Searching for up to 100 curated homologs for Pf6N2E2_1615 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1615 (331 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ALKR4_ARATH / Q93ZN2 Probable aldo-keto reductase 4; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
52% identity, 98% coverage of query (327 bits)
AKR1_SOYBN / C6TBN2 Probable aldo-keto reductase 1; GmAKR1; EC 1.1.1.- from Glycine max (Soybean) (Glycine hispida) (see paper)
47% identity, 96% coverage of query (291 bits)
YAKC_SCHPO / Q09923 Aldo-keto reductase yakc [NADP(+)]; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
yak3 aldose reductase YakC from Schizosaccharomyces pombe (see 3 papers)
47% identity, 90% coverage of query (286 bits)
STR7_STRTC / A0A3B1EFQ1 Aldo-keto reductase str7; Strobilurin A biosynthesis cluster protein r7; EC 1.1.1.- from Strobilurus tenacellus (see 3 papers)
47% identity, 97% coverage of query (282 bits)
PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
45% identity, 92% coverage of query (271 bits)
3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
44% identity, 92% coverage of query (245 bits)
FDB38_GIBM7 / W7N2Q9 Aldo-keto reductase FVEG_12638; Fusarium detoxification of benzoxazolinone cluster 2 protein FVEG_12638; FDB2 cluster protein FVEG_12638; EC 1.1.1.- from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) (see 4 papers)
38% identity, 95% coverage of query (206 bits)
FDB25_FUSPC / K3VD70 Aldo-keto reductase FPSE_08125; Fusarium detoxification of benzoxazolinone cluster protein FPSE_08125; FDB cluster protein FPSE_08125; EC 1.1.1.- from Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot fungus) (see 3 papers)
40% identity, 83% coverage of query (201 bits)
PLR1_SCHPO / O14295 Pyridoxal reductase; PL reductase; PL-red; EC 1.1.1.65 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
plr1 / RF|NP_594584.1 pyridoxal reductase Plr1; EC 1.1.1.65 from Schizosaccharomyces pombe (see 3 papers)
37% identity, 95% coverage of query (195 bits)
PLR2_SCHPO / O94521 Probable pyridoxal reductase 2; PL reductase 2; PL-red 2; EC 1.1.1.65 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
34% identity, 97% coverage of query (177 bits)
GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
36% identity, 94% coverage of query (174 bits)
1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
35% identity, 94% coverage of query (171 bits)
F2YCN5 D-xylose reductase (EC 1.1.1.307) from Zymomonas mobilis subsp. mobilis (see paper)
33% identity, 90% coverage of query (171 bits)
IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
33% identity, 94% coverage of query (168 bits)
6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
34% identity, 93% coverage of query (167 bits)
Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
34% identity, 93% coverage of query (167 bits)
6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
34% identity, 93% coverage of query (167 bits)
5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
34% identity, 93% coverage of query (167 bits)
1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
33% identity, 94% coverage of query (166 bits)
6ow0B / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
35% identity, 94% coverage of query (163 bits)
YH5B_SCHPO / O94315 Uncharacterized oxidoreductase C215.11c; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
34% identity, 89% coverage of query (160 bits)
8hnqA / A0A6B8QJ47 The structure of a alcohol dehydrogenase akr13b2 with NADP
34% identity, 89% coverage of query (159 bits)
6ow0A / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
34% identity, 94% coverage of query (159 bits)
YEZB_SCHPO / O14125 Uncharacterized oxidoreductase C3A11.11c; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
31% identity, 89% coverage of query (147 bits)
mtmW / Q194Q1 mithramycin dehydrogenase from Streptomyces argillaceus (see 2 papers)
33% identity, 94% coverage of query (147 bits)
Q5FQJ0 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
33% identity, 79% coverage of query (146 bits)
Gpr / b3001 L-glyceraldehyde 3-phosphate reductase from Escherichia coli K-12 substr. MG1655 (see 9 papers)
gpr / Q46851 L-glyceraldehyde 3-phosphate reductase (EC 1.1.1.21) from Escherichia coli (strain K12) (see 7 papers)
GPR_ECOLI / Q46851 L-glyceraldehyde 3-phosphate reductase; GAP reductase; EC 1.1.1.- from Escherichia coli (strain K12) (see 4 papers)
32% identity, 93% coverage of query (143 bits)
4aubB / Q46851 The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
32% identity, 93% coverage of query (143 bits)
YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
30% identity, 93% coverage of query (138 bits)
3n6qD Crystal structure of yghz from e. Coli
32% identity, 93% coverage of query (138 bits)
4aubE The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate
31% identity, 92% coverage of query (133 bits)
KCAB_ORYSJ / Q40648 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Oryza sativa subsp. japonica (Rice) (see paper)
31% identity, 90% coverage of query (132 bits)
6hg6A / A0A1S8QGT2 Clostridium beijerinckii aldo-keto reductase cbei_3974 with NADPH (see paper)
30% identity, 94% coverage of query (131 bits)
5t79A / Q8ZNA1 X-ray crystal structure of a novel aldo-keto reductases for the biocatalytic conversion of 3-hydroxybutanal to 1,3-butanediol (see paper)
33% identity, 94% coverage of query (129 bits)
Build an alignment for Pf6N2E2_1615 and 34 homologs with ≥ 30% identity
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KCAB_ARATH / O23016 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; Potassium voltage beta 1; KV-beta1; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
29% identity, 90% coverage of query (129 bits)
YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
32% identity, 90% coverage of query (129 bits)
VRDA_ASPPA / B9WYE6 Versiconal hemiacetal acetate reductase; VHA reductase; EC 1.1.1.353 from Aspergillus parasiticus (see paper)
B9WYE6 versiconal hemiacetal acetate reductase (EC 1.1.1.353) from Aspergillus parasiticus (see paper)
28% identity, 97% coverage of query (128 bits)
YI7E_SCHPO / Q9P7U2 Putative aryl-alcohol dehydrogenase C977.14c; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
30% identity, 91% coverage of query (128 bits)
YPR127W / Q06494 pyridoxine 4-dehydrogenase (EC 1.1.1.65) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
PLR1_YEAST / Q06494 Putative pyridoxal reductase; PL reductase; PL-red; EC 1.1.1.65 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
30% identity, 94% coverage of query (126 bits)
8hw0A / A0A6B8QIS5 The structure of akr6d1
29% identity, 95% coverage of query (125 bits)
4aubF / Q46851 The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
30% identity, 93% coverage of query (124 bits)
AMT2_ALTAL / Q75ZG2 Aldo-keto reductase AMT2; AM-toxin biosynthesis protein 2; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
29% identity, 94% coverage of query (124 bits)
3erpA Structure of idp01002, a putative oxidoreductase from and essential gene of salmonella typhimurium
32% identity, 94% coverage of query (124 bits)
PK81H_PSEFD / M2YMU7 Aldo-keto reductase MYCFIDRAFT_87468; PKS8-1 gene cluster protein MYCFIDRAFT_87468; EC 1.1.1.- from Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease fungus) (Mycosphaerella fijiensis) (see 2 papers)
29% identity, 80% coverage of query (122 bits)
AFTS1_ALTAL / Q75ZG3 Aldo-keto reductase AFTS1; AF-toxin biosynthesis protein S1; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
30% identity, 94% coverage of query (120 bits)
STCV_EMENI / Q00727 Norsolorinic acid reductase stcV; Sterigmatocystin biosynthesis cluster protein V; EC 1.1.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 8 papers)
stcV putative sterigmatocystin biosynthesis dehydrogenase stcV; EC 1.1.1.- from Emericella nidulans (see paper)
31% identity, 91% coverage of query (116 bits)
KCAB_SCHPO / O59826 Putative voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
29% identity, 93% coverage of query (115 bits)
CSH1 member of aldo-keto reductase family from Candida albicans (see 5 papers)
28% identity, 93% coverage of query (115 bits)
SAN2_FUSV7 / C7ZBE5 Aldo-keto reductase NECHADRAFT_45914; Sansalvamide biosynthesis cluster protein NECHADRAFT_45914; EC 1.1.1.- from Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4) (Fusarium solani subsp. pisi) (see paper)
28% identity, 93% coverage of query (114 bits)
6ciaA / A6T7Q7 Crystal structure of aldo-keto reductase from klebsiella pneumoniae in complex with NADPH.
30% identity, 93% coverage of query (114 bits)
4wghA Crystal structure of aldo/keto reductase from klebsiella pneumoniae in complex with NADP and acetate at 1.8 a resolution
30% identity, 93% coverage of query (113 bits)
IFD6 aldo-keto reductase family member from Candida albicans (see paper)
29% identity, 93% coverage of query (112 bits)
YeaE / b1781 methylglyoxal reductase YeaE from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yeaE / P76234 methylglyoxal reductase YeaE (EC 1.1.1.21) from Escherichia coli (strain K12) (see 3 papers)
32% identity, 92% coverage of query (112 bits)
eryBII / A4F7P4 dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-α-D-allose-forming) from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see 2 papers)
32% identity, 86% coverage of query (111 bits)
AAD16_YEAST / Q02895 Putative aryl-alcohol dehydrogenase AAD16; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
29% identity, 93% coverage of query (110 bits)
KCAB3_XENLA / Q9PTM4 Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3; EC 1.1.1.- from Xenopus laevis (African clawed frog) (see paper)
27% identity, 96% coverage of query (108 bits)
AFLE_ASPPU / Q00258 Norsolorinic acid reductase A; Aflatoxin biosynthesis protein E; EC 1.1.1.- from Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) (see 2 papers)
nor / AAC49166.1 norsolorinic acid reductase from Aspergillus parasiticus (see paper)
28% identity, 91% coverage of query (108 bits)
7wf3C / Q13303 Composite map of human kv1.3 channel in apo state with beta subunits (see paper)
27% identity, 94% coverage of query (107 bits)
KCAB2_HUMAN / Q13303 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; hKvbeta2; EC 1.1.1.- from Homo sapiens (Human) (see 4 papers)
27% identity, 94% coverage of query (107 bits)
YgdS / b2834 putative NADP(H)-dependent aldo-keto reductase Tas from Escherichia coli K-12 substr. MG1655 (see 6 papers)
1lqaA / P0A9T4 Tas protein from escherichia coli in complex with NADPH (see paper)
tas protein Tas from Escherichia coli str. K12 substr. MG1655 (see paper)
31% identity, 93% coverage of query (107 bits)
P0A9T4 Protein tas from Escherichia coli (strain K12)
31% identity, 93% coverage of query (107 bits)
3eauA Voltage-dependent k+ channel beta subunit in complex with cortisone
27% identity, 94% coverage of query (107 bits)
1exbA Structure of the cytoplasmic beta subunit-t1 assembly of voltage- dependent k channels
27% identity, 94% coverage of query (106 bits)
KCAB2_MOUSE / P62482 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; Neuroimmune protein F5; EC 1.1.1.- from Mus musculus (Mouse) (see 8 papers)
KCAB2_RAT / P62483 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Rattus norvegicus (Rat) (see 19 papers)
27% identity, 94% coverage of query (106 bits)
KCAB1_RAT / P63144 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Rattus norvegicus (Rat) (see 9 papers)
27% identity, 90% coverage of query (104 bits)
KCAB1_HUMAN / Q14722 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Homo sapiens (Human) (see 13 papers)
27% identity, 90% coverage of query (102 bits)
smoB / A9CEY6 6-dehydroglucose reductase monomer (EC 1.1.1.432) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
DHGRD_AGRFC / A9CEY6 6-dehydroglucose reductase; SQ monooxygenase cluster protein B; EC 1.1.1.432 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
27% identity, 79% coverage of query (94.0 bits)
P76187 Oxidoreductase YdhF; EC 1.-.-.- from Escherichia coli (strain K12)
29% identity, 90% coverage of query (94.0 bits)
5c7hA / Q92NR7 Crystal structure of aldo-keto reductase from sinorhizobium meliloti 1021 in complex with NADPH
31% identity, 91% coverage of query (92.8 bits)
4pmjA Crystal structure of a putative oxidoreductase from sinorhizobium meliloti 1021 in complex with NADP
31% identity, 91% coverage of query (92.8 bits)
7svqA / Q6BDJ2 Crystal structure of l-galactose dehydrogenase from spinacia oleracea in complex with NAD+ (see paper)
27% identity, 91% coverage of query (92.8 bits)
7bc1A / A9CEY6 Crystal structure of aldo-keto reductase from agrobacterium tumefaciens in a ternary complex with NADPH and glucose (see paper)
27% identity, 79% coverage of query (92.8 bits)
1og6C / P76187 Ydhf, an aldo-keto reductase from e.Coli complexed with NADPH
29% identity, 90% coverage of query (92.8 bits)
7ezlA Rice l-galactose dehydrogenase (holo form)
28% identity, 91% coverage of query (89.7 bits)
7eziA / Q2QQV2 Rice l-galactose dehydrogenase (apo form)
28% identity, 91% coverage of query (89.7 bits)
7twzA / A0A0H3GP70 Crystal structure of NADP-linked putative oxidoreductase from klebsiella pneumoniae
28% identity, 91% coverage of query (89.4 bits)
5z6tA / P31867 Crystal structure of d-xylose reductase from scheffersomyces stipitis in complex with NADPH (see paper)
27% identity, 91% coverage of query (80.9 bits)
2bp1A Structure of the aflatoxin aldehyde reductase in complex with NADPH
32% identity, 76% coverage of query (78.2 bits)
AKR7A2 / O43488 aflatoxin B1 aldehyde reductase member 2 from Homo sapiens (see 4 papers)
ARK72_HUMAN / O43488 Aflatoxin B1 aldehyde reductase member 2; AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; SSA reductase; EC 1.1.1.n11 from Homo sapiens (Human) (see 3 papers)
31% identity, 86% coverage of query (78.2 bits)
3krbA / A8BGX6 Structure of aldose reductase from giardia lamblia at 1.75a resolution (see paper)
27% identity, 76% coverage of query (77.8 bits)
5jh2A / A2T1W7 Crystal structure of the holo form of akr4c7 from maize (see paper)
29% identity, 83% coverage of query (73.9 bits)
XYL1_CANBO / Q8X195 NADPH-dependent D-xylose reductase; XR; EC 1.1.1.307 from Candida boidinii (Yeast) (see 5 papers)
Q8X195 D-xylose reductase (EC 1.1.1.307) from [Candida] boidinii (see paper)
25% identity, 92% coverage of query (73.2 bits)
7x3oA Crystal structure of aldo-keto reductase 1c3 complexed with compound s07054
25% identity, 92% coverage of query (68.9 bits)
4falA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 3-((3,4-dihydroisoquinolin-2(1h)-yl)sulfonyl)-n- methylbenzamide (80)
24% identity, 92% coverage of query (68.2 bits)
3ufyA Akr1c3 complex with r-naproxen
24% identity, 92% coverage of query (68.2 bits)
3r94A Akr1c3 complex with flurbiprofen
24% identity, 92% coverage of query (68.2 bits)
3r8hA Akr1c3 complex with zomepirac
24% identity, 92% coverage of query (68.2 bits)
3r8gA Akr1c3 complex with ibuprofen
24% identity, 92% coverage of query (68.2 bits)
3r7mA Akr1c3 complex with sulindac
24% identity, 92% coverage of query (68.2 bits)
3r6iA Akr1c3 complex with meclofenamic acid
24% identity, 92% coverage of query (68.2 bits)
3uweA Akr1c3 complexed with 3-phenoxybenzoic acid
25% identity, 92% coverage of query (68.2 bits)
3r58A Akr1c3 complex with naproxen
24% identity, 92% coverage of query (68.2 bits)
4xvdA 17beta-hsd5 in complex with 4-nitro-2-({4-[3-(trifluoromethyl) phenyl]piperazin-1-yl}methyl)phenol
25% identity, 92% coverage of query (67.8 bits)
4hmnA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (4-(4-chlorophenyl)piperazin-1-yl)(morpholino) methanone (24)
25% identity, 92% coverage of query (67.0 bits)
4h7cA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 1-{4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl}-2- pyrrolidinone
25% identity, 92% coverage of query (67.0 bits)
4fa3A Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (r)-1-(naphthalen-2-ylsulfonyl)piperidine-3- carboxylic acid (86)
25% identity, 92% coverage of query (67.0 bits)
3r43A Akr1c3 complexed with mefenamic acid
25% identity, 92% coverage of query (67.0 bits)
XYL1_CANTE / O74237 NAD(P)H-dependent D-xylose reductase; XR; EC 1.1.1.307 from Candida tenuis (Yeast) (Yamadazyma tenuis) (see 4 papers)
O74237 D-xylose reductase (EC 1.1.1.307) from Yamadazyma tenuis (see 5 papers)
25% identity, 91% coverage of query (66.6 bits)
1mi3A 1.8 angstrom structure of xylose reductase from candida tenuis in complex with NAD
25% identity, 91% coverage of query (66.6 bits)
1k8cB / O74237 Crystal structure of dimeric xylose reductase in complex with NADP(h) (see paper)
25% identity, 91% coverage of query (66.6 bits)
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