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Searching for up to 100 curated homologs for Pf6N2E2_5438 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_5438 (174 a.a.)

Found high-coverage hits (≥70%) to 48 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4n27A / Q2YQG1 X-ray structure of brucella abortus rica (see paper)
    59% identity, 89% coverage of query (200 bits)

7zw9A / Q63SQ4 Crystal structure of a gamma-carbonic anhydrase from the pathogenic bacterium burkholderia pseudomallei (see paper)
    52% identity, 96% coverage of query (179 bits)

O59257 carbonic anhydrase (EC 4.2.1.1) from Pyrococcus horikoshii (see 2 papers)
2fkoA / O59257 Structure of ph1591 from pyrococcus horikoshii ot3 (see paper)
    51% identity, 95% coverage of query (167 bits)

1v3wA Structure of ferripyochelin binding protein from pyrococcus horikoshii ot3
    51% identity, 95% coverage of query (167 bits)

6iveA / Q5SH51 Molecular structure of a thermostable and a zinc ion binding gamma- class carbonic anhydrase (see paper)
    43% identity, 97% coverage of query (159 bits)

CAG_GEOKA / Q5KW03 Carbonic anhydrase; Gamma-carbonic anhydrase; Cag; EC 4.2.1.1 from Geobacillus kaustophilus (strain HTA426) (see 2 papers)
    41% identity, 86% coverage of query (126 bits)

3vnpA / Q5KW03 Crystal structure of hypothetical protein (gk2848) from geobacillus kaustophilus
    41% identity, 86% coverage of query (126 bits)

at5g66510 / Q94AU7 NADH-ubiquinone oxidoreductase subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
GCA3_ARATH / Q94AU7 Gamma carbonic anhydrase 3, mitochondrial; AtCA3; GAMMA CA3; EC 4.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    38% identity, 88% coverage of query (123 bits)

8e73G2 / A0A1S3U544 8e73G2 (see paper)
    37% identity, 86% coverage of query (122 bits)

3r3rA / Q8ZLN3 Structure of the yrda ferripyochelin binding protein from salmonella enterica
    38% identity, 88% coverage of query (120 bits)

YrdA / b3279 hexapeptide repeats-containing protein YrdA from Escherichia coli K-12 substr. MG1655 (see 2 papers)
    37% identity, 89% coverage of query (119 bits)

at1g47260 / Q9C6B3 NADH-ubiquinone oxidoreductase subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
GCA2_ARATH / Q9C6B3 Gamma carbonic anhydrase 2, mitochondrial; AtCA2; GAMMA CA2; Transcription factor APFI; EC 4.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
Q9C6B3 carbonic anhydrase (EC 4.2.1.1) from Arabidopsis thaliana (see paper)
    36% identity, 90% coverage of query (119 bits)

7aqqy / Q9C6B3 Cryo-em structure of arabidopsis thaliana complex-i (membrane core) (see paper)
    36% identity, 90% coverage of query (119 bits)

8gpmA / A0A6F8THQ5 Acinetobacter baumannii carbonic anhydrase
    42% identity, 93% coverage of query (119 bits)

8bpxy Cytochrome b-c1 complex subunit Rieske-1, mitochondrial
    36% identity, 90% coverage of query (119 bits)

8befy Cryo-em structure of the arabidopsis thaliana i+iii2 supercomplex (ci membrane core)
    36% identity, 90% coverage of query (119 bits)

7ar7y Cryo-em structure of arabidopsis thaliana complex-i (open conformation)
    36% identity, 90% coverage of query (119 bits)

8gppA Acinetobacter baumannii carbonic anhydrase paay
    42% identity, 93% coverage of query (119 bits)

3tioF / P0A9W9 Crystal structures of yrda from escherichia coli, a homologous protein of gamma-class carbonic anhydrase, show possible allosteric conformations (see paper)
    39% identity, 83% coverage of query (118 bits)

6sc4B / A0A133ULQ3 Gamma-carbonic anhydrase from the haloarchaeon halobacterium sp. (see paper)
    32% identity, 97% coverage of query (118 bits)

GCA1_ARATH / Q9FWR5 Gamma carbonic anhydrase 1, mitochondrial; AtCA1; GAMMA CA1; EC 4.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9FWR5 carbonic anhydrase (EC 4.2.1.1) from Arabidopsis thaliana (see paper)
    35% identity, 87% coverage of query (118 bits)

7aqqz / Q9FWR5 Cryo-em structure of arabidopsis thaliana complex-i (membrane core) (see paper)
    35% identity, 87% coverage of query (118 bits)

7a23p Plant mitochondrial respiratory complex i
    35% identity, 87% coverage of query (118 bits)

YdbZ / b1400 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA thioesterase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
paaY / P77181 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA thioesterase from Escherichia coli (strain K12) (see 4 papers)
    39% identity, 92% coverage of query (112 bits)

3ixcA / Q2GIS1 Crystal structure of hexapeptide transferase family protein from anaplasma phagocytophilum
    36% identity, 86% coverage of query (108 bits)

CaiE / b0035 putative transferase CaiE from Escherichia coli K-12 substr. MG1655 (see 2 papers)
caiE / P39206 putative transferase CaiE from Escherichia coli (strain K12) (see paper)
CAIE_ECOLI / P39206 Carnitine operon protein CaiE from Escherichia coli (strain K12) (see paper)
    33% identity, 94% coverage of query (99.0 bits)

at5g63510 / Q9FMV1 NADH-ubiquinone oxidoreductase subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
GCAL1_ARATH / Q9FMV1 Gamma carbonic anhydrase-like 1, mitochondrial; AtCAL1; GAMMA CAL1 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9FMV1 carbonic anhydrase (EC 4.2.1.1) from Arabidopsis thaliana (see paper)
    32% identity, 89% coverage of query (91.7 bits)

8bpxx Cytochrome b-c1 complex subunit Rieske-1, mitochondrial
    32% identity, 89% coverage of query (91.3 bits)

at3g48680 / Q9SMN1 NADH-ubiquinone oxidoreductase subunit (EC 7.1.1.2) from Arabidopsis thaliana (see paper)
GCAL2_ARATH / Q9SMN1 Gamma carbonic anhydrase-like 2, mitochondrial; AtCAL2; GAMMA CAL2 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9SMN1 carbonic anhydrase (EC 4.2.1.1) from Arabidopsis thaliana (see paper)
    32% identity, 89% coverage of query (90.9 bits)

K4N028 carbonic anhydrase (EC 4.2.1.1) from Serratia sp. ISTD04 (see paper)
    32% identity, 70% coverage of query (77.8 bits)

Build an alignment

Build an alignment for Pf6N2E2_5438 and 30 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

C3W4Q7 carbonic anhydrase (EC 4.2.1.1) from Methanosarcina thermophila (see paper)
    27% identity, 83% coverage of query (71.2 bits)

1qrlA / P40881 A closer look at the active site of gamma-carbonic anhydrases: high resolution crystallographic studies of the carbonic anhydrase from methanosarcina thermophila (see paper)
    33% identity, 78% coverage of query (68.9 bits)

CAH_METTT / P40881 Carbonic anhydrase; CA; Cam; EC 4.2.1.1 from Methanosarcina thermophila (strain ATCC 43570 / DSM 1825 / OCM 12 / VKM B-1830 / TM-1) (see 3 papers)
P40881 carbonic anhydrase (EC 4.2.1.1) from Methanosarcina thermophila (see 9 papers)
    33% identity, 78% coverage of query (68.9 bits)

1qq0A Cobalt substituted carbonic anhydrase from methanosarcina thermophila
    33% identity, 78% coverage of query (68.9 bits)

CCMM_NOSS1 / Q8YYI3 Carboxysome assembly protein CcmM; CcmM58; M58; Carbon dioxide concentrating mechanism protein CcmM; Carbonic anhydrase; EC 4.2.1.1 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see 2 papers)
    31% identity, 72% coverage of query (67.0 bits)

CCMM_SYNY3 / P72758 Carboxysome assembly protein CcmM; CcmM73; M73; Carbon dioxide concentrating mechanism protein CcmM from Synechocystis sp. (strain PCC 6803 / Kazusa) (see 2 papers)
P72758 carbonic anhydrase (EC 4.2.1.1) from Synechocystis sp. PCC 6803 (see paper)
    31% identity, 74% coverage of query (56.6 bits)

CCMM_SYNE7 / Q03513 Carboxysome assembly protein CcmM; CcmM58; M58; Carbon dioxide concentrating mechanism protein CcmM; Carboxysome shell associated protein CcmM from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see 11 papers)
    27% identity, 74% coverage of query (53.5 bits)

DCTN5_PIG / A0A286ZK88 Dynactin subunit 5 from Sus scrofa (Pig) (see 4 papers)
DCTN5_HUMAN / Q9BTE1 Dynactin subunit 5; Dynactin subunit p25 from Homo sapiens (Human) (see paper)
7z8mV / A0A4X1UWQ6 The pointed end complex of dynactin bound to bicdr1 (see paper)
    24% identity, 86% coverage of query (48.9 bits)

4eaaA / O85353 X-ray crystal structure of the h141n mutant of perosamine n- acetyltransferase from caulobacter crescentus in complex with coa and gdp-perosamine (see paper)
    28% identity, 73% coverage of query (48.9 bits)

4ea9A X-ray structure of gdp-perosamine n-acetyltransferase in complex with transition state analog at 0.9 angstrom resolution
    28% identity, 73% coverage of query (48.1 bits)

4ea8A X-ray crystal structure of perb from caulobacter crescentus in complex with coenzyme a and gdp-n-acetylperosamine at 1 angstrom resolution
    28% identity, 73% coverage of query (48.1 bits)

CCMM_THEVB / Q8DKB5 Carboxysome assembly protein CcmM; CcmM70; M70; Carbon dioxide concentrating mechanism protein CcmM; Carbonic anhydrase; EC 4.2.1.1 from Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1) (see 2 papers)
    28% identity, 72% coverage of query (46.6 bits)

P95377 UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase (EC 2.3.1.191) from Neisseria meningitidis (see paper)
    30% identity, 84% coverage of query (45.8 bits)

3kwcA / Q8DKB5 Oxidized, active structure of the beta-carboxysomal gamma-carbonic anhydrase, ccmm (see paper)
    28% identity, 72% coverage of query (45.8 bits)

LacA / b0342 galactoside O-acetyltransferase (EC 2.3.1.18) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lacA / P07464 galactoside O-acetyltransferase (EC 2.3.1.18) from Escherichia coli (strain K12) (see 19 papers)
THGA_ECOLI / P07464 Galactoside O-acetyltransferase; GAT; Acetyl-CoA:galactoside 6-O-acetyltransferase; Thiogalactoside acetyltransferase; Thiogalactoside transacetylase; EC 2.3.1.18 from Escherichia coli (strain K12) (see 5 papers)
P07464 galactoside O-acetyltransferase (EC 2.3.1.18) from Escherichia coli (see paper)
    29% identity, 79% coverage of query (45.4 bits)

1kruA / P07464 Galactoside acetyltransferase in complex with iptg and coenzyme a (see paper)
    29% identity, 79% coverage of query (45.4 bits)

1krvA Galactoside acetyltransferase in complex with coa and pnp-beta-gal
    29% identity, 79% coverage of query (45.4 bits)

1krrA Galactoside acetyltransferase in complex with acetyl-coenzyme a
    29% identity, 79% coverage of query (45.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory