Searching for up to 100 curated homologs for Pf6N2E2_3580 Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) (378 a.a.)
Found high-coverage hits (≥70%) to 39 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
AABP_PSEAE / Q9HUQ0 Amino acid binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
79% identity, 99% coverage of query (597 bits)
AZOBR_RS08260 L-proline and D-alanine ABC transporter, substrate-binding component from Azospirillum brasilense Sp245
50% identity, 93% coverage of query (339 bits)
3ip5A / Q7CX36 Structure of atu2422-gaba receptor in complex with alanine (see paper)
52% identity, 92% coverage of query (335 bits)
3ip9A Structure of atu2422-gaba receptor in complex with gaba
52% identity, 92% coverage of query (335 bits)
3ip7A Structure of atu2422-gaba receptor in complex with valine
52% identity, 92% coverage of query (335 bits)
3ip6A Structure of atu2422-gaba receptor in complex with proline
52% identity, 92% coverage of query (335 bits)
3ipcA Structure of atu2422-gaba f77a mutant receptor in complex with leucine
52% identity, 92% coverage of query (332 bits)
TC 3.A.1.4.3 / Q9L3M3 BraC, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae) (see 2 papers)
braC / CAB75553.1 periplasmic binding protein from Rhizobium leguminosarum bv. viciae (see 2 papers)
50% identity, 96% coverage of query (329 bits)
BRAC_PSEAE / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; LIVAT-BP; Leu/Ile/Val/Thr/Ala-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
TC 3.A.1.4.8 / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
43% identity, 95% coverage of query (284 bits)
LivJ / b3460 branched chain amino acid/phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
LivJ / P0AD96 branched chain amino acid/phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli (strain K12) (see 12 papers)
TC 3.A.1.4.1 / P0AD96 Leu/Ile/Val-binding protein LivJ aka B3460 aka LIV-BP, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 9 papers)
41% identity, 96% coverage of query (275 bits)
Pf6N2E2_2921 ABC transporter for L-leucine/L-phenylalanine/D-alanine, substrate-binding component LivK from Pseudomonas fluorescens FW300-N2E2
41% identity, 94% coverage of query (274 bits)
1z16A / P0AD96 Crystal structure analysis of periplasmic leu/ile/val-binding protein with bound leucine (see paper)
42% identity, 90% coverage of query (270 bits)
1z18A Crystal structure analysis of periplasmic leu/ile/val-binding protein with bound valine
42% identity, 90% coverage of query (270 bits)
1z17A Crystal structure analysis of periplasmic leu/ile/val-binding protein with bound ligand isoleucine
42% identity, 90% coverage of query (270 bits)
HrbC / b3458 L-leucine/L-phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 17 papers)
livK / P04816 L-leucine/L-phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli (strain K12) (see 16 papers)
TC 3.A.1.4.1 / P04816 Livk aka B3458, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 9 papers)
livK leucine-specific-binding protein LivK from Escherichia coli K12 (see 9 papers)
41% identity, 96% coverage of query (268 bits)
1usiA / P04816 L-leucine-binding protein with phenylalanine bound (see paper)
41% identity, 90% coverage of query (265 bits)
1uskA L-leucine-binding protein with leucine bound
41% identity, 90% coverage of query (265 bits)
4n0qB / Q8YEE8 Crystal structure of an abc transporter, substrate-binding protein from brucella melitensis 16m in complex with l-leucine using a crystal grown in a crystal former (microlytic)
43% identity, 91% coverage of query (264 bits)
LIVB3_RHIJ3 / Q1MDE9 Leu/Ile/Val-binding protein BraC3 from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
42% identity, 94% coverage of query (254 bits)
Ac3H11_2396 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, substrate-binding component from Acidovorax sp. GW101-3H11
34% identity, 92% coverage of query (182 bits)
HSERO_RS00870 L-proline ABC transporter, substrate-binding component from Herbaspirillum seropedicae SmR1
35% identity, 94% coverage of query (162 bits)
TC 3.A.1.4.10 / Q8DQI1 ABC transporter substrate-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
31% identity, 85% coverage of query (119 bits)
4gnrA / J9PBT7 1.0 angstrom resolution crystal structure of the branched-chain amino acid transporter substrate binding protein livj from streptococcus pneumoniae str. Canada mdr_19a in complex with isoleucine
31% identity, 85% coverage of query (119 bits)
Build an alignment for Pf6N2E2_3580 and 23 homologs with ≥ 30% identity
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4q6bA Crystal structure of abc transporter substrate-binding protein fromdesulfitobacterium hafniense complex with leu
28% identity, 92% coverage of query (118 bits)
4mlcA / B8FZ96 Abc transporter substrate-binding protein fromdesulfitobacterium hafniense
28% identity, 92% coverage of query (117 bits)
3td9A / Q9X0L9 Crystal structure of a leucine binding protein livk (tm1135) from thermotoga maritima msb8 at 1.90 a resolution
30% identity, 81% coverage of query (105 bits)
4nqrA / Q3MFZ5 The crystal structure of a solute-binding protein (n280d mutant) from anabaena variabilis atcc 29413 in complex with alanine
25% identity, 90% coverage of query (81.3 bits)
4rdcA The crystal structure of a solute-binding protein (n280d mutant) from anabaena variabilis atcc 29413 in complex with proline
25% identity, 90% coverage of query (81.3 bits)
4qymA The crystal structure of a solute-binding protein (n280d mutant) from anabaena variabilis atcc 29413 in complex with methionine
25% identity, 90% coverage of query (81.3 bits)
4otzA The crystal structure of a solute-binding protein (n280d mutant) from anabaena variabilis atcc 29413 in complex with cystein
25% identity, 90% coverage of query (81.3 bits)
4og2A The crystal structure of a solute-binding protein (n280d mutant) from anabaena variabilis atcc 29413 in complex with leucine
25% identity, 90% coverage of query (81.3 bits)
4oatA The crystal structure of a solute-binding protein (n280d mutant) from anabaena variabilis atcc 29413 in complex with isoleucine.
25% identity, 90% coverage of query (81.3 bits)
4nv3A The crystal structure of a solute-binding protein (n280d mutant) from anabaena variabilis atcc 29413 in complex with valine.
25% identity, 90% coverage of query (81.3 bits)
4rv5A The crystal structure of a solute-binding protein from anabaena variabilis atcc 29413 in complex with pyruvic acid
25% identity, 90% coverage of query (79.7 bits)
4obbA The crystal structure of a solute-binding protein from anabaena variabilis atcc 29413 in complex with (3s)-3-methyl-2-oxopentanoic acid.
25% identity, 90% coverage of query (79.7 bits)
fmdD / CAA75186.1 amide-urea binding protein from Methylophilus methylotrophus (see paper)
24% identity, 73% coverage of query (58.5 bits)
TC 3.A.1.4.7 / Q92TN0 ABC transporter, periplasmic solute-binding protein, component of The protocatechuate (3,4-dihydroxybenzoate) uptake porter, PcaMNVWX from Rhizobium meliloti (strain 1021)
28% identity, 73% coverage of query (58.5 bits)
4eygB / Q13AR6 Crystal structure of solute binding protein of abc transporter from rhodopseudomonas palustris bisb5 in complex with vanillic acid (see paper)
25% identity, 73% coverage of query (47.0 bits)
4zpjA / D1C6A8 Abc transporter substrate-binding protein from sphaerobacter thermophilus
25% identity, 72% coverage of query (46.6 bits)
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Lawrence Berkeley National Laboratory