Searching for up to 100 curated homologs for Pf6N2E2_1646 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1646 (450 a.a.)
Found high-coverage hits (≥70%) to 39 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Pf1N1B4_5112 sucrose ABC transporter, substrate-binding component from Pseudomonas fluorescens FW300-N1B4
93% identity, 87% coverage of query (758 bits)
TC 3.A.1.1.25 / Q72H68 Trehalose/maltose-binding protein aka TT_C1627, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
43% identity, 94% coverage of query (355 bits)
6jahA Crystal structure of abc transporter alpha-glycoside-binding protein in complex with glucose
45% identity, 87% coverage of query (353 bits)
6jagA Crystal structure of abc transporter alpha-glycoside-binding protein in complex with sucrose
45% identity, 87% coverage of query (353 bits)
6jadA Crystal structure of abc transporter alpha-glycoside-binding protein in complex with palatinose
45% identity, 87% coverage of query (353 bits)
6j9yA Crystal structure of abc transporter alpha-glycoside-binding protein in complex with maltose
45% identity, 87% coverage of query (353 bits)
6jamA / Q5SLD7 Crystal structure of abc transporter alpha-glycoside-binding mutant protein r356a in complex with trehalose (see paper)
45% identity, 87% coverage of query (350 bits)
6jaiA Crystal structure of abc transporter alpha-glycoside-binding mutant protein d118a in complex with maltose
45% identity, 87% coverage of query (350 bits)
6jb0A Crystal structure of abc transporter alpha-glycoside-binding mutant protein w287a in complex with trehalose
45% identity, 87% coverage of query (347 bits)
TC 3.A.1.1.19 / Q8L126 PalE, component of Platinose (isomaltulose) (6-O-α-D-glucopyranosyl-D-fructofuranose) porter from Agrobacterium tumefaciens (see 3 papers)
palE / BAB96538.1 PalE from Agrobacterium tumefaciens (see 3 papers)
43% identity, 97% coverage of query (341 bits)
SM_b20325 ABC transporter for D-trehalose/D-maltose/sucrose, substrate-binding component (ThuE) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q7 ThuE aka RB0311 aka SMB20325, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
45% identity, 82% coverage of query (340 bits)
TC 3.A.1.1.12 / Q9AI68 PalE, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
40% identity, 94% coverage of query (330 bits)
6dtqA / G4XU73 Maltose bound t. Maritima male3 (see paper)
38% identity, 87% coverage of query (277 bits)
TC 3.A.1.1.41 / G4FGN8 Extracellular solute-binding protein family 1, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
38% identity, 87% coverage of query (277 bits)
TC 3.A.1.1.7 / O51923 MalE aka PF1739, component of Maltose/trehalose porter (see paper)
32% identity, 90% coverage of query (202 bits)
1eu8A / Q7LYW7 Structure of trehalose maltose binding protein from thermococcus litoralis (see paper)
33% identity, 88% coverage of query (202 bits)
MALE_THELN / Q7LYW7 Trehalose/maltose-binding protein MalE; TMBP from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 4 papers)
32% identity, 90% coverage of query (200 bits)
smoF / A9CEY9 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol binding protein from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
SMOF_AGRFC / A9CEY9 Sulfoquinovosyl glycerol-binding protein SmoF; SQGro-binding protein SmoF; SQ monooxygenase cluster protein F from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see 2 papers)
32% identity, 93% coverage of query (197 bits)
7qhvAAA / A9CEY9 7qhvAAA (see paper)
33% identity, 83% coverage of query (194 bits)
7ofyA Crystal structure of sq binding protein from agrobacterium tumefaciens in complex with sulfoquinovosyl glycerol (sqgro)
33% identity, 83% coverage of query (192 bits)
7yzsAAA Sulfoquinovosyl binding protein
33% identity, 82% coverage of query (191 bits)
7yzuA Crystal structure of the sulfoquinovosyl binding protein smof complexed with sqme
33% identity, 82% coverage of query (187 bits)
Build an alignment for Pf6N2E2_1646 and 22 homologs with ≥ 30% identity
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LPQY_MYCT3 / G7CES0 Trehalose-binding lipoprotein LpqY; Extracellular solute-binding protein; SugABC transporter substrate-binding protein LpqY; SugABC transporter SBP LpqY from Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile) (see paper)
26% identity, 72% coverage of query (86.3 bits)
7apeA / G7CES0 Crystal structure of lpqy from mycobacterium thermoresistible in complex with trehalose (see paper)
27% identity, 72% coverage of query (85.9 bits)
5iaiA / B9JM84 Crystal structure of abc transporter solute binding protein arad_9887 from agrobacterium radiobacter k84, target efi-510945 in complex with ribitol
23% identity, 77% coverage of query (75.9 bits)
8jadA Crystal structure of mycobacterium tuberculosis lpqy in complex with trehalose analogue yb-17
25% identity, 72% coverage of query (74.3 bits)
8jacA Crystal structure of mycobacterium tuberculosis lpqy in complex with trehalose analogue yb-16
25% identity, 72% coverage of query (74.3 bits)
8ja9A Crystal structure of mycobacterium tuberculosis lpqy in complex with trehalose analogue yb-03
25% identity, 72% coverage of query (74.3 bits)
lpqY / P9WGU9 trehalose-binding lipoprotein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
LPQY_MYCTU / P9WGU9 Trehalose-binding lipoprotein LpqY; SugABC transporter substrate-binding protein LpqY; SugABC transporter SBP LpqY from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / Q7D8J9 PROBABLE SUGAR-BINDING LIPOPROTEIN LPQY, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
25% identity, 72% coverage of query (73.9 bits)
8ja7E / P9WGU9 Cryo-em structure of mycobacterium tuberculosis lpqy-sugabc in complex with trehalose
25% identity, 72% coverage of query (73.9 bits)
8jabA Crystal structure of mycobacterium tuberculosis lpqy in complex with trehalose analogue yb-06
25% identity, 72% coverage of query (73.9 bits)
Q92AS8 ABC-type beta-glucan transporter (EC 7.5.2.3) from Listeria innocua (see paper)
23% identity, 75% coverage of query (65.9 bits)
5ysdB / Q92AS8 Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophorotriose (see paper)
24% identity, 75% coverage of query (65.5 bits)
5ysdA Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophorotriose
24% identity, 75% coverage of query (65.5 bits)
5ysbA Crystal structure of beta-1,2-glucooligosaccharide binding protein in ligand-free form
24% identity, 74% coverage of query (64.7 bits)
PGA1_c13210 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Phaeobacter inhibens BS107
25% identity, 72% coverage of query (62.0 bits)
2gh9A / Q72I44 Thermus thermophilus maltotriose binding protein bound with maltotriose (see paper)
25% identity, 71% coverage of query (62.0 bits)
HSERO_RS17000 ABC transporter for D-sorbitol/xylitol, substrate-binding component from Herbaspirillum seropedicae SmR1
24% identity, 74% coverage of query (57.8 bits)
2zyoA / Q9AJF5 Crystal structure of cyclo/maltodextrin-binding protein complexed with maltotetraose (see paper)
25% identity, 76% coverage of query (53.1 bits)
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Lawrence Berkeley National Laboratory