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Searching for up to 100 curated homologs for Pf6N2E2_227 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_227 (548 a.a.)

Found high-coverage hits (≥70%) to 11 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

MhpA / b0347 3-(3-hydroxyphenyl)propanoate hydroxylase (EC 1.14.13.127) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
mhpA / P77397 3-(3-hydroxyphenyl)propanoate hydroxylase (EC 1.14.13.127) from Escherichia coli (strain K12) (see 4 papers)
MHPA_ECOLI / P77397 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase; 3-HCI hydroxylase; 3-HPP hydroxylase; EC 1.14.13.127 from Escherichia coli (strain K12) (see paper)
    41% identity, 92% coverage of query (375 bits)

stiL / CAD19095.1 cytochrome P450 dependent monooxygenase from Stigmatella aurantiaca (see paper)
    34% identity, 95% coverage of query (285 bits)

rif19 / Q9AE02 rifamycin ring hydroxylase from Amycolatopsis mediterranei (see 4 papers)
    34% identity, 79% coverage of query (195 bits)

Build an alignment

Build an alignment for Pf6N2E2_227 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Cgl1158 / Q8NR94 resorcinol 4-hydroxylase (NADPH) (EC 1.14.13.219) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
RES4H_CORGL / Q8NR94 NADPH-dependent resorcinol 4-hydroxylase; Resorcinol hydroxylase; EC 1.14.13.219 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
    29% identity, 92% coverage of query (187 bits)

cxm19 / A0A0F7VPM8 chaxamycin ring hydroxylase from Streptomyces leeuwenhoekii (see 3 papers)
    32% identity, 92% coverage of query (180 bits)

tsdB / Q0SFL5 resorcinol 4-hydroxylase (NADH) (EC 1.14.13.220) from Rhodococcus jostii (strain RHA1) (see 2 papers)
TSDB_RHOJR / Q0SFL5 Probable NADH-specific resorcinol 4-hydroxylase; EC 1.14.13.220 from Rhodococcus jostii (strain RHA1) (see paper)
    28% identity, 98% coverage of query (171 bits)

stvO4 / A0A286SC03 streptovaricin ring hydroxylase from Streptomyces spectabilis (see 2 papers)
    33% identity, 81% coverage of query (165 bits)

mtmOII / Q194R1 MtmOII from Streptomyces argillaceus (see 3 papers)
    28% identity, 92% coverage of query (138 bits)

TERD_ASPTN / Q0D1P2 FAD-dependent monooxygenase terD; Terrein biosynthesis cluster protein terD; EC 1.-.-.- from Aspergillus terreus (strain NIH 2624 / FGSC A1156) (see 13 papers)
    28% identity, 72% coverage of query (117 bits)

7yj0D Structural basis of oxepinone formation by a flavin-monooxygenase vibo
    27% identity, 95% coverage of query (101 bits)

AZPA4_ASPTN / Q0CRP9 FAD-dependent monooxygenase ATEG_03635; Azasperpyranone A biosynthesis cluster A protein ATEG_03635; EC 1.-.-.- from Aspergillus terreus (strain NIH 2624 / FGSC A1156) (see 2 papers)
    27% identity, 85% coverage of query (89.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory