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Searching for up to 100 curated homologs for Pf6N2E2_2923 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_2923 (307 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

Removed hits that are identical to the query, leaving 16

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.4.8 / P21627 High-affinity branched-chain amino acid transport system permease protein BraD, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    85% identity, 100% coverage of query (491 bits)

LivH / b3457 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
LivH / P0AEX7 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH (EC 7.4.2.2) from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.4.1 / P0AEX7 High-affinity branched-chain amino acid transport system permease protein LivH aka B3457, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 6 papers)
livH high-affinity branched-chain amino acid ABC transporter, permease protein LivH from Escherichia coli K12 (see 6 papers)
    67% identity, 98% coverage of query (394 bits)

AZOBR_RS08235 L-proline and D-alanine ABC transporter, permease component 1 from Azospirillum brasilense Sp245
    57% identity, 98% coverage of query (348 bits)

braD / CAB75549.1 integral membrane protein from Rhizobium leguminosarum bv. viciae (see 2 papers)
    51% identity, 98% coverage of query (293 bits)

Ac3H11_1695 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, permease component 1 from Acidovorax sp. GW101-3H11
    45% identity, 98% coverage of query (241 bits)

HSERO_RS00885 L-proline ABC transporter, permease component 1 from Herbaspirillum seropedicae SmR1
    43% identity, 98% coverage of query (221 bits)

TC 3.A.1.4.10 / Q8DQI0 ABC transporter membrane-spanning permease-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    41% identity, 97% coverage of query (211 bits)

TC 3.A.1.4.3 / Q8VM85 BraD aka Bra2D, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae) (see paper)
    31% identity, 94% coverage of query (150 bits)

TC 3.A.1.4.2 / P74318 NatD aka LivH aka SLR0949, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE (see paper)
    30% identity, 94% coverage of query (109 bits)

TC 3.A.1.4.5 / Q8NRW0 UrtA, component of The high affinity urea/thiourea/hydroxyurea porter from Corynebacterium glutamicum (see paper)
    30% identity, 94% coverage of query (107 bits)

Build an alignment

Build an alignment for Pf6N2E2_2923 and 10 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 3.A.1.4.9 / Q0S718 ABC amino acid transporter, permease component, component of Uptake transporter, CamABCD of cholate (steroid) metabolites, 1β(2'-propanoate)-3aα-H-4α(3"(R)-hydroxy-3"-propanoate)-7aβ-methylhexahydro-5-indanone and a desaturated analog from Rhodococcus sp. (strain RHA1)
    29% identity, 94% coverage of query (99.0 bits)

TC 3.A.1.4.6 / Q8YXD0 NatD, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB) (see paper)
    28% identity, 94% coverage of query (98.2 bits)

TC 3.A.1.4.11 / Q6N8W0 Branched-chain amino acid transport system permease protein, component of The phenylpropeneoid uptake porter, CouPSTW from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
    31% identity, 74% coverage of query (97.8 bits)

PGA1_c12660 D-lactate transporter, permease component 2 from Phaeobacter inhibens BS107
    28% identity, 96% coverage of query (75.5 bits)

TC 3.A.1.4.7 / Q92TN1 ABC transporter, permease, component of The protocatechuate (3,4-dihydroxybenzoate) uptake porter, PcaMNVWX from Rhizobium meliloti (strain 1021)
    28% identity, 96% coverage of query (59.3 bits)

TC 3.A.1.4.11 / Q6N8W1 Putative branched-chain amino acid transport system ATP-binding protein, component of The phenylpropeneoid uptake porter, CouPSTW from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
    26% identity, 95% coverage of query (50.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory