Searching for up to 100 curated homologs for Pf6N2E2_1718 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1718 (194 a.a.)
Found high-coverage hits (≥70%) to 55 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
trpG / BAC65123.1 anthranilate synthase component II from Burkholderia multivorans (see paper)
51% identity, 96% coverage of query (184 bits)
pabA / P28819 4-amino-4-deoxychorismate synthase; anthranilate synthase (subunit II) (EC 2.6.1.123) from Bacillus subtilis (strain 168) (see paper)
PABA_BACSU / P28819 Aminodeoxychorismate/anthranilate synthase component 2; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 2; Aminodeoxychorismate synthase, glutamine amidotransferase component; EC 2.6.1.85; EC 4.1.3.27 from Bacillus subtilis (strain 168) (see paper)
47% identity, 97% coverage of query (184 bits)
TRPG_PSEPU / P00901 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
50% identity, 96% coverage of query (180 bits)
trpG / P20576 anthranilate synthase β subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TRPG_PSEAE / P20576 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P20576 anthranilate synthase (subunit 2/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
49% identity, 96% coverage of query (174 bits)
para-aminobenzoate synthase glutamine amidotransferase component II / b3360 aminodeoxychorismate synthase subunit 2 (EC 2.6.1.85) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pabA / P00903 aminodeoxychorismate synthase subunit 2 (EC 2.6.1.85) from Escherichia coli (strain K12) (see 9 papers)
PABA_ECOLI / P00903 Aminodeoxychorismate synthase component 2; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 2; Aminodeoxychorismate synthase, glutamine amidotransferase component; EC 2.6.1.85 from Escherichia coli (strain K12) (see 3 papers)
P00903 aminodeoxychorismate synthase (EC 2.6.1.85); 2-amino-4-deoxychorismate synthase (EC 2.6.1.86) from Escherichia coli (see paper)
48% identity, 96% coverage of query (171 bits)
trpG / AAD09117.1 anthranilate synthase component II from Rhodobacter sphaeroides (see paper)
47% identity, 96% coverage of query (167 bits)
TRPG_YEAST / P00937 Multifunctional tryptophan biosynthesis protein; EC 4.1.3.27; EC 4.1.1.48 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
44% identity, 96% coverage of query (162 bits)
trpC anthranilate synthase component 2; EC 4.1.3.27 from Emericella nidulans (see 4 papers)
44% identity, 97% coverage of query (154 bits)
TRPG_AZOBR / P26922 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Azospirillum brasilense (see paper)
44% identity, 96% coverage of query (150 bits)
trpG anthranilate synthase component II; EC 4.1.3.27 from Leptospira biflexa serovar Patoc (see paper)
42% identity, 98% coverage of query (147 bits)
pabAB / P32483 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces griseus (see 5 papers)
ADCS_STRGR / P32483 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoic acid synthase; PABA synthase; EC 2.6.1.85 from Streptomyces griseus (see paper)
46% identity, 96% coverage of query (143 bits)
trpG / Q06129 anthranilate synthase β subunit (EC 4.1.3.27) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
TRPG_SACS2 / Q06129 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q06129 anthranilate synthase (subunit 1/2) (EC 4.1.3.27) from Saccharolobus solfataricus (see paper)
42% identity, 96% coverage of query (139 bits)
ASB2_ORYSJ / Q764B9 Anthranilate synthase beta subunit 2, chloroplastic; OsASB2; Anthranilate synthase, glutamine amidotransferase component 2-2; EC 4.1.3.27 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
41% identity, 96% coverage of query (134 bits)
ASB1_ORYSJ / Q7XUS2 Anthranilate synthase beta subunit 1, chloroplastic; OsASB1; Anthranilate synthase, glutamine amidotransferase component 2-1; EC 4.1.3.27 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
40% identity, 96% coverage of query (132 bits)
ASB1_ARATH / Q42565 Anthranilate synthase beta subunit 1, chloroplastic; Anthranilate synthase component 2-1; Anthranilate synthase, glutamine amidotransferase component 2-1; Protein TRYPTOPHAN BIOSYNTHESIS 4; Protein WEAK ETHYLENE INSENSITIVE 7; EC 4.1.3.27 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
40% identity, 96% coverage of query (130 bits)
ADCS_STRPR / P72539 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; EC 2.6.1.85 from Streptomyces pristinaespiralis (see paper)
43% identity, 96% coverage of query (129 bits)
TrpD / b1263 anthranilate synthase subunit TrpD (EC 2.4.2.18; EC 4.1.3.27) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
trpD / P00904 anthranilate synthase subunit TrpD (EC 2.4.2.18) from Escherichia coli (strain K12) (see 2 papers)
TRPGD_ECOLI / P00904 Bifunctional protein TrpGD; EC 4.1.3.27; EC 2.4.2.18 from Escherichia coli (strain K12) (see 3 papers)
37% identity, 99% coverage of query (122 bits)
TRPGD_SALTY / P00905 Bifunctional protein TrpGD; EC 4.1.3.27; EC 2.4.2.18 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
37% identity, 99% coverage of query (120 bits)
TRPG_SERMA / P00900 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Serratia marcescens (see paper)
36% identity, 99% coverage of query (119 bits)
ADCS_SCHPO / O94277 Putative aminodeoxychorismate synthase; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
34% identity, 97% coverage of query (117 bits)
papA / BAD21140.1 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae (see paper)
42% identity, 96% coverage of query (117 bits)
8hx8A / Q6L8Q5 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae co-crystallized with chorismate (see paper)
42% identity, 96% coverage of query (117 bits)
cmlB / F2RB79 4-amino-4-deoxychorismate synthase (EC 2.6.1.85) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see 2 papers)
ADCS_STRVP / F2RB79 Aminodeoxychorismate synthase; ADC synthase; 4-amino-4-deoxychorismate synthase; p-aminobenzoate synthase; EC 2.6.1.85 from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
42% identity, 96% coverage of query (116 bits)
1i7qB / P00900 Anthranilate synthase from s. Marcescens (see paper)
36% identity, 99% coverage of query (116 bits)
A0A060IGN1 aminodeoxychorismate synthase (EC 2.6.1.85) from Agaricus bisporus (see paper)
37% identity, 96% coverage of query (107 bits)
phnB / P09786 PhnB anthranilate synthase subunit (EC 4.1.3.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
PHNB_PSEAE / P09786 Anthranilate synthase component 2, pyocyanine specific; AS; ASII; Anthranilate synthase beta subunit, pyocyanine specific; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
P09786 anthranilate synthase (subunit 1/2) (EC 4.1.3.27) from Pseudomonas aeruginosa (see paper)
39% identity, 97% coverage of query (105 bits)
ADCS / Q8LPN3 aminodeoxychorismate synthase (EC 2.6.1.85) from Arabidopsis thaliana (see 2 papers)
ADCS_ARATH / Q8LPN3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; Protein EMBRYO DEFFECTIVE 1997; EC 2.6.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
31% identity, 96% coverage of query (103 bits)
ADCS / Q6TAS3 aminodeoxychorismate synthase (EC 2.6.1.85) from Solanum lycopersicum (see 2 papers)
ADCS_SOLLC / Q6TAS3 Aminodeoxychorismate synthase, chloroplastic; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
31% identity, 96% coverage of query (99.0 bits)
pabaA para-aminobenzoic acid synthase from Emericella nidulans (see 2 papers)
34% identity, 89% coverage of query (91.7 bits)
pabaA / GI|4885032 para aminobenzoic acid synthetase from Aspergillus fumigatus (see paper)
34% identity, 89% coverage of query (91.3 bits)
carA / CAB89872.1 carbamoyl phosphate synthetase small subunit from Lactococcus lactis (see paper)
34% identity, 78% coverage of query (87.0 bits)
Build an alignment for Pf6N2E2_1718 and 31 homologs with ≥ 30% identity
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O59071 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Pyrococcus horikoshii (see paper)
29% identity, 96% coverage of query (79.0 bits)
CARA_LACPL / P77885 Carbamoyl phosphate synthase pyrimidine-specific small chain; Carbamoyl phosphate synthetase glutamine chain 2; CPS-P; EC 6.3.5.5 from Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum) (see paper)
34% identity, 77% coverage of query (73.6 bits)
carA / CAA68238.2 carbamoyl-phosphate synthase small subunit from Lactobacillus plantarum subsp. plantarum (see 3 papers)
33% identity, 71% coverage of query (73.6 bits)
pyrAa1 / CAJ75871.1 PyrAa1 protein from Lactobacillus plantarum subsp. plantarum (see paper)
34% identity, 77% coverage of query (73.2 bits)
CARA_ARATH / Q9LVW7 Carbamoyl phosphate synthase small chain, chloroplastic; Carbamoyl phosphate synthetase glutamine chain; Protein VENOSA 6; EC 6.3.5.5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
29% identity, 96% coverage of query (72.8 bits)
Q8RSS4 carbamoyl-phosphate synthase (glutamine-hydrolysing) (subunit 2/2) (EC 6.3.5.5) from Halomonas eurihalina (see paper)
31% identity, 80% coverage of query (71.6 bits)
CARX_GEOSE / P54324 Carbamoyl phosphate synthase arginine-specific small chain; Carbamoyl phosphate synthetase glutamine chain; EC 6.3.5.5 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see paper)
32% identity, 82% coverage of query (71.2 bits)
ADCS_YEAST / P37254 Aminodeoxychorismate synthase; ADC synthase; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthase; EC 2.6.1.85 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
32% identity, 97% coverage of query (71.2 bits)
G3XCK6 2-amino-4-deoxychorismate synthase (EC 2.6.1.86) from Pseudomonas aeruginosa (see paper)
Q7DC81 aminodeoxychorismate synthase (EC 2.6.1.85) from Pseudomonas aeruginosa (see paper)
30% identity, 97% coverage of query (69.7 bits)
pyrAA / P25993 pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit) (EC 6.3.5.5) from Bacillus subtilis (strain 168) (see 4 papers)
CARA_BACSU / P25993 Carbamoyl phosphate synthase pyrimidine-specific small chain; Carbamoyl phosphate synthetase glutamine chain 2; EC 6.3.5.5 from Bacillus subtilis (strain 168) (see paper)
31% identity, 78% coverage of query (69.3 bits)
8hx9A / Q6L8Q5 Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae with chorismate (see paper)
32% identity, 96% coverage of query (68.2 bits)
7yc6A / Q58970 Crystal structure of d110p mutant of gatase subunit of methanocaldococcus jannaschii gmp synthetase
27% identity, 96% coverage of query (67.0 bits)
3r75B / Q396C7 Crystal structure of 2-amino-2-desoxyisochorismate synthase (adic) synthase phze from burkholderia lata 383 in complex with benzoate, pyruvate, glutamine and contaminating zn2+ (see paper)
30% identity, 92% coverage of query (61.6 bits)
1gpmA / P04079 Escherichia coli gmp synthetase complexed with amp and pyrophosphate (see paper)
21% identity, 97% coverage of query (48.9 bits)
GUAA_HUMAN / P49915 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Homo sapiens (Human) (see 2 papers)
P49915 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Homo sapiens (see paper)
22% identity, 96% coverage of query (47.4 bits)
2vxoB / P49915 Human gmp synthetase in complex with xmp (see paper)
23% identity, 96% coverage of query (46.6 bits)
2ywcA / Q5SI28 Crystal structure of gmp synthetase from thermus thermophilus in complex with xmp
24% identity, 96% coverage of query (45.4 bits)
5tw7F / B4RJH7 Crystal structure of a gmp synthase (glutamine-hydrolyzing) from neisseria gonorrhoeae
23% identity, 96% coverage of query (45.4 bits)
P20054 Multifunctional protein pyr1-3; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Dictyostelium discoideum (Social amoeba)
30% identity, 73% coverage of query (45.1 bits)
6w2jB / P31327 Cps1 bound to allosteric inhibitor h3b-374 (see paper)
27% identity, 74% coverage of query (43.5 bits)
6w2jA Cps1 bound to allosteric inhibitor h3b-374
27% identity, 74% coverage of query (43.5 bits)
6uelA / P31327 Cps1 bound to allosteric inhibitor h3b-193 (see paper)
27% identity, 74% coverage of query (43.5 bits)
5douD / P31327 Crystal structure of human carbamoyl phosphate synthetase i (cps1), ligand-bound form (see paper)
27% identity, 74% coverage of query (43.5 bits)
CPS1 / P31327 ammonia-dependent carbamoyl-phosphate synthase (EC 6.3.4.16) from Homo sapiens (see 4 papers)
CPSM_HUMAN / P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial; Carbamoyl-phosphate synthetase I; CPSase I; EC 6.3.4.16 from Homo sapiens (Human) (see 19 papers)
P31327 carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16) from Homo sapiens (see 10 papers)
27% identity, 74% coverage of query (43.5 bits)
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