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Searching for up to 100 curated homologs for Pf6N2E2_5340 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_5340 (205 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Pog / b3229 stringent starvation protein A from Escherichia coli K-12 substr. MG1655 (see 8 papers)
TC 1.A.12.3.1 / P0ACA3 The bacterial CLIC homologue, stringent starvation protein A, SspA (212 aas; 0 TMSs) [N-terminal Trx domain; C-terminal glutathione S-transferase (GST) domain] from Escherichia coli (strain K12) (see 5 papers)
sspA stringent starvation protein A from Escherichia coli K12 (see 5 papers)
    58% identity, 97% coverage of query (231 bits)

SSPA_COXBU / Q83AY0 Stringent starvation protein A homolog from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see paper)
    51% identity, 97% coverage of query (198 bits)

4qq7A / B4E6Q3 Crystal structure of putative stringent starvation protein a from burkholderia cenocepacia with bound glutathione
    40% identity, 97% coverage of query (152 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    39% identity, 97% coverage of query (146 bits)

6wmtS F. Tularensis rnaps70-(mgla-sspa)-ppgpp-pigr-igla DNA complex (see paper)
    31% identity, 93% coverage of query (97.8 bits)

6wegD Structure of ft (mgla-sspa)-ppgpp-pigr peptide complex
    32% identity, 88% coverage of query (97.8 bits)

Build an alignment

Build an alignment for Pf6N2E2_5340 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

6mhcA / P78417 Glutathione s-transferase omega 1 bound to covalent inhibitor 37 (see paper)
    28% identity, 76% coverage of query (69.7 bits)

GSTO1 / P78417 glutathione transferase, Ω class subunit (EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2) from Homo sapiens (see 2 papers)
GSTO1_HUMAN / P78417 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 5 papers)
P78417 methylarsonate reductase (EC 1.20.4.2); glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 7 papers)
    29% identity, 73% coverage of query (69.7 bits)

6pnoA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n- isopropylsulfamoyl)phenyl)acetamide
    29% identity, 73% coverage of query (69.7 bits)

6pnmA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3- (morpholinosulfonyl)phenyl)acetamide
    29% identity, 73% coverage of query (69.7 bits)

6mhdA Glutathione s-transferase omega 1 bound to covalent inhibitor 44
    28% identity, 76% coverage of query (69.7 bits)

5v3qA Human gsto1-1 complexed with ml175
    29% identity, 73% coverage of query (69.7 bits)

5uehA Structure of gsto1 covalently conjugated to quinolinic acid fluorosulfate
    29% identity, 73% coverage of query (69.7 bits)

4is0A Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of the non-catalytic ligandin site.
    29% identity, 73% coverage of query (69.7 bits)

3vlnA Human glutathione transferase o1-1 c32s mutant in complex with ascorbic acid
    29% identity, 77% coverage of query (69.7 bits)

6pnnA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n-(2- methoxyethyl)-n-methylsulfamoyl)phenyl)acetamide
    28% identity, 76% coverage of query (69.7 bits)

4yqvA Glutathione s-transferase omega 1 bound to covalent inhibitor c4-10
    29% identity, 73% coverage of query (69.7 bits)

4yqmA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-27
    29% identity, 73% coverage of query (69.7 bits)

1eemA Glutathione transferase from homo sapiens
    29% identity, 73% coverage of query (69.7 bits)

6mhbA Glutathione s-transferase omega 1 bound to covalent inhibitor 18
    27% identity, 73% coverage of query (68.2 bits)

4yquA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-31
    27% identity, 73% coverage of query (68.2 bits)

L7QHV5 glutathione transferase (EC 2.5.1.18) from Oncorhynchus kisutch (see paper)
    26% identity, 75% coverage of query (66.6 bits)

Q3MUP2 glutathione transferase (EC 2.5.1.18) from Hordeum vulgare (see paper)
    35% identity, 71% coverage of query (65.5 bits)

A1YW90 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    30% identity, 71% coverage of query (65.5 bits)

A0A4Y5R2M7 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 73% coverage of query (65.1 bits)

O49235 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    30% identity, 71% coverage of query (65.1 bits)

5agyA / I1MJ34 Crystal structure of a tau class gst mutant from glycine (see paper)
    30% identity, 71% coverage of query (65.1 bits)

4topA Glycine max glutathione transferase
    30% identity, 71% coverage of query (65.1 bits)

Q8RW04 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    33% identity, 71% coverage of query (64.7 bits)

3qagA / Q9H4Y5 Human glutathione transferase o2 with glutathione -new crystal form (see paper)
    26% identity, 76% coverage of query (64.7 bits)

gst6 / CAB38120.1 GST6 protein from Zea mays (see paper)
    34% identity, 71% coverage of query (64.3 bits)

Q8RW03 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    34% identity, 71% coverage of query (63.9 bits)

5j4uA / B9I0G5 Crystal structure of a glutathione s-transferase ptgstu30 from populus trichocarpa in complex with gsh
    31% identity, 71% coverage of query (63.9 bits)

B3VQJ6 glutathione transferase (EC 2.5.1.18) from Phanerodontia chrysosporium (see paper)
    27% identity, 75% coverage of query (63.5 bits)

A0A4Y5QZX3 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 90% coverage of query (63.2 bits)

Q9FQE8 glutathione transferase (EC 2.5.1.18) from Glycine max (see paper)
    30% identity, 71% coverage of query (62.4 bits)

4chsA Crystal structure of a tau class glutathione transferase 10 from glycine max
    30% identity, 71% coverage of query (62.4 bits)

GSTU5_ARATH / P46421 Glutathione S-transferase U5; AtGSTU5; AtGSTU1; GST class-tau member 5; Glutathione S-transferase 103-1A; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
P46421 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    28% identity, 73% coverage of query (62.0 bits)

B2ZHM6 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Pinus bungeana (see paper)
    26% identity, 91% coverage of query (61.6 bits)

A0A4Y5QZW9 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    26% identity, 89% coverage of query (61.6 bits)

A0A4Y5QZX0 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 90% coverage of query (61.2 bits)

D2WL48 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    27% identity, 88% coverage of query (61.2 bits)

GSTU19 / Q9ZRW8 glutathione S-transferase U19 monomer (EC 2.5.1.18) from Arabidopsis thaliana (see 6 papers)
GSTUJ_ARATH / Q9ZRW8 Glutathione S-transferase U19; AtGSTU19; GST class-tau member 19; Glutathione S-transferase 8; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
Q9ZRW8 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see 3 papers)
    27% identity, 91% coverage of query (61.2 bits)

Q8RW02 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    32% identity, 71% coverage of query (61.2 bits)

A0A4Y5R0C1 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    30% identity, 78% coverage of query (60.8 bits)

GSTO2_HUMAN / Q9H4Y5 Glutathione S-transferase omega-2; GSTO-2; Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 3 papers)
Q9H4Y5 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 3 papers)
    27% identity, 76% coverage of query (60.8 bits)

A0A023JBX8 glutathione transferase (EC 2.5.1.18) from Macaca fascicularis (see paper)
    27% identity, 76% coverage of query (60.5 bits)

D2WL57 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    31% identity, 76% coverage of query (60.5 bits)

GSTUK_ARATH / Q8L7C9 Glutathione S-transferase U20; AtGSTU20; FIN219-interacting protein 1; GST class-tau member 20; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    25% identity, 91% coverage of query (60.5 bits)

5echB / Q8L7C9 Crystal structure of fin219-fip1 complex with ja and atp (see paper)
    25% identity, 91% coverage of query (60.5 bits)

G7N132 glutathione transferase (EC 2.5.1.18) from Macaca mulatta (see paper)
    27% identity, 76% coverage of query (60.1 bits)

GSTX3_SOYBN / P46417 Glutathione S-transferase 3; EC 2.5.1.18 from Glycine max (Soybean) (Glycine hispida) (see paper)
    25% identity, 92% coverage of query (60.1 bits)

gst7 / CAB38121.1 GST7 protein from Zea mays (see paper)
    30% identity, 76% coverage of query (60.1 bits)

O04437 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    28% identity, 88% coverage of query (60.1 bits)

A0A4Y5R0K8 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    31% identity, 76% coverage of query (59.7 bits)

A0A4Y5QZZ8 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    27% identity, 93% coverage of query (59.3 bits)

5g5aA / Q9SHH7 Glutathione transferase u25 from arabidopsis thaliana in complex with glutathione disulfide
    27% identity, 92% coverage of query (59.3 bits)

Q9SHH7 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    27% identity, 92% coverage of query (59.3 bits)

Q9FUS9 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    30% identity, 73% coverage of query (58.2 bits)

se / Q9VSL3 pyrimidodiazepine synthase subunit (EC 1.5.4.1) from Drosophila melanogaster (see 2 papers)
SEPIA_DROME / Q9VSL3 Pyrimidodiazepine synthase; Protein sepia; EC 1.5.4.1 from Drosophila melanogaster (Fruit fly) (see 2 papers)
    31% identity, 76% coverage of query (57.8 bits)

A0S5Z5 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Sesamum indicum (see paper)
    24% identity, 91% coverage of query (57.8 bits)

GSTO1_PIG / Q9N1F5 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Sus scrofa (Pig) (see paper)
    27% identity, 75% coverage of query (57.4 bits)

A0A4Y5QZX2 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    33% identity, 71% coverage of query (57.4 bits)

8ai8A / Q55139 Crystal structure of glutathione transferase chi 1 from synechocystis sp. Pcc 6803 in complex with glutathione (see paper)
    30% identity, 78% coverage of query (57.4 bits)

Q9FUT0 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    28% identity, 85% coverage of query (57.4 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    28% identity, 91% coverage of query (57.4 bits)

7pkaA Synechocystis sp. Pcc6803 glutathione transferase chi 1, gsoh bound
    30% identity, 78% coverage of query (57.4 bits)

GSTUQ_ARATH / Q9SHH8 Glutathione S-transferase U26; AtGSTU26; GST class-tau member 26; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9SHH8 glutathione transferase (EC 2.5.1.18) from Arabidopsis thaliana (see paper)
    28% identity, 70% coverage of query (57.0 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    28% identity, 91% coverage of query (57.0 bits)

GST1 / AAA29287.1 glutathione transferase from Lucilia cuprina (see paper)
    25% identity, 78% coverage of query (56.6 bits)

A0A4Y5QZX9 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    30% identity, 75% coverage of query (56.6 bits)

DHAR1_ARATH / Q9FWR4 Glutathione S-transferase DHAR1, mitochondrial; Chloride intracellular channel homolog 1; CLIC homolog 1; Glutathione-dependent dehydroascorbate reductase 1; AtDHAR1; GSH-dependent dehydroascorbate reductase 1; mtDHAR; EC 2.5.1.18; EC 1.8.5.1 from Arabidopsis thaliana (Mouse-ear cress) (see 9 papers)
Q9FWR4 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Arabidopsis thaliana (see paper)
TC 1.A.12.2.1 / Q9FWR4 The plant Cl- intracellular channel protein DHAR1 (glutathione dehydrogenase/dehydroascorbate reductase) from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
DHAR1 / SP|Q9LN37 glutathione S-transferase DHAR1, mitochondrial; EC 1.8.5.1 from Arabidopsis thaliana
    26% identity, 88% coverage of query (56.6 bits)

5elgA / Q9FWR4 The structure of dhar1 from arabidopsis thaliana
    26% identity, 88% coverage of query (56.6 bits)

6srbB / A0A1M2V359 Crystal structure of glutathione transferase omega 3c from trametes versicolor (see paper)
    28% identity, 75% coverage of query (56.6 bits)

Q8DMB4 glutathione transferase (EC 2.5.1.18) from Thermosynechococcus vestitus (see paper)
    29% identity, 87% coverage of query (56.2 bits)

6ep7B / Q9M9F1 Arabidopsis thaliana gstu23, gsh bound (see paper)
    27% identity, 94% coverage of query (56.2 bits)

MAAI_RAT / P57113 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Rattus norvegicus (Rat) (see paper)
    28% identity, 87% coverage of query (56.2 bits)

7zvpA Crystal structure of poplar glutathione transferase u19 in complex with glutathione
    30% identity, 80% coverage of query (56.2 bits)

P42860 glutathione transferase (EC 2.5.1.18) from Lucilia cuprina (see paper)
    25% identity, 73% coverage of query (55.8 bits)

SO1671 Maleylacetoacetate isomerase (EC 5.2.1.2) from Shewanella oneidensis MR-1
    30% identity, 76% coverage of query (55.5 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    26% identity, 91% coverage of query (55.5 bits)

1jlvA / Q7KIF2 Anopheles dirus species b glutathione s-transferases 1-3 (see paper)
    25% identity, 76% coverage of query (55.5 bits)

5n9uA Dehydroascorbate reductase 3a from populus trichocarpa complexed with gsh.
    25% identity, 91% coverage of query (54.7 bits)

5myeA / B9HM36 Solution structure of c20s variant of dehydroascorbate reductase 3a from populus trichocarpa in complex with dehydroascorbic acid. (see paper)
    25% identity, 91% coverage of query (54.3 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    26% identity, 91% coverage of query (53.9 bits)

DHAR3_ARATH / Q8LE52 Glutathione S-transferase DHAR3, chloroplastic; Chloride intracellular channel homolog 3; CLIC homolog 3; Glutathione-dependent dehydroascorbate reductase 3; AtDHAR3; ChlDHAR; GSH-dependent dehydroascorbate reductase 3; EC 2.5.1.18; EC 1.8.5.1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    24% identity, 90% coverage of query (52.0 bits)

3wd6A / A8R5V3 Crystal structure of bombyx mori omega-class glutathione transferase in complex with gsh (see paper)
    25% identity, 73% coverage of query (51.6 bits)

7y55A / A0A9E8RZN7 Crystal structure of a glutathione s-transferase tau1 from pinus densata in complex with gsh
    25% identity, 89% coverage of query (51.6 bits)

GSTD1_DROME / P20432 Glutathione S-transferase D1; DDT-dehydrochlorinase; EC 2.5.1.18; EC 4.5.1.1 from Drosophila melanogaster (Fruit fly) (see 2 papers)
    23% identity, 76% coverage of query (50.1 bits)

3makA / P20432 Crystal structure of glutathione transferase dmgstd1 from drosophila melanogaster, in complex with glutathione (see paper)
    23% identity, 76% coverage of query (49.7 bits)

3gh6A / Q9VGA1 Crystal structure of glutathione transferase dmgstd10 from drosophila melanogaster, in complex with glutathione (see paper)
    25% identity, 71% coverage of query (49.7 bits)

3touA / Q8XVV6 Crystal structure of glutathione transferase (target efi-501058) from ralstonia solanacearum gmi1000 with gsh bound
    27% identity, 74% coverage of query (49.7 bits)

4pqiA Crystal structure of glutathione transferase lambda3 from populus trichocarpa (see paper)
    28% identity, 84% coverage of query (48.5 bits)

4isdA / C5A7Z5 Crystal structure of glutathione transferase homolog from burkholderia gl bgr1, target efi-501803, with bound glutathione
    29% identity, 90% coverage of query (48.5 bits)

4iw9B Crystal structure of glutathione s-transferase mha_0454 (target efi- 507015) from mannheimia haemolytica, gsh complex
    25% identity, 79% coverage of query (47.0 bits)

4mk3A / Q1LJ46 Crystal structure of a glutathione transferase family member from cupriavidus metallidurans ch34, target efi-507362, with bound glutathione sulfinic acid (gso2h)
    25% identity, 91% coverage of query (47.0 bits)

7dw4A / A0A4Y5R032 Crystal structure of a glutathione s-transferase mutant sbgstu6(i55t) from salix babylonica in complex with glutathione
    27% identity, 72% coverage of query (45.8 bits)

4ielB / Q0B681 Crystal structure of a glutathione s-transferase family protein from burkholderia ambifaria, target efi-507141, with bound glutathione
    27% identity, 74% coverage of query (45.4 bits)

8ax0A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with sodium nitroprusside
    25% identity, 80% coverage of query (44.3 bits)

8awzA / A0A384E145 Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with dinitrosyl glutathionyl iron complex (dngic) (see paper)
    25% identity, 80% coverage of query (44.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory