Searching for up to 100 curated homologs for Pf6N2E2_2725 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_2725 (310 a.a.)
Found high-coverage hits (≥70%) to 23 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Sama_3039 Phosphoglycerate dehydrogenase (EC 1.1.1.95) from Shewanella amazonensis SB2B
34% identity, 100% coverage of query (175 bits)
ddh / Q2VEQ7 (D)-2-hydroxyacid dehydrogenase (NADP+) monomer (EC 1.1.1.272) from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (see paper)
DDH_HALMT / Q2VEQ7 D-2-hydroxyacid dehydrogenase; D2-HDH; D-specific 2-hydroxyacid dehydrogenase; EC 1.1.1.- from Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei) (see paper)
Q2VEQ7 D-2-hydroxyacid dehydrogenase (NADP+) (EC 1.1.1.272) from Haloferax mediterranei (see 3 papers)
5mh5A / Q2VEQ7 D-2-hydroxyacid dehydrogenases (d2-hdh) from haloferax mediterranei in complex with 2-keto-hexanoic acid and NADP+ (1.4 a resolution)
31% identity, 84% coverage of query (108 bits)
5mh6A D-2-hydroxyacid dehydrogenases (d2-hdh) from haloferax mediterranei in complex with 2-ketohexanoic acid and NAD+ (1.35 a resolution)
31% identity, 84% coverage of query (108 bits)
5mhaB D-2-hydroxyacid dehydrogenases (d2-hdh) from haloferax mediterranei in complex with a mixture of 2-ketohexanoic acid and 2-hydroxyhexanoic acid, and NADPH (1.57 a resolution)
31% identity, 84% coverage of query (108 bits)
5mhaA D-2-hydroxyacid dehydrogenases (d2-hdh) from haloferax mediterranei in complex with a mixture of 2-ketohexanoic acid and 2-hydroxyhexanoic acid, and NADPH (1.57 a resolution)
31% identity, 84% coverage of query (108 bits)
5vg6B / A7IIH0 Crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase from xanthobacter autotrophicus py2 in complex with NADPH and mes.
32% identity, 78% coverage of query (106 bits)
Build an alignment for Pf6N2E2_2725 and 6 homologs with ≥ 30% identity
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7jqhA / A0A140NAE3 Structure of wild type glyoxylate/hydroxypyruvate reductase a from escherichia coli in complex with phosphate and NADP+
28% identity, 78% coverage of query (103 bits)
7jqiA Structure of wild type glyoxylate/hydroxypyruvate reductase a from escherichia coli in complex with alpha-ketoglutarate and NADP+
28% identity, 78% coverage of query (103 bits)
6p35A 2.5 angstrom structure of wild type glyoxylate/hydroxypyruvate reductase a from escherichia coli in complex with 2-keto arginine and NADP
28% identity, 78% coverage of query (103 bits)
GhrA / b1033 glyoxylate/hydroxypyruvate reductase A (EC 1.1.1.79) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ghrA / P75913 glyoxylate/hydroxypyruvate reductase A (EC 1.1.1.79) from Escherichia coli (strain K12) (see 4 papers)
GHRA_ECOLI / P75913 Glyoxylate/hydroxypyruvate reductase A; 2-ketoacid reductase; EC 1.1.1.79; EC 1.1.1.81 from Escherichia coli (strain K12) (see paper)
28% identity, 78% coverage of query (102 bits)
4zqbB / Q3IWN8 Crystal structure of NADP-dependent dehydrogenase from rhodobactersphaeroides in complex with NADP and sulfate
27% identity, 94% coverage of query (92.8 bits)
O58256 phosphoglycerate dehydrogenase (EC 1.1.1.95) from Pyrococcus horikoshii (see paper)
29% identity, 71% coverage of query (87.4 bits)
TkrA / b3553 glyoxylate reductase (EC 1.1.1.79; EC 1.1.1.215) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ghrB / P37666 glyoxylate reductase (EC 1.1.1.79; EC 1.1.1.215) from Escherichia coli (strain K12) (see 4 papers)
GHRB_ECOLI / P37666 Glyoxylate/hydroxypyruvate reductase B; 2-ketoaldonate reductase; 2-ketogluconate reductase; 2KR; EC 1.1.1.79; EC 1.1.1.81; EC 1.1.1.215 from Escherichia coli (strain K12) (see 2 papers)
ghrB / GB|AAC76577.2 glyoxylate/hydroxypyruvate reductase B; EC 1.1.1.215; EC 1.1.1.79; EC 1.1.1.81 from Escherichia coli K12 (see 6 papers)
28% identity, 72% coverage of query (72.0 bits)
1wwkA / O50095 Crystal structure of phosphoglycerate dehydrogenase from pyrococcus horikoshii ot3
28% identity, 90% coverage of query (72.0 bits)
HPR3 / Q9LE33 glyoxylate reductase (NADP+) (EC 1.1.1.79; EC 1.1.1.81) from Arabidopsis thaliana (see 8 papers)
HPR3_ARATH / Q9LE33 Glyoxylate/hydroxypyruvate reductase HPR3; NAD(P)H-dependent hydroxypyruvate reductase 3; AtHPR3; HPR 3; EC 1.1.1.79; EC 1.1.1.81 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9LE33 hydroxyphenylpyruvate reductase (EC 1.1.1.237); hydroxypyruvate reductase (EC 1.1.1.81) from Arabidopsis thaliana (see 3 papers)
27% identity, 78% coverage of query (70.9 bits)
hprA / Q59516 hydroxypyruvate reductase subunit (EC 1.1.1.81) from Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) (see 2 papers)
28% identity, 72% coverage of query (70.1 bits)
A0A178WMD4 hydroxyphenylpyruvate reductase (EC 1.1.1.237); glyoxylate reductase (NADP+) (EC 1.1.1.79); hydroxypyruvate reductase (EC 1.1.1.81) from Arabidopsis thaliana (see 2 papers)
26% identity, 78% coverage of query (68.6 bits)
2KGR_GLUOX / Q5FTU6 2-ketogluconate reductase; 2KGR; Gluconate 2-dehydrogenase; EC 1.1.1.215 from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
Q5FTU6 gluconate 2-dehydrogenase (EC 1.1.1.215) from Gluconobacter oxydans (see 2 papers)
26% identity, 73% coverage of query (66.2 bits)
2gsdA / O08375 NAD-dependent formate dehydrogenase from bacterium moraxella sp.C2 in complex with NAD and azide (see paper)
26% identity, 82% coverage of query (57.4 bits)
5z21B / Q8RG11 The ternary structure of d-lactate dehydrogenase from fusobacterium nucleatum with nadh and oxamate (see paper)
23% identity, 76% coverage of query (49.7 bits)
4e5mA Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP
26% identity, 79% coverage of query (48.5 bits)
4e5pA / O69054 Thermostable phosphite dehydrogenase a176r variant in complex with nad (see paper)
26% identity, 79% coverage of query (48.1 bits)
2eklA / Q972A9 Structure of st1218 protein from sulfolobus tokodaii
21% identity, 88% coverage of query (46.6 bits)
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