Searching for up to 100 curated homologs for Pf6N2E2_4723 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_4723 (399 a.a.)
Found high-coverage hits (≥70%) to 31 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
FADH_PSEPU / P46154 Glutathione-independent formaldehyde dehydrogenase; FALDH; FDH; Formaldehyde dismutase; EC 1.2.1.46; EC 1.2.98.1 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
P46154 formaldehyde dehydrogenase (EC 1.2.1.46) from Pseudomonas putida (see paper)
94% identity, 100% coverage of query (751 bits)
1kolA / P46154 Crystal structure of formaldehyde dehydrogenase (see paper)
94% identity, 99% coverage of query (746 bits)
Q9HTE3 formaldehyde dehydrogenase (EC 1.2.1.46) from Pseudomonas aeruginosa (see paper)
89% identity, 100% coverage of query (707 bits)
4jlwA Crystal structure of formaldehyde dehydrogenase from pseudomonas aeruginosa (see paper)
90% identity, 99% coverage of query (698 bits)
YYCR_BACSU / Q45604 Uncharacterized zinc-type alcohol dehydrogenase-like protein YycR; EC 1.-.-.- from Bacillus subtilis (strain 168) (see paper)
67% identity, 98% coverage of query (536 bits)
A0A6F8QRG1 formaldehyde dismutase (EC 1.2.98.1) from Methylobacterium sp. FD1 (see paper)
58% identity, 98% coverage of query (472 bits)
A0A224AQI3 formaldehyde dismutase (EC 1.2.98.1) from Methylobacterium sp. FD1 (see 2 papers)
56% identity, 98% coverage of query (457 bits)
FDM_PSEPU / Q52078 Formaldehyde dismutase; EC 1.2.98.1 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
58% identity, 99% coverage of query (435 bits)
2dphA / Q52078 Crystal structure of formaldehyde dismutase
58% identity, 99% coverage of query (433 bits)
FADH_METMR / P47734 S-(hydroxymethyl)glutathione dehydrogenase; Alcohol dehydrogenase; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; EC 1.1.1.284; EC 1.1.1.1 from Methylobacter marinus (see paper)
35% identity, 94% coverage of query (186 bits)
YbdR / b0608 putative Zn2+-dependent alcohol dehydrogenase YbdR from Escherichia coli K-12 substr. MG1655 (see paper)
34% identity, 94% coverage of query (174 bits)
ADHB_BACSU / O06012 Uncharacterized zinc-type alcohol dehydrogenase-like protein AdhB; EC 1.-.-.- from Bacillus subtilis (strain 168) (see paper)
34% identity, 95% coverage of query (163 bits)
YHG1_SCHPO / Q9P6I8 Zinc-type alcohol dehydrogenase-like protein C1198.01; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
30% identity, 94% coverage of query (150 bits)
Build an alignment for Pf6N2E2_4723 and 13 homologs with ≥ 30% identity
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4cpdA / B2ZRE3 Alcohol dehydrogenase tadh from thermus sp. Atn1
29% identity, 94% coverage of query (147 bits)
B2ZRE3 alcohol dehydrogenase (EC 1.1.1.1) from Thermus sp. (see paper)
29% identity, 94% coverage of query (147 bits)
Q9HMB6 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Halobacterium sp. (see paper)
31% identity, 94% coverage of query (142 bits)
D4GP73 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Haloferax volcanii (see paper)
30% identity, 94% coverage of query (135 bits)
Q5V676 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Haloarcula marismortui (see paper)
29% identity, 94% coverage of query (126 bits)
ADH_CUPNH / Q0KDL6 Alcohol dehydrogenase; EC 1.1.1.1; EC 1.1.1.4; EC 1.2.1.3 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see 2 papers)
28% identity, 97% coverage of query (106 bits)
Q3C2L6 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Solanum lycopersicum (see paper)
28% identity, 75% coverage of query (100 bits)
DHSO_ARATH / Q9FJ95 Sorbitol dehydrogenase; SDH; Polyol dehydrogenase; Ribitol dehydrogenase; RDH; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.56; EC 1.1.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
28% identity, 76% coverage of query (97.1 bits)
7y9pA / P22144 Xylitol dehydrogenase s96c/s99c/y102c mutant(thermostabilized form) from pichia stipitis (see paper)
31% identity, 72% coverage of query (96.7 bits)
Q5I6M4 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Malus domestica (see paper)
28% identity, 75% coverage of query (95.9 bits)
NAD-SDH / Q9ZR22 D-sorbitol dehydrogenase (EC 1.1.1.14) from Malus domestica (see paper)
28% identity, 75% coverage of query (95.5 bits)
3gfbA / Q5JI69 L-threonine dehydrogenase (tktdh) from the hyperthermophilic archaeon thermococcus kodakaraensis (see paper)
28% identity, 90% coverage of query (95.5 bits)
TDH_THEKO / Q5JI69 L-threonine 3-dehydrogenase; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 2 papers)
Q5JI69 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Thermococcus kodakarensis (see 2 papers)
28% identity, 90% coverage of query (95.5 bits)
1vj0A / Q9WYR7 Crystal structure of alcohol dehydrogenase (tm0436) from thermotoga maritima at 2.00 a resolution
26% identity, 84% coverage of query (73.6 bits)
6ffxA Crystal structure of r. Ruber adh-a, mutant f43h (see paper)
26% identity, 87% coverage of query (71.2 bits)
5o9dA Crystal structure of r. Ruber adh-a, mutant y294f, w295a, y54f, f43h, h39y
26% identity, 87% coverage of query (70.9 bits)
7cyiD / A0A2U1Q018 Crystal structure of alcohol dehydrogenase 1 from artemisia annua
27% identity, 73% coverage of query (64.3 bits)
6ljhA Crystal structure of alcohol dehydrogenase 1 from artemisia annua in complex with NAD+
27% identity, 73% coverage of query (64.3 bits)
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Lawrence Berkeley National Laboratory