Searching for up to 100 curated homologs for Pf6N2E2_1813 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1813 (329 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.5.29 / Q9WXR3 Oligopeptide ABC transporter, ATP-binding protein, component of Probable xylan oligosaccharide porter (Conners et al. 2005). Induced by cylan and xylose. Regulated by xylose-responsive regulator XylR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
51% identity, 90% coverage of query (309 bits)
TC 3.A.1.5.12 / Q9X0F3 TM1063, component of Probable rhamnose oligosaccharide porter. Induced by rhamnose (see paper)
50% identity, 95% coverage of query (299 bits)
TC 3.A.1.5.20 / P42065 AppF, component of 5-6 amino acyl oligopeptide transporter AppA-F from Bacillus subtilis (see 3 papers)
47% identity, 96% coverage of query (299 bits)
DppF / b3540 dipeptide ABC transporter ATP binding subunit DppF (EC 7.4.2.9) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
DppF / P37313 dipeptide ABC transporter ATP binding subunit DppF (EC 7.4.2.9) from Escherichia coli (strain K12) (see 2 papers)
DPPF_ECOLI / P37313 Dipeptide transport ATP-binding protein DppF; EC 7.4.2.9 from Escherichia coli (strain K12) (see 3 papers)
48% identity, 95% coverage of query (298 bits)
TC 3.A.1.5.27 / P45094 Dipeptide transport ATP-binding protein DppF, component of The glutathione uptake porter, DppBCDF with the glutathione binding protein, DppA (GbpA; HbpA). Takes up reduced (GSH) and oxidized (GSSG) but not bulky glutathione S conjugates or glutathione derivatives with C-terminal modifications from Haemophilus influenzae (see 2 papers)
49% identity, 88% coverage of query (297 bits)
OppF / b1247 murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppF (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
oppF / P77737 murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppF (EC 7.4.2.6) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.5.41 / P77737 Oligopeptide transport ATP-binding protein OppF, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (strain K12)
49% identity, 95% coverage of query (293 bits)
TC 3.A.1.5.39 / W0WLZ8 Dipeptide transport ATP-binding protein DppF, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
47% identity, 93% coverage of query (290 bits)
TC 3.A.1.5.37 / B1W1L8 Putative peptide ABC transporter ATP-binding protein, component of The ABC BldKA-E (SGR_2418-2414) oligopeptide transport system. It controls aerial mycelium formation on glucose media. Probably involved in extracellular peptide signalling (Akanuma et al. 2011). Probably orthologous to 3.A.1.5.35 from Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
48% identity, 90% coverage of query (289 bits)
DPPF_PSEAB / A0A0H2ZH52 Di/tripeptide transport ATP-binding protein DppF; EC 7.4.2.9 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
47% identity, 93% coverage of query (289 bits)
TC 3.A.1.5.1 / P08007 OppF aka STM1742, component of Oligopeptide porter (also takes up amino glycoside antibiotics such as kanamycin, streptomycin and neomycin as well as cell wall-derived peptides such as murein tripeptide). It transports substrate peptides of 2-5 amino acids with highest affinity for tripeptides. Also transports δ-aminolevulinic acid (ALA). [May be regulated by PTS Enzyme INtr-aspartokinase.] ATP-binding to OppDF may result in donation of peptide to OppBC and simultaneous release of OppA from Salmonella typhimurium (see 2 papers)
48% identity, 95% coverage of query (288 bits)
TC 3.A.1.5.15 / Q9X272 TM1750, component of Probable mannose/mannoside porter. Induced by beta-mannan (Conners et al., 2005). Regulated by mannose-responsive regulator manR (see paper)
48% identity, 91% coverage of query (285 bits)
Q5V9R8 ABC-type oligopeptide transporter (EC 7.4.2.6) from Vibrio fluvialis (see paper)
TC 3.A.1.5.22 / Q5V9R8 OppF, component of The peptide transporter OppA,B,C,D,F (influences biofilm formation; Lee et al., 2004). Similar to 3.A.1.5.1, OppA is similar to the Vibrio furnissii OppA that provides several functions: hemolysis, antibiotic resistance, and virulence from Vibrio fluvialis (see paper)
46% identity, 96% coverage of query (281 bits)
TC 3.A.1.5.36 / Q8CJS2 Putative peptide transport system ATP-binding subunit, component of Peptide transporter encoded adjacent to the putative transport system with TC#3.A.1.5.35 (Akanuma et al. 2011). Induced by exogenous S-adenosylmethionine (SAM) at a concentration of 2muM which also enhanced antibiotic production and inhibited morphological development (Park et al. 2005). SAM can be imported into cells. Mutants in the bldK genes confer resistance to the toxic tripeptide, bialaphos from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
45% identity, 94% coverage of query (277 bits)
Q73NS6 ABC-type dipeptide transporter (EC 7.4.2.9) from Treponema denticola (see paper)
44% identity, 90% coverage of query (265 bits)
DdpF / b1483 putative D,D-dipeptide ABC transporter ATP-binding subunit DdpF from Escherichia coli K-12 substr. MG1655 (see 2 papers)
DDPF_ECOLI / P77622 Probable D,D-dipeptide transport ATP-binding protein DdpF from Escherichia coli (strain K12) (see paper)
47% identity, 95% coverage of query (258 bits)
OPPF_BACSU / P24137 Oligopeptide transport ATP-binding protein OppF; Stage 0 sporulation protein KE from Bacillus subtilis (strain 168) (see paper)
47% identity, 74% coverage of query (241 bits)
TC 3.A.1.5.18 / O31310 OppF, component of The oligopeptide transporter OppA1-5, B1, C1, DF (functions with five binding proteins of differing induction properties and peptide specificities; OppA1-3 are chromosomally encoded; OppA4 and 5 are plasmid encoded.) from Borrelia burgdorferi (Lyme disease spirochete) (see 2 papers)
44% identity, 79% coverage of query (234 bits)
TC 3.A.1.5.12 / Q9X0F4 TM1064, component of Probable rhamnose oligosaccharide porter. Induced by rhamnose (see paper)
45% identity, 82% coverage of query (234 bits)
TC 3.A.1.5.2 / P26905 DppD aka DCIAD, component of Dipeptide porter. Also transports δ-aminolevulinic acid (ALA) and heme from Bacillus subtilis (see 2 papers)
43% identity, 91% coverage of query (233 bits)
TC 3.A.1.5.10 / P0A2V4 OppF, component of Oligopeptide porter (transports peptides of 4-35) amino acyl residues; di- and tripeptides are not transported; hydrophobic basic peptides are preferred). OppA determines the specificity of the system (Doeven et al., 2004). A large cavity in OppA binds proline-rich peptides preferentially (Berntsson et al., 2009). Two crystal structures of OppA with different nonapeptides show binding in different registers from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see 2 papers)
44% identity, 77% coverage of query (232 bits)
Q8ZQM4 ABC-type glutathione transporter (EC 7.4.2.10) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
48% identity, 75% coverage of query (225 bits)
TC 3.A.1.5.19 / Q2FZR4 OppF, component of The major oligopeptide uptake porter, Opp-3 (of four paralogues, this is the only one that mediates nitrogen nutrition from Staphylococcus aureus (strain NCTC 8325)
42% identity, 79% coverage of query (223 bits)
TC 3.A.1.5.29 / Q9WXR4 Oligopeptide ABC transporter, ATP-binding protein, component of Probable xylan oligosaccharide porter (Conners et al. 2005). Induced by cylan and xylose. Regulated by xylose-responsive regulator XylR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
41% identity, 95% coverage of query (223 bits)
TC 3.A.1.5.26 / P63395 Uncharacterized ABC transporter ATP-binding protein Rv1281c/MT1318, component of The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis from Mycobacterium tuberculosis (see 2 papers)
46% identity, 75% coverage of query (223 bits)
TC 3.A.1.5.4 / O30542 AccC, component of Agrocinopine (an opine)/Agrocin 84 (an antibiotic) porter from Agrobacterium radiobacter (see 3 papers)
42% identity, 97% coverage of query (223 bits)
TC 3.A.1.5.32 / F0TFS9 Oligopeptide ABC transporter ATP-binding protein, component of ABC α-galactoside uptake porter from Lactobacillus acidophilus (strain 30SC)
40% identity, 81% coverage of query (221 bits)
TC 3.A.1.5.15 / Q9X271 TM1749, component of Probable mannose/mannoside porter. Induced by beta-mannan (Conners et al., 2005). Regulated by mannose-responsive regulator manR (see paper)
41% identity, 90% coverage of query (221 bits)
TC 3.A.1.5.20 / P42064 AppD, component of 5-6 amino acyl oligopeptide transporter AppA-F from Bacillus subtilis (see 2 papers)
40% identity, 90% coverage of query (220 bits)
TC 3.A.1.5.37 / B1W1L9 Putative peptide ABC transporter ATP-binding protein, component of The ABC BldKA-E (SGR_2418-2414) oligopeptide transport system. It controls aerial mycelium formation on glucose media. Probably involved in extracellular peptide signalling (Akanuma et al. 2011). Probably orthologous to 3.A.1.5.35 from Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
39% identity, 94% coverage of query (219 bits)
TC 3.A.1.5.36 / Q93IU0 BldKD, putative ABC transporter intracellular ATPase subunit, component of Peptide transporter encoded adjacent to the putative transport system with TC#3.A.1.5.35 (Akanuma et al. 2011). Induced by exogenous S-adenosylmethionine (SAM) at a concentration of 2muM which also enhanced antibiotic production and inhibited morphological development (Park et al. 2005). SAM can be imported into cells. Mutants in the bldK genes confer resistance to the toxic tripeptide, bialaphos from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
42% identity, 87% coverage of query (219 bits)
GsiA / b0829 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
gsiA / P75796 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli (strain K12) (see 3 papers)
GSIA_ECOLI / P75796 Glutathione import ATP-binding protein GsiA; EC 7.4.2.10 from Escherichia coli (strain K12) (see paper)
P75796 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75796 Hypothetical ABC transporter ATP-binding protein yliA, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 4 papers)
48% identity, 75% coverage of query (219 bits)
A0A150QXP6 5-(carboxyamino)imidazole ribonucleotide mutase (EC 5.4.99.18) from Bacillus anthracis (see paper)
43% identity, 90% coverage of query (218 bits)
TC 3.A.1.5.1 / P04285 OppD aka STM1743, component of Oligopeptide porter (also takes up amino glycoside antibiotics such as kanamycin, streptomycin and neomycin as well as cell wall-derived peptides such as murein tripeptide). It transports substrate peptides of 2-5 amino acids with highest affinity for tripeptides. Also transports δ-aminolevulinic acid (ALA). [May be regulated by PTS Enzyme INtr-aspartokinase.] ATP-binding to OppDF may result in donation of peptide to OppBC and simultaneous release of OppA from Salmonella typhimurium (see 3 papers)
41% identity, 91% coverage of query (215 bits)
OppD / b1246 murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppD (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
oppD / P76027 murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppD (EC 7.4.2.6) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.5.41 / P76027 Oligopeptide transport ATP-binding protein OppD, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (strain K12)
oppD oligopeptide ABC transporter, ATP-binding protein OppD from Escherichia coli K12 (see paper)
41% identity, 92% coverage of query (213 bits)
SM_b21644 ABC transporter for D-Raffinose, ATPase component from Sinorhizobium meliloti 1021
46% identity, 77% coverage of query (210 bits)
DPPD_CALS4 / Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
38% identity, 96% coverage of query (185 bits)
4fwiB / Q8RDH4 Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
39% identity, 96% coverage of query (184 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
41% identity, 76% coverage of query (166 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
41% identity, 76% coverage of query (164 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
41% identity, 76% coverage of query (164 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
41% identity, 76% coverage of query (164 bits)
SapD / b1291 putrescine ABC exporter ATP binding protein SapD (EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
SapD / P0AAH4 putrescine ABC exporter ATP binding protein SapD (EC 7.6.2.16) from Escherichia coli (strain K12) (see 5 papers)
SAPD_ECOLI / P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see 2 papers)
34% identity, 88% coverage of query (150 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
36% identity, 71% coverage of query (139 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
39% identity, 72% coverage of query (136 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
37% identity, 71% coverage of query (133 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
37% identity, 71% coverage of query (133 bits)
2olkA Abc protein artp in complex with adp-beta-s
37% identity, 71% coverage of query (133 bits)
2oljA Abc protein artp in complex with adp/mg2+
37% identity, 71% coverage of query (133 bits)
7ahhC Opua inhibited inward-facing, sbd docked
33% identity, 71% coverage of query (125 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
33% identity, 71% coverage of query (125 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
31% identity, 75% coverage of query (125 bits)
2pmkA Crystal structures of an isolated abc-atpase in complex with tnp-adp
33% identity, 71% coverage of query (120 bits)
2ff7A The abc-atpase of the abc-transporter hlyb in the adp bound state
33% identity, 71% coverage of query (120 bits)
3b5jA Crystal structures of the s504a mutant of an isolated abc-atpase in complex with tnp-adp
33% identity, 71% coverage of query (119 bits)
7sgrE / Q8FDZ8 Structure of hemolysin a secretion system hlyb/d complex (see paper)
33% identity, 71% coverage of query (118 bits)
8dckA Structure of hemolysin a secretion system hlyb/d complex, atp-bound
33% identity, 71% coverage of query (117 bits)
1g291 / Q9YGA6 Malk (see paper)
30% identity, 72% coverage of query (117 bits)
1xefA Crystal structure of the atp/mg2+ bound composite dimer of hlyb-nbd
33% identity, 71% coverage of query (117 bits)
8g4cB / O34697 Bceabs atpgs high res tm (see paper)
32% identity, 71% coverage of query (115 bits)
5ws4A / A0A0D8G707 Crystal structure of tripartite-type abc transporter macb from acinetobacter baumannii (see paper)
33% identity, 71% coverage of query (113 bits)
7tchB Bceab e169q variant atp-bound conformation
31% identity, 71% coverage of query (113 bits)
Build an alignment for Pf6N2E2_1813 and 61 homologs with ≥ 30% identity
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1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
29% identity, 75% coverage of query (111 bits)
7o9wA Encequidar-bound human p-glycoprotein in complex with uic2-fab
33% identity, 70% coverage of query (108 bits)
7a6fA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and zosuquidar
33% identity, 70% coverage of query (108 bits)
7a6eA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and tariquidar
33% identity, 70% coverage of query (108 bits)
7a6cA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and elacridar
33% identity, 70% coverage of query (108 bits)
7a69A Nanodisc reconstituted human abcb1 in complex with mrk16 fab and vincristine
33% identity, 70% coverage of query (108 bits)
6qexA / P08183 Nanodisc reconstituted human abcb1 in complex with uic2 fab and taxol (see paper)
33% identity, 70% coverage of query (108 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
33% identity, 75% coverage of query (107 bits)
6c0vA Molecular structure of human p-glycoprotein in the atp-bound, outward- facing conformation
32% identity, 70% coverage of query (106 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
31% identity, 73% coverage of query (106 bits)
7t55A / A3DCU1 Cryo-em structure of pcat1 in the inward-facing wide conformation under atp turnover condition (see paper)
32% identity, 74% coverage of query (106 bits)
4s0fA Crystal structure of the peptidase-containing abc transporter pcat1 e648q mutant complexed with atpgs in an occluded conformation
31% identity, 74% coverage of query (105 bits)
7otgA Structure of abcb1/p-glycoprotein in the presence of the cftr potentiator ivacaftor
33% identity, 70% coverage of query (103 bits)
6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
32% identity, 75% coverage of query (103 bits)
4xwkA P-glycoprotein co-crystallized with bde-100
33% identity, 70% coverage of query (103 bits)
4q9iA P-glycoprotein cocrystallised with qz-ala
33% identity, 70% coverage of query (103 bits)
4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
33% identity, 70% coverage of query (103 bits)
3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
32% identity, 75% coverage of query (103 bits)
3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
32% identity, 75% coverage of query (103 bits)
6qeeA Nanodisc reconstituted human-mouse chimeric abcb1 (abcb1hm)-eq mutant in complex with uic2 fab and zosuquidar.
33% identity, 70% coverage of query (102 bits)
5koyA Mouse pgp 34 linker deleted bound with atp
33% identity, 70% coverage of query (102 bits)
7zkaA Abcb1 v978c mutant (mabcb1) in the outward facing state bound to aac
33% identity, 70% coverage of query (99.4 bits)
7zk6A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to 2 molecules of aac
33% identity, 70% coverage of query (99.4 bits)
7zk5A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to aac
33% identity, 70% coverage of query (99.4 bits)
7zk4A The abcb1 l335c mutant (mabcb1) in the outward facing state
33% identity, 70% coverage of query (99.4 bits)
6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
32% identity, 70% coverage of query (98.2 bits)
TAP1_RAT / P36370 Antigen peptide transporter 1; APT1; ATP-binding cassette sub-family B member 2; Peptide transporter TAP1; EC 7.4.2.14 from Rattus norvegicus (Rat) (see 2 papers)
P36370 ABC-type antigen peptide transporter (subunit 2/2) (EC 7.4.2.14) from Rattus norvegicus (see 6 papers)
32% identity, 71% coverage of query (97.4 bits)
ABCB7_ORYLA / H2LNR5 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial from Oryzias latipes (Japanese rice fish) (Japanese killifish) (see paper)
28% identity, 71% coverage of query (96.3 bits)
ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
33% identity, 72% coverage of query (91.7 bits)
7mitE / Q63563 Vascular katp channel: kir6.1 sur2b propeller-like conformation 1 (see paper)
30% identity, 74% coverage of query (91.3 bits)
MsbA / b0914 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli K-12 substr. MG1655 (see 54 papers)
msbA / P60752 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli (strain K12) (see 57 papers)
MSBA_ECOLI / P60752 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; Lipid flippase; EC 7.5.2.6 from Escherichia coli (strain K12) (see 17 papers)
P60752 ABC-type lipid A-core oligosaccharide transporter (EC 7.5.2.6); P-type phospholipid transporter (EC 7.6.2.1) from Escherichia coli (see 13 papers)
TC 3.A.1.106.1 / P60752 Phospholipid, LPS, lipid A and drug exporter, MsbA, which flips the substrate from the inner leaflet of the cytoplasmic membrane to the outer leaflet (Eckford and Sharom, 2010). MsbA also confers drug resistance to azidopine, daunomycin, vinblastine, Hoechst 33342 and ethidium (Reuter et al., 2003). Four x-ray structures, trapped in different conformations, two with and two without nucleotide, have been solved (Ward et al., 2007). They suggest an alternating accessibility mode of transport with major conformational changes from Escherichia coli (see 11 papers)
msbA / MB|P60752 lipid A export ATP-binding/permease protein msbA; EC 3.6.3.- from Escherichia coli K12 (see 24 papers)
31% identity, 70% coverage of query (90.1 bits)
7ph3A / P60752 Amp-pnp bound nanodisc reconstituted msba with nanobodies, spin- labeled at position a60c (see paper)
31% identity, 70% coverage of query (89.7 bits)
7ph2A Nanodisc reconstituted msba in complex with nanobodies, spin-labeled at position a60c
31% identity, 70% coverage of query (89.7 bits)
7mewA E. Coli msba in complex with g247
31% identity, 70% coverage of query (89.7 bits)
6bppA E. Coli msba in complex with lps and inhibitor g092
31% identity, 70% coverage of query (89.7 bits)
6bplA E. Coli msba in complex with lps and inhibitor g907
31% identity, 70% coverage of query (89.7 bits)
P59852 Lactococcin-G-processing and transport ATP-binding protein LagD; EC 3.4.22.-; EC 7.-.-.- from Lactococcus lactis subsp. lactis (Streptococcus lactis)
30% identity, 73% coverage of query (89.7 bits)
8dmmA Structure of the vanadate-trapped msba bound to kdl
31% identity, 70% coverage of query (89.7 bits)
7bcwA Structure of msba in salipro with adp vanadate
31% identity, 70% coverage of query (89.7 bits)
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Lawrence Berkeley National Laboratory