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Searching for up to 100 curated homologs for Pf6N2E2_4516 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_4516 (306 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PotH / b0856 putrescine ABC transporter membrane subunit PotH (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
PotH / P31135 putrescine ABC transporter membrane subunit PotH (EC 7.6.2.11) from Escherichia coli (strain K12) (see paper)
POTH_ECOLI / P31135 Putrescine transport system permease protein PotH from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.11.2 / P31135 PotH aka B0856, component of Putrescine porter from Escherichia coli (see 5 papers)
potH putrescine transport system permease protein PotH from Escherichia coli K12 (see 5 papers)
    60% identity, 93% coverage of query (343 bits)

PotB / b1125 spermidine preferential ABC transporter membrane subunit PotB (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotB / P0AFK4 spermidine preferential ABC transporter membrane subunit PotB (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.1 / P0AFK4 Spermidine/putrescine transport system permease protein PotB aka B1125, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 5 papers)
potB spermidine/putrescine ABC transporter, permease protein PotB from Escherichia coli K12 (see 5 papers)
    40% identity, 89% coverage of query (193 bits)

TC 3.A.1.11.3 / Q44382 MotC, component of Mannopine porter from Agrobacterium tumefaciens (see paper)
    34% identity, 71% coverage of query (145 bits)

TC 3.A.1.11.4 / O70110 ChtI aka ChtJ, component of Chrysopine porter (see paper)
    30% identity, 88% coverage of query (133 bits)

A0A0K2E5X6 ABC-type polyamine transporter (subunit 3/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
    31% identity, 87% coverage of query (126 bits)

Build an alignment

Build an alignment for Pf6N2E2_4516 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.11.7 / Q97Q43 Spermidine/putrescine ABC transporter, permease protein, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
    28% identity, 93% coverage of query (121 bits)

YdcU / b1442 putative ABC transporter membrane subunit YdcU from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ydcU / P77156 putative ABC transporter membrane subunit YdcU from Escherichia coli (strain K12) (see 2 papers)
YDCU_ECOLI / P77156 Inner membrane ABC transporter permease protein YdcU from Escherichia coli (strain K12) (see 2 papers)
    30% identity, 75% coverage of query (106 bits)

TC 3.A.1.20.1 / O54371 BitE, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
    29% identity, 71% coverage of query (78.2 bits)

GGTC_SYNY3 / Q55472 Osmoprotective compounds uptake permease protein GgtC from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
TC 3.A.1.1.32 / Q55472 Membrane bound sugar transport protein, component of The glucosylglycerol uptake transporter (functions in osmoprotection and also transports sucrose and trehalose (Mikkat and Hagemann, 2000) (most similar to 3.A.1.1.8) from Synechocystis sp. (strain PCC 6803) (see paper)
    25% identity, 85% coverage of query (66.6 bits)

TC 3.A.1.1.25 / Q72H67 Maltose transport system permease protein malF aka TT_C1628, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    27% identity, 87% coverage of query (65.5 bits)

CysU / b2424 sulfate/thiosulfate ABC transporter inner membrane subunit CysU (EC 7.3.2.3; EC 7.3.2.5) from Escherichia coli K-12 substr. MG1655 (see paper)
CysU / P16701 sulfate/thiosulfate ABC transporter inner membrane subunit CysU (EC 7.3.2.3; EC 7.3.2.5) from Escherichia coli (strain K12) (see paper)
CYST_ECOLI / P16701 Sulfate transport system permease protein CysT from Escherichia coli (strain K12) (see paper)
TC 3.A.1.6.1 / P16701 CysT aka CysU aka B2424, component of Sulfate/thiosulfate porter from Escherichia coli (see 6 papers)
    24% identity, 75% coverage of query (58.2 bits)

WTPB_ARCFU / O30143 Molybdate/tungstate transport system permease protein WtpB from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
TC 3.A.1.6.8 / O30143 Molybdate/tungstate transport system permease protein WtpB, component of Molybdate/tungstate transport system, ModABC (WtpABC) (ModA binds to ModBC with high affinity (0.11%u03BCM) and dissociates slowly; the complex is destabilized by nucleotide and substrate binding from Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
    25% identity, 77% coverage of query (55.8 bits)

TC 3.A.1.1.44 / Q9KZ07 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    22% identity, 95% coverage of query (52.4 bits)

TC 3.A.1.11.3 / Q44381 MotD, component of Mannopine porter from Agrobacterium tumefaciens (see paper)
    23% identity, 87% coverage of query (49.3 bits)

TC 3.A.1.1.6 / Q48396 CymF, component of Cyclodextrin porter from Klebsiella oxytoca (see paper)
    26% identity, 75% coverage of query (48.1 bits)

SMc02872 ABC transporter for N-Acetyl-D-glucosamine, permease protein 1 from Sinorhizobium meliloti 1021
    24% identity, 91% coverage of query (47.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory