phosphopentomutase; Glucose phosphomutase 2; Phosphodeoxyribomutase; Phosphoglucomutase-2; EC 5.4.2.7; EC 5.4.2.2 from Homo sapiens (Human) (see 2 papers)
    25% identity, 74% coverage of query (63.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory